Reactome | phospho-H2AX [nucleoplasm]

phospho-H2AX [nucleoplasm]

Stable Identifier

R-CFA-5683942

Type

Protein [EntityWithAccessionedSequence]

Species

Canis familiaris

Compartment

nucleoplasm

Synonyms

p-Y143-H2AFX, E2RNB0

Locations in the PathwayBrowser

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External Reference Information

External Reference

UniProt:E2RNB0

Gene Names

H2AX

Reference Genes

BioGPS Gene:489372 H2AX

ENSEMBL:ENSCAFG00000012332

ENSEMBL_canis_lupus_familiaris_GENE:ENSCAFG00000012332 H2AX

KEGG Gene (Canis lupus familiaris):489372 H2AX

Monarch:489372 H2AX

NCBI Gene:489372 H2AX

Reference Transcript

RefSeq:XM_005619685.2 H2AX

Other Identifiers

489372

GO:0000003

GO:0000077

GO:0000228

GO:0000724

GO:0000781

GO:0000785

GO:0000786

GO:0000790

GO:0000794

GO:0001673

GO:0001741

GO:0003674

GO:0003677

GO:0003684

GO:0005575

GO:0005622

GO:0005634

GO:0005654

GO:0005657

GO:0005694

GO:0005813

GO:0005815

GO:0005856

GO:0006259

GO:0006281

GO:0006325

GO:0006342

GO:0006950

GO:0006974

GO:0007049

GO:0007283

GO:0008150

GO:0009058

GO:0016607

GO:0019899

GO:0032991

GO:0034641

GO:0035861

GO:0042393

GO:0043226

GO:0046982

GO:0051276

GO:0090734

Participant Of

hasComponent

p-Y142-H2AFX-Nucleosome [nucleoplasm]

Other forms of this molecule

H2AX [nucleoplasm]

phospho-H2AX [nucleoplasm]

Inferred From

p-Y143-H2AFX [nucleoplasm] (Homo sapiens)

Modified Residues

Name

O4'-phospho-L-tyrosine at 143 (in Homo sapiens)

Coordinate

143

PsiMod Name

O4'-phospho-L-tyrosine [MOD:00048]

PsiMod Definition

A protein modification that effectively converts an L-tyrosine residue to O4'-phospho-L-tyrosine.

Cross References

RefSeq

XP_005619742.1

Target Pathogen

57c08b76be737e1cc0a95c6b, 5b2801b2be737e35a6deb2fb, 57c09037be737e1cc0a96c46, 5b2801b3be737e35a6dec4c7, 5b2801b3be737e35a6df19d6, 57c08b76be737e1cc0a95c69

OpenTargets

ENSG00000188486

Ensembl

ENSCAFP00000032726, ENSCAFG00000012332, ENSCAFT00000019578

VGNC

83734