Reactome | RPS27A [nucleoplasm]

RPS27A [nucleoplasm]

Stable Identifier

R-CFA-6782503

Type

Protein [EntityWithAccessionedSequence]

Species

Canis familiaris

Compartment

nucleoplasm

Synonyms

Ub-63-RPS27A(1-76), F1PEZ4

Locations in the PathwayBrowser

Expand all

DNA Repair (Canis familiaris)

- Nucleotide Excision Repair (Canis familiaris)
  - Global Genome Nucleotide Excision Repair (GG-NER) (Canis familiaris)
    - Formation of Incision Complex in GG-NER (Canis familiaris)
      - RNF111 ubiquitinates SUMOylated XPC (Canis familiaris)
        
        K63polyUb:C87-UBE2N:UBE2V2 [nucleoplasm] (Canis familiaris)
        
        K63polyUb:C87-UBE2N [nucleoplasm] (Canis familiaris)
        
        K63-Ub [nucleoplasm] (Canis familiaris)
        
        RPS27A [nucleoplasm] (Canis familiaris)
        
        Ub,SUMO,K63polyUb:XPC:RAD23:CETN2 [nucleoplasm] (Canis familiaris)
        
        Ub,SUMO,K63polyUb:XPC [nucleoplasm] (Canis familiaris)
        
        K63-Ub [nucleoplasm] (Canis familiaris)
        
        RPS27A [nucleoplasm] (Canis familiaris)

Gene expression (Transcription) (Canis familiaris)

- RNA Polymerase II Transcription (Canis familiaris)
  - Generic Transcription Pathway (Canis familiaris)
    - Transcriptional Regulation by TP53 (Canis familiaris)
      - Regulation of TP53 Activity (Canis familiaris)
        
        Regulation of TP53 Expression and Degradation (Canis familiaris)
        
        Regulation of TP53 Degradation (Canis familiaris)
        
        USP2 deubiquitinates MDM2,MDM4 (Canis familiaris)
        
        PolyUb [nucleoplasm] (Canis familiaris)
        
        K63polyUb [nucleoplasm] (Canis familiaris)
        
        K63-Ub [nucleoplasm] (Canis familiaris)
        
        RPS27A [nucleoplasm] (Canis familiaris)

External Reference Information

External Reference

UniProt:F1PEZ4

Gene Names

RPS27A

Reference Genes

BioGPS Gene:474599 RPS27A

ENSEMBL:ENSCAFG00000023471

ENSEMBL_canis_lupus_familiaris_GENE:ENSCAFG00000023471 RPS27A

KEGG Gene (Canis lupus familiaris):474599 RPS27A

Monarch:474599 RPS27A

NCBI Gene:474599 RPS27A

Reference Transcript

RefSeq:NM_001252228.1 RPS27A

Other Identifiers

474599

Cfa.311.2.A1_x_at

Cfa.311.6.A1_x_at

GO:0003674

GO:0003735

GO:0005198

GO:0005575

GO:0005622

GO:0005634

GO:0005737

GO:0005829

GO:0005840

GO:0006412

GO:0006464

GO:0008150

GO:0009056

GO:0009058

GO:0015935

GO:0016567

GO:0019899

GO:0019941

GO:0022627

GO:0031386

GO:0031625

GO:0032991

GO:0034641

GO:0043167

GO:0043226

GO:0046872

Participant Of

hasMember

K63-Ub [nucleoplasm]

Other forms of this molecule

RPS27A [endocytic vesicle membrane]

RPS27A [nucleoplasm]

RPS27A [mitochondrial outer membrane]

RPS27A [cytosol]

RPS27A [nucleoplasm]

RPS27A [cytosol]

RPS27A [endosome membrane]

phospho-RPS27A [cytosol]

phospho-RPS27A [nucleoplasm]

RPS27A [cytosol]

RPS27A [mitochondrial outer membrane]

Inferred From

Ub-63-RPS27A(1-76) [nucleoplasm] (Homo sapiens)

Modified Residues

Name

ubiquitinylated lysine at 63 (in Homo sapiens)

Coordinate

PsiMod Name

ubiquitinylated lysine [MOD:01148]

PsiMod Definition

A protein modification that effectively crosslinks the N6-amino of a peptidyl lysine with the carboxyl-terminal glycine of a ubiquitin.

Cross References

RefSeq

NP_001239157.1

Target Pathogen

5b354852be737e166372eb21, 5b2801b3be737e35a6df151a

OpenTargets

ENSG00000143947

Ensembl

ENSCAFG00000023471, ENSCAFP00000031429, ENSCAFT00000036091

VGNC

54540