Reactome | MRPS18B [mitochondrial inner membrane]

MRPS18B [mitochondrial inner membrane]

Stable Identifier

R-CFA-5368234

Type

Protein [EntityWithAccessionedSequence]

Species

Canis familiaris

Compartment

mitochondrial inner membrane

Synonyms

MRPS18B, A0A8I3N171

Locations in the PathwayBrowser

Expand all

Metabolism of proteins (Canis familiaris)

- Translation (Canis familiaris)
  - Mitochondrial translation (Canis familiaris)
    - Mitochondrial translation elongation (Canis familiaris)
      - 55S ribosome with peptidyl-tRNA in A site binds GFM1:GTP (Canis familiaris)
        
        55S ribosome:mRNA:tRNA:peptidyl-tRNA at A-site [mitochondrial inner membrane] (Canis familiaris)
        
        55S ribosome [mitochondrial inner membrane] (Canis familiaris)
        
        28S ribosomal subunit [mitochondrial inner membrane] (Canis familiaris)
        
        MRPS18A,B,C [mitochondrial inner membrane] (Canis familiaris)
        
        MRPS18B [mitochondrial inner membrane] (Canis familiaris)
        
        55S ribosome:mRNA:tRNA:peptidyl-tRNA:GFM1:GTP [mitochondrial inner membrane] (Canis familiaris)
        
        55S ribosome [mitochondrial inner membrane] (Canis familiaris)
        
        28S ribosomal subunit [mitochondrial inner membrane] (Canis familiaris)
        
        MRPS18A,B,C [mitochondrial inner membrane] (Canis familiaris)
        
        MRPS18B [mitochondrial inner membrane] (Canis familiaris)
    - Mitochondrial translation termination (Canis familiaris)
      - 55S ribosome hydrolyzes peptidyl-tRNA bond and MTRF1L hydrolyzes GTP (Canis familiaris)
        
        55S ribosome:mRNA:peptidyl-tRNA:MTRF1L:GTP [mitochondrial inner membrane] (Canis familiaris)
        
        55S ribosome [mitochondrial inner membrane] (Canis familiaris)
        
        28S ribosomal subunit [mitochondrial inner membrane] (Canis familiaris)
        
        MRPS18A,B,C [mitochondrial inner membrane] (Canis familiaris)
        
        MRPS18B [mitochondrial inner membrane] (Canis familiaris)
        
        55S ribosome:mRNA:tRNA [mitochondrial inner membrane] (Canis familiaris)
        
        55S ribosome [mitochondrial inner membrane] (Canis familiaris)
        
        28S ribosomal subunit [mitochondrial inner membrane] (Canis familiaris)
        
        MRPS18A,B,C [mitochondrial inner membrane] (Canis familiaris)
        
        MRPS18B [mitochondrial inner membrane] (Canis familiaris)
      - Hydrolysis of GTP and dissociation of 28S and 39S subunits (Canis familiaris)
        
        28S ribosomal subunit [mitochondrial inner membrane] (Canis familiaris)
        
        MRPS18A,B,C [mitochondrial inner membrane] (Canis familiaris)
        
        MRPS18B [mitochondrial inner membrane] (Canis familiaris)
        
        55S ribosome:MRRF:GFM2:GTP [mitochondrial inner membrane] (Canis familiaris)
        
        55S ribosome [mitochondrial inner membrane] (Canis familiaris)
        
        28S ribosomal subunit [mitochondrial inner membrane] (Canis familiaris)
        
        MRPS18A,B,C [mitochondrial inner membrane] (Canis familiaris)
        
        MRPS18B [mitochondrial inner membrane] (Canis familiaris)
      - MRRF binds 55S ribosome:mRNA:tRNA (Canis familiaris)
        
        55S ribosome:mRNA:tRNA [mitochondrial inner membrane] (Canis familiaris)
        
        55S ribosome [mitochondrial inner membrane] (Canis familiaris)
        
        28S ribosomal subunit [mitochondrial inner membrane] (Canis familiaris)
        
        MRPS18A,B,C [mitochondrial inner membrane] (Canis familiaris)
        
        MRPS18B [mitochondrial inner membrane] (Canis familiaris)
        
        55S ribosome:mRNA:tRNA:MRRF [mitochondrial inner membrane] (Canis familiaris)
        
        55S ribosome [mitochondrial inner membrane] (Canis familiaris)
        
        28S ribosomal subunit [mitochondrial inner membrane] (Canis familiaris)
        
        MRPS18A,B,C [mitochondrial inner membrane] (Canis familiaris)
        
        MRPS18B [mitochondrial inner membrane] (Canis familiaris)
      - MTRF1L (MTRF1a) or ICT1 binds stop codon in 55S ribosome:mRNA:peptidyl-tRNA (Canis familiaris)
        
        55S ribosome:mRNA:peptidyl-tRNA at P-site [mitochondrial inner membrane] (Canis familiaris)
        
        55S ribosome [mitochondrial inner membrane] (Canis familiaris)
        
        28S ribosomal subunit [mitochondrial inner membrane] (Canis familiaris)
        
        MRPS18A,B,C [mitochondrial inner membrane] (Canis familiaris)
        
        MRPS18B [mitochondrial inner membrane] (Canis familiaris)
        
        55S ribosome:mRNA:peptidyl-tRNA:MTRF1L:GTP [mitochondrial inner membrane] (Canis familiaris)
        
        55S ribosome [mitochondrial inner membrane] (Canis familiaris)
        
        28S ribosomal subunit [mitochondrial inner membrane] (Canis familiaris)
        
        MRPS18A,B,C [mitochondrial inner membrane] (Canis familiaris)
        
        MRPS18B [mitochondrial inner membrane] (Canis familiaris)

External Reference Information

External Reference

UniProt:A0A8I3N171

Gene Names

MRPS18B

Reference Genes

BioGPS Gene:474827 MRPS18B

ENSEMBL:ENSCAFG00845007249.1

ENSEMBL_canis_lupus_familiaris_GENE:ENSCAFG00845007249.1 MRPS18B

KEGG Gene (Canis lupus familiaris):474827 MRPS18B

Monarch:474827 MRPS18B

NCBI Gene:474827 MRPS18B

Reference Transcript

RefSeq:XM_532057.5 MRPS18B

Other Identifiers

474827

Cfa.5613.1.A1_at

CfaAffx.1572.1.S1_at

CfaAffx.1572.1.S1_s_at

GO:0003735

GO:0005198

GO:0005634

GO:0005654

GO:0005739

GO:0005763

GO:0005840

GO:0006412

GO:0030054

GO:0032543

GO:0043226

GO:0140053

GO:1990904

Participates

as a member of

MRPS18A,B,C [mitochondrial inner membrane] (Canis familiaris)

Inferred From

MRPS18B [mitochondrial inner membrane] (Homo sapiens)

Cross References

RefSeq

XP_532057.2

OpenTargets

ENSG00000204568

Ensembl

ENSCAFP00845009996, ENSCAFG00845007249, ENSCAFT00845012826

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