Reactome | H2AC15 [nucleoplasm]

H2AC15 [nucleoplasm]

Stable Identifier

R-CFA-6782508

Type

Protein [EntityWithAccessionedSequence]

Species

Canis familiaris

Compartment

nucleoplasm

Synonyms

Ub-HIST1H2AG, A0A5F4CIE3

Locations in the PathwayBrowser

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Metabolism of proteins (Canis familiaris)

- Post-translational protein modification (Canis familiaris)
  - Deubiquitination (Canis familiaris)
    - Metalloprotease DUBs (Canis familiaris)
      - MYSM1 deubiquitinates Histone H2A (Canis familiaris)
        
        MYSM1:EP300:KAT2B:Ub-histone H2A [nucleoplasm] (Canis familiaris)
        
        Ub-histone H2A [nucleoplasm] (Canis familiaris)
        
        Ub-histone HIST1 H2A [nucleoplasm] (Canis familiaris)
        
        Homologues of Ub-HIST1H2AG [nucleoplasm] (Canis familiaris)
        
        H2AC15 [nucleoplasm] (Canis familiaris)
    - UCH proteinases (Canis familiaris)
      - Histone H2A is dubiquitinated by the PR-DUB complex (Canis familiaris)
        
        Ub-histone H2A [nucleoplasm] (Canis familiaris)
        
        Ub-histone HIST1 H2A [nucleoplasm] (Canis familiaris)
        
        Homologues of Ub-HIST1H2AG [nucleoplasm] (Canis familiaris)
        
        H2AC15 [nucleoplasm] (Canis familiaris)
    - Ub-specific processing proteases (Canis familiaris)
      - USP16,USP21 deubiquitinate Histone H2A (Canis familiaris)
        
        USP16,USP21:Ub-histone H2A [nucleoplasm] (Canis familiaris)
        
        Ub-histone H2A [nucleoplasm] (Canis familiaris)
        
        Ub-histone HIST1 H2A [nucleoplasm] (Canis familiaris)
        
        Homologues of Ub-HIST1H2AG [nucleoplasm] (Canis familiaris)
        
        H2AC15 [nucleoplasm] (Canis familiaris)
      - USP3,SAGA deubiquitinate Histone H2A,H2B (Canis familiaris)
        
        USP3,SAGA:Ub-histone H2A, Ub-histone H2B [nucleoplasm] (Canis familiaris)
        
        Ub-histone H2A, Ub-histone H2B [nucleoplasm] (Canis familiaris)
        
        Ub-histone H2A [nucleoplasm] (Canis familiaris)
        
        Ub-histone HIST1 H2A [nucleoplasm] (Canis familiaris)
        
        Homologues of Ub-HIST1H2AG [nucleoplasm] (Canis familiaris)
        
        H2AC15 [nucleoplasm] (Canis familiaris)

External Reference Information

External Reference

UniProt:A0A5F4CIE3

Gene Names

H2AC15

Reference Genes

BioGPS Gene:106558234 H2AC15

BioGPS Gene:488262 H2AC15

BioGPS Gene:488308 H2AC15

ENSEMBL:ENSCAFG00000028830

ENSEMBL_canis_lupus_familiaris_GENE:ENSCAFG00000044066.2 H2AC15

ENSEMBL_canis_lupus_familiaris_GENE:ENSCAFG00000054022.1 H2AC15

ENSEMBL_canis_lupus_familiaris_GENE:ENSCAFG00000054263.1 H2AC15

ENSEMBL_canis_lupus_familiaris_GENE:ENSCAFG00000055548.1 H2AC15

ENSEMBL_canis_lupus_familiaris_GENE:ENSCAFG00000056824.1 H2AC15

ENSEMBL_canis_lupus_familiaris_GENE:ENSCAFG00000058744.1 H2AC15

ENSEMBL_canis_lupus_familiaris_GENE:ENSCAFG00845015983.1 H2AC15

ENSEMBL_canis_lupus_familiaris_GENE:ENSCAFG00845025509.1 H2AC15

ENSEMBL_canis_lupus_familiaris_GENE:ENSCAFG00845026022.1 H2AC15

ENSEMBL_canis_lupus_familiaris_GENE:ENSCAFG00845026304.1 H2AC15

Monarch:106558234 H2AC15

Monarch:488262 H2AC15

Monarch:488308 H2AC15

NCBI Gene:106558234 H2AC15

NCBI Gene:488262 H2AC15

NCBI Gene:488308 H2AC15

Other Identifiers

100856200

106558234

119867706

119867707

488262

488291

488308

CfaAffx.945.1.S1_s_at

Participates

as a member of

Homologues of Ub-HIST1H2AG [nucleoplasm] (Canis familiaris)

Other forms of this molecule

H2AC15 [nucleoplasm]

Inferred From

Ub-HIST1H2AG [nucleoplasm] (Homo sapiens)

Modified Residues

Name

ubiquitinylated lysine (monoUb [nucleoplasm]) at 120 (in Homo sapiens)

Coordinate

120

Modification

monoUb [nucleoplasm]

PsiMod Name

ubiquitinylated lysine [MOD:01148]

PsiMod Definition

A protein modification that effectively crosslinks the N6-amino of a peptidyl lysine with the carboxyl-terminal glycine of a ubiquitin.

Cross References

OpenTargets

ENSG00000275221

Ensembl

ENSCAFT00845045023, ENSCAFT00845046388, ENSCAFG00845026022, ENSCAFG00845015983, ENSCAFT00845028420, ENSCAFP00845036427, ENSCAFT00845045912, ENSCAFG00845025509, ENSCAFG00845026304, ENSCAFP00845022357, ENSCAFP00845036044, ENSCAFP00845035289