Reactome | MDM2 [nucleoplasm]

MDM2 [nucleoplasm]

Stable Identifier

R-CFA-69486

Type

Protein [EntityWithAccessionedSequence]

Species

Canis familiaris

Compartment

nucleoplasm

Synonyms

F1PGL9

Locations in the PathwayBrowser

Expand all

Gene expression (Transcription) (Canis familiaris)

- RNA Polymerase II Transcription (Canis familiaris)
  - Generic Transcription Pathway (Canis familiaris)
    - Transcriptional Regulation by TP53 (Canis familiaris)
      - Regulation of TP53 Activity (Canis familiaris)
        
        Regulation of TP53 Expression and Degradation (Canis familiaris)
        
        Regulation of TP53 Degradation (Canis familiaris)
        
        MDM2 translocates to the cytosol (Canis familiaris)
        
        MDM2 [nucleoplasm] (Canis familiaris)

External Reference Information

External Reference

UniProt:F1PGL9

Reference Genes

ENSEMBL:ENSCAFG00000000418

Other Identifiers

403693

AAEX03007044

AAEX03007045

CfaAffx.1587.1.S1_s_at

ENSCAFG00000000418

ENSCAFP00000000608

ENSCAFT00000000663

EntrezGene:403693

EntrezGene:MDM2

GO:0000122

GO:0000278

GO:0001568

GO:0001974

GO:0002027

GO:0002039

GO:0003013

GO:0003170

GO:0003181

GO:0003203

GO:0003281

GO:0003283

GO:0003674

GO:0003723

GO:0004842

GO:0005515

GO:0005575

GO:0005622

GO:0005623

GO:0005634

GO:0005654

GO:0005730

GO:0005737

GO:0006464

GO:0006511

GO:0006950

GO:0006977

GO:0007049

GO:0007089

GO:0007165

GO:0007507

GO:0008097

GO:0008150

GO:0008219

GO:0008270

GO:0009056

GO:0009058

GO:0010468

GO:0016567

GO:0016604

GO:0016874

GO:0018205

GO:0019843

GO:0019899

GO:0019904

GO:0022607

GO:0031625

GO:0031648

GO:0032182

GO:0032436

GO:0032991

GO:0034504

GO:0034641

GO:0042176

GO:0042802

GO:0043021

GO:0043066

GO:0043130

GO:0043167

GO:0043226

GO:0043518

GO:0045184

GO:0045787

GO:0045892

GO:0045931

GO:0046677

GO:0046872

GO:0047485

GO:0048856

GO:0051603

GO:0051865

GO:0060411

GO:0061630

GO:0061663

GO:0065003

GO:0071157

GO:0071456

GO:0071480

GO:0072717

GO:0097110

GO:0097718

GO:1901797

GO:1902254

GO:1990000

IPR001876

IPR003121

IPR013083

IPR015459

IPR016495

IPR028340

IPR036443

IPR036885

MDM2

MDM2-201

NM_001003103

NP_001003103

PF00641

PF02201

PF13920

UPI000274A50A

VGNC:43106

XM_005625450

XM_005625451

XP_005625507

XP_005625508

Participant Of

hasMember

TP53,MDM2,MDM4,FOXO4,PTEN [nucleoplasm]

input

Other forms of this molecule

PolyUb-MDM2 [nucleoplasm]

SUMO1-K182-MDM2 [nucleoplasm]

MDM2 [plasma membrane]

MDM2 [endocytic vesicle membrane]

phospho-p-S166,S188,T218-MDM2 [nucleoplasm]

phospho-p-5S,T-MDM2 [nucleoplasm]

phospho-PolyUb,p-S166,S188-MDM2 [nucleoplasm]

MDM2 [cytosol]

phospho-p-S166,S188-MDM2 [cytosol]

phospho-p-S166,S188-MDM2 [nucleoplasm]

Inferred From

MDM2 [nucleoplasm] (Homo sapiens)