Reactome | ARHGEF7 [cytosol]

ARHGEF7 [cytosol]

Stable Identifier

R-CFA-430346

Type

Protein [EntityWithAccessionedSequence]

Species

Canis familiaris

Compartment

cytosol

Synonyms

ARHGEF7, E2R427

Locations in the PathwayBrowser

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Developmental Biology (Canis familiaris)

- Nervous system development (Canis familiaris)
  - Axon guidance (Canis familiaris)
    - EPH-Ephrin signaling (Canis familiaris)
      - Ephrin signaling (Canis familiaris)
        
        GIT1 binds bPIX (Canis familiaris)
        
        ARHGEF7 [cytosol] (Canis familiaris)
        
        EPHBs:p-3Y-EFNBs:SRC,FYN:GRB4:p-GIT1:ARHGEF7 [plasma membrane] (Canis familiaris)
        
        ARHGEF7 [cytosol] (Canis familiaris)
        
        PAK binds RAC and bPIX (Canis familiaris)
        
        EPHBs:p-3Y-EFNBs:SRC,FYN:GRB4:p-GIT1:ARHGEF7:RAC1:GTP [plasma membrane] (Canis familiaris)
        
        EPHBs:p-3Y-EFNBs:SRC,FYN:GRB4:p-GIT1:ARHGEF7 [plasma membrane] (Canis familiaris)
        
        ARHGEF7 [cytosol] (Canis familiaris)
        
        EPHBs:p-3Y-EFNBs:SRC,FYN:GRB4:p-GIT1:ARHGEF7:RAC1:GTP:PAK1,3 [plasma membrane] (Canis familiaris)
        
        EPHBs:p-3Y-EFNBs:SRC,FYN:GRB4:p-GIT1:ARHGEF7:RAC1:GTP [plasma membrane] (Canis familiaris)
        
        EPHBs:p-3Y-EFNBs:SRC,FYN:GRB4:p-GIT1:ARHGEF7 [plasma membrane] (Canis familiaris)
        
        ARHGEF7 [cytosol] (Canis familiaris)
        
        PAKs autophosphorylate (Canis familiaris)
        
        EPHBs:p-3Y-EFNBs:SRC,FYN:GRB4:p-GIT1:ARHGEF7:RAC1:GTP:PAK1,3 [plasma membrane] (Canis familiaris)
        
        EPHBs:p-3Y-EFNBs:SRC,FYN:GRB4:p-GIT1:ARHGEF7:RAC1:GTP [plasma membrane] (Canis familiaris)
        
        EPHBs:p-3Y-EFNBs:SRC,FYN:GRB4:p-GIT1:ARHGEF7 [plasma membrane] (Canis familiaris)
        
        ARHGEF7 [cytosol] (Canis familiaris)
        
        EPHBs:p-3Y-EFNBs:SRC,FYN:GRB4:p-GIT1:ARHGEF7:RAC1:GTP:p-PAK1,3 [plasma membrane] (Canis familiaris)
        
        EPHBs:p-3Y-EFNBs:SRC,FYN:GRB4:p-GIT1:ARHGEF7:RAC1:GTP [plasma membrane] (Canis familiaris)
        
        EPHBs:p-3Y-EFNBs:SRC,FYN:GRB4:p-GIT1:ARHGEF7 [plasma membrane] (Canis familiaris)
        
        ARHGEF7 [cytosol] (Canis familiaris)
        
        PAKs phosphorylate MLC (Canis familiaris)
        
        EPHBs:p-3Y-EFNBs:SRC,FYN:GRB4:p-GIT1:ARHGEF7:RAC1:GTP:p-PAK1,3 [plasma membrane] (Canis familiaris)
        
        EPHBs:p-3Y-EFNBs:SRC,FYN:GRB4:p-GIT1:ARHGEF7:RAC1:GTP [plasma membrane] (Canis familiaris)
        
        EPHBs:p-3Y-EFNBs:SRC,FYN:GRB4:p-GIT1:ARHGEF7 [plasma membrane] (Canis familiaris)
        
        ARHGEF7 [cytosol] (Canis familiaris)

External Reference Information

External Reference

UniProt:E2R427

Gene Names

ARHGEF7

Reference Genes

ENSEMBL:ENSCAFG00000006116

ENSEMBL_canis_lupus_familiaris_GENE:ENSCAFG00000006116 ARHGEF7

Other Identifiers

485552

CfaAffx.10175.1.S1_s_at

GO:0003674

GO:0005085

GO:0005575

GO:0007165

GO:0008150

GO:0019899

GO:0030027

GO:0035556

Participant Of

input

GIT1 binds bPIX

hasComponent

hasMember

GEFs [cytosol]

Inferred From

ARHGEF7 [cytosol] (Homo sapiens)

Cross References

OpenTargets

ENSG00000102606

Ensembl

ENSCAFG00000006116, ENSCAFP00000009209, ENSCAFT00000009923

VGNC

54920