Reactome | UTS2B [extracellular region]

UTS2B [extracellular region]

Stable Identifier

R-CFA-445100

Type

Protein [EntityWithAccessionedSequence]

Species

Canis familiaris

Compartment

extracellular region

Synonyms

UTS2B, A0A8I3S4W4

Locations in the PathwayBrowser

Expand all

Signal Transduction (Canis familiaris)

- Signaling by GPCR (Canis familiaris)
  - GPCR downstream signalling (Canis familiaris)
    - G alpha (q) signalling events (Canis familiaris)
      - Liganded Gq-activating GPCRs bind inactive heterotrimeric Gq (Canis familiaris)
        
        Ligand:GPCR complexes that activate Gq/11 [plasma membrane] (Canis familiaris)
        
        UTSR:UTS2,UTS2B [plasma membrane] (Canis familiaris)
        
        UTS2,UTS2B [extracellular region] (Canis familiaris)
        
        UTS2B [extracellular region] (Canis familiaris)
        
        Ligand:GPCR complexes that activate Gq/11:Heterotrimeric G-protein Gq (inactive) [plasma membrane] (Canis familiaris)
        
        Ligand:GPCR complexes that activate Gq/11 [plasma membrane] (Canis familiaris)
        
        UTSR:UTS2,UTS2B [plasma membrane] (Canis familiaris)
        
        UTS2,UTS2B [extracellular region] (Canis familiaris)
        
        UTS2B [extracellular region] (Canis familiaris)
      - Liganded Gq/11-activating GPCRs act as GEFs for Gq/11 (Canis familiaris)
        
        Ligand:GPCR complexes that activate Gq/11:Heterotrimeric G-protein Gq (active) [plasma membrane] (Canis familiaris)
        
        Ligand:GPCR complexes that activate Gq/11 [plasma membrane] (Canis familiaris)
        
        UTSR:UTS2,UTS2B [plasma membrane] (Canis familiaris)
        
        UTS2,UTS2B [extracellular region] (Canis familiaris)
        
        UTS2B [extracellular region] (Canis familiaris)
        
        Ligand:GPCR complexes that activate Gq/11:Heterotrimeric G-protein Gq (inactive) [plasma membrane] (Canis familiaris)
        
        Ligand:GPCR complexes that activate Gq/11 [plasma membrane] (Canis familiaris)
        
        UTSR:UTS2,UTS2B [plasma membrane] (Canis familiaris)
        
        UTS2,UTS2B [extracellular region] (Canis familiaris)
        
        UTS2B [extracellular region] (Canis familiaris)
      - The Ligand:GPCR:Gq complex dissociates (Canis familiaris)
        
        Ligand:GPCR complexes that activate Gq/11:Heterotrimeric G-protein Gq (active) [plasma membrane] (Canis familiaris)
        
        Ligand:GPCR complexes that activate Gq/11 [plasma membrane] (Canis familiaris)
        
        UTSR:UTS2,UTS2B [plasma membrane] (Canis familiaris)
        
        UTS2,UTS2B [extracellular region] (Canis familiaris)
        
        UTS2B [extracellular region] (Canis familiaris)
        
        Ligands of GPCRs that activate Gq/11 [extracellular region] (Canis familiaris)
        
        UTS2,UTS2B [extracellular region] (Canis familiaris)
        
        UTS2B [extracellular region] (Canis familiaris)
  - GPCR ligand binding (Canis familiaris)
    - Class A/1 (Rhodopsin-like receptors) (Canis familiaris)
      - Peptide ligand-binding receptors (Canis familiaris)
        
        Urotensin-2 receptor binds urotensin-2 and 2B (Canis familiaris)
        
        UTS2,UTS2B [extracellular region] (Canis familiaris)
        
        UTS2B [extracellular region] (Canis familiaris)
        
        UTSR:UTS2,UTS2B [plasma membrane] (Canis familiaris)
        
        UTS2,UTS2B [extracellular region] (Canis familiaris)
        
        UTS2B [extracellular region] (Canis familiaris)

External Reference Information

External Reference

UniProt:A0A8I3S4W4

Gene Names

UTS2B

Reference Genes

BioGPS Gene:608290 UTS2B

ENSEMBL:ENSCAFG00845024789.1

ENSEMBL_canis_lupus_familiaris_GENE:ENSCAFG00845024789.1 UTS2B

Monarch:608290 UTS2B

NCBI Gene:608290 UTS2B

Reference Transcript

RefSeq:XM_845265.4 UTS2B

Other Identifiers

608290

CfaAffx.21674.1.S1_at

GO:0003013

GO:0005179

GO:0005576

GO:0007165

GO:0008217

GO:0023052

GO:0048018

GO:0097746

GO:0098772

Participates

as a member of

UTS2,UTS2B [extracellular region] (Canis familiaris)

Inferred From

UTS2B [extracellular region] (Homo sapiens)

Cross References

RefSeq

XP_850358.2

OpenTargets

ENSG00000188958

Ensembl

ENSCAFP00845034273, ENSCAFT00845043740, ENSCAFG00845024789