Reactome | N-glycan M [endoplasmic reticulum membrane]

N-glycan M [endoplasmic reticulum membrane]

Stable Identifier

R-COV-9683588

Type

Protein [EntityWithAccessionedSequence]

Species

Human SARS coronavirus

Compartment

endoplasmic reticulum membrane

Locations in the PathwayBrowser

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Literature References

PubMed ID	Title	Journal	Year
16442106	Characterization of severe acute respiratory syndrome coronavirus membrane protein Voss, D, Kern, A, Traggiai, E, Eickmann, M, Stadler, K, Lanzavecchia, A, Becker, S	FEBS Lett.	2006

External Reference Information

External Reference

UniProt:P59596 M

Gene Names

M, 5

Chain

chain:1-221

Reference Genes

KEGG Gene (Viruses):1489672 M

Participant Of

output

M protein gets N-glycosylated

input

Glycosylated M localizes to the Golgi membrane

Other forms of this molecule

M [endocytic vesicle membrane]

N-glycan M [endocytic vesicle membrane]

nascent M [endoplasmic reticulum lumen]

N-glycan M [endoplasmic reticulum-Golgi intermediate compartment membrane]

M [endoplasmic reticulum-Golgi intermediate compartment membrane]

M [virion membrane]

N-glycan M [virion membrane]

Inferred To

N-glycan M [endoplasmic reticulum membrane] (Severe acute respiratory syndrome coronavirus 2)

Modified Residues

Name

N-glycosylated residue at 4

Coordinate

PsiMod Name

N-glycosylated residue

PsiMod Definition

A protein modification that effectively replaces a residue hydrogen atom on a nitrogen with a carbohydrate-like group through a glycosidic bond.

Disease

Name	Identifier	Synonyms
severe acute respiratory syndrome	2945	SARS-CoV infection, SARS

Cross References

PDB

3I6G

Interactors (6)

Accession	#Entities	Entities	Confidence Score	Evidence (IntAct)
UniProt:P59595 N	11	SUMO1-K62-ADPr-p-S177-Ncap [endoplasmic reticulum-Golgi intermediate compartment membrane] (R-COV-9683641) SUMO1-K62-ADPr-p-S177-Ncap [viral capsid] (R-COV-9685478) SUMO1-K62-ADPr-p-S177-Ncap [cytosol] (R-COV-9682916) ADPr-p-S177-Ncap [cytosol] (R-COV-9686058) p-S177-Ncap [cytosol] (R-COV-9683754) Ncap [cytosol] (R-COV-9683625) Ncap [plasma membrane] (R-COV-9683611) SUMO1-K62-ADPr-p-S177-Ncap [nucleolus] (R-COV-9683730) SUMO1-K62-ADPr-p-S177-Ncap [plasma membrane] (R-COV-9686063) N [cytosol] (R-COV-9681657) p-S177,S181,S185,S187,S189,S191,S195,T199,S203,S207-N [cytosol] (R-COV-9681626)	0.907	19
UniProt:P59637 E	9	nascent E [endoplasmic reticulum lumen] (R-COV-9683684) N-glycan E [endoplasmic reticulum lumen] (R-COV-9683652) 3xPalmC-E [endoplasmic reticulum lumen] (R-COV-9683597) Ub-3xPalmC-E [endoplasmic reticulum lumen] (R-COV-9683626) Ub-3xPalmC-E [endoplasmic reticulum membrane] (R-COV-9683767) Ub-3xPalmC-E [endocytic vesicle membrane] (R-COV-9698722) Ub-3xPalmC-E [Golgi membrane] (R-COV-9683694) Ub-3xPalmC-E [endoplasmic reticulum-Golgi intermediate compartment membrane] (R-COV-9698721) Ub-3xPalmC-E [virion membrane] (R-COV-9698716)	0.71	6
UniProt:Q9UHD2 TBK1	5	p-S172-TBK1 [cytosol] (R-HSA-168379) pS-172,K48polyUb-TBK1 [cytosol] (R-HSA-3249397) p-S172-TBK1 [cytosol] (R-HSA-450290) p-TBK1 [cytosol] (R-HSA-9008705) TBK1 [cytosol] (R-HSA-166267)	0.589	4
UniProt:O95786 DDX58	5	PolyUb-DDX58 [cytosol] (R-HSA-6782770) PolyUb-DDX58 [cytosol] (R-HSA-6782999) K48polyUb-DDX58 [cytosol] (R-HSA-3080568) DDX58 [cytosol] (R-HSA-168917) K63polyUb-DDX58 [cytosol] (R-HSA-918191)	0.589	4
UniProt:P61769 B2M	11	B2M(21-119) [specific granule lumen] (R-HSA-6806144) B2M(21-119) [early endosome membrane] (R-HSA-182298) B2M(21-119) [extracellular region] (R-HSA-1302721) B2M(21-119) [tertiary granule lumen] (R-HSA-6800179) B2M(21-119) [phagocytic vesicle membrane] (R-HSA-1236891) B2M(21-119) [recycling endosome membrane] (R-HSA-8863880) B2M(21-119) [early endosome lumen] (R-HSA-1236827) B2M(21-119) [ER to Golgi transport vesicle membrane] (R-HSA-983378) B2M(21-119) [Golgi membrane] (R-HSA-983403) B2M(21-119) [endoplasmic reticulum lumen] (R-HSA-983063) B2M(21-119) [plasma membrane] (R-HSA-167743)	0.524	2
UniProt:P59594 S	12	complex N-glycan-PALM-Spike S1 Fragment [endocytic vesicle membrane] (R-COV-9686693) complex N-glycan-PALM-Spike S2 Fragment [endocytic vesicle membrane] (R-COV-9686730) complex N-glycan-PALM-Spike S1 Fragment [virion membrane] (R-COV-9686706) complex N-glycan-PALM-Spike S2 Fragment [virion membrane] (R-COV-9686724) nascent Spike [endoplasmic reticulum lumen] (R-COV-9682868) N-glycan Spike [endoplasmic reticulum lumen] (R-COV-9683594) trimmed unfolded N-glycan Spike [endoplasmic reticulum lumen] (R-COV-9683716) trimmed N-glycan Spike [endoplasmic reticulum lumen] (R-COV-9683608) trimmed N-glycan-PALM-Spike [endoplasmic reticulum lumen] (R-COV-9683638) trimmed N-glycan-PALM-Spike [endoplasmic reticulum-Golgi intermediate compartment] (R-COV-9683657) complex N-glycan-PALM-Spike [endoplasmic reticulum-Golgi intermediate compartment] (R-COV-9683617) complex N-glycan-PALM-Spike [virion membrane] (R-COV-9685469)	0.463	2

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