phospho-SUMO1-K62-ADPr-p-S177-Ncap [cytosol]

Stable Identifier
R-COV-9694558
Type
Protein [EntityWithAccessionedSequence]
Species
Severe acute respiratory syndrome coronavirus 2
Compartment
cytosol
Synonyms
P0DTC9
Locations in the PathwayBrowser for interactor UniProt:P0DTC9
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General

SARS-CoV-2 mRNA2 has a length of 3,822 nt and encodes the 1,273 aa spike preprotein (Wu et al, 2020).

Literature References
PubMed ID Title Journal Year
15848177 Sumoylation of the nucleocapsid protein of severe acute respiratory syndrome coronavirus

Li, FQ, Xiao, H, Tam, JP, Liu, DX

FEBS Lett. 2005
External Reference Information
External Reference
UniProt:P0DTC9 N
Gene Names
N
Chain
chain:1-419
Reference Genes
BioGPS Gene:43740575 N
KEGG Gene (Hepatitis C Virus):43740575 N
Monarch:43740575 N
NCBI Gene:43740575 N
Reference Transcript
Participates
as an output of
as an input of
as a component of
Other forms of this molecule
phospho-p-S177,S181,S185,S187,S189,S191,S195,T199,S203,S207-N [cytosol]
phospho-SUMO1-K62-ADPr-p-S177-Ncap [endoplasmic reticulum-Golgi intermediate compartment membrane]
phospho-ADPr-p-S177-Ncap [cytosol]
phospho-p-S177-Ncap [cytosol]
Ncap [cytosol]
Ncap [plasma membrane]
phospho-SUMO1-K62-ADPr-p-S177-Ncap [nucleolus]
phospho-SUMO1-K62-ADPr-p-S177-Ncap [plasma membrane]
N [cytosol]
Inferred From
SUMO1-K62-ADPr-p-S177-Ncap [cytosol] (Human SARS coronavirus)
Modified Residues
Name
O-phospho-L-serine at 176
Coordinate
176
PsiMod Name
O-phospho-L-serine [MOD:00046]
PsiMod Definition
A protein modification that effectively converts an L-serine residue to O-phospho-L-serine.
Name
sumoylated lysine at 61
Coordinate
61
PsiMod Name
sumoylated lysine
PsiMod Definition
A protein modification that effectively crosslinks the N6-amino of a peptidyl lysine with the carboxyl-terminal glycine of a sumo (Small Ubiquitin-related MOdifier) protein.
Name
acetylated L-serine at 2
Coordinate
2
PsiMod Name
acetylated L-serine
PsiMod Definition
A protein modification that effectively converts an L-serine residue to either N-acetyl-L-serine, O-acetyl-L-serine, or N,O-diacetyl-L-serine.
Name
adenosine diphosphoribosyl (ADP-ribosyl) modified residue at unknown position
PsiMod Name
adenosine diphosphoribosyl (ADP-ribosyl) modified residue
PsiMod Definition
A protein modification that effectively results from forming an adduct with ADP-ribose through formation of a glycosidic bond.
Disease
Name Identifier Synonyms
COVID-19 DOID:0080600 2019 Novel Coronavirus (2019-nCoV), Wuhan seafood market pneumonia virus infection, 2019-nCoV infection, Wuhan coronavirus infection
Cross References
RefSeq
PDB
Interactors (21)
Accession #Entities Entities Confidence Score Evidence (IntAct)
 UniProt:P0DTC9 N  10 0.823 11
 UniProt:Q13283 G3BP1      0.725 5
 UniProt:Q9UN86 G3BP2      0.725 5
 ChEBI:73279 POLY(URIDYLIC ACID)      0.642 4
 UniProt:Q96SB4 SRPK1      0.623 2
 UniProt:P61289 PSME3  2 0.544 3
 UniProt:Q6PKG0 LARP1      0.527 2
 UniProt:Q8TAD8 SNIP1      0.527 2
 UniProt:Q9HCE1 MOV10  1 0.527 2
 UniProt:P67870 CSNK2B  5 0.527 2
 UniProt:O43818 RRP9  1 0.527 2
 UniProt:Q9Y3U8 RPL36  1 0.527 2
 UniProt:P19784 CSNK2A2  2 0.527 2
 UniProt:Q13310 PABP4      0.527 2
 UniProt:Q92900 UPF1  2 0.527 2
 UniProt:Q8NCA5 FA98A      0.527 2
 UniProt:Q9NW13 RBM28  1 0.527 2
 UniProt:Q6NZI2 CAVIN1  2 0.527 2
 UniProt:Q9NR30 DDX21  1 0.527 2
 UniProt:P11940 PABPC1  1 0.527 2
 IntAct:EBI-26430259 AUUAAAG      0.522 2
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