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PAK1 dimer [cytosol]
Stable Identifier
R-CFA-445002
Type
Complex
Species
Canis familiaris
Compartment
cytosol
Locations in the PathwayBrowser
Expand all
Developmental Biology (Canis familiaris)
Nervous system development (Canis familiaris)
Axon guidance (Canis familiaris)
EPH-Ephrin signaling (Canis familiaris)
EPHB-mediated forward signaling (Canis familiaris)
PAK1 binds RAC1:GTP (Canis familiaris)
PAK1 dimer [cytosol] (Canis familiaris)
L1CAM interactions (Canis familiaris)
Signal transduction by L1 (Canis familiaris)
Interaction of PAK1 with Rac1-GTP (Canis familiaris)
PAK1 dimer [cytosol] (Canis familiaris)
Semaphorin interactions (Canis familiaris)
Sema3A PAK dependent Axon repulsion (Canis familiaris)
Activation of PAK by Rac1 (Canis familiaris)
PAK1,2,3 dimer [cytosol] (Canis familiaris)
PAK1 dimer [cytosol] (Canis familiaris)
Immune System (Canis familiaris)
Adaptive Immune System (Canis familiaris)
Costimulation by the CD28 family (Canis familiaris)
CD28 co-stimulation (Canis familiaris)
CD28 dependent Vav1 pathway (Canis familiaris)
Activation of PAKs by RAC1 and CDC42 (Canis familiaris)
PAK1,2,3 dimer [cytosol] (Canis familiaris)
PAK1 dimer [cytosol] (Canis familiaris)
Innate Immune System (Canis familiaris)
Fc epsilon receptor (FCERI) signaling (Canis familiaris)
FCERI mediated MAPK activation (Canis familiaris)
Autophosphorylation of PAK (Canis familiaris)
PAK dimer [cytosol] (Canis familiaris)
PAK1 dimer [cytosol] (Canis familiaris)
p-5Y-LAT:GRB2:SOS1:GADS:p-Y113,Y128,Y145-SLP-76:PLCG1:PIP3:p-VAV:RAC1-GTP:PAK dimer [plasma membrane] (Canis familiaris)
PAK dimer [cytosol] (Canis familiaris)
PAK1 dimer [cytosol] (Canis familiaris)
Recruitment of PAK to the membrane by binding active RAC1 (Canis familiaris)
PAK dimer [cytosol] (Canis familiaris)
PAK1 dimer [cytosol] (Canis familiaris)
p-5Y-LAT:GRB2:SOS1:GADS:p-Y113,Y128,Y145-SLP-76:PLCG1:PIP3:p-VAV:RAC1-GTP:PAK dimer [plasma membrane] (Canis familiaris)
PAK dimer [cytosol] (Canis familiaris)
PAK1 dimer [cytosol] (Canis familiaris)
Fcgamma receptor (FCGR) dependent phagocytosis (Canis familiaris)
Regulation of actin dynamics for phagocytic cup formation (Canis familiaris)
RAC1 and CDC42 activate PAK1 (Canis familiaris)
PAK1 dimer [cytosol] (Canis familiaris)
Signal Transduction (Canis familiaris)
MAPK family signaling cascades (Canis familiaris)
MAPK6/MAPK4 signaling (Canis familiaris)
Activation of PAKs by RAC1 and CDC42 (Canis familiaris)
PAK1,2,3 dimer [cytosol] (Canis familiaris)
PAK1 dimer [cytosol] (Canis familiaris)
Signaling by Receptor Tyrosine Kinases (Canis familiaris)
Signaling by VEGF (Canis familiaris)
VEGFA-VEGFR2 Pathway (Canis familiaris)
VEGFR2 mediated vascular permeability (Canis familiaris)
PAK1-3 autophosphorylates (Canis familiaris)
PAK1,2,3 dimer [cytosol] (Canis familiaris)
PAK1 dimer [cytosol] (Canis familiaris)
PAK1-3 dimer disassociates (Canis familiaris)
2 x p-VAV family:PIP3:RAC1:GTP:PAK 1-3 [plasma membrane] (Canis familiaris)
PAK1,2,3 dimer [cytosol] (Canis familiaris)
PAK1 dimer [cytosol] (Canis familiaris)
RAC1 binds PAK1-3 (Canis familiaris)
2 x p-VAV family:PIP3:RAC1:GTP:PAK 1-3 [plasma membrane] (Canis familiaris)
PAK1,2,3 dimer [cytosol] (Canis familiaris)
PAK1 dimer [cytosol] (Canis familiaris)
PAK1,2,3 dimer [cytosol] (Canis familiaris)
PAK1 dimer [cytosol] (Canis familiaris)
Signaling by Rho GTPases, Miro GTPases and RHOBTB3 (Canis familiaris)
Signaling by Rho GTPases (Canis familiaris)
RHO GTPase Effectors (Canis familiaris)
RHO GTPases activate PAKs (Canis familiaris)
NF2 binds PAK1 (Canis familiaris)
PAK1 dimer [cytosol] (Canis familiaris)
PAK1:NF2 [plasma membrane] (Canis familiaris)
PAK1 dimer [cytosol] (Canis familiaris)
RAC1 and CDC42 activate PAK1 (Canis familiaris)
PAK1 dimer [cytosol] (Canis familiaris)
RHO GTPase cycle (Canis familiaris)
CDC42 GTPase cycle (Canis familiaris)
CDC42 binds effectors at the plasma membrane (Canis familiaris)
CDC42 effectors [cytosol] (Canis familiaris)
PAK1 dimer [cytosol] (Canis familiaris)
CDC42:GTP:CDC42 effectors [plasma membrane] (Canis familiaris)
CDC42 effectors [cytosol] (Canis familiaris)
PAK1 dimer [cytosol] (Canis familiaris)
RAC1 GTPase cycle (Canis familiaris)
RAC1 binds effectors at the plasma membrane (Canis familiaris)
RAC1 effectors [cytosol] (Canis familiaris)
PAK1 dimer [cytosol] (Canis familiaris)
RAC1:GTP:RAC1 effectors [plasma membrane] (Canis familiaris)
RAC1 effectors [cytosol] (Canis familiaris)
PAK1 dimer [cytosol] (Canis familiaris)
RAC2 GTPase cycle (Canis familiaris)
RAC2 binds effectors at the plasma membrane (Canis familiaris)
RAC2 plasma membrane effectors [cytosol] (Canis familiaris)
PAK1 dimer [cytosol] (Canis familiaris)
RAC2:GTP:RAC2 cytosolic effectors [plasma membrane] (Canis familiaris)
RAC2 plasma membrane effectors [cytosol] (Canis familiaris)
PAK1 dimer [cytosol] (Canis familiaris)
RAC3 GTPase cycle (Canis familiaris)
RAC3 binds effectors at the plasma membrane (Canis familiaris)
RAC3 effectors [cytosol] (Canis familiaris)
PAK1 dimer [cytosol] (Canis familiaris)
RAC3:GTP:RAC3 effectors [plasma membrane] (Canis familiaris)
RAC3 effectors [cytosol] (Canis familiaris)
PAK1 dimer [cytosol] (Canis familiaris)
RHOH GTPase cycle (Canis familiaris)
RHOH binds effectors at the plasma membrane (Canis familiaris)
RHOH effectors [cytosol] (Canis familiaris)
PAK1 dimer [cytosol] (Canis familiaris)
RHOH:GTP:RHOH effectors [plasma membrane] (Canis familiaris)
RHOH effectors [cytosol] (Canis familiaris)
PAK1 dimer [cytosol] (Canis familiaris)
RHOQ GTPase cycle (Canis familiaris)
RHOQ binds effectors at the plasma membrane (Canis familiaris)
RHOQ effectors [cytosol] (Canis familiaris)
PAK1 dimer [cytosol] (Canis familiaris)
RHOQ:GTP:RHOQ effectors [plasma membrane] (Canis familiaris)
RHOQ effectors [cytosol] (Canis familiaris)
PAK1 dimer [cytosol] (Canis familiaris)
RHOU GTPase cycle (Canis familiaris)
RHOU binds effectors at the plasma membrane (Canis familiaris)
RHOU effectors [cytosol] (Canis familiaris)
PAK1 dimer [cytosol] (Canis familiaris)
RHOU:GTP:RHOU effectors [plasma membrane] (Canis familiaris)
RHOU effectors [cytosol] (Canis familiaris)
PAK1 dimer [cytosol] (Canis familiaris)
RHOV GTPase cycle (Canis familiaris)
RHOV binds effectors at the plasma membrane (Canis familiaris)
RHOV effectors [cytosol] (Canis familiaris)
PAK1 dimer [cytosol] (Canis familiaris)
RHOV:GTP:RHOV effectors [plasma membrane] (Canis familiaris)
RHOV effectors [cytosol] (Canis familiaris)
PAK1 dimer [cytosol] (Canis familiaris)
General
This complex/polymer has been computationally inferred (based on PANTHER) from a complex/polymer involved in an event that has been demonstrated in another species.
Participants
components
x 2
PAK1 [cytosol]
(Canis familiaris)
Participates
as a member of
RHOV effectors [cytosol] (Canis familiaris)
RHOQ effectors [cytosol] (Canis familiaris)
RHOH effectors [cytosol] (Canis familiaris)
CDC42 effectors [cytosol] (Canis familiaris)
RAC2 plasma membrane effectors [cytosol] (Canis familiaris)
RAC1 effectors [cytosol] (Canis familiaris)
RHOJ effectors [cytosol] (Canis familiaris)
RHOU effectors [cytosol] (Canis familiaris)
PAK1,2,3 dimer [cytosol] (Canis familiaris)
PAK dimer [cytosol] (Canis familiaris)
as a candidate of
RAC3 effectors [cytosol] (Canis familiaris)
as an input of
PAK1 binds RAC1:GTP (Canis familiaris)
Interaction of PAK1 with Rac1-GTP (Canis familiaris)
NF2 binds PAK1 (Canis familiaris)
RAC1 and CDC42 activate PAK1 (Canis familiaris)
as a component of
PAK1:NF2 [plasma membrane] (Canis familiaris)
Inferred From
PAK1 dimer [cytosol]
(Homo sapiens)
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