Reactome | MCFD2 [endoplasmic reticulum-Golgi intermediate compartment membrane]

MCFD2 [endoplasmic reticulum-Golgi intermediate compartment membrane]

Stable Identifier

R-CFA-5689836

Type

Protein [EntityWithAccessionedSequence]

Species

Canis familiaris

Compartment

endoplasmic reticulum-Golgi intermediate compartment membrane

Synonyms

MCFD2, A0A8I3Q3Y7

Locations in the PathwayBrowser

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Metabolism of proteins (Canis familiaris)

- Post-translational protein modification (Canis familiaris)
  - Asparagine N-linked glycosylation (Canis familiaris)
    - Transport to the Golgi and subsequent modification (Canis familiaris)
      - ER to Golgi Anterograde Transport (Canis familiaris)
        
        COPII-mediated vesicle transport (Canis familiaris)
        
        BET1:GOSR2:STX5 bind v-SNARES on tethered vesicle (Canis familiaris)
        
        COPII cargo:receptors [endoplasmic reticulum-Golgi intermediate compartment membrane] (Canis familiaris)
        
        LMAN1:MCFD2:glycosylated FV, FVIII precursor [endoplasmic reticulum-Golgi intermediate compartment membrane] (Canis familiaris)
        
        hexameric LMAN1:MCFD2 [endoplasmic reticulum-Golgi intermediate compartment membrane] (Canis familiaris)
        
        MCFD2 [endoplasmic reticulum-Golgi intermediate compartment membrane] (Canis familiaris)

Vesicle-mediated transport (Canis familiaris)

- Membrane Trafficking (Canis familiaris)
  - ER to Golgi Anterograde Transport (Canis familiaris)
    - COPII-mediated vesicle transport (Canis familiaris)
      - BET1:GOSR2:STX5 bind v-SNARES on tethered vesicle (Canis familiaris)
        
        COPII cargo:receptors [endoplasmic reticulum-Golgi intermediate compartment membrane] (Canis familiaris)
        
        LMAN1:MCFD2:glycosylated FV, FVIII precursor [endoplasmic reticulum-Golgi intermediate compartment membrane] (Canis familiaris)
        
        hexameric LMAN1:MCFD2 [endoplasmic reticulum-Golgi intermediate compartment membrane] (Canis familiaris)
        
        MCFD2 [endoplasmic reticulum-Golgi intermediate compartment membrane] (Canis familiaris)

External Reference Information

External Reference

UniProt:A0A8I3Q3Y7

Gene Names

MCFD2

Reference Genes

ENSEMBL:ENSCAFG00845028228.1

ENSEMBL_canis_lupus_familiaris_GENE:ENSCAFG00845028228.1 MCFD2

Other Identifiers

474582

Cfa.1788.1.A1_at

Cfa.21052.2.S1_s_at

GO:0005509

GO:0046872

Participates

as a component of

hexameric LMAN1:MCFD2 [endoplasmic reticulum-Golgi intermediate compartment membrane] (Canis familiaris)

Other forms of this molecule

MCFD2 [endoplasmic reticulum membrane]

MCFD2 [ER to Golgi transport vesicle membrane]

Inferred From

MCFD2 [endoplasmic reticulum-Golgi intermediate compartment membrane] (Homo sapiens)

Cross References

OpenTargets

ENSG00000180398

Ensembl

ENSCAFT00845049852, ENSCAFG00845028228, ENSCAFP00845039098

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