Reactome | Ub,p-T,S-SMAD2/3 [nucleoplasm]

Ub,p-T,S-SMAD2/3 [nucleoplasm]

Stable Identifier

R-CFA-9773846

Type

Set [DefinedSet]

Species

Canis familiaris

Compartment

nucleoplasm

Locations in the PathwayBrowser

Expand all

Gene expression (Transcription) (Canis familiaris)

- RNA Polymerase II Transcription (Canis familiaris)
  - Generic Transcription Pathway (Canis familiaris)
    - Transcriptional activity of SMAD2/SMAD3:SMAD4 heterotrimer (Canis familiaris)
      - Downregulation of SMAD2/3:SMAD4 transcriptional activity (Canis familiaris)
        
        SMURF2 monoubiquitinates SMAD3 (Canis familiaris)
        
        Ub,p-T,S-SMAD2/3 [nucleoplasm] (Canis familiaris)

Signal Transduction (Canis familiaris)

- Signaling by TGFB family members (Canis familiaris)
  - Signaling by TGF-beta Receptor Complex (Canis familiaris)
    - Transcriptional activity of SMAD2/SMAD3:SMAD4 heterotrimer (Canis familiaris)
      - Downregulation of SMAD2/3:SMAD4 transcriptional activity (Canis familiaris)
        
        SMURF2 monoubiquitinates SMAD3 (Canis familiaris)
        
        Ub,p-T,S-SMAD2/3 [nucleoplasm] (Canis familiaris)

Participants

members

Participates

as an output of

SMURF2 monoubiquitinates SMAD3 (Canis familiaris)

Inferred From

Ub,p-T,S-SMAD2/3 [nucleoplasm] (Homo sapiens)

© 2024 Reactome

Cite Us!