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CAV1 [plasma membrane]
Stable Identifier
R-CFA-534994
Type
Protein [EntityWithAccessionedSequence]
Species
Canis familiaris
Compartment
plasma membrane
Synonyms
CAV1, P33724
Locations in the PathwayBrowser
Expand all
Metabolism (Canis familiaris)
Metabolism of nitric oxide: NOS3 activation and regulation (Canis familiaris)
NOSTRIN mediated eNOS trafficking (Canis familiaris)
NOSTRIN mediated translocation of eNOS from plasma membrane (Canis familiaris)
eNOS:Caveolin-1:NOSTRIN:dynamin-2:N-WASP [plasma membrane] (Canis familiaris)
CAV1 [plasma membrane] (Canis familiaris)
eNOS:Caveolin-1:NOSTRIN:dynamin-2 complex binds N-WASP (Canis familiaris)
eNOS:Caveolin-1:NOSTRIN:Dynamin-2 [plasma membrane] (Canis familiaris)
CAV1 [plasma membrane] (Canis familiaris)
eNOS:Caveolin-1:NOSTRIN:dynamin-2:N-WASP [plasma membrane] (Canis familiaris)
CAV1 [plasma membrane] (Canis familiaris)
Signal Transduction (Canis familiaris)
Signaling by Nuclear Receptors (Canis familiaris)
ESR-mediated signaling (Canis familiaris)
Extra-nuclear estrogen signaling (Canis familiaris)
PalmS-ESRs:CAVs translocate to plasma membrane (Canis familiaris)
CAVs [plasma membrane] (Canis familiaris)
CAV1 [plasma membrane] (Canis familiaris)
Signaling by Rho GTPases, Miro GTPases and RHOBTB3 (Canis familiaris)
Signaling by Rho GTPases (Canis familiaris)
RHO GTPase cycle (Canis familiaris)
CDC42 GTPase cycle (Canis familiaris)
CDC42 GDIs block activation of CDC42 (Canis familiaris)
CDC42 GDIs [cytosol] (Canis familiaris)
CAV1 [plasma membrane] (Canis familiaris)
CDC42:GDP:CDC42 GDIs [cytosol] (Canis familiaris)
CDC42 GDIs [cytosol] (Canis familiaris)
CAV1 [plasma membrane] (Canis familiaris)
CDC42 binds effectors at the plasma membrane (Canis familiaris)
CDC42 effectors [cytosol] (Canis familiaris)
CAV1 [plasma membrane] (Canis familiaris)
CDC42:GTP:CDC42 effectors [plasma membrane] (Canis familiaris)
CDC42 effectors [cytosol] (Canis familiaris)
CAV1 [plasma membrane] (Canis familiaris)
RAC1 GTPase cycle (Canis familiaris)
RAC1 binds effectors at the plasma membrane (Canis familiaris)
RAC1 effectors [cytosol] (Canis familiaris)
CAV1 [plasma membrane] (Canis familiaris)
RAC1:GTP:RAC1 effectors [plasma membrane] (Canis familiaris)
RAC1 effectors [cytosol] (Canis familiaris)
CAV1 [plasma membrane] (Canis familiaris)
RAC2 GTPase cycle (Canis familiaris)
RAC2 binds effectors at the plasma membrane (Canis familiaris)
RAC2 plasma membrane effectors [cytosol] (Canis familiaris)
CAV1 [plasma membrane] (Canis familiaris)
RAC2:GTP:RAC2 cytosolic effectors [plasma membrane] (Canis familiaris)
RAC2 plasma membrane effectors [cytosol] (Canis familiaris)
CAV1 [plasma membrane] (Canis familiaris)
RAC3 GTPase cycle (Canis familiaris)
RAC3 binds effectors at the plasma membrane (Canis familiaris)
RAC3 effectors [cytosol] (Canis familiaris)
CAV1 [plasma membrane] (Canis familiaris)
RAC3:GTP:RAC3 effectors [plasma membrane] (Canis familiaris)
RAC3 effectors [cytosol] (Canis familiaris)
CAV1 [plasma membrane] (Canis familiaris)
RHOA GTPase cycle (Canis familiaris)
RHOA binds effectors at the plasma membrane (Canis familiaris)
RHOA plasma membrane effectors [cytosol] (Canis familiaris)
CAV1 [plasma membrane] (Canis familiaris)
RHOA:GTP:cytosolic RHOA effectors [plasma membrane] (Canis familiaris)
RHOA plasma membrane effectors [cytosol] (Canis familiaris)
CAV1 [plasma membrane] (Canis familiaris)
RHOB GTPase cycle (Canis familiaris)
RHOB binds effectors at the plasma membrane (Canis familiaris)
RHOB effectors (plasma membrane) [cytosol] (Canis familiaris)
CAV1 [plasma membrane] (Canis familiaris)
RHOB:GTP:cytosolic RHOB effectors [plasma membrane] (Canis familiaris)
RHOB effectors (plasma membrane) [cytosol] (Canis familiaris)
CAV1 [plasma membrane] (Canis familiaris)
RHOC GTPase cycle (Canis familiaris)
RHOC binds effectors at the plasma membrane (Canis familiaris)
RHOC effectors [cytosol] (Canis familiaris)
CAV1 [plasma membrane] (Canis familiaris)
RHOC:GTP:RHOC effectors [plasma membrane] (Canis familiaris)
RHOC effectors [cytosol] (Canis familiaris)
CAV1 [plasma membrane] (Canis familiaris)
RHOD GTPase cycle (Canis familiaris)
RHOD binds effectors at the plasma membrane (Canis familiaris)
RHOD plasma membrane effectors [cytosol] (Canis familiaris)
CAV1 [plasma membrane] (Canis familiaris)
RHOD:GTP:RHOD plasma membrane effectors [plasma membrane] (Canis familiaris)
RHOD plasma membrane effectors [cytosol] (Canis familiaris)
CAV1 [plasma membrane] (Canis familiaris)
RHOF GTPase cycle (Canis familiaris)
RHOF binds effectors at the plasma membrane (Canis familiaris)
RHOF effectors [cytosol] (Canis familiaris)
CAV1 [plasma membrane] (Canis familiaris)
RHOF:GTP:RHOF effectors [plasma membrane] (Canis familiaris)
RHOF effectors [cytosol] (Canis familiaris)
CAV1 [plasma membrane] (Canis familiaris)
RHOG GTPase cycle (Canis familiaris)
RHOG binds effectors at the plasma membrane (Canis familiaris)
RHOG plasma membrane effectors [cytosol] (Canis familiaris)
CAV1 [plasma membrane] (Canis familiaris)
RHOG:GTP:RHOG plasma membrane effectors [plasma membrane] (Canis familiaris)
RHOG plasma membrane effectors [cytosol] (Canis familiaris)
CAV1 [plasma membrane] (Canis familiaris)
RHOH GTPase cycle (Canis familiaris)
RHOH binds effectors at the plasma membrane (Canis familiaris)
RHOH effectors [cytosol] (Canis familiaris)
CAV1 [plasma membrane] (Canis familiaris)
RHOH:GTP:RHOH effectors [plasma membrane] (Canis familiaris)
RHOH effectors [cytosol] (Canis familiaris)
CAV1 [plasma membrane] (Canis familiaris)
RHOQ GTPase cycle (Canis familiaris)
RHOQ binds effectors at the plasma membrane (Canis familiaris)
RHOQ effectors [cytosol] (Canis familiaris)
CAV1 [plasma membrane] (Canis familiaris)
RHOQ:GTP:RHOQ effectors [plasma membrane] (Canis familiaris)
RHOQ effectors [cytosol] (Canis familiaris)
CAV1 [plasma membrane] (Canis familiaris)
RND1 GTPase cycle (Canis familiaris)
RND1 binds effectors (Canis familiaris)
RND1 effectors [cytosol] (Canis familiaris)
CAV1 [plasma membrane] (Canis familiaris)
RND1:GTP:RND1 effectors [plasma membrane] (Canis familiaris)
RND1 effectors [cytosol] (Canis familiaris)
CAV1 [plasma membrane] (Canis familiaris)
RND2 GTPase cycle (Canis familiaris)
RND2 binds effectors (Canis familiaris)
RND2 effectors [cytosol] (Canis familiaris)
CAV1 [plasma membrane] (Canis familiaris)
RND2:GTP:RND2 effectors [plasma membrane] (Canis familiaris)
RND2 effectors [cytosol] (Canis familiaris)
CAV1 [plasma membrane] (Canis familiaris)
RND3 GTPase cycle (Canis familiaris)
RND3 binds effectors (Canis familiaris)
RND3 effectors [cytosol] (Canis familiaris)
CAV1 [plasma membrane] (Canis familiaris)
RND3:GTP:RND3 effectors [plasma membrane] (Canis familiaris)
RND3 effectors [cytosol] (Canis familiaris)
CAV1 [plasma membrane] (Canis familiaris)
Signaling by WNT (Canis familiaris)
TCF dependent signaling in response to WNT (Canis familiaris)
Disassembly of the destruction complex and recruitment of AXIN to the membrane (Canis familiaris)
WNT3A stimulates the caveolin-dependent internalization of FZD5:p-LRP6 (Canis familiaris)
WNT3A:FZD5:p-LRP6:GSK3B:AXIN:CAV1 [plasma membrane] (Canis familiaris)
CAV1 [plasma membrane] (Canis familiaris)
External Reference Information
External Reference
UniProt:P33724
Gene Names
CAV1
Reference Genes
BioGPS Gene:403980 CAV1
ENSEMBL:ENSCAFG00040016536
ENSEMBL_canis_lupus_familiaris_GENE:ENSCAFG00000055058.1 CAV1
ENSEMBL_canis_lupus_familiaris_GENE:ENSCAFG00030007606.1 CAV1
ENSEMBL_canis_lupus_familiaris_GENE:ENSCAFG00040016536.1 CAV1
ENSEMBL_canis_lupus_familiaris_GENE:ENSCAFG00805005756 CAV1
ENSEMBL_canis_lupus_familiaris_GENE:ENSCAFG00845006847.1 CAV1
KEGG Gene (Canis lupus familiaris):403980 CAV1
Monarch:403980 CAV1
NCBI Gene:403980 CAV1
Reference Transcript
RefSeq:XM_014118875.1 CAV1
RefSeq:XM_005628347.2 CAV1
RefSeq:NM_001003296.1 CAV1
Other Identifiers
403980
Cfa.1193.1.S1_at
Cfa.3850.1.S1_s_at
Cfa.3850.1.S2_at
GO:0000122
GO:0000139
GO:0000165
GO:0001525
GO:0001570
GO:0001666
GO:0001935
GO:0001937
GO:0001960
GO:0002026
GO:0002067
GO:0002080
GO:0002095
GO:0002376
GO:0002931
GO:0003012
GO:0003013
GO:0003057
GO:0005102
GO:0005768
GO:0005783
GO:0005794
GO:0005886
GO:0005901
GO:0005925
GO:0005929
GO:0005938
GO:0006351
GO:0006355
GO:0006629
GO:0006641
GO:0006809
GO:0006816
GO:0006874
GO:0006940
GO:0007155
GO:0007519
GO:0007595
GO:0008104
GO:0008283
GO:0008285
GO:0009617
GO:0009968
GO:0010524
GO:0010608
GO:0010628
GO:0010875
GO:0012501
GO:0015031
GO:0016020
GO:0016192
GO:0016504
GO:0019065
GO:0019217
GO:0019221
GO:0019899
GO:0019901
GO:0019915
GO:0023052
GO:0030154
GO:0030163
GO:0030193
GO:0030198
GO:0030292
GO:0030335
GO:0030674
GO:0030857
GO:0030879
GO:0031267
GO:0031295
GO:0031397
GO:0031398
GO:0031410
GO:0031623
GO:0032570
GO:0032991
GO:0033137
GO:0033138
GO:0033484
GO:0034141
GO:0034330
GO:0036211
GO:0038016
GO:0038166
GO:0042060
GO:0042310
GO:0042532
GO:0042632
GO:0042802
GO:0043123
GO:0043226
GO:0043409
GO:0043627
GO:0044325
GO:0044877
GO:0045019
GO:0045121
GO:0045907
GO:0046426
GO:0046716
GO:0046982
GO:0048144
GO:0048147
GO:0048471
GO:0048550
GO:0048856
GO:0048870
GO:0050998
GO:0051117
GO:0051480
GO:0051592
GO:0051649
GO:0051899
GO:0055065
GO:0055074
GO:0055085
GO:0060056
GO:0060090
GO:0060355
GO:0060546
GO:0061024
GO:0070320
GO:0070836
GO:0071360
GO:0071375
GO:0071455
GO:0071560
GO:0071711
GO:0072584
GO:0086091
GO:0090090
GO:0090263
GO:0097190
GO:0098542
GO:0098772
GO:0098903
GO:0098911
GO:0120162
GO:1900027
GO:1900085
GO:1901380
GO:1901844
GO:1903071
GO:1903598
GO:2000286
GO:2000535
GO:2000811
GO:2001238
GO:2001244
Participates
as a candidate of
RND2 effectors [cytosol] (Canis familiaris)
RHOA plasma membrane effectors [cytosol] (Canis familiaris)
RND3 effectors [cytosol] (Canis familiaris)
RHOC effectors [cytosol] (Canis familiaris)
RHOQ effectors [cytosol] (Canis familiaris)
RHOH effectors [cytosol] (Canis familiaris)
CDC42 effectors [cytosol] (Canis familiaris)
RAC2 plasma membrane effectors [cytosol] (Canis familiaris)
RHOD plasma membrane effectors [cytosol] (Canis familiaris)
RHOF effectors [cytosol] (Canis familiaris)
RHOB effectors (plasma membrane) [cytosol] (Canis familiaris)
RHOG plasma membrane effectors [cytosol] (Canis familiaris)
RHOJ effectors [cytosol] (Canis familiaris)
RAC3 effectors [cytosol] (Canis familiaris)
RND1 effectors [cytosol] (Canis familiaris)
as a member of
CDC42 GDIs [cytosol] (Canis familiaris)
RAC1 effectors [cytosol] (Canis familiaris)
CAVs [plasma membrane] (Canis familiaris)
as a component of
eNOS:Caveolin-1:NOSTRIN:Dynamin-2 [plasma membrane] (Canis familiaris)
eNOS:Caveolin-1:NOSTRIN:dynamin-2:N-WASP [plasma membrane] (Canis familiaris)
eNOS:Caveolin-1 [plasma membrane] (Canis familiaris)
WNT3A:FZD5:p-LRP6:GSK3B:AXIN:CAV1 [plasma membrane] (Canis familiaris)
Other forms of this molecule
CAV1 [endocytic vesicle membrane]
CAV1 [lipid droplet]
CAV1 [early endosome membrane]
CAV1 [Golgi membrane]
Inferred From
CAV1 [plasma membrane]
(Homo sapiens)
Cross References
RefSeq
XP_005628404.1
,
XP_013974350.1
,
NP_001003296.1
OpenTargets
ENSG00000105974
Ensembl
ENSCAFP00845009515
,
ENSCAFG00845006847
,
ENSCAFT00845012174
VGNC
38751
Interactors (4)
Accession
#Entities
Entities
Confidence Score
Evidence (IntAct)
UniProt:P35222 CTNNB1
20
CTNNB1 S45A [cytosol]
(R-HSA-9663982)
CTNNB1 S45F [cytosol]
(R-HSA-4791268)
CTNNB1 S45C [cytosol]
(R-HSA-9663983)
CTNNB1 S45Y [cytosol]
(R-HSA-9663975)
CTNNB1 S45N [cytosol]
(R-HSA-9663984)
CTNNB1 S45P [cytosol]
(R-HSA-4791272)
pT41,S45-CTNNB1 S37P [cytosol]
(R-HSA-9663981)
pT41,S45-CTNNB1 S37F [cytosol]
(R-HSA-4839621)
pT41,S45-CTNNB1 S37A [cytosol]
(R-HSA-4839619)
pT41,S45-CTNNB1 S37Y [cytosol]
(R-HSA-9663978)
pT41,S45-CTNNB1 S37C [cytosol]
(R-HSA-4839617)
pS37,T41,S45-CTNNB1 S33A [cytosol]
(R-HSA-9663976)
pS37,T41,S45-CTNNB1 S33T [cytosol]
(R-HSA-9663977)
pS37,T41,S45-CTNNB1 S33C [cytosol]
(R-HSA-4839630)
pS37,T41,S45-CTNNB1 S33F [cytosol]
(R-HSA-4839628)
pS37,T41,S45-CTNNB1 S33P [cytosol]
(R-HSA-4839626)
pS37,T41,S45-CTNNB1 S33Y [cytosol]
(R-HSA-4839625)
pS45-CTNNB1 T41N [cytosol]
(R-HSA-9663980)
pS45-CTNNB1 T41A [cytosol]
(R-HSA-4836868)
pS45-CTNNB1 T41I [cytosol]
(R-HSA-4839612)
0.571
5
UniProt:P12830 CDH1
8
CDH1(732-882) [plasma membrane]
(R-HSA-3827997)
CDH1(155-700) [plasma membrane]
(R-HSA-2534244)
CDH1(701-882) [extracellular region]
(R-HSA-2534158)
Ub-K,p-Y753,Y754-CDH1(155-882) [plasma membrane]
(R-HSA-8877002)
p-Y753,Y754-CDH1(155-882) [plasma membrane]
(R-HSA-8876938)
CDH1(155-750) [plasma membrane]
(R-HSA-202940)
CDH1(751-882) [plasma membrane]
(R-HSA-202929)
CDH1(155-882) [plasma membrane]
(R-HSA-198003)
0.525
2
UniProt:P59632 3a
10
O-glycosyl 3a [lysosomal membrane]
(R-COV-9692650)
O-glycosyl 3a [cytosol]
(R-COV-9686279)
O-glycosyl 3a [extracellular region]
(R-COV-9685941)
O-glycosyl 3a [plasma membrane]
(R-COV-9685962)
3a [endoplasmic reticulum lumen]
(R-COV-9683715)
3a [endoplasmic reticulum-Golgi intermediate compartment]
(R-COV-9683691)
GalNAc-O-3a [endoplasmic reticulum-Golgi intermediate compartment]
(R-COV-9683709)
O-glycosyl 3a [endoplasmic reticulum-Golgi intermediate compartment membrane]
(R-COV-9683640)
O-glycosyl 3a [endocytic vesicle membrane]
(R-COV-9686708)
O-glycosyl 3a [virion membrane]
(R-COV-9686228)
0.505
5
UniProt:B6V8E6 CTNB1
0.463
2
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