Toggle navigation
About
What is Reactome ?
News
Team
Scientific Advisory Board
Editorial Calendar
Release Calendar
Statistics
Our Logo
License Agreement
Privacy Notice
Disclaimer
Digital Preservation
Contact us
Content
Table of Contents
DOIs
Data Schema
Reactome Research Spotlight
ORCID Integration Project
COVID-19 Disease Pathways
Docs
Userguide
Pathway Browser
How do I search ?
Details Panel
Analysis Tools
Analysis Data
Analysis Gene Expression
Species Comparison
Tissue Distribution
Diseases
Cytomics
Review Status of Reactome Events
ReactomeFIViz
Developer's Zone
Graph Database
Analysis Service
Content Service
Pathways Overview
Pathway Diagrams
Icon Info
EHLD Specs & Guidelines
Icon Library Guidelines
Data Model
Computationally inferred events
FAQ
Linking to Us
Citing us
Tools
Pathway Browser
Analyse gene list
Analyse gene expression
Species Comparison
Tissue Distribution
Analysis Service
Content Service
ReactomeFIViz
Overlays
DisGeNET
Web
API
Advanced Data Search
Site Search
Community
Contribute Pathway Knowledge
Icon Library
Outreach
Events
Publications
Partners
Contributors
Resources Guide
Download
About
What is Reactome ?
News
Team
Scientific Advisory Board
Editorial Calendar
Release Calendar
Statistics
Our Logo
License Agreement
Privacy Notice
Disclaimer
Digital Preservation
Contact us
Content
Table of Contents
DOIs
Data Schema
Reactome Research Spotlight
ORCID Integration Project
COVID-19 Disease Pathways
Docs
Userguide
Pathway Browser
How do I search ?
Details Panel
Analysis Tools
Analysis Data
Analysis Gene Expression
Species Comparison
Tissue Distribution
Diseases
Cytomics
Review Status of Reactome Events
ReactomeFIViz
Developer's Zone
Graph Database
Analysis Service
Content Service
Pathways Overview
Pathway Diagrams
Icon Info
EHLD Specs & Guidelines
Icon Library Guidelines
Data Model
Computationally inferred events
FAQ
Linking to Us
Citing us
Tools
Pathway Browser
Analyse gene list
Analyse gene expression
Species Comparison
Tissue Distribution
Analysis Service
Content Service
ReactomeFIViz
Overlays
DisGeNET
Web
API
Advanced Data Search
Site Search
Community
Contribute Pathway Knowledge
Icon Library
Outreach
Events
Publications
Partners
Contributors
Resources Guide
Download
Search ...
Go!
RHOA:GTP [plasma membrane]
Stable Identifier
R-CFA-5665993
Type
Complex
Species
Canis familiaris
Compartment
plasma membrane
Locations in the PathwayBrowser
Expand all
Developmental Biology (Canis familiaris)
Nervous system development (Canis familiaris)
Axon guidance (Canis familiaris)
EPH-Ephrin signaling (Canis familiaris)
EPHA-mediated growth cone collapse (Canis familiaris)
NGEF exchanges GTP for GDP on RHOA (Canis familiaris)
RHOA:GTP [plasma membrane] (Canis familiaris)
EPHB-mediated forward signaling (Canis familiaris)
RHOA:GTP binds ROCK, activating it (Canis familiaris)
RHOA:GTP [plasma membrane] (Canis familiaris)
RHOA:GTP:ROCK1,ROCK2 [plasma membrane] (Canis familiaris)
RHOA:GTP [plasma membrane] (Canis familiaris)
p190RhoGEF exchanges GTP for GDP on RHOA, activating it (Canis familiaris)
RHOA:GTP [plasma membrane] (Canis familiaris)
Semaphorin interactions (Canis familiaris)
Sema4D in semaphorin signaling (Canis familiaris)
Sema4D mediated inhibition of cell attachment and migration (Canis familiaris)
Inactivation of Rho-GTP by p190RhoGAP (Canis familiaris)
RHOA:GTP [plasma membrane] (Canis familiaris)
Signaling by ROBO receptors (Canis familiaris)
SLIT2:ROBO1 increases RHOA activity (Canis familiaris)
MYO9B inactivates RHOA (Canis familiaris)
RHOA:GTP [plasma membrane] (Canis familiaris)
Signal Transduction (Canis familiaris)
Death Receptor Signaling (Canis familiaris)
p75 NTR receptor-mediated signalling (Canis familiaris)
p75NTR regulates axonogenesis (Canis familiaris)
Axonal growth inhibition (RHOA activation) (Canis familiaris)
RhoA is activated by nucleotide exchange and inhibits axonal growth (Canis familiaris)
RHOA:GTP [plasma membrane] (Canis familiaris)
Signaling by GPCR (Canis familiaris)
GPCR downstream signalling (Canis familiaris)
G alpha (12/13) signalling events (Canis familiaris)
p115-RhoGEF activation of RHOA (Canis familiaris)
RHOA:GTP [plasma membrane] (Canis familiaris)
Signaling by Non-Receptor Tyrosine Kinases (Canis familiaris)
Signaling by PTK6 (Canis familiaris)
PTK6 Regulates RHO GTPases, RAS GTPase and MAP kinases (Canis familiaris)
ARHGAP35 binds RHOA:GTP (Canis familiaris)
RHOA:GTP [plasma membrane] (Canis familiaris)
p-Y1105-ARHGAP35:RHOA:GTP [cytosol] (Canis familiaris)
RHOA:GTP [plasma membrane] (Canis familiaris)
ARHGAP35 stimulates RHOA GTPase activity (Canis familiaris)
p-Y1105-ARHGAP35:RHOA:GTP [cytosol] (Canis familiaris)
RHOA:GTP [plasma membrane] (Canis familiaris)
Signaling by Receptor Tyrosine Kinases (Canis familiaris)
Signaling by ERBB2 (Canis familiaris)
ERBB2 Regulates Cell Motility (Canis familiaris)
MEMO1 binds RHOA:GTP:DIAPH1 (Canis familiaris)
RHOA:GTP:DIAPH1 [plasma membrane] (Canis familiaris)
RHOA:GTP [plasma membrane] (Canis familiaris)
p-ERBB2 heterodimers:MEMO1:RHOA:GTP:DIAPH1 [plasma membrane] (Canis familiaris)
RHOA:GTP:DIAPH1 [plasma membrane] (Canis familiaris)
RHOA:GTP [plasma membrane] (Canis familiaris)
Signaling by VEGF (Canis familiaris)
VEGFA-VEGFR2 Pathway (Canis familiaris)
RHOA:GTP:Mg2+ binds ROCK1,ROCK2 (Canis familiaris)
RHOA:GTP [plasma membrane] (Canis familiaris)
RHOA:GTP:ROCK1,ROCK2 [plasma membrane] (Canis familiaris)
RHOA:GTP [plasma membrane] (Canis familiaris)
ROCK1,ROCK2 are activated (Canis familiaris)
RHOA:GTP:ROCK1,ROCK2 [plasma membrane] (Canis familiaris)
RHOA:GTP [plasma membrane] (Canis familiaris)
Signaling by Rho GTPases, Miro GTPases and RHOBTB3 (Canis familiaris)
Signaling by Rho GTPases (Canis familiaris)
RHO GTPase Effectors (Canis familiaris)
RHO GTPases Activate Formins (Canis familiaris)
DIAPH1 binds RHOA:GTP (Canis familiaris)
RHOA:GTP [plasma membrane] (Canis familiaris)
RHOA:GTP:DIAPH1 [plasma membrane] (Canis familiaris)
RHOA:GTP [plasma membrane] (Canis familiaris)
RHOA:GTP:DIAPH1 binds EVL and sequesters profilin:G-actin from MKL1 (Canis familiaris)
RHOA:GTP:DIAPH1 [plasma membrane] (Canis familiaris)
RHOA:GTP [plasma membrane] (Canis familiaris)
RHOA:GTP:DIAPH1:EVL:Profilin:G-actin [plasma membrane] (Canis familiaris)
RHOA:GTP:DIAPH1 [plasma membrane] (Canis familiaris)
RHOA:GTP [plasma membrane] (Canis familiaris)
RHO GTPases Activate Rhotekin and Rhophilins (Canis familiaris)
RHOA:GTP binds RHPN1 or RHPN2 (Canis familiaris)
RHOA:GTP [plasma membrane] (Canis familiaris)
RHOA:GTP:RHPN1,RHPN2 [plasma membrane] (Canis familiaris)
RHOA:GTP [plasma membrane] (Canis familiaris)
RHOA:GTP:RTKN binds LIN7B (Canis familiaris)
RHOA:GTP:RTKN [plasma membrane] (Canis familiaris)
RHOA:GTP [plasma membrane] (Canis familiaris)
RHOA:GTP:RTKN:LIN7B [plasma membrane] (Canis familiaris)
RHOA:GTP [plasma membrane] (Canis familiaris)
RHOA:GTP:RTKN binds TAX1BP3 (Canis familiaris)
RHOA:GTP:RTKN [plasma membrane] (Canis familiaris)
RHOA:GTP [plasma membrane] (Canis familiaris)
RHOA:GTP:RTKN:TAX1BP3 [plasma membrane] (Canis familiaris)
RHOA:GTP:RTKN [plasma membrane] (Canis familiaris)
RHOA:GTP [plasma membrane] (Canis familiaris)
RHO GTPases activate CIT (Canis familiaris)
Activated CIT binds KIF14 and PRC1 (Canis familiaris)
RHOA,RHOB,RHOC,RAC1:GTP:CIT [plasma membrane] (Canis familiaris)
RHOA,RHOB,RHOC,RAC1:GTP [plasma membrane] (Canis familiaris)
RHOA:GTP [plasma membrane] (Canis familiaris)
RHOA,RHOB,RHOC,RAC1:GTP:CIT:KIF14:PRC1 [plasma membrane] (Canis familiaris)
RHOA,RHOB,RHOC,RAC1:GTP:CIT [plasma membrane] (Canis familiaris)
RHOA,RHOB,RHOC,RAC1:GTP [plasma membrane] (Canis familiaris)
RHOA:GTP [plasma membrane] (Canis familiaris)
CIT-3 binds DLG4 (Canis familiaris)
RHOA,RHOB,RHOC,RAC1:GTP:CIT-3 [plasma membrane] (Canis familiaris)
RHOA,RHOB,RHOC,RAC1:GTP [plasma membrane] (Canis familiaris)
RHOA:GTP [plasma membrane] (Canis familiaris)
RHOA,RHOB,RHOC,RAC1:GTP:CIT-3:DLG4 [plasma membrane] (Canis familiaris)
RHOA,RHOB,RHOC,RAC1:GTP:CIT-3 [plasma membrane] (Canis familiaris)
RHOA,RHOB,RHOC,RAC1:GTP [plasma membrane] (Canis familiaris)
RHOA:GTP [plasma membrane] (Canis familiaris)
RHO GTPase cycle (Canis familiaris)
RHOA GTPase cycle (Canis familiaris)
RHOA GAPs stimulate RHOA GTPase activity (Canis familiaris)
RHOA:GTP [plasma membrane] (Canis familiaris)
RHOA GEFs activate RHOA (Canis familiaris)
RHOA:GTP [plasma membrane] (Canis familiaris)
RHOA binds effectors at the plasma membrane (Canis familiaris)
RHOA:GTP [plasma membrane] (Canis familiaris)
RHOA:GTP:cytosolic RHOA effectors [plasma membrane] (Canis familiaris)
RHOA:GTP [plasma membrane] (Canis familiaris)
RHOA:GTP translocates to the ER membrane (Canis familiaris)
RHOA:GTP [plasma membrane] (Canis familiaris)
General
This complex/polymer has been computationally inferred (based on PANTHER) from a complex/polymer involved in an event that has been demonstrated in another species.
Participants
components
GTP [cytosol]
RHOA [plasma membrane]
(Canis familiaris)
Participates
as an input of
RHOA GAPs stimulate RHOA GTPase activity (Canis familiaris)
RHOA binds effectors at the plasma membrane (Canis familiaris)
RHOA:GTP translocates to the ER membrane (Canis familiaris)
RHOA:GTP binds RHPN1 or RHPN2 (Canis familiaris)
MYO9B inactivates RHOA (Canis familiaris)
DIAPH1 binds RHOA:GTP (Canis familiaris)
Inactivation of Rho-GTP by p190RhoGAP (Canis familiaris)
RHOA:GTP:Mg2+ binds ROCK1,ROCK2 (Canis familiaris)
RHOA:GTP binds ROCK, activating it (Canis familiaris)
ARHGAP35 binds RHOA:GTP (Canis familiaris)
as a component of
RHOA:GTP:cytosolic RHOA effectors [plasma membrane] (Canis familiaris)
RHOA:GTP:RHPN1,RHPN2 [plasma membrane] (Canis familiaris)
RHOA:GTP:RTKN:LIN7B [plasma membrane] (Canis familiaris)
RHOA:GTP:RTKN [plasma membrane] (Canis familiaris)
RHOA:GTP:DIAPH1 [plasma membrane] (Canis familiaris)
RHOA:GTP:ROCK1,ROCK2 [plasma membrane] (Canis familiaris)
p-Y1105-ARHGAP35:RHOA:GTP [cytosol] (Canis familiaris)
as an output of
RHOA GEFs activate RHOA (Canis familiaris)
p115-RhoGEF activation of RHOA (Canis familiaris)
NGEF exchanges GTP for GDP on RHOA (Canis familiaris)
p190RhoGEF exchanges GTP for GDP on RHOA, activating it (Canis familiaris)
RhoA is activated by nucleotide exchange and inhibits axonal growth (Canis familiaris)
as a member of
RHOA,RHOB,RHOC,RAC1:GTP [plasma membrane] (Canis familiaris)
Inferred From
RHOA:GTP [plasma membrane]
(Homo sapiens)
© 2024
Reactome
Cite Us!
Cite Us!
Cite Us!
Warning!
Unable to extract citation. Please try again later.
Download As:
BibTeX
RIS
Text