Reactome | MDM2 [nucleoplasm]

MDM2 [nucleoplasm]

Stable Identifier

R-CFA-69486

Type

Protein [EntityWithAccessionedSequence]

Species

Canis familiaris

Compartment

nucleoplasm

Synonyms

MDM2, F1PGL9

Locations in the PathwayBrowser

Expand all

Gene expression (Transcription) (Canis familiaris)

- RNA Polymerase II Transcription (Canis familiaris)
  - Generic Transcription Pathway (Canis familiaris)
    - Transcriptional Regulation by TP53 (Canis familiaris)
      - Regulation of TP53 Activity (Canis familiaris)
        
        Regulation of TP53 Expression and Degradation (Canis familiaris)
        
        Regulation of TP53 Degradation (Canis familiaris)
        
        MDM2 translocates to the cytosol (Canis familiaris)
        
        MDM2 [nucleoplasm] (Canis familiaris)

External Reference Information

External Reference

UniProt:F1PGL9

Gene Names

MDM2

Reference Genes

ENSEMBL:ENSCAFG00000000418

Other Identifiers

403693

CfaAffx.1587.1.S1_at

CfaAffx.1587.1.S1_s_at

ENSCAFG00000000418

ENSCAFP00000000608

ENSCAFT00000000663

EntrezGene:403693

EntrezGene:MDM2

GO:0000122

GO:0003674

GO:0005515

GO:0005575

GO:0005622

GO:0005623

GO:0005634

GO:0006464

GO:0007049

GO:0008150

GO:0008219

GO:0009058

GO:0016567

GO:0034641

GO:0043066

GO:0043167

GO:0043226

GO:0046872

GO:0071157

IPR001841

IPR001876

IPR003121

IPR013083

IPR015459

IPR016495

IPR028340

IPR036443

IPR036885

MDM2

MDM2-208

PF00641

PF02201

PF13920

VGNC:43106

Participant Of

hasMember

TP53,MDM2,MDM4,FOXO4,PTEN [nucleoplasm]

input

Other forms of this molecule

MDM2 [nucleoplasm]

phospho-MDM2 [nucleoplasm]

MDM2 [plasma membrane]

MDM2 [endocytic vesicle membrane]

phospho-MDM2 [nucleoplasm]

MDM2 [cytosol]

phospho-MDM2 [cytosol]

phospho-MDM2 [nucleoplasm]

Inferred From

MDM2 [nucleoplasm] (Homo sapiens)

Cross References

OpenTargets

ENSG00000135679

Ensembl

ENSCAFT00000000663, ENSCAFG00000000418, ENSCAFP00000000608

VGNC

43106