Reactome | INTS13 [nucleoplasm]

INTS13 [nucleoplasm]

Stable Identifier

R-CFA-6807447

Type

Protein [EntityWithAccessionedSequence]

Species

Canis familiaris

Compartment

nucleoplasm

Synonyms

ASUN, A0A8I3PKX4

Locations in the PathwayBrowser

Expand all

Gene expression (Transcription) (Canis familiaris)

- RNA Polymerase II Transcription (Canis familiaris)
  - RNA polymerase II transcribes snRNA genes (Canis familiaris)
    - CBCAP complex binds 7-methylguanosine cap of snRNA (Canis familiaris)
      - RNA polymerase II (phosphoserine-2,7):RPAP2:Integrator:LEC:CBCAP:capped pre-snRNA:Initiation factors:snRNA gene [nucleoplasm] (Canis familiaris)
        
        RNA polymerase II (phospho-Ser2,7 CTD):RPRD1A,B:RPRD2:RPAP2:Integrator:LEC [nucleoplasm] (Canis familiaris)
        
        Integrator [nucleoplasm] (Canis familiaris)
        
        INTS13 [nucleoplasm] (Canis familiaris)
      - RNA polymerase II (phosphoserine-2,7):RPAP2:Integrator:LEC:capped pre-snRNA:Initiation factors:snRNA gene [nucleoplasm] (Canis familiaris)
        
        RNA polymerase II (phospho-Ser2,7 CTD):RPRD1A,B:RPRD2:RPAP2:Integrator:LEC [nucleoplasm] (Canis familiaris)
        
        Integrator [nucleoplasm] (Canis familiaris)
        
        INTS13 [nucleoplasm] (Canis familiaris)
    - Integrator complex processes the 3' end of snRNA (Canis familiaris)
      - Integrator [nucleoplasm] (Canis familiaris)
        
        INTS13 [nucleoplasm] (Canis familiaris)
      - RNA polymerase II (phosphoserine-2,7):RPAP2:Integrator:LEC:CBCAP:capped pre-snRNA:Initiation factors:snRNA gene [nucleoplasm] (Canis familiaris)
        
        RNA polymerase II (phospho-Ser2,7 CTD):RPRD1A,B:RPRD2:RPAP2:Integrator:LEC [nucleoplasm] (Canis familiaris)
        
        Integrator [nucleoplasm] (Canis familiaris)
        
        INTS13 [nucleoplasm] (Canis familiaris)
      - RNA polymerase II (phosphoserine-2,7):RPAP2:Integrator:LEC:Initiation factors:snRNA gene [nucleoplasm] (Canis familiaris)
        
        RNA polymerase II (phospho-Ser2,7 CTD):RPRD1A,B:RPRD2:RPAP2:Integrator:LEC [nucleoplasm] (Canis familiaris)
        
        Integrator [nucleoplasm] (Canis familiaris)
        
        INTS13 [nucleoplasm] (Canis familiaris)
    - Pre-snRNA is elongated and capped with 7-methylguanosine (Canis familiaris)
      - RNA polymerase II (phosphoserine-2,7):RPAP2:Integrator:LEC:capped pre-snRNA:Initiation factors:snRNA gene [nucleoplasm] (Canis familiaris)
        
        RNA polymerase II (phospho-Ser2,7 CTD):RPRD1A,B:RPRD2:RPAP2:Integrator:LEC [nucleoplasm] (Canis familiaris)
        
        Integrator [nucleoplasm] (Canis familiaris)
        
        INTS13 [nucleoplasm] (Canis familiaris)
      - RNA polymerase II (phosphoserine-5,7):RPRD1A,B:RPRD2:RPAP2:Integrator:LEC:pre-snRNA:Initiation factors:snRNA gene [nucleoplasm] (Canis familiaris)
        
        RNA polymerase II (phospho-Ser5,7 CTD):RDRP1A,B:RDRP2:RPAP2:Integrator:LEC [nucleoplasm] (Canis familiaris)
        
        Integrator [nucleoplasm] (Canis familiaris)
        
        INTS13 [nucleoplasm] (Canis familiaris)
    - Pre-snRNA transcript initiation, Integrator binding, LEC binding (Canis familiaris)
      - Integrator [nucleoplasm] (Canis familiaris)
        
        INTS13 [nucleoplasm] (Canis familiaris)
      - RNA polymerase II (phosphoserine-5,7):RPRD1A,B:RPRD2:RPAP2:Integrator:LEC:pre-snRNA:Initiation factors:snRNA gene [nucleoplasm] (Canis familiaris)
        
        RNA polymerase II (phospho-Ser5,7 CTD):RDRP1A,B:RDRP2:RPAP2:Integrator:LEC [nucleoplasm] (Canis familiaris)
        
        Integrator [nucleoplasm] (Canis familiaris)
        
        INTS13 [nucleoplasm] (Canis familiaris)

External Reference Information

External Reference

UniProt:A0A8I3PKX4

Gene Names

INTS13

Reference Genes

ENSEMBL:ENSCAFG00845025493.1

ENSEMBL_canis_lupus_familiaris_GENE:ENSCAFG00845025493.1 INTS13

Other Identifiers

486627

CfaAffx.17545.1.S1_at

GO:0000278

GO:0005634

GO:0005654

GO:0005737

GO:0007010

GO:0007052

GO:0007346

GO:0016604

GO:0043226

GO:0043231

GO:0051642

GO:0090435

Participates

as a component of

Integrator [nucleoplasm] (Canis familiaris)

Inferred From

ASUN [nucleoplasm] (Homo sapiens)

Cross References

OpenTargets

ENSG00000064102

Ensembl

ENSCAFG00845025493, ENSCAFP00845035278, ENSCAFT00845045011