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ORC3 [nucleoplasm]
Stable Identifier
R-CFA-68513
Type
Protein [EntityWithAccessionedSequence]
Species
Canis familiaris
Compartment
nucleoplasm
Synonyms
ORC3, A0A8I3N1D9
Locations in the PathwayBrowser
Expand all
Cell Cycle (Canis familiaris)
Cell Cycle Checkpoints (Canis familiaris)
G2/M Checkpoints (Canis familiaris)
Activation of ATR in response to replication stress (Canis familiaris)
Activation of claspin (Canis familiaris)
Cdc45:CDK:DDK:Mcm10:Activated claspin:pre-replicative complex [nucleoplasm] (Canis familiaris)
CDK:DDK:MCM10:active pre-replicative complex:CDC45 [nucleoplasm] (Canis familiaris)
CDK:DDK:MCM10:active pre-replicative complex [nucleoplasm] (Canis familiaris)
MCM10:active pre-replicative complex [nucleoplasm] (Canis familiaris)
active pre-replicative complex [nucleoplasm] (Canis familiaris)
CDC6:ORC:origin complex [nucleoplasm] (Canis familiaris)
ORC:origin of replication [nucleoplasm] (Canis familiaris)
ORC3 [nucleoplasm] (Canis familiaris)
Cdc45:CDK:DDK:Mcm10:claspin:pre-replicative complex [nucleoplasm] (Canis familiaris)
CDK:DDK:MCM10:active pre-replicative complex:CDC45 [nucleoplasm] (Canis familiaris)
CDK:DDK:MCM10:active pre-replicative complex [nucleoplasm] (Canis familiaris)
MCM10:active pre-replicative complex [nucleoplasm] (Canis familiaris)
active pre-replicative complex [nucleoplasm] (Canis familiaris)
CDC6:ORC:origin complex [nucleoplasm] (Canis familiaris)
ORC:origin of replication [nucleoplasm] (Canis familiaris)
ORC3 [nucleoplasm] (Canis familiaris)
Loading of claspin onto DNA during replication origin firing (Canis familiaris)
CDK:DDK:MCM10:active pre-replicative complex:CDC45 [nucleoplasm] (Canis familiaris)
CDK:DDK:MCM10:active pre-replicative complex [nucleoplasm] (Canis familiaris)
MCM10:active pre-replicative complex [nucleoplasm] (Canis familiaris)
active pre-replicative complex [nucleoplasm] (Canis familiaris)
CDC6:ORC:origin complex [nucleoplasm] (Canis familiaris)
ORC:origin of replication [nucleoplasm] (Canis familiaris)
ORC3 [nucleoplasm] (Canis familiaris)
Cdc45:CDK:DDK:Mcm10:claspin:pre-replicative complex [nucleoplasm] (Canis familiaris)
CDK:DDK:MCM10:active pre-replicative complex:CDC45 [nucleoplasm] (Canis familiaris)
CDK:DDK:MCM10:active pre-replicative complex [nucleoplasm] (Canis familiaris)
MCM10:active pre-replicative complex [nucleoplasm] (Canis familiaris)
active pre-replicative complex [nucleoplasm] (Canis familiaris)
CDC6:ORC:origin complex [nucleoplasm] (Canis familiaris)
ORC:origin of replication [nucleoplasm] (Canis familiaris)
ORC3 [nucleoplasm] (Canis familiaris)
Cell Cycle, Mitotic (Canis familiaris)
Mitotic G1 phase and G1/S transition (Canis familiaris)
G1/S Transition (Canis familiaris)
Activation of the pre-replicative complex (Canis familiaris)
Cdc45 associates with the pre-replicative complex at the origin (Canis familiaris)
CDK:DDK:MCM10:active pre-replicative complex [nucleoplasm] (Canis familiaris)
MCM10:active pre-replicative complex [nucleoplasm] (Canis familiaris)
active pre-replicative complex [nucleoplasm] (Canis familiaris)
CDC6:ORC:origin complex [nucleoplasm] (Canis familiaris)
ORC:origin of replication [nucleoplasm] (Canis familiaris)
ORC3 [nucleoplasm] (Canis familiaris)
CDK:DDK:MCM10:active pre-replicative complex:CDC45 [nucleoplasm] (Canis familiaris)
CDK:DDK:MCM10:active pre-replicative complex [nucleoplasm] (Canis familiaris)
MCM10:active pre-replicative complex [nucleoplasm] (Canis familiaris)
active pre-replicative complex [nucleoplasm] (Canis familiaris)
CDC6:ORC:origin complex [nucleoplasm] (Canis familiaris)
ORC:origin of replication [nucleoplasm] (Canis familiaris)
ORC3 [nucleoplasm] (Canis familiaris)
Cdt1 is displaced from the pre-replicative complex. (Canis familiaris)
MCM10:active pre-replicative complex [nucleoplasm] (Canis familiaris)
active pre-replicative complex [nucleoplasm] (Canis familiaris)
CDC6:ORC:origin complex [nucleoplasm] (Canis familiaris)
ORC:origin of replication [nucleoplasm] (Canis familiaris)
ORC3 [nucleoplasm] (Canis familiaris)
MCM10:pre-replicative complex [nucleoplasm] (Canis familiaris)
pre-replicative complex [nucleoplasm] (Canis familiaris)
CDT1:CDC6:ORC:origin complex [nucleoplasm] (Canis familiaris)
CDC6:ORC:origin complex [nucleoplasm] (Canis familiaris)
ORC:origin of replication [nucleoplasm] (Canis familiaris)
ORC3 [nucleoplasm] (Canis familiaris)
DNA Replication Factor A (RPA) associates with the pre-replicative complex at the origin (Canis familiaris)
CDK:DDK:MCM10:active pre-replicative complex:CDC45 [nucleoplasm] (Canis familiaris)
CDK:DDK:MCM10:active pre-replicative complex [nucleoplasm] (Canis familiaris)
MCM10:active pre-replicative complex [nucleoplasm] (Canis familiaris)
active pre-replicative complex [nucleoplasm] (Canis familiaris)
CDC6:ORC:origin complex [nucleoplasm] (Canis familiaris)
ORC:origin of replication [nucleoplasm] (Canis familiaris)
ORC3 [nucleoplasm] (Canis familiaris)
CDK:DDK:MCM10:active pre-replicative complex:CDC45:RPA1-4 [nucleoplasm] (Canis familiaris)
CDK:DDK:MCM10:active pre-replicative complex:CDC45 [nucleoplasm] (Canis familiaris)
CDK:DDK:MCM10:active pre-replicative complex [nucleoplasm] (Canis familiaris)
MCM10:active pre-replicative complex [nucleoplasm] (Canis familiaris)
active pre-replicative complex [nucleoplasm] (Canis familiaris)
CDC6:ORC:origin complex [nucleoplasm] (Canis familiaris)
ORC:origin of replication [nucleoplasm] (Canis familiaris)
ORC3 [nucleoplasm] (Canis familiaris)
DNA polymerase alpha:primase binds at the origin (Canis familiaris)
CDK:DDK:MCM10:active pre-replicative complex:CDC45:RPA1-4 [nucleoplasm] (Canis familiaris)
CDK:DDK:MCM10:active pre-replicative complex:CDC45 [nucleoplasm] (Canis familiaris)
CDK:DDK:MCM10:active pre-replicative complex [nucleoplasm] (Canis familiaris)
MCM10:active pre-replicative complex [nucleoplasm] (Canis familiaris)
active pre-replicative complex [nucleoplasm] (Canis familiaris)
CDC6:ORC:origin complex [nucleoplasm] (Canis familiaris)
ORC:origin of replication [nucleoplasm] (Canis familiaris)
ORC3 [nucleoplasm] (Canis familiaris)
DNA polymerase epsilon binds at the origin (Canis familiaris)
CDK:DDK:MCM10:active pre-replicative complex:CDC45:RPA1-4 [nucleoplasm] (Canis familiaris)
CDK:DDK:MCM10:active pre-replicative complex:CDC45 [nucleoplasm] (Canis familiaris)
CDK:DDK:MCM10:active pre-replicative complex [nucleoplasm] (Canis familiaris)
MCM10:active pre-replicative complex [nucleoplasm] (Canis familiaris)
active pre-replicative complex [nucleoplasm] (Canis familiaris)
CDC6:ORC:origin complex [nucleoplasm] (Canis familiaris)
ORC:origin of replication [nucleoplasm] (Canis familiaris)
ORC3 [nucleoplasm] (Canis familiaris)
S Phase (Canis familiaris)
Synthesis of DNA (Canis familiaris)
Switching of origins to a post-replicative state (Canis familiaris)
Orc1 removal from chromatin (Canis familiaris)
Orc1 is phosphorylated by cyclin A/CDK2 (Canis familiaris)
pre-replicative complex (Orc1-minus) [nucleoplasm] (Canis familiaris)
ORC3 [nucleoplasm] (Canis familiaris)
pre-replicative complex [nucleoplasm] (Canis familiaris)
CDT1:CDC6:ORC:origin complex [nucleoplasm] (Canis familiaris)
CDC6:ORC:origin complex [nucleoplasm] (Canis familiaris)
ORC:origin of replication [nucleoplasm] (Canis familiaris)
ORC3 [nucleoplasm] (Canis familiaris)
DNA Replication (Canis familiaris)
DNA Replication Pre-Initiation (Canis familiaris)
Activation of the pre-replicative complex (Canis familiaris)
Cdc45 associates with the pre-replicative complex at the origin (Canis familiaris)
CDK:DDK:MCM10:active pre-replicative complex [nucleoplasm] (Canis familiaris)
MCM10:active pre-replicative complex [nucleoplasm] (Canis familiaris)
active pre-replicative complex [nucleoplasm] (Canis familiaris)
CDC6:ORC:origin complex [nucleoplasm] (Canis familiaris)
ORC:origin of replication [nucleoplasm] (Canis familiaris)
ORC3 [nucleoplasm] (Canis familiaris)
CDK:DDK:MCM10:active pre-replicative complex:CDC45 [nucleoplasm] (Canis familiaris)
CDK:DDK:MCM10:active pre-replicative complex [nucleoplasm] (Canis familiaris)
MCM10:active pre-replicative complex [nucleoplasm] (Canis familiaris)
active pre-replicative complex [nucleoplasm] (Canis familiaris)
CDC6:ORC:origin complex [nucleoplasm] (Canis familiaris)
ORC:origin of replication [nucleoplasm] (Canis familiaris)
ORC3 [nucleoplasm] (Canis familiaris)
Cdt1 is displaced from the pre-replicative complex. (Canis familiaris)
MCM10:active pre-replicative complex [nucleoplasm] (Canis familiaris)
active pre-replicative complex [nucleoplasm] (Canis familiaris)
CDC6:ORC:origin complex [nucleoplasm] (Canis familiaris)
ORC:origin of replication [nucleoplasm] (Canis familiaris)
ORC3 [nucleoplasm] (Canis familiaris)
MCM10:pre-replicative complex [nucleoplasm] (Canis familiaris)
pre-replicative complex [nucleoplasm] (Canis familiaris)
CDT1:CDC6:ORC:origin complex [nucleoplasm] (Canis familiaris)
CDC6:ORC:origin complex [nucleoplasm] (Canis familiaris)
ORC:origin of replication [nucleoplasm] (Canis familiaris)
ORC3 [nucleoplasm] (Canis familiaris)
DNA Replication Factor A (RPA) associates with the pre-replicative complex at the origin (Canis familiaris)
CDK:DDK:MCM10:active pre-replicative complex:CDC45 [nucleoplasm] (Canis familiaris)
CDK:DDK:MCM10:active pre-replicative complex [nucleoplasm] (Canis familiaris)
MCM10:active pre-replicative complex [nucleoplasm] (Canis familiaris)
active pre-replicative complex [nucleoplasm] (Canis familiaris)
CDC6:ORC:origin complex [nucleoplasm] (Canis familiaris)
ORC:origin of replication [nucleoplasm] (Canis familiaris)
ORC3 [nucleoplasm] (Canis familiaris)
CDK:DDK:MCM10:active pre-replicative complex:CDC45:RPA1-4 [nucleoplasm] (Canis familiaris)
CDK:DDK:MCM10:active pre-replicative complex:CDC45 [nucleoplasm] (Canis familiaris)
CDK:DDK:MCM10:active pre-replicative complex [nucleoplasm] (Canis familiaris)
MCM10:active pre-replicative complex [nucleoplasm] (Canis familiaris)
active pre-replicative complex [nucleoplasm] (Canis familiaris)
CDC6:ORC:origin complex [nucleoplasm] (Canis familiaris)
ORC:origin of replication [nucleoplasm] (Canis familiaris)
ORC3 [nucleoplasm] (Canis familiaris)
DNA polymerase alpha:primase binds at the origin (Canis familiaris)
CDK:DDK:MCM10:active pre-replicative complex:CDC45:RPA1-4 [nucleoplasm] (Canis familiaris)
CDK:DDK:MCM10:active pre-replicative complex:CDC45 [nucleoplasm] (Canis familiaris)
CDK:DDK:MCM10:active pre-replicative complex [nucleoplasm] (Canis familiaris)
MCM10:active pre-replicative complex [nucleoplasm] (Canis familiaris)
active pre-replicative complex [nucleoplasm] (Canis familiaris)
CDC6:ORC:origin complex [nucleoplasm] (Canis familiaris)
ORC:origin of replication [nucleoplasm] (Canis familiaris)
ORC3 [nucleoplasm] (Canis familiaris)
DNA polymerase epsilon binds at the origin (Canis familiaris)
CDK:DDK:MCM10:active pre-replicative complex:CDC45:RPA1-4 [nucleoplasm] (Canis familiaris)
CDK:DDK:MCM10:active pre-replicative complex:CDC45 [nucleoplasm] (Canis familiaris)
CDK:DDK:MCM10:active pre-replicative complex [nucleoplasm] (Canis familiaris)
MCM10:active pre-replicative complex [nucleoplasm] (Canis familiaris)
active pre-replicative complex [nucleoplasm] (Canis familiaris)
CDC6:ORC:origin complex [nucleoplasm] (Canis familiaris)
ORC:origin of replication [nucleoplasm] (Canis familiaris)
ORC3 [nucleoplasm] (Canis familiaris)
Assembly of the pre-replicative complex (Canis familiaris)
Assembly of the ORC complex at the origin of replication (Canis familiaris)
Formation of ORC(1-5) complex (Canis familiaris)
ORC(1-5):origin of replication [nucleoplasm] (Canis familiaris)
ORC(1-5) [nucleoplasm] (Canis familiaris)
ORC(2-5) [nucleoplasm] (Canis familiaris)
ORC2:ORC3:ORC5 [nucleoplasm] (Canis familiaris)
ORC2:ORC3 [nucleoplasm] (Canis familiaris)
ORC3 [nucleoplasm] (Canis familiaris)
ORC(2-5) [nucleoplasm] (Canis familiaris)
ORC2:ORC3:ORC5 [nucleoplasm] (Canis familiaris)
ORC2:ORC3 [nucleoplasm] (Canis familiaris)
ORC3 [nucleoplasm] (Canis familiaris)
Formation of ORC(1-6) complex (Canis familiaris)
ORC(1-5):origin of replication [nucleoplasm] (Canis familiaris)
ORC(1-5) [nucleoplasm] (Canis familiaris)
ORC(2-5) [nucleoplasm] (Canis familiaris)
ORC2:ORC3:ORC5 [nucleoplasm] (Canis familiaris)
ORC2:ORC3 [nucleoplasm] (Canis familiaris)
ORC3 [nucleoplasm] (Canis familiaris)
ORC(1-6):origin of replication [nucleoplasm] (Canis familiaris)
ORC(1-5):origin of replication [nucleoplasm] (Canis familiaris)
ORC(1-5) [nucleoplasm] (Canis familiaris)
ORC(2-5) [nucleoplasm] (Canis familiaris)
ORC2:ORC3:ORC5 [nucleoplasm] (Canis familiaris)
ORC2:ORC3 [nucleoplasm] (Canis familiaris)
ORC3 [nucleoplasm] (Canis familiaris)
Formation of ORC(2-5) complex (Canis familiaris)
ORC(2-5) [nucleoplasm] (Canis familiaris)
ORC2:ORC3:ORC5 [nucleoplasm] (Canis familiaris)
ORC2:ORC3 [nucleoplasm] (Canis familiaris)
ORC3 [nucleoplasm] (Canis familiaris)
ORC2:ORC3:ORC5 [nucleoplasm] (Canis familiaris)
ORC2:ORC3 [nucleoplasm] (Canis familiaris)
ORC3 [nucleoplasm] (Canis familiaris)
ORC2 binds ORC3 (Canis familiaris)
ORC2:ORC3 [nucleoplasm] (Canis familiaris)
ORC3 [nucleoplasm] (Canis familiaris)
ORC3 [nucleoplasm] (Canis familiaris)
ORC5 binds ORC2:ORC3 (Canis familiaris)
ORC2:ORC3 [nucleoplasm] (Canis familiaris)
ORC3 [nucleoplasm] (Canis familiaris)
ORC2:ORC3:ORC5 [nucleoplasm] (Canis familiaris)
ORC2:ORC3 [nucleoplasm] (Canis familiaris)
ORC3 [nucleoplasm] (Canis familiaris)
CDC6 association with the ORC:origin complex (Canis familiaris)
CDC6 association with ORC(1-6) at replication origins (Canis familiaris)
ORC(1-6):CDC6:origin of replication [nucleoplasm] (Canis familiaris)
ORC(1-6):origin of replication [nucleoplasm] (Canis familiaris)
ORC(1-5):origin of replication [nucleoplasm] (Canis familiaris)
ORC(1-5) [nucleoplasm] (Canis familiaris)
ORC(2-5) [nucleoplasm] (Canis familiaris)
ORC2:ORC3:ORC5 [nucleoplasm] (Canis familiaris)
ORC2:ORC3 [nucleoplasm] (Canis familiaris)
ORC3 [nucleoplasm] (Canis familiaris)
ORC(1-6):origin of replication [nucleoplasm] (Canis familiaris)
ORC(1-5):origin of replication [nucleoplasm] (Canis familiaris)
ORC(1-5) [nucleoplasm] (Canis familiaris)
ORC(2-5) [nucleoplasm] (Canis familiaris)
ORC2:ORC3:ORC5 [nucleoplasm] (Canis familiaris)
ORC2:ORC3 [nucleoplasm] (Canis familiaris)
ORC3 [nucleoplasm] (Canis familiaris)
Synthesis of DNA (Canis familiaris)
Switching of origins to a post-replicative state (Canis familiaris)
Orc1 removal from chromatin (Canis familiaris)
Orc1 is phosphorylated by cyclin A/CDK2 (Canis familiaris)
pre-replicative complex (Orc1-minus) [nucleoplasm] (Canis familiaris)
ORC3 [nucleoplasm] (Canis familiaris)
pre-replicative complex [nucleoplasm] (Canis familiaris)
CDT1:CDC6:ORC:origin complex [nucleoplasm] (Canis familiaris)
CDC6:ORC:origin complex [nucleoplasm] (Canis familiaris)
ORC:origin of replication [nucleoplasm] (Canis familiaris)
ORC3 [nucleoplasm] (Canis familiaris)
External Reference Information
External Reference
UniProt:A0A8I3N1D9
Gene Names
ORC3
Reference Genes
ENSEMBL:ENSCAFG00845005944.1
ENSEMBL_canis_lupus_familiaris_GENE:ENSCAFG00845005944.1 ORC3
Other Identifiers
474991
Cfa.18996.1.S1_s_at
Cfa.224.1.A1_at
CfaAffx.5563.1.S1_at
GO:0000228
GO:0000785
GO:0000808
GO:0003677
GO:0005634
GO:0005654
GO:0005664
GO:0005694
GO:0006260
GO:0006270
GO:0006275
GO:0014009
GO:0016604
GO:0030154
GO:0043226
GO:0048856
GO:0061351
Participates
as a component of
pre-replicative complex (Orc1-minus) [nucleoplasm] (Canis familiaris)
ORC2:ORC3 [nucleoplasm] (Canis familiaris)
ORC:origin of replication [nucleoplasm] (Canis familiaris)
as an input of
ORC2 binds ORC3 (Canis familiaris)
Inferred From
ORC3 [nucleoplasm]
(Homo sapiens)
Cross References
OpenTargets
ENSG00000135336
Ensembl
ENSCAFP00845008183
,
ENSCAFT00845010520
,
ENSCAFG00845005944
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