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pp1ab-nsp10 [cytosol]
Stable Identifier
R-COV-9682216
Type
Protein [EntityWithAccessionedSequence]
Species
Human SARS coronavirus
Compartment
cytosol
Synonyms
nsp10, Non-structural protein 10, rep (4231–4369)
Locations in the PathwayBrowser for interactor UniProt:P0C6X7
Expand all
Disease (Homo sapiens)
Infectious disease (Homo sapiens)
Viral Infection Pathways (Homo sapiens)
SARS-CoV Infections (Homo sapiens)
SARS-CoV-1 Infection (Homo sapiens)
Translation of Replicase and Assembly of the Replication Transcription Complex (Homo sapiens)
Maturation of replicase proteins (Homo sapiens)
3CLp cleaves pp1ab (Homo sapiens)
pp1ab-nsp10 [cytosol] (Human SARS coronavirus)
External Reference Information
External Reference
UniProt:P0C6X7 rep
Gene Names
rep, 1a-1b
Chain
chain:1-180, chain:181-818, chain:819-2740, chain:2741-3240, chain:3241-3546, chain:3547-3836, chain:3837-3919, chain:3920-4117, chain:4118-4230, chain:4231-4369, chain:4370-5301, chain:5302-5902, chain:5903-6429, chain:6430-6775, chain:6776-7073
Reference Genes
BioGPS Gene:1489680 rep
KEGG Gene (Hepatitis C Virus):1489680 rep
Monarch:1489680 rep
NCBI Gene:1489680 rep
Reference Transcript
RefSeq:NC_004718.3 rep
Participates
as an output of
3CLp cleaves pp1ab (Homo sapiens)
as a member of
nsp10 [cytosol] (Human SARS coronavirus)
Other forms of this molecule
N-glycan pp1ab-nsp4 [endoplasmic reticulum membrane]
N-glycan pp1ab-nsp3 [endoplasmic reticulum membrane]
pp1ab-nsp4 [cytosol]
pp1ab-nsp3 [cytosol]
N-glycan pp1ab-nsp3-4 [endoplasmic reticulum membrane]
pp1ab-nsp9 [cytosol]
pp1ab-nsp6 [endoplasmic reticulum membrane]
pp1ab-nsp5 [cytosol]
pp1ab-nsp2 [cytosol]
pp1ab-nsp3-4 [cytosol]
pp1ab-nsp1 [cytosol]
pp1ab-nsp1-4 [cytosol]
pp1ab [cytosol]
pp1ab-nsp6 [double membrane vesicle viral factory outer membrane]
pp1ab-nsp4 [double membrane vesicle viral factory outer membrane]
pp1ab-nsp3 [double membrane vesicle viral factory outer membrane]
pp1ab-nsp16 [cytosol]
pp1ab-nsp13 [cytosol]
pp1ab-nsp12 [cytosol]
pp1ab-nsp7 [cytosol]
pp1ab-nsp8 [cytosol]
pp1ab-nsp14 [cytosol]
pp1ab-nsp15 [cytosol]
Inferred To
pp1ab-nsp10 [cytosol]
(Severe acute respiratory syndrome coronavirus 2)
Disease
Name
Identifier
Synonyms
severe acute respiratory syndrome
DOID:2945
SARS-CoV infection, SARS
Cross References
RefSeq
NP_828849.2
ZINC - Metabolites
R1AB_CVHSA
ZINC - World Drugs
R1AB_CVHSA
IntEnz
2.1.1.57
,
2.7.7.50
,
3.4.19.12
,
3.6.4.13
,
3.4.22.69
ZINC - Substances
R1AB_CVHSA
ZINC - Biogenic
R1AB_CVHSA
ZINC target
P0C6X7
ZINC - Predictions - Purchasable
R1AB_CVHSA
PDB
5C5O
,
2GT7
,
1WOF
,
2XYV
,
2BX4
,
1UK2
,
6WCO
,
2JZD
,
4WY3
,
6LNQ
,
2GA6
,
1UK4
,
2Z9J
,
5E6J
,
2Z3E
,
5C8S
,
2H2Z
,
2QC2
,
5N5O
,
4TWW
,
5F22
,
2QCY
,
2IDY
,
2C3S
,
5N19
,
2A5K
,
1QZ8
,
2GX4
,
1UW7
,
2A5A
,
1Z1I
,
2FYG
,
3E9S
,
3D62
,
2Z9K
,
5C8T
,
6W79
,
5NFY
,
2Q6G
,
2AMD
,
2GZ8
,
4TWY
,
6NUR
,
2K7X
,
3R24
,
7LCP
,
5B6O
,
2GTB
,
2RHB
,
2QIQ
,
2XYQ
,
4ZUH
,
2K87
,
2Z94
,
1Q2W
,
2JZE
,
2FE8
,
2PWX
,
2JZF
,
1UK3
,
2AMQ
,
5C8U
,
2HSX
,
1YSY
,
2Z9L
,
2GZ9
,
2GZ7
,
2GT8
,
2HOB
,
2Z3C
,
2OZK
,
2XYR
,
2VJ1
,
3EBN
,
2GDT
,
2ACF
,
2BX3
,
2V6N
,
5C5N
,
2OP9
,
2A5I
,
1Z1J
,
2H85
,
2G9T
,
2GRI
,
2Z3D
,
2Z9G
,
6NUS
,
2DUC
,
2D2D
,
2AHM
,
2FAV
,
1UJ1
,
2RNK
,
2ALV
,
6JYT
,
7LCQ
Interactors (2)
Accession
#Entities
Entities
Confidence Score
Evidence (IntAct)
UniProt:P0C6X7 rep
20
N-glycan pp1ab-nsp4 [endoplasmic reticulum membrane]
(R-COV-9684860)
N-glycan pp1ab-nsp3 [endoplasmic reticulum membrane]
(R-COV-9682204)
pp1ab-nsp4 [cytosol]
(R-COV-9684868)
pp1ab-nsp3 [cytosol]
(R-COV-9684867)
N-glycan pp1ab-nsp3-4 [endoplasmic reticulum membrane]
(R-COV-9684874)
pp1ab-nsp9 [cytosol]
(R-COV-9682232)
pp1ab-nsp6 [endoplasmic reticulum membrane]
(R-COV-9682233)
pp1ab-nsp5 [cytosol]
(R-COV-9682196)
pp1ab-nsp2 [cytosol]
(R-COV-9682221)
pp1ab-nsp3-4 [cytosol]
(R-COV-9684864)
pp1ab-nsp1 [cytosol]
(R-COV-9682211)
pp1ab-nsp1-4 [cytosol]
(R-COV-9684861)
pp1ab [cytosol]
(R-COV-9684355)
pp1ab-nsp6 [double membrane vesicle viral factory outer membrane]
(R-COV-9685986)
pp1ab-nsp4 [double membrane vesicle viral factory outer membrane]
(R-COV-9686029)
pp1ab-nsp3 [double membrane vesicle viral factory outer membrane]
(R-COV-9685989)
pp1ab-nsp16 [cytosol]
(R-COV-9678289)
pp1ab-nsp13 [cytosol]
(R-COV-9678281)
pp1ab-nsp12 [cytosol]
(R-COV-9678280)
pp1ab-nsp7 [cytosol]
(R-COV-9682244)
0.676
3
UniProt:O75348 ATP6V1G1
1
ATP6V1G1 [cytosol]
(R-HSA-912578)
0.656
5
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