Toggle navigation
About
What is Reactome ?
News
Team
Scientific Advisory Board
Editorial Calendar
Statistics
Our Logo
License Agreement
Disclaimer
Content
Table of Contents
DOIs
Data Schema
ORCID Integration Project
Overlays
DisGeNET
Web
API
Docs
Userguide
Pathway Browser
How do I search ?
Details Panel
Analysis Tools
Diseases
ReactomeFIViz
Developer's Zone
Graph Database
Analysis Service
Content Service
Pathways Overview
Pathway Diagrams
Icon Info
EHLD Specs & Guidelines
Icon Library Guidelines
Data Model
Computationally inferred events
Linking to Us
Citing us
Tools
Pathway Browser
Analyze Data
ReactomeGSA
Species Comparison
Analysis Service
Content Service
ReactomeFIViz
Advanced Data Search
Site Search
Community
Icon Library
Outreach
Events
Training
Publications
Partners
Papers Citing Us
Resources Guide
Collaboration
Download
About
What is Reactome ?
News
Team
Scientific Advisory Board
Editorial Calendar
Statistics
Our Logo
License Agreement
Disclaimer
Content
Table of Contents
DOIs
Data Schema
ORCID Integration Project
Overlays
DisGeNET
Web
API
Docs
Userguide
Pathway Browser
How do I search ?
Details Panel
Analysis Tools
Diseases
ReactomeFIViz
Developer's Zone
Graph Database
Analysis Service
Content Service
Pathways Overview
Pathway Diagrams
Icon Info
EHLD Specs & Guidelines
Icon Library Guidelines
Data Model
Computationally inferred events
Linking to Us
Citing us
Tools
Pathway Browser
Analyze Data
ReactomeGSA
Species Comparison
Analysis Service
Content Service
ReactomeFIViz
Advanced Data Search
Site Search
Community
Icon Library
Outreach
Events
Training
Publications
Partners
Papers Citing Us
Resources Guide
Collaboration
Download
Search ...
Go!
BLM,WRN [nucleoplasm]
Stable Identifier
R-CFA-5685968
Type
Set [CandidateSet]
Species
Canis familiaris
Compartment
nucleoplasm
Locations in the PathwayBrowser
Expand all
DNA Repair (Canis familiaris)
DNA Double-Strand Break Repair (Canis familiaris)
Homology Directed Repair (Canis familiaris)
HDR through Homologous Recombination (HRR) or Single Strand Annealing (SSA) (Canis familiaris)
HDR through Homologous Recombination (HRR) (Canis familiaris)
D-loop extension by DNA polymerases (Canis familiaris)
D-Loop:p-MRN:p-S1981,Ac-K3016-ATM:KAT5:EXO1,DNA2:BLM,WRN:p-S990,Ac-K1249-BRIP1:p-BRCA1-C complex:PALB2:p-T3387-BRCA2:p-T309-RAD51:RAD51AP1:CX3 complex [nucleoplasm] (Canis familiaris)
D-Loop:p-MRN:p-S1981,Ac-K3016-ATM:KAT5:EXO1,DNA2:BLM,WRN:p-S990,Ac-K1249-BRIP1:p-BRCA1-C complex:PALB2:p-T3387-BRCA2:p-T309-RAD51:RAD51AP1 [nucleoplasm] (Canis familiaris)
EXO1,DNA2:BLM,WRN [nucleoplasm] (Canis familiaris)
EXO1:BLM,WRN [nucleoplasm] (Canis familiaris)
BLM,WRN [nucleoplasm] (Canis familiaris)
Extended D-Loop:p-MRN:p-S1981,Ac-K3016-ATM:KAT5:EXO1,DNA2:BLM,WRN:p-S990,Ac-K1249-BRIP1:p-BRCA1-C complex:PALB2:p-T3387-BRCA2:p-T309-RAD51:RAD51AP1:CX3 complex [nucleoplasm] (Canis familiaris)
Extended D-Loop:p-MRN:p-S1981,Ac-K3016-ATM:KAT5:EXO1,DNA2:BLM,WRN:p-S990,Ac-K1249-BRIP1:p-BRCA1-C complex:PALB2:p-T3387-BRCA2:p-T309-RAD51:RAD51AP1 [nucleoplasm] (Canis familiaris)
EXO1,DNA2:BLM,WRN [nucleoplasm] (Canis familiaris)
EXO1:BLM,WRN [nucleoplasm] (Canis familiaris)
BLM,WRN [nucleoplasm] (Canis familiaris)
Homologous DNA Pairing and Strand Exchange (Canis familiaris)
CX3 complex binds D-loop structures (Canis familiaris)
D-Loop:p-MRN:p-S1981,Ac-K3016-ATM:KAT5:EXO1,DNA2:BLM,WRN:p-S990,Ac-K1249-BRIP1:p-BRCA1-C complex:PALB2:p-T3387-BRCA2:p-T309-RAD51:RAD51AP1 [nucleoplasm] (Canis familiaris)
EXO1,DNA2:BLM,WRN [nucleoplasm] (Canis familiaris)
EXO1:BLM,WRN [nucleoplasm] (Canis familiaris)
BLM,WRN [nucleoplasm] (Canis familiaris)
D-Loop:p-MRN:p-S1981,Ac-K3016-ATM:KAT5:EXO1,DNA2:BLM,WRN:p-S990,Ac-K1249-BRIP1:p-BRCA1-C complex:PALB2:p-T3387-BRCA2:p-T309-RAD51:RAD51AP1:CX3 complex [nucleoplasm] (Canis familiaris)
D-Loop:p-MRN:p-S1981,Ac-K3016-ATM:KAT5:EXO1,DNA2:BLM,WRN:p-S990,Ac-K1249-BRIP1:p-BRCA1-C complex:PALB2:p-T3387-BRCA2:p-T309-RAD51:RAD51AP1 [nucleoplasm] (Canis familiaris)
EXO1,DNA2:BLM,WRN [nucleoplasm] (Canis familiaris)
EXO1:BLM,WRN [nucleoplasm] (Canis familiaris)
BLM,WRN [nucleoplasm] (Canis familiaris)
D-loop formation mediated by PALB2, BRCA2 and RAD51 (Canis familiaris)
3' overhanging ssDNA-DSBs:p-MRN:p-S1981,Ac-K3016-ATM:KAT5:BRCA1-C complex:EXO1,DNA2:BLM,WRN:p-S990,Ac-K1249-BRIP1:p-T309-RAD51:p-T3387-BRCA2:BCDX2 complex [nucleoplasm] (Canis familiaris)
3' overhanging ssDNA-DSBs:p-MRN:p-S1981,Ac-K3016-ATM:KAT5:BRCA1-C complex:EXO1,DNA2:BLM,WRN:p-S990,Ac-K1249-BRIP1:p-T309-RAD51:p-T3387-BRCA2 [nucleoplasm] (Canis familiaris)
EXO1,DNA2:BLM,WRN [nucleoplasm] (Canis familiaris)
EXO1:BLM,WRN [nucleoplasm] (Canis familiaris)
BLM,WRN [nucleoplasm] (Canis familiaris)
D-Loop:p-MRN:p-S1981,Ac-K3016-ATM:KAT5:EXO1,DNA2:BLM,WRN:p-S990,Ac-K1249-BRIP1:p-BRCA1-C complex:PALB2:p-T3387-BRCA2:p-T309-RAD51:RAD51AP1 [nucleoplasm] (Canis familiaris)
EXO1,DNA2:BLM,WRN [nucleoplasm] (Canis familiaris)
EXO1:BLM,WRN [nucleoplasm] (Canis familiaris)
BLM,WRN [nucleoplasm] (Canis familiaris)
Presynaptic phase of homologous DNA pairing and strand exchange (Canis familiaris)
BCDX2 complex stabilizes RAD51 filament (Canis familiaris)
3' overhanging ssDNA-DSBs:p-MRN:p-S1981,Ac-K3016-ATM:KAT5:BRCA1-C complex:EXO1,DNA2:BLM,WRN:p-S990,Ac-K1249-BRIP1:p-T309-RAD51:p-T3387-BRCA2 [nucleoplasm] (Canis familiaris)
EXO1,DNA2:BLM,WRN [nucleoplasm] (Canis familiaris)
EXO1:BLM,WRN [nucleoplasm] (Canis familiaris)
BLM,WRN [nucleoplasm] (Canis familiaris)
3' overhanging ssDNA-DSBs:p-MRN:p-S1981,Ac-K3016-ATM:KAT5:BRCA1-C complex:EXO1,DNA2:BLM,WRN:p-S990,Ac-K1249-BRIP1:p-T309-RAD51:p-T3387-BRCA2:BCDX2 complex [nucleoplasm] (Canis familiaris)
3' overhanging ssDNA-DSBs:p-MRN:p-S1981,Ac-K3016-ATM:KAT5:BRCA1-C complex:EXO1,DNA2:BLM,WRN:p-S990,Ac-K1249-BRIP1:p-T309-RAD51:p-T3387-BRCA2 [nucleoplasm] (Canis familiaris)
EXO1,DNA2:BLM,WRN [nucleoplasm] (Canis familiaris)
EXO1:BLM,WRN [nucleoplasm] (Canis familiaris)
BLM,WRN [nucleoplasm] (Canis familiaris)
RAD51 binds BRCA2 at resected DNA DSBs (Canis familiaris)
3' overhanging ssDNA-DSBs:p-MRN:p-S1981,Ac-K3016-ATM:KAT5:BRCA1-C complex:EXO1,DNA2:BLM,WRN:p-S990,Ac-K1249-BRIP1:p-T309-RAD51:p-T3387-BRCA2 [nucleoplasm] (Canis familiaris)
EXO1,DNA2:BLM,WRN [nucleoplasm] (Canis familiaris)
EXO1:BLM,WRN [nucleoplasm] (Canis familiaris)
BLM,WRN [nucleoplasm] (Canis familiaris)
ATR:ATRIP:p-RPA:3' overhanging ssDNA-DSBs:p-MRN:p-S1981,Ac-K3016-ATM:KAT5:BRCA1-C complex:EXO1,DNA2:BLM,WRN:p-S990,Ac-K1249-BRIP1:RAD17:RFC:RAD9:HUS1:RAD1:RHNO1:TOPBP1 [nucleoplasm] (Canis familiaris)
EXO1,DNA2:BLM,WRN [nucleoplasm] (Canis familiaris)
EXO1:BLM,WRN [nucleoplasm] (Canis familiaris)
BLM,WRN [nucleoplasm] (Canis familiaris)
Resolution of D-Loop Structures (Canis familiaris)
Resolution of D-loop Structures through Holliday Junction Intermediates (Canis familiaris)
Cleavage of Holliday junctions by GEN1 or SLX1A:SLX4:MUS81:EME1,(MUS81:EME2) (Canis familiaris)
Cleaved Holliday Junction:p-MRN:p-S1981,Ac-K3016-ATM:KAT5:EXO1,DNA2:BLM,WRN:p-BRCA1-C complex:PALB2:p-T3387-BRCA2:p-T309-RAD51:RAD51AP1:CX3 complex [nucleoplasm] (Canis familiaris)
Cleaved Holliday Junction:p-MRN:p-S1981,Ac-K3016-ATM:KAT5:EXO1,DNA2:BLM,WRN:p-BRCA1-C complex:PALB2:p-T3387-BRCA2:p-T309-RAD51:RAD51AP1 [nucleoplasm] (Canis familiaris)
EXO1,DNA2:BLM,WRN [nucleoplasm] (Canis familiaris)
EXO1:BLM,WRN [nucleoplasm] (Canis familiaris)
BLM,WRN [nucleoplasm] (Canis familiaris)
Holliday Junction:p-MRN:p-S1981,Ac-K3016-ATM:KAT5:EXO1,DNA2:BLM,WRN:p-S990,Ac-K1249-BRIP1:p-BRCA1-C complex:PALB2:p-T3387-BRCA2:p-T309-RAD51:RAD51AP1:CX3 complex [nucleoplasm] (Canis familiaris)
Holliday Junction:p-MRN:p-S1981,Ac-K3016-ATM:KAT5:EXO1,DNA2:BLM,WRN:p-S990,Ac-K1249-BRIP1:p-BRCA1-C complex:PALB2:p-T3387-BRCA2:p-T309-RAD51:RAD51AP1 [nucleoplasm] (Canis familiaris)
EXO1,DNA2:BLM,WRN [nucleoplasm] (Canis familiaris)
EXO1:BLM,WRN [nucleoplasm] (Canis familiaris)
BLM,WRN [nucleoplasm] (Canis familiaris)
Ligation of DNA and formation of Holliday structures following repair synthesis (Canis familiaris)
Extended D-Loop:p-MRN:p-S1981,Ac-K3016-ATM:KAT5:EXO1,DNA2:BLM,WRN:p-S990,Ac-K1249-BRIP1:p-BRCA1-C complex:PALB2:p-T3387-BRCA2:p-T309-RAD51:RAD51AP1:CX3 complex [nucleoplasm] (Canis familiaris)
Extended D-Loop:p-MRN:p-S1981,Ac-K3016-ATM:KAT5:EXO1,DNA2:BLM,WRN:p-S990,Ac-K1249-BRIP1:p-BRCA1-C complex:PALB2:p-T3387-BRCA2:p-T309-RAD51:RAD51AP1 [nucleoplasm] (Canis familiaris)
EXO1,DNA2:BLM,WRN [nucleoplasm] (Canis familiaris)
EXO1:BLM,WRN [nucleoplasm] (Canis familiaris)
BLM,WRN [nucleoplasm] (Canis familiaris)
Holliday Junction:p-MRN:p-S1981,Ac-K3016-ATM:KAT5:EXO1,DNA2:BLM,WRN:p-S990,Ac-K1249-BRIP1:p-BRCA1-C complex:PALB2:p-T3387-BRCA2:p-T309-RAD51:RAD51AP1:CX3 complex [nucleoplasm] (Canis familiaris)
Holliday Junction:p-MRN:p-S1981,Ac-K3016-ATM:KAT5:EXO1,DNA2:BLM,WRN:p-S990,Ac-K1249-BRIP1:p-BRCA1-C complex:PALB2:p-T3387-BRCA2:p-T309-RAD51:RAD51AP1 [nucleoplasm] (Canis familiaris)
EXO1,DNA2:BLM,WRN [nucleoplasm] (Canis familiaris)
EXO1:BLM,WRN [nucleoplasm] (Canis familiaris)
BLM,WRN [nucleoplasm] (Canis familiaris)
MUS81:EME1,EME2 cleaves D-loop (Canis familiaris)
Cleaved D-Loop:p-MRN:p-S1981,Ac-K3016-ATM:KAT5:EXO1,DNA2:BLM,WRN:p-BRCA1-C complex:PALB2:p-T3387-BRCA2:p-T309-RAD51:RAD51AP1:CX3 complex [nucleoplasm] (Canis familiaris)
Cleaved D-Loop:p-MRN:p-S1981,Ac-K3016-ATM:KAT5:EXO1,DNA2:BLM,WRN:p-BRCA1-C complex:PALB2:p-T3387-BRCA2:p-T309-RAD51:RAD51AP1 [nucleoplasm] (Canis familiaris)
EXO1,DNA2:BLM,WRN [nucleoplasm] (Canis familiaris)
EXO1:BLM,WRN [nucleoplasm] (Canis familiaris)
BLM,WRN [nucleoplasm] (Canis familiaris)
Extended D-Loop:p-MRN:p-S1981,Ac-K3016-ATM:KAT5:EXO1,DNA2:BLM,WRN:p-S990,Ac-K1249-BRIP1:p-BRCA1-C complex:PALB2:p-T3387-BRCA2:p-T309-RAD51:RAD51AP1:CX3 complex [nucleoplasm] (Canis familiaris)
Extended D-Loop:p-MRN:p-S1981,Ac-K3016-ATM:KAT5:EXO1,DNA2:BLM,WRN:p-S990,Ac-K1249-BRIP1:p-BRCA1-C complex:PALB2:p-T3387-BRCA2:p-T309-RAD51:RAD51AP1 [nucleoplasm] (Canis familiaris)
EXO1,DNA2:BLM,WRN [nucleoplasm] (Canis familiaris)
EXO1:BLM,WRN [nucleoplasm] (Canis familiaris)
BLM,WRN [nucleoplasm] (Canis familiaris)
HDR through Single Strand Annealing (SSA) (Canis familiaris)
Association of RAD51 with RAD52:DNA double-strand break ends (Canis familiaris)
RAD51:p-Y104-RAD52:p-RPA:ATR:ATRIP:3' overhanging ssDNA-DSBs:p-MRN:p-S1981,Ac-K3016-ATM:KAT5:BRCA1-C complex:EXO1,DNA2:BLM,WRN:p-S990,Ac-K1249-BRIP1:RAD17:RFC:RAD9:HUS1:RAD1:RHNO1:TOPBP1 [nucleoplasm] (Canis familiaris)
p-Y104-RAD52:p-RPA:ATR:ATRIP:3' overhanging ssDNA-DSBs:p-MRN:p-S1981,Ac-K3016-ATM:KAT5:BRCA1-C complex:EXO1,DNA2:BLM,WRN:p-S990,Ac-K1249-BRIP1:RAD17:RFC:RAD9:HUS1:RAD1:RHNO1:TOPBP1 [nucleoplasm] (Canis familiaris)
ATR:ATRIP:p-RPA:3' overhanging ssDNA-DSBs:p-MRN:p-S1981,Ac-K3016-ATM:KAT5:BRCA1-C complex:EXO1,DNA2:BLM,WRN:p-S990,Ac-K1249-BRIP1:RAD17:RFC:RAD9:HUS1:RAD1:RHNO1:TOPBP1 [nucleoplasm] (Canis familiaris)
EXO1,DNA2:BLM,WRN [nucleoplasm] (Canis familiaris)
EXO1:BLM,WRN [nucleoplasm] (Canis familiaris)
BLM,WRN [nucleoplasm] (Canis familiaris)
p-Y104-RAD52:p-RPA:ATR:ATRIP:3' overhanging ssDNA-DSBs:p-MRN:p-S1981,Ac-K3016-ATM:KAT5:BRCA1-C complex:EXO1,DNA2:BLM,WRN:p-S990,Ac-K1249-BRIP1:RAD17:RFC:RAD9:HUS1:RAD1:RHNO1:TOPBP1 [nucleoplasm] (Canis familiaris)
ATR:ATRIP:p-RPA:3' overhanging ssDNA-DSBs:p-MRN:p-S1981,Ac-K3016-ATM:KAT5:BRCA1-C complex:EXO1,DNA2:BLM,WRN:p-S990,Ac-K1249-BRIP1:RAD17:RFC:RAD9:HUS1:RAD1:RHNO1:TOPBP1 [nucleoplasm] (Canis familiaris)
EXO1,DNA2:BLM,WRN [nucleoplasm] (Canis familiaris)
EXO1:BLM,WRN [nucleoplasm] (Canis familiaris)
BLM,WRN [nucleoplasm] (Canis familiaris)
Association of RAD52 with the RPA complex at resected DNA DSBs (Canis familiaris)
ATR:ATRIP:p-RPA:3' overhanging ssDNA-DSBs:p-MRN:p-S1981,Ac-K3016-ATM:KAT5:BRCA1-C complex:EXO1,DNA2:BLM,WRN:p-S990,Ac-K1249-BRIP1:RAD17:RFC:RAD9:HUS1:RAD1:RHNO1:TOPBP1 [nucleoplasm] (Canis familiaris)
EXO1,DNA2:BLM,WRN [nucleoplasm] (Canis familiaris)
EXO1:BLM,WRN [nucleoplasm] (Canis familiaris)
BLM,WRN [nucleoplasm] (Canis familiaris)
p-Y104-RAD52:p-RPA:ATR:ATRIP:3' overhanging ssDNA-DSBs:p-MRN:p-S1981,Ac-K3016-ATM:KAT5:BRCA1-C complex:EXO1,DNA2:BLM,WRN:p-S990,Ac-K1249-BRIP1:RAD17:RFC:RAD9:HUS1:RAD1:RHNO1:TOPBP1 [nucleoplasm] (Canis familiaris)
ATR:ATRIP:p-RPA:3' overhanging ssDNA-DSBs:p-MRN:p-S1981,Ac-K3016-ATM:KAT5:BRCA1-C complex:EXO1,DNA2:BLM,WRN:p-S990,Ac-K1249-BRIP1:RAD17:RFC:RAD9:HUS1:RAD1:RHNO1:TOPBP1 [nucleoplasm] (Canis familiaris)
EXO1,DNA2:BLM,WRN [nucleoplasm] (Canis familiaris)
EXO1:BLM,WRN [nucleoplasm] (Canis familiaris)
BLM,WRN [nucleoplasm] (Canis familiaris)
RAD52 promotes single strand annealing at resected DNA DSBs (Canis familiaris)
RAD51:p-Y104-RAD52:p-RPA:ATR:ATRIP:3' overhanging ssDNA-DSBs:p-MRN:p-S1981,Ac-K3016-ATM:KAT5:BRCA1-C complex:EXO1,DNA2:BLM,WRN:p-S990,Ac-K1249-BRIP1:RAD17:RFC:RAD9:HUS1:RAD1:RHNO1:TOPBP1 [nucleoplasm] (Canis familiaris)
p-Y104-RAD52:p-RPA:ATR:ATRIP:3' overhanging ssDNA-DSBs:p-MRN:p-S1981,Ac-K3016-ATM:KAT5:BRCA1-C complex:EXO1,DNA2:BLM,WRN:p-S990,Ac-K1249-BRIP1:RAD17:RFC:RAD9:HUS1:RAD1:RHNO1:TOPBP1 [nucleoplasm] (Canis familiaris)
ATR:ATRIP:p-RPA:3' overhanging ssDNA-DSBs:p-MRN:p-S1981,Ac-K3016-ATM:KAT5:BRCA1-C complex:EXO1,DNA2:BLM,WRN:p-S990,Ac-K1249-BRIP1:RAD17:RFC:RAD9:HUS1:RAD1:RHNO1:TOPBP1 [nucleoplasm] (Canis familiaris)
EXO1,DNA2:BLM,WRN [nucleoplasm] (Canis familiaris)
EXO1:BLM,WRN [nucleoplasm] (Canis familiaris)
BLM,WRN [nucleoplasm] (Canis familiaris)
RAD51:p-Y104-RAD52:p-RPA:ATR:ATRIP:DNA DSBs with annealed 3' ssDNA overhangs and displaced flaps:p-MRN:p-S1981,Ac-K3016-ATM:KAT5:BRCA1-C complex:EXO1,DNA2:BLM,WRN:p-S990,Ac-K1249-BRIP1:RAD17:RFC:RAD9:HUS1:RAD1:RHNO1:TOPBP1 [nucleoplasm] (Canis familiaris)
p-Y104-RAD52:p-RPA:ATR:ATRIP:DNA DSBs with annealed 3' ssDNA overhangs and displaced flaps:p-MRN:p-S1981,Ac-K3016-ATM:KAT5:BRCA1-C complex:EXO1,DNA2:BLM,WRN:p-S990,Ac-K1249-BRIP1:RAD17:RFC:RAD9:HUS1:RAD1:RHNO1:TOPBP1 [nucleoplasm] (Canis familiaris)
ATR:ATRIP:p-RPA:DNA DSBs with annealed 3' ssDNA overhangs and displaced flaps:p-MRN:p-S1981,Ac-K3016-ATM:KAT5:BRCA1-C complex:EXO1,DNA2:BLM,WRN:p-S990,Ac-K1249-BRIP1:RAD17:RFC:RAD9:HUS1:RAD1:RHNO1:TOPBP1 [nucleoplasm] (Canis familiaris)
EXO1,DNA2:BLM,WRN [nucleoplasm] (Canis familiaris)
EXO1:BLM,WRN [nucleoplasm] (Canis familiaris)
BLM,WRN [nucleoplasm] (Canis familiaris)
Processing of DNA double-strand break ends (Canis familiaris)
ATR activation at DNA DSBs (Canis familiaris)
ATR:ATRIP:RPA:3' overhanging ssDNA-DSBs:p-MRN:p-S1981,Ac-K3016-ATM:KAT5:BRCA1-C complex:EXO1,DNA2:BLM,WRN:p-S990,Ac-K1249-BRIP1 [nucleoplasm] (Canis familiaris)
RPA:3' overhanging ssDNA-DSBs:p-MRN:p-S1981,Ac-K3016-ATM:KAT5:BRCA1-C complex:EXO1,DNA2:BLM,WRN:p-S990,Ac-K1249-BRIP1 [nucleoplasm] (Canis familiaris)
3' overhanging ssDNA-DSBs:p-MRN:p-S1981,Ac-K3016-ATM:KAT5:BRCA1-C complex:EXO1,DNA2:BLM,WRN:p-S990,Ac-K1249-BRIP1 [nucleoplasm] (Canis familiaris)
EXO1,DNA2:BLM,WRN [nucleoplasm] (Canis familiaris)
EXO1:BLM,WRN [nucleoplasm] (Canis familiaris)
BLM,WRN [nucleoplasm] (Canis familiaris)
ATR:ATRIP:RPA:3' overhanging ssDNA-DSBs:p-MRN:p-S1981,Ac-K3016-ATM:KAT5:BRCA1-C complex:EXO1,DNA2:BLM,WRN:p-S990,Ac-K1249-BRIP1:RAD17:RFC:RAD9:HUS1:RAD1:RHNO1:TOPBP1 [nucleoplasm] (Canis familiaris)
ATR:ATRIP:RPA:3' overhanging ssDNA-DSBs:p-MRN:p-S1981,Ac-K3016-ATM:KAT5:BRCA1-C complex:EXO1,DNA2:BLM,WRN:p-S990,Ac-K1249-BRIP1 [nucleoplasm] (Canis familiaris)
RPA:3' overhanging ssDNA-DSBs:p-MRN:p-S1981,Ac-K3016-ATM:KAT5:BRCA1-C complex:EXO1,DNA2:BLM,WRN:p-S990,Ac-K1249-BRIP1 [nucleoplasm] (Canis familiaris)
3' overhanging ssDNA-DSBs:p-MRN:p-S1981,Ac-K3016-ATM:KAT5:BRCA1-C complex:EXO1,DNA2:BLM,WRN:p-S990,Ac-K1249-BRIP1 [nucleoplasm] (Canis familiaris)
EXO1,DNA2:BLM,WRN [nucleoplasm] (Canis familiaris)
EXO1:BLM,WRN [nucleoplasm] (Canis familiaris)
BLM,WRN [nucleoplasm] (Canis familiaris)
ATR phosphorylates RPA2 (Canis familiaris)
ATR:ATRIP:RPA:3' overhanging ssDNA-DSBs:p-MRN:p-S1981,Ac-K3016-ATM:KAT5:BRCA1-C complex:EXO1,DNA2:BLM,WRN:p-S990,Ac-K1249-BRIP1:RAD17:RFC:RAD9:HUS1:RAD1:RHNO1:TOPBP1 [nucleoplasm] (Canis familiaris)
ATR:ATRIP:RPA:3' overhanging ssDNA-DSBs:p-MRN:p-S1981,Ac-K3016-ATM:KAT5:BRCA1-C complex:EXO1,DNA2:BLM,WRN:p-S990,Ac-K1249-BRIP1 [nucleoplasm] (Canis familiaris)
RPA:3' overhanging ssDNA-DSBs:p-MRN:p-S1981,Ac-K3016-ATM:KAT5:BRCA1-C complex:EXO1,DNA2:BLM,WRN:p-S990,Ac-K1249-BRIP1 [nucleoplasm] (Canis familiaris)
3' overhanging ssDNA-DSBs:p-MRN:p-S1981,Ac-K3016-ATM:KAT5:BRCA1-C complex:EXO1,DNA2:BLM,WRN:p-S990,Ac-K1249-BRIP1 [nucleoplasm] (Canis familiaris)
EXO1,DNA2:BLM,WRN [nucleoplasm] (Canis familiaris)
EXO1:BLM,WRN [nucleoplasm] (Canis familiaris)
BLM,WRN [nucleoplasm] (Canis familiaris)
ATR:ATRIP:p-RPA:3' overhanging ssDNA-DSBs:p-MRN:p-S1981,Ac-K3016-ATM:KAT5:BRCA1-C complex:EXO1,DNA2:BLM,WRN:p-S990,Ac-K1249-BRIP1:RAD17:RFC:RAD9:HUS1:RAD1:RHNO1:TOPBP1 [nucleoplasm] (Canis familiaris)
EXO1,DNA2:BLM,WRN [nucleoplasm] (Canis familiaris)
EXO1:BLM,WRN [nucleoplasm] (Canis familiaris)
BLM,WRN [nucleoplasm] (Canis familiaris)
Activation of CHEK1 at resected DNA DSBs (Canis familiaris)
ATR:ATRIP:p-RPA:3' overhanging ssDNA-DSBs:p-MRN:p-S1981,Ac-K3016-ATM:KAT5:BRCA1-C complex:EXO1,DNA2:BLM,WRN:p-S990,Ac-K1249-BRIP1:RAD17:RFC:RAD9:HUS1:RAD1:RHNO1:TOPBP1 [nucleoplasm] (Canis familiaris)
EXO1,DNA2:BLM,WRN [nucleoplasm] (Canis familiaris)
EXO1:BLM,WRN [nucleoplasm] (Canis familiaris)
BLM,WRN [nucleoplasm] (Canis familiaris)
ATR:ATRIP:p-RPA:3' overhanging ssDNA-DSBs:p-MRN:p-S1981,Ac-K3016-ATM:KAT5:BRCA1-C complex:EXO1,DNA2:BLM,WRN:p-S990,Ac-K1249-BRIP1:RAD17:RFC:RAD9:HUS1:RAD1:RHNO1:TOPBP1:TIMELESS:TIPIN:p-T916,S945-CLSPN:CHEK1 [nucleoplasm] (Canis familiaris)
EXO1,DNA2:BLM,WRN [nucleoplasm] (Canis familiaris)
EXO1:BLM,WRN [nucleoplasm] (Canis familiaris)
BLM,WRN [nucleoplasm] (Canis familiaris)
Association of RPA complexes with ssDNA at resected DNA DSBs (Canis familiaris)
3' overhanging ssDNA-DSBs:p-MRN:p-S1981,Ac-K3016-ATM:KAT5:BRCA1-C complex:EXO1,DNA2:BLM,WRN:p-S990,Ac-K1249-BRIP1 [nucleoplasm] (Canis familiaris)
EXO1,DNA2:BLM,WRN [nucleoplasm] (Canis familiaris)
EXO1:BLM,WRN [nucleoplasm] (Canis familiaris)
BLM,WRN [nucleoplasm] (Canis familiaris)
RPA:3' overhanging ssDNA-DSBs:p-MRN:p-S1981,Ac-K3016-ATM:KAT5:BRCA1-C complex:EXO1,DNA2:BLM,WRN:p-S990,Ac-K1249-BRIP1 [nucleoplasm] (Canis familiaris)
3' overhanging ssDNA-DSBs:p-MRN:p-S1981,Ac-K3016-ATM:KAT5:BRCA1-C complex:EXO1,DNA2:BLM,WRN:p-S990,Ac-K1249-BRIP1 [nucleoplasm] (Canis familiaris)
EXO1,DNA2:BLM,WRN [nucleoplasm] (Canis familiaris)
EXO1:BLM,WRN [nucleoplasm] (Canis familiaris)
BLM,WRN [nucleoplasm] (Canis familiaris)
Binding of ATR:ATRIP to RPA at resected DNA DSBs (Canis familiaris)
ATR:ATRIP:RPA:3' overhanging ssDNA-DSBs:p-MRN:p-S1981,Ac-K3016-ATM:KAT5:BRCA1-C complex:EXO1,DNA2:BLM,WRN:p-S990,Ac-K1249-BRIP1 [nucleoplasm] (Canis familiaris)
RPA:3' overhanging ssDNA-DSBs:p-MRN:p-S1981,Ac-K3016-ATM:KAT5:BRCA1-C complex:EXO1,DNA2:BLM,WRN:p-S990,Ac-K1249-BRIP1 [nucleoplasm] (Canis familiaris)
3' overhanging ssDNA-DSBs:p-MRN:p-S1981,Ac-K3016-ATM:KAT5:BRCA1-C complex:EXO1,DNA2:BLM,WRN:p-S990,Ac-K1249-BRIP1 [nucleoplasm] (Canis familiaris)
EXO1,DNA2:BLM,WRN [nucleoplasm] (Canis familiaris)
EXO1:BLM,WRN [nucleoplasm] (Canis familiaris)
BLM,WRN [nucleoplasm] (Canis familiaris)
RPA:3' overhanging ssDNA-DSBs:p-MRN:p-S1981,Ac-K3016-ATM:KAT5:BRCA1-C complex:EXO1,DNA2:BLM,WRN:p-S990,Ac-K1249-BRIP1 [nucleoplasm] (Canis familiaris)
3' overhanging ssDNA-DSBs:p-MRN:p-S1981,Ac-K3016-ATM:KAT5:BRCA1-C complex:EXO1,DNA2:BLM,WRN:p-S990,Ac-K1249-BRIP1 [nucleoplasm] (Canis familiaris)
EXO1,DNA2:BLM,WRN [nucleoplasm] (Canis familiaris)
EXO1:BLM,WRN [nucleoplasm] (Canis familiaris)
BLM,WRN [nucleoplasm] (Canis familiaris)
CHEK1 is recruited to resected DNA DSBs (Canis familiaris)
ATR:ATRIP:p-RPA:3' overhanging ssDNA-DSBs:p-MRN:p-S1981,Ac-K3016-ATM:KAT5:BRCA1-C complex:EXO1,DNA2:BLM,WRN:p-S990,Ac-K1249-BRIP1:RAD17:RFC:RAD9:HUS1:RAD1:RHNO1:TOPBP1 [nucleoplasm] (Canis familiaris)
EXO1,DNA2:BLM,WRN [nucleoplasm] (Canis familiaris)
EXO1:BLM,WRN [nucleoplasm] (Canis familiaris)
BLM,WRN [nucleoplasm] (Canis familiaris)
ATR:ATRIP:p-RPA:3' overhanging ssDNA-DSBs:p-MRN:p-S1981,Ac-K3016-ATM:KAT5:BRCA1-C complex:EXO1,DNA2:BLM,WRN:p-S990,Ac-K1249-BRIP1:RAD17:RFC:RAD9:HUS1:RAD1:RHNO1:TOPBP1:TIMELESS:TIPIN:p-T916,S945-CLSPN:CHEK1 [nucleoplasm] (Canis familiaris)
EXO1,DNA2:BLM,WRN [nucleoplasm] (Canis familiaris)
EXO1:BLM,WRN [nucleoplasm] (Canis familiaris)
BLM,WRN [nucleoplasm] (Canis familiaris)
EXO1 or DNA2 in complex with BLM or WRN binds initially resected DNA DSBs along with BRIP1 recruitment (Canis familiaris)
3' short overhanging ssDNA-DSBs:p-MRN:p-S1981,Ac-K3016-ATM:KAT5:BRCA1-C complex:EXO1,DNA2:BLM,WRN:p-S990,Ac-K1249-BRIP1 [nucleoplasm] (Canis familiaris)
EXO1,DNA2:BLM,WRN [nucleoplasm] (Canis familiaris)
EXO1:BLM,WRN [nucleoplasm] (Canis familiaris)
BLM,WRN [nucleoplasm] (Canis familiaris)
EXO1,DNA2:BLM,WRN [nucleoplasm] (Canis familiaris)
EXO1:BLM,WRN [nucleoplasm] (Canis familiaris)
BLM,WRN [nucleoplasm] (Canis familiaris)
Long-range resection of DNA DSBs by EXO1 or DNA2 (Canis familiaris)
3' overhanging ssDNA-DSBs:p-MRN:p-S1981,Ac-K3016-ATM:KAT5:BRCA1-C complex:EXO1,DNA2:BLM,WRN:p-S990,Ac-K1249-BRIP1 [nucleoplasm] (Canis familiaris)
EXO1,DNA2:BLM,WRN [nucleoplasm] (Canis familiaris)
EXO1:BLM,WRN [nucleoplasm] (Canis familiaris)
BLM,WRN [nucleoplasm] (Canis familiaris)
3' short overhanging ssDNA-DSBs:p-MRN:p-S1981,Ac-K3016-ATM:KAT5:BRCA1-C complex:EXO1,DNA2:BLM,WRN:p-S990,Ac-K1249-BRIP1 [nucleoplasm] (Canis familiaris)
EXO1,DNA2:BLM,WRN [nucleoplasm] (Canis familiaris)
EXO1:BLM,WRN [nucleoplasm] (Canis familiaris)
BLM,WRN [nucleoplasm] (Canis familiaris)
Participants
candidates
BLM [nucleoplasm] (Canis familiaris)
WRN [nucleoplasm] (Canis familiaris)
Participant Of
hasComponent
EXO1:BLM,WRN [nucleoplasm]
Inferred From
BLM,WRN [nucleoplasm] (Homo sapiens)
© 2020
Reactome
Cite Us!
Cite Us!
Cite Us!
Warning!
Unable to extract citation. Please try again later.
Download As:
BibTeX
RIS
Text
