Reactome | phospho-DCC [plasma membrane]

phospho-DCC [plasma membrane]

Stable Identifier

R-CFA-374552

Type

Protein [EntityWithAccessionedSequence]

Species

Canis familiaris

Compartment

plasma membrane

Synonyms

p-Y1420-DCC, F1PAZ4

Locations in the PathwayBrowser

Expand all

Developmental Biology (Canis familiaris)

- Nervous system development (Canis familiaris)
  - Axon guidance (Canis familiaris)
    - Netrin-1 signaling (Canis familiaris)
      - DCC mediated attractive signaling (Canis familiaris)
        
        Activation of Cdc42 (Canis familiaris)
        
        NTN1:p-Y1420-DCC oligomer:p-Y397-PTK2:MyrG-p-Y419-SRC,MyrG-p-Y420-FYN:NCK1:DOCK1,TRIO [plasma membrane] (Canis familiaris)
        
        NTN1:p-Y1420-DCC oligomer:p-Y397-PTK2:MyrG-p-Y419-SRC,MyrG-p-Y420-FYN:NCK1 [plasma membrane] (Canis familiaris)
        
        NTN1:p-Y1420-DCC oligomer:p-Y397-PTK2:MyrG-p-Y419-SRC,MyrG-p-Y420-FYN [plasma membrane] (Canis familiaris)
        
        NTN1:p-Y1420-DCC oligomer:p-Y397-PTK2 [plasma membrane] (Canis familiaris)
        
        NTN1:p-Y1420-DCC oligomer [plasma membrane] (Canis familiaris)
        
        phospho-DCC [plasma membrane] (Canis familiaris)
        
        NTN1:p-Y1420-DCC oligomer:p-Y397-PTK2:MyrG-p-Y419-SRC,MyrG-p-Y420-FYN:NCK1:DOCK1,TRIO:CDC42:GTP [plasma membrane] (Canis familiaris)
        
        NTN1:p-Y1420-DCC oligomer:p-Y397-PTK2:MyrG-p-Y419-SRC,MyrG-p-Y420-FYN:NCK1:DOCK1,TRIO [plasma membrane] (Canis familiaris)
        
        NTN1:p-Y1420-DCC oligomer:p-Y397-PTK2:MyrG-p-Y419-SRC,MyrG-p-Y420-FYN:NCK1 [plasma membrane] (Canis familiaris)
        
        NTN1:p-Y1420-DCC oligomer:p-Y397-PTK2:MyrG-p-Y419-SRC,MyrG-p-Y420-FYN [plasma membrane] (Canis familiaris)
        
        NTN1:p-Y1420-DCC oligomer:p-Y397-PTK2 [plasma membrane] (Canis familiaris)
        
        NTN1:p-Y1420-DCC oligomer [plasma membrane] (Canis familiaris)
        
        phospho-DCC [plasma membrane] (Canis familiaris)
        
        Activation of Rac1 (Canis familiaris)
        
        NTN1:p-Y1420-DCC oligomer:p-Y397-PTK2:MyrG-p-Y419-SRC,MyrG-p-Y420-FYN:NCK1:DOCK1,TRIO [plasma membrane] (Canis familiaris)
        
        NTN1:p-Y1420-DCC oligomer:p-Y397-PTK2:MyrG-p-Y419-SRC,MyrG-p-Y420-FYN:NCK1 [plasma membrane] (Canis familiaris)
        
        NTN1:p-Y1420-DCC oligomer:p-Y397-PTK2:MyrG-p-Y419-SRC,MyrG-p-Y420-FYN [plasma membrane] (Canis familiaris)
        
        NTN1:p-Y1420-DCC oligomer:p-Y397-PTK2 [plasma membrane] (Canis familiaris)
        
        NTN1:p-Y1420-DCC oligomer [plasma membrane] (Canis familiaris)
        
        phospho-DCC [plasma membrane] (Canis familiaris)
        
        NTN1:p-Y1420-DCC oligomer:p-Y397-PTK2:MyrG-p-Y419-SRC,MyrG-p-Y420-FYN:NCK1:DOCK1,TRIO:RAC1:GTP [plasma membrane] (Canis familiaris)
        
        NTN1:p-Y1420-DCC oligomer:p-Y397-PTK2:MyrG-p-Y419-SRC,MyrG-p-Y420-FYN:NCK1:DOCK1,TRIO [plasma membrane] (Canis familiaris)
        
        NTN1:p-Y1420-DCC oligomer:p-Y397-PTK2:MyrG-p-Y419-SRC,MyrG-p-Y420-FYN:NCK1 [plasma membrane] (Canis familiaris)
        
        NTN1:p-Y1420-DCC oligomer:p-Y397-PTK2:MyrG-p-Y419-SRC,MyrG-p-Y420-FYN [plasma membrane] (Canis familiaris)
        
        NTN1:p-Y1420-DCC oligomer:p-Y397-PTK2 [plasma membrane] (Canis familiaris)
        
        NTN1:p-Y1420-DCC oligomer [plasma membrane] (Canis familiaris)
        
        phospho-DCC [plasma membrane] (Canis familiaris)
        
        DCC interacting NCK-1 (Canis familiaris)
        
        NTN1:p-Y1420-DCC oligomer:p-Y397-PTK2:MyrG-p-Y419-SRC,MyrG-p-Y420-FYN [plasma membrane] (Canis familiaris)
        
        NTN1:p-Y1420-DCC oligomer:p-Y397-PTK2 [plasma membrane] (Canis familiaris)
        
        NTN1:p-Y1420-DCC oligomer [plasma membrane] (Canis familiaris)
        
        phospho-DCC [plasma membrane] (Canis familiaris)
        
        NTN1:p-Y1420-DCC oligomer:p-Y397-PTK2:MyrG-p-Y419-SRC,MyrG-p-Y420-FYN:NCK1 [plasma membrane] (Canis familiaris)
        
        NTN1:p-Y1420-DCC oligomer:p-Y397-PTK2:MyrG-p-Y419-SRC,MyrG-p-Y420-FYN [plasma membrane] (Canis familiaris)
        
        NTN1:p-Y1420-DCC oligomer:p-Y397-PTK2 [plasma membrane] (Canis familiaris)
        
        NTN1:p-Y1420-DCC oligomer [plasma membrane] (Canis familiaris)
        
        phospho-DCC [plasma membrane] (Canis familiaris)
        
        Phosphorylation of DCC by Fyn (Canis familiaris)
        
        NTN1:p-Y1420-DCC oligomer:p-Y397-PTK2:MyrG-p-Y419-SRC,MyrG-p-Y420-FYN [plasma membrane] (Canis familiaris)
        
        NTN1:p-Y1420-DCC oligomer:p-Y397-PTK2 [plasma membrane] (Canis familiaris)
        
        NTN1:p-Y1420-DCC oligomer [plasma membrane] (Canis familiaris)
        
        phospho-DCC [plasma membrane] (Canis familiaris)
        
        RhoGTPase GEF's recruited to DCC (Canis familiaris)
        
        NTN1:p-Y1420-DCC oligomer:p-Y397-PTK2:MyrG-p-Y419-SRC,MyrG-p-Y420-FYN:NCK1 [plasma membrane] (Canis familiaris)
        
        NTN1:p-Y1420-DCC oligomer:p-Y397-PTK2:MyrG-p-Y419-SRC,MyrG-p-Y420-FYN [plasma membrane] (Canis familiaris)
        
        NTN1:p-Y1420-DCC oligomer:p-Y397-PTK2 [plasma membrane] (Canis familiaris)
        
        NTN1:p-Y1420-DCC oligomer [plasma membrane] (Canis familiaris)
        
        phospho-DCC [plasma membrane] (Canis familiaris)
        
        NTN1:p-Y1420-DCC oligomer:p-Y397-PTK2:MyrG-p-Y419-SRC,MyrG-p-Y420-FYN:NCK1:DOCK1,TRIO [plasma membrane] (Canis familiaris)
        
        NTN1:p-Y1420-DCC oligomer:p-Y397-PTK2:MyrG-p-Y419-SRC,MyrG-p-Y420-FYN:NCK1 [plasma membrane] (Canis familiaris)
        
        NTN1:p-Y1420-DCC oligomer:p-Y397-PTK2:MyrG-p-Y419-SRC,MyrG-p-Y420-FYN [plasma membrane] (Canis familiaris)
        
        NTN1:p-Y1420-DCC oligomer:p-Y397-PTK2 [plasma membrane] (Canis familiaris)
        
        NTN1:p-Y1420-DCC oligomer [plasma membrane] (Canis familiaris)
        
        phospho-DCC [plasma membrane] (Canis familiaris)

External Reference Information

External Reference

UniProt:F1PAZ4

Gene Names

DCC

Reference Genes

ENSEMBL:ENSCAFG00000000157

ENSEMBL_canis_lupus_familiaris_GENE:ENSCAFG00000000157 DCC

Other Identifiers

483976

CfaAffx.1208.1.S1_s_at

GO:0000902

GO:0001764

GO:0003674

GO:0005042

GO:0005575

GO:0005886

GO:0006915

GO:0007165

GO:0007267

GO:0007399

GO:0007411

GO:0008150

GO:0008219

GO:0016020

GO:0016021

GO:0021965

GO:0030154

GO:0030424

GO:0033563

GO:0033564

GO:0038007

GO:0040011

GO:0043226

GO:0048856

GO:0048870

GO:0098685

GO:0099061

GO:0099170

GO:1901214

Participates

as a component of

NTN1:p-Y1420-DCC oligomer [plasma membrane] (Canis familiaris)

Other forms of this molecule

DCC [cytosol]

DCC [plasma membrane]

Inferred From

p-Y1420-DCC [plasma membrane] (Homo sapiens)

Modified Residues

Name

O4'-phospho-L-tyrosine at 1420 (in Homo sapiens)

Coordinate

1420

PsiMod Name

O4'-phospho-L-tyrosine [MOD:00048]

PsiMod Definition

A protein modification that effectively converts an L-tyrosine residue to O4'-phospho-L-tyrosine.

Cross References

OpenTargets

ENSG00000187323

Ensembl

ENSCAFT00000000254, ENSCAFP00000000229, ENSCAFG00000000157

VGNC

39799

Cite Us!