Reactome | phospho-H3C13 [nucleoplasm]

phospho-H3C13 [nucleoplasm]

Stable Identifier

R-CFA-5625871

Type

Protein [EntityWithAccessionedSequence]

Species

Canis familiaris

Compartment

nucleoplasm

Synonyms

p-T12-HIST2H3A, J9P7X1

Locations in the PathwayBrowser

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Signal Transduction (Canis familiaris)

- Signaling by Rho GTPases (Canis familiaris)
  - RHO GTPase Effectors (Canis familiaris)
    - RHO GTPases activate PKNs (Canis familiaris)
      - Activated PKN1 stimulates transcription of AR (androgen receptor) regulated genes KLK2 and KLK3 (Canis familiaris)
        
        KDM1A demethylates monomethylated H3K9 (MeK-10-H3) at KLK2 and KLK3 promoters (Canis familiaris)
        
        p-T774-PKN1:AR:Androgen:KLK2,3 Gene:Nucleosome with p-T12-H3 [nucleoplasm] (Canis familiaris)
        
        Nucleosome with p-T12-H3 [nucleoplasm] (Canis familiaris)
        
        p-T12-H3 [nucleoplasm] (Canis familiaris)
        
        phospho-H3C13 [nucleoplasm] (Canis familiaris)

External Reference Information

External Reference

UniProt:J9P7X1

Gene Names

H3C13

Reference Genes

BioGPS Gene:483172 H3C13

ENSEMBL:ENSCAFG00000024443

ENSEMBL_canis_lupus_familiaris_GENE:ENSCAFG00000024443 H3C13

ENSEMBL_canis_lupus_familiaris_GENE:ENSCAFG00000041871 H3C13

KEGG Gene (Canis familiaris):483172 H3C13

Monarch:483172 H3C13

NCBI Gene:483172 H3C13

Reference Transcript

Other Identifiers

111090006

483172

CfaAffx.17935.1.S1_s_at

CfaAffx.945.1.S1_s_at

GO:0000786

GO:0003674

GO:0003677

GO:0005575

GO:0005622

GO:0005694

GO:0032991

GO:0043226

GO:0046982

Participant Of

hasMember

p-T12-H3 [nucleoplasm]

Other forms of this molecule

H3C13 [nucleoplasm]

phospho-H3C13 [nucleoplasm]

H3C13 [nucleoplasm]

H3C13 [cytosol]

H3C13 [nucleoplasm]

phospho-H3C13 [nucleoplasm]

H3C13 [nucleoplasm]

phospho-H3C13 [nucleoplasm]

H3C13 [nucleoplasm]

Inferred From

p-T12-HIST2H3A [nucleoplasm] (Homo sapiens)

Modified Residues

Name

O-phospho-L-threonine at 12 (in Homo sapiens)

Coordinate

PsiMod Name

O-phospho-L-threonine [MOD:00047]

PsiMod Definition

A protein modification that effectively converts an L-threonine residue to O-phospho-L-threonine.

Cross References

RefSeq

XP_013976105.1, XP_540290.2

OpenTargets

ENSG00000183598

Ensembl

ENSCAFP00000041760, ENSCAFG00000024443, ENSCAFT00000077488, ENSCAFT00000037742, ENSCAFG00000041871, ENSCAFP00000054547

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