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O-glycosyl 3a tetramer [endoplasmic reticulum-Golgi intermediate compartment membrane]
Stable Identifier
R-COV-9694598
Type
Complex
Species
Severe acute respiratory syndrome coronavirus 2
Compartment
endoplasmic reticulum-Golgi intermediate compartment membrane
Locations in the PathwayBrowser
Expand all
Disease (Homo sapiens)
Infectious disease (Homo sapiens)
Viral Infection Pathways (Homo sapiens)
SARS-CoV Infections (Homo sapiens)
SARS-CoV-2 Infection (Homo sapiens)
Late SARS-CoV-2 Infection Events (Homo sapiens)
Translation of Structural Proteins (Homo sapiens)
Maturation of protein 3a (Homo sapiens)
3a localizes to the cell membrane (Homo sapiens)
O-glycosyl 3a tetramer [endoplasmic reticulum-Golgi intermediate compartment membrane] (Severe acute respiratory syndrome coronavirus 2)
Protein 3a forms a homotetramer (Homo sapiens)
O-glycosyl 3a tetramer [endoplasmic reticulum-Golgi intermediate compartment membrane] (Severe acute respiratory syndrome coronavirus 2)
Virion Assembly and Release (Homo sapiens)
Accessory proteins are recruited to the maturing virion (Homo sapiens)
O-glycosyl 3a tetramer [endoplasmic reticulum-Golgi intermediate compartment membrane] (Severe acute respiratory syndrome coronavirus 2)
S3:M:E:encapsidated SARS-CoV-2 genomic RNA:7a:O-glycosyl 3a tetramer [endoplasmic reticulum-Golgi intermediate compartment membrane] (Severe acute respiratory syndrome coronavirus 2)
7a:O-glycosyl 3a tetramer [endoplasmic reticulum-Golgi intermediate compartment membrane] (Severe acute respiratory syndrome coronavirus 2)
O-glycosyl 3a tetramer [endoplasmic reticulum-Golgi intermediate compartment membrane] (Severe acute respiratory syndrome coronavirus 2)
SARS virus buds into ERGIC lumen (Homo sapiens)
S3:M:E:encapsidated SARS-CoV-2 genomic RNA:7a:O-glycosyl 3a tetramer [endoplasmic reticulum-Golgi intermediate compartment membrane] (Severe acute respiratory syndrome coronavirus 2)
7a:O-glycosyl 3a tetramer [endoplasmic reticulum-Golgi intermediate compartment membrane] (Severe acute respiratory syndrome coronavirus 2)
O-glycosyl 3a tetramer [endoplasmic reticulum-Golgi intermediate compartment membrane] (Severe acute respiratory syndrome coronavirus 2)
SARS-CoV-2-host interactions (Homo sapiens)
SARS-CoV-2 activates/modulates innate and adaptive immune responses (Homo sapiens)
SARS-CoV-2 3a binds to STING (Homo sapiens)
STING:O-glycosyl 3a tetramer [endoplasmic reticulum-Golgi intermediate compartment membrane] (Homo sapiens)
O-glycosyl 3a tetramer [endoplasmic reticulum-Golgi intermediate compartment membrane] (Severe acute respiratory syndrome coronavirus 2)
O-glycosyl 3a tetramer [endoplasmic reticulum-Golgi intermediate compartment membrane] (Severe acute respiratory syndrome coronavirus 2)
SARS-CoV-2 modulates autophagy (Homo sapiens)
SARS-CoV-2 3a binds to UVRAG (Homo sapiens)
UVRAG:O-glycosyl 3a tetramer [endoplasmic reticulum-Golgi intermediate compartment membrane] (Homo sapiens)
O-glycosyl 3a tetramer [endoplasmic reticulum-Golgi intermediate compartment membrane] (Severe acute respiratory syndrome coronavirus 2)
O-glycosyl 3a tetramer [endoplasmic reticulum-Golgi intermediate compartment membrane] (Severe acute respiratory syndrome coronavirus 2)
SARS-CoV-2 targets host intracellular signalling and regulatory pathways (Homo sapiens)
SARS-CoV-2 3a tetramer binds to CAV1 (Homo sapiens)
CAV1:3a [endoplasmic reticulum-Golgi intermediate compartment membrane] (Homo sapiens)
O-glycosyl 3a tetramer [endoplasmic reticulum-Golgi intermediate compartment membrane] (Severe acute respiratory syndrome coronavirus 2)
O-glycosyl 3a tetramer [endoplasmic reticulum-Golgi intermediate compartment membrane] (Severe acute respiratory syndrome coronavirus 2)
General
This COVID-19 Complex instance was generated via electronic inference from a curated CoV-1 (Human SARS coronavirus) Reactome instance. In Reactome, inference is the process used to automatically create orthologous Pathways, Reactions and PhysicalEntities from our expertly curated data (https://reactome.org/documentation/inferred-events).
Participants
components
x 4
O-glycosyl 3a [endoplasmic reticulum-Golgi intermediate compartment membrane]
(Severe acute respiratory syndrome coronavirus 2)
Participates
as a component of
CAV1:3a [endoplasmic reticulum-Golgi intermediate compartment membrane] (Homo sapiens)
UVRAG:O-glycosyl 3a tetramer [endoplasmic reticulum-Golgi intermediate compartment membrane] (Homo sapiens)
STING:O-glycosyl 3a tetramer [endoplasmic reticulum-Golgi intermediate compartment membrane] (Homo sapiens)
7a:O-glycosyl 3a tetramer [endoplasmic reticulum-Golgi intermediate compartment membrane] (Severe acute respiratory syndrome coronavirus 2)
as an input of
SARS-CoV-2 3a tetramer binds to CAV1 (Homo sapiens)
SARS-CoV-2 3a binds to UVRAG (Homo sapiens)
SARS-CoV-2 3a binds to STING (Homo sapiens)
3a localizes to the cell membrane (Homo sapiens)
Accessory proteins are recruited to the maturing virion (Homo sapiens)
as an output of
Protein 3a forms a homotetramer (Homo sapiens)
Inferred From
O-glycosyl 3a tetramer [endoplasmic reticulum-Golgi intermediate compartment membrane]
(Human SARS coronavirus)
Disease
Name
Identifier
Synonyms
COVID-19
DOID:0080600
2019 Novel Coronavirus (2019-nCoV), Wuhan seafood market pneumonia virus infection, 2019-nCoV infection, Wuhan coronavirus infection
Cross References
ComplexPortal
CPX-6098
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