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NEDD8 [cytosol]
Stable Identifier
R-CFA-4419895
Type
Protein [EntityWithAccessionedSequence]
Species
Canis familiaris
Compartment
cytosol
Synonyms
C111-AcM-UBE2M-G76-NEDD8, A0A8I3N2C0
Locations in the PathwayBrowser
Expand all
Metabolism of proteins (Canis familiaris)
Post-translational protein modification (Canis familiaris)
Neddylation (Canis familiaris)
AcM-UBE2M transfers NEDD8 to CRL1 E3 ubiquitin ligase complex (Canis familiaris)
NEDD8-AcM-UBE2M:CRL1 E3 ubiquitin ligase:COMMDs:CCDC22:DCUN1Ds [cytosol] (Canis familiaris)
NEDD8-AcM-UBE2M [cytosol] (Canis familiaris)
NEDD8 [cytosol] (Canis familiaris)
AcM-UBE2M transfers NEDD8 to CRL2 E3 ubiquitin ligase complex (Canis familiaris)
NEDD8-AcM-UBE2M:CRL2 E3 ubiquitin ligase:COMMDs:CCDC22:DCUN1D1,2,4,5 [cytosol] (Canis familiaris)
NEDD8-AcM-UBE2M [cytosol] (Canis familiaris)
NEDD8 [cytosol] (Canis familiaris)
AcM-UBE2M transfers NEDD8 to CRL3 E3 ubiquitin ligase complex (Canis familiaris)
NEDD8-AcM-UBE2M:CRL3 E3 ubiquitin ligase :DCUN1D1,2,4,5 [cytosol] (Canis familiaris)
NEDD8-AcM-UBE2M [cytosol] (Canis familiaris)
NEDD8 [cytosol] (Canis familiaris)
AcM-UBE2M transfers NEDD8 to CUL9:RBX1 (Canis familiaris)
NEDD8-AcM-UBE2M:CUL9:RBX1 [cytosol] (Canis familiaris)
NEDD8-AcM-UBE2M [cytosol] (Canis familiaris)
NEDD8 [cytosol] (Canis familiaris)
NEDD8:AcM-UBE2M binds CRL1 E3 ubiquitin ligase complex (Canis familiaris)
NEDD8-AcM-UBE2M [cytosol] (Canis familiaris)
NEDD8 [cytosol] (Canis familiaris)
NEDD8-AcM-UBE2M:CRL1 E3 ubiquitin ligase:COMMDs:CCDC22:DCUN1Ds [cytosol] (Canis familiaris)
NEDD8-AcM-UBE2M [cytosol] (Canis familiaris)
NEDD8 [cytosol] (Canis familiaris)
NEDD8:AcM-UBE2M binds CRL2 E3 ubiquitin ligase complex (Canis familiaris)
NEDD8-AcM-UBE2M [cytosol] (Canis familiaris)
NEDD8 [cytosol] (Canis familiaris)
NEDD8-AcM-UBE2M:CRL2 E3 ubiquitin ligase:COMMDs:CCDC22:DCUN1D1,2,4,5 [cytosol] (Canis familiaris)
NEDD8-AcM-UBE2M [cytosol] (Canis familiaris)
NEDD8 [cytosol] (Canis familiaris)
NEDD8:AcM-UBE2M binds CRL3 E3 ubiquitin ligase complex (Canis familiaris)
NEDD8-AcM-UBE2M [cytosol] (Canis familiaris)
NEDD8 [cytosol] (Canis familiaris)
NEDD8-AcM-UBE2M:CRL3 E3 ubiquitin ligase :DCUN1D1,2,4,5 [cytosol] (Canis familiaris)
NEDD8-AcM-UBE2M [cytosol] (Canis familiaris)
NEDD8 [cytosol] (Canis familiaris)
NEDD8:AcM-UBE2M binds CUL9:RBX1 ubiquitin ligase complex (Canis familiaris)
NEDD8-AcM-UBE2M [cytosol] (Canis familiaris)
NEDD8 [cytosol] (Canis familiaris)
NEDD8-AcM-UBE2M:CUL9:RBX1 [cytosol] (Canis familiaris)
NEDD8-AcM-UBE2M [cytosol] (Canis familiaris)
NEDD8 [cytosol] (Canis familiaris)
Transfer of NEDD8 to AcM-UBE2M (Canis familiaris)
NEDD8-AcM-UBE2M [cytosol] (Canis familiaris)
NEDD8 [cytosol] (Canis familiaris)
Signal Transduction (Canis familiaris)
Signaling by TGFB family members (Canis familiaris)
Signaling by TGF-beta Receptor Complex (Canis familiaris)
TGF-beta receptor signaling activates SMADs (Canis familiaris)
CBL neddylates TGFBR2 (Canis familiaris)
NEDD8-AcM-UBE2M [cytosol] (Canis familiaris)
NEDD8 [cytosol] (Canis familiaris)
External Reference Information
External Reference
UniProt:A0A8I3N2C0
Gene Names
NEDD8
Reference Genes
BioGPS Gene:480265 NEDD8
ENSEMBL:ENSCAFG00845006300.1
KEGG:cfa:480265 NEDD8
Monarch:480265 NEDD8
NCBI Gene:480265 NEDD8
UCSC:A0A8I3N2C0 NEDD8
Reference Transcript
RefSeq:XM_537389.5 NEDD8
Other Identifiers
Cfa.734.1.A1_s_at
Cfa.734.2.A1_a_at
GO:0005634
GO:0005654
GO:0005737
GO:0005829
GO:0006355
GO:0006357
GO:0008104
GO:0019941
GO:0030162
GO:0031386
GO:0031625
GO:0043226
GO:0045116
GO:0098978
GO:0150052
Participates
as a component of
NEDD8-AcM-UBE2M [cytosol] (Canis familiaris)
Other forms of this molecule
NEDD8 [nucleoplasm]
NEDD8 [nucleoplasm]
NEDD8 [cytosol]
NEDD8 [cytosol]
NEDD8 [cytosol]
NEDD8 [cytosol]
NEDD8 [cytosol]
Inferred From
C111-AcM-UBE2M-G76-NEDD8 [cytosol]
(Homo sapiens)
Modified Residues
Name
Inter-chain Crosslink via S-(glycyl)-L-cysteine (Cys-Gly) at 76 and 111 (in Homo sapiens)
Coordinate
76
PsiMod Name
S-(glycyl)-L-cysteine (Cys-Gly)
PsiMod Definition
A protein modification that effectively crosslinks an L-cysteine residue and a glycine residue by a thioester bond to form S-glycyl-L-cysteine.
Cross References
RefSeq
XP_537389.2
ENSEMBL
ENSCAFT00845011168
,
ENSCAFP00845008710
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