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phospho-erkA [cytosol]
Stable Identifier
R-DDI-109853
Type
Protein [EntityWithAccessionedSequence]
Species
Dictyostelium discoideum
Compartment
cytosol
Synonyms
p-T185,Y187-MAPK1, P42525
Locations in the PathwayBrowser
Expand all
Cellular responses to external stimuli (Dictyostelium discoideum)
Cellular responses to stress (Dictyostelium discoideum)
Cellular response to heat stress (Dictyostelium discoideum)
Regulation of HSF1-mediated heat shock response (Dictyostelium discoideum)
Constitutive phosphorylation by pERK1/2 (Dictyostelium discoideum)
p-T,Y MAPK dimers [cytosol] (Dictyostelium discoideum)
p-T185,Y187 MAPK1 dimer [cytosol] (Dictyostelium discoideum)
phospho-erkA [cytosol] (Dictyostelium discoideum)
Developmental Biology (Dictyostelium discoideum)
Nervous system development (Dictyostelium discoideum)
Axon guidance (Dictyostelium discoideum)
L1CAM interactions (Dictyostelium discoideum)
Recycling pathway of L1 (Dictyostelium discoideum)
Phosphorylation of L1 by ERK (Dictyostelium discoideum)
pL1 (S1204, 1248):ERK2:clathrin-dynamin complex [endosome] (Dictyostelium discoideum)
phospho-erkA [cytosol] (Dictyostelium discoideum)
phospho-erkA [cytosol] (Dictyostelium discoideum)
Immune System (Dictyostelium discoideum)
Innate Immune System (Dictyostelium discoideum)
Fcgamma receptor (FCGR) dependent phagocytosis (Dictyostelium discoideum)
Regulation of actin dynamics for phagocytic cup formation (Dictyostelium discoideum)
p-ERK phosphorylates WAVEs and ABI (Dictyostelium discoideum)
p-T,Y MAPK dimers [cytosol] (Dictyostelium discoideum)
p-T185,Y187 MAPK1 dimer [cytosol] (Dictyostelium discoideum)
phospho-erkA [cytosol] (Dictyostelium discoideum)
Signal Transduction (Dictyostelium discoideum)
MAPK family signaling cascades (Dictyostelium discoideum)
MAPK1/MAPK3 signaling (Dictyostelium discoideum)
RAF-independent MAPK1/3 activation (Dictyostelium discoideum)
Cytosolic DUSPs dephosphorylate MAPKs (Dictyostelium discoideum)
p-T,Y MAPK monomers and dimers [cytosol] (Dictyostelium discoideum)
p-T,Y MAPK dimers [cytosol] (Dictyostelium discoideum)
p-T185,Y187 MAPK1 dimer [cytosol] (Dictyostelium discoideum)
phospho-erkA [cytosol] (Dictyostelium discoideum)
p-T,Y MAPKs [cytosol] (Dictyostelium discoideum)
phospho-erkA [cytosol] (Dictyostelium discoideum)
Phosphorylated MAPKs translocate into the nucleus (Dictyostelium discoideum)
p-T,Y MAPK monomers and dimers [cytosol] (Dictyostelium discoideum)
p-T,Y MAPK dimers [cytosol] (Dictyostelium discoideum)
p-T185,Y187 MAPK1 dimer [cytosol] (Dictyostelium discoideum)
phospho-erkA [cytosol] (Dictyostelium discoideum)
p-T,Y MAPKs [cytosol] (Dictyostelium discoideum)
phospho-erkA [cytosol] (Dictyostelium discoideum)
p-T,Y MAPKs dimerize (Dictyostelium discoideum)
p-T,Y MAPK dimers [cytosol] (Dictyostelium discoideum)
p-T185,Y187 MAPK1 dimer [cytosol] (Dictyostelium discoideum)
phospho-erkA [cytosol] (Dictyostelium discoideum)
p-T,Y MAPKs [cytosol] (Dictyostelium discoideum)
phospho-erkA [cytosol] (Dictyostelium discoideum)
RAF/MAP kinase cascade (Dictyostelium discoideum)
Negative regulation of MAPK pathway (Dictyostelium discoideum)
Cytosolic DUSPs dephosphorylate MAPKs (Dictyostelium discoideum)
p-T,Y MAPK monomers and dimers [cytosol] (Dictyostelium discoideum)
p-T,Y MAPK dimers [cytosol] (Dictyostelium discoideum)
p-T185,Y187 MAPK1 dimer [cytosol] (Dictyostelium discoideum)
phospho-erkA [cytosol] (Dictyostelium discoideum)
p-T,Y MAPKs [cytosol] (Dictyostelium discoideum)
phospho-erkA [cytosol] (Dictyostelium discoideum)
Negative feedback regulation of MAPK pathway (Dictyostelium discoideum)
Activated MAPK phosphorylates RAF1 (Dictyostelium discoideum)
p-T,Y MAPK monomers and dimers [cytosol] (Dictyostelium discoideum)
p-T,Y MAPK dimers [cytosol] (Dictyostelium discoideum)
p-T185,Y187 MAPK1 dimer [cytosol] (Dictyostelium discoideum)
phospho-erkA [cytosol] (Dictyostelium discoideum)
p-T,Y MAPKs [cytosol] (Dictyostelium discoideum)
phospho-erkA [cytosol] (Dictyostelium discoideum)
Activated MAPKs phosphorylate BRAF (Dictyostelium discoideum)
p-T,Y MAPK monomers and dimers [cytosol] (Dictyostelium discoideum)
p-T,Y MAPK dimers [cytosol] (Dictyostelium discoideum)
p-T185,Y187 MAPK1 dimer [cytosol] (Dictyostelium discoideum)
phospho-erkA [cytosol] (Dictyostelium discoideum)
p-T,Y MAPKs [cytosol] (Dictyostelium discoideum)
phospho-erkA [cytosol] (Dictyostelium discoideum)
PTPN7 binds p-T,Y-MAPK (Dictyostelium discoideum)
PTPN7:p-T,Y-MAPK dimers [cytosol] (Dictyostelium discoideum)
p-T,Y MAPK dimers [cytosol] (Dictyostelium discoideum)
p-T185,Y187 MAPK1 dimer [cytosol] (Dictyostelium discoideum)
phospho-erkA [cytosol] (Dictyostelium discoideum)
p-T,Y MAPK dimers [cytosol] (Dictyostelium discoideum)
p-T185,Y187 MAPK1 dimer [cytosol] (Dictyostelium discoideum)
phospho-erkA [cytosol] (Dictyostelium discoideum)
PTPN7 dephosphorylates p-T,Y-MAPKs (Dictyostelium discoideum)
PTPN7:p-T,Y-MAPK dimers [cytosol] (Dictyostelium discoideum)
p-T,Y MAPK dimers [cytosol] (Dictyostelium discoideum)
p-T185,Y187 MAPK1 dimer [cytosol] (Dictyostelium discoideum)
phospho-erkA [cytosol] (Dictyostelium discoideum)
Phosphorylated MAPKs translocate into the nucleus (Dictyostelium discoideum)
p-T,Y MAPK monomers and dimers [cytosol] (Dictyostelium discoideum)
p-T,Y MAPK dimers [cytosol] (Dictyostelium discoideum)
p-T185,Y187 MAPK1 dimer [cytosol] (Dictyostelium discoideum)
phospho-erkA [cytosol] (Dictyostelium discoideum)
p-T,Y MAPKs [cytosol] (Dictyostelium discoideum)
phospho-erkA [cytosol] (Dictyostelium discoideum)
p-T,Y MAPKs dimerize (Dictyostelium discoideum)
p-T,Y MAPK dimers [cytosol] (Dictyostelium discoideum)
p-T185,Y187 MAPK1 dimer [cytosol] (Dictyostelium discoideum)
phospho-erkA [cytosol] (Dictyostelium discoideum)
p-T,Y MAPKs [cytosol] (Dictyostelium discoideum)
phospho-erkA [cytosol] (Dictyostelium discoideum)
Signaling by GPCR (Dictyostelium discoideum)
GPCR downstream signalling (Dictyostelium discoideum)
G alpha (i) signalling events (Dictyostelium discoideum)
Opioid Signalling (Dictyostelium discoideum)
G-protein mediated events (Dictyostelium discoideum)
PLC beta mediated events (Dictyostelium discoideum)
Ca-dependent events (Dictyostelium discoideum)
phospho-PLA2 pathway (Dictyostelium discoideum)
Phosphorylation of cPLA2 by ERK-2 (Dictyostelium discoideum)
phospho-erkA [cytosol] (Dictyostelium discoideum)
Signaling by Nuclear Receptors (Dictyostelium discoideum)
ESR-mediated signaling (Dictyostelium discoideum)
Extra-nuclear estrogen signaling (Dictyostelium discoideum)
Estrogen-stimulated signaling through PRKCZ (Dictyostelium discoideum)
ESR1- and PRCKZ-dependent MAPK1 translocation to the nucleus (Dictyostelium discoideum)
p-T185,Y187 MAPK1 dimer [cytosol] (Dictyostelium discoideum)
phospho-erkA [cytosol] (Dictyostelium discoideum)
Signaling by Receptor Tyrosine Kinases (Dictyostelium discoideum)
Signaling by NTRKs (Dictyostelium discoideum)
Signaling by NTRK1 (TRKA) (Dictyostelium discoideum)
Signalling to ERKs (Dictyostelium discoideum)
Prolonged ERK activation events (Dictyostelium discoideum)
Frs2-mediated activation (Dictyostelium discoideum)
p-T,Y MAPK dimers translocate to nucleus (Dictyostelium discoideum)
p-T,Y MAPK dimers [cytosol] (Dictyostelium discoideum)
p-T185,Y187 MAPK1 dimer [cytosol] (Dictyostelium discoideum)
phospho-erkA [cytosol] (Dictyostelium discoideum)
p-T,Y MAPKs dimerize (Dictyostelium discoideum)
p-T,Y MAPK dimers [cytosol] (Dictyostelium discoideum)
p-T185,Y187 MAPK1 dimer [cytosol] (Dictyostelium discoideum)
phospho-erkA [cytosol] (Dictyostelium discoideum)
p-T,Y MAPKs [cytosol] (Dictyostelium discoideum)
phospho-erkA [cytosol] (Dictyostelium discoideum)
Signaling by Rho GTPases (Dictyostelium discoideum)
RHO GTPase Effectors (Dictyostelium discoideum)
RHO GTPases Activate WASPs and WAVEs (Dictyostelium discoideum)
p-ERK phosphorylates WAVEs and ABI (Dictyostelium discoideum)
p-T,Y MAPK dimers [cytosol] (Dictyostelium discoideum)
p-T185,Y187 MAPK1 dimer [cytosol] (Dictyostelium discoideum)
phospho-erkA [cytosol] (Dictyostelium discoideum)
External Reference Information
External Reference
UniProt:P42525
Gene Names
erkA
Reference Genes
dictyBase:DDB_G0286353
ENSEMBL:DDB_G0286353
KEGG Gene (Dictyostelium discoideum):DDB_G0286353 erkA
Participant Of
input
Phosphorylation of L1 by ERK
hasComponent
p-T185,Y187 MAPK1 dimer [cytosol]
pL1 (S1204, 1248):ERK2:clathrin-dynamin complex [endosome]
hasMember
p-T,Y MAPKs [cytosol]
Other forms of this molecule
erkA [cytosol]
erkA [nucleoplasm]
erkA [cytosol]
erkA [cytosol]
phospho-erkA [cytosol]
phospho-erkA [cytosol]
phospho-erkA [nucleoplasm]
phospho-erkA [nucleoplasm]
erkA [nucleoplasm]
phospho-erkA [nucleoplasm]
erkA [nucleoplasm]
erkA [azurophil granule lumen]
erkA [ficolin-1-rich granule lumen]
erkA [extracellular region]
erkA [secretory granule lumen]
phospho-erkA [cytosol]
erkA [cytosol]
erkA [cytosol]
erkA [nucleoplasm]
phospho-erkA [cytosol]
erkA [cytosol]
phospho-erkA [cytosol]
phospho-erkA [cytosol]
phospho-erkA [nucleoplasm]
phospho-erkA [nucleoplasm]
phospho-erkA [nucleoplasm]
phospho-erkA [nucleoplasm]
phospho-erkA [nucleoplasm]
phospho-erkA [nucleoplasm]
phospho-erkA [nucleoplasm]
erkA [cytosol]
phospho-erkA [cytosol]
erkA [cytosol]
phospho-erkA [cytosol]
erkA [nucleoplasm]
erkA [nucleoplasm]
erkA [nucleoplasm]
phospho-erkA [cytosol]
phospho-erkA [cytosol]
phospho-erkA [cytosol]
erkA [cytosol]
erkA [cytosol]
erkA [cytosol]
phospho-erkA [nucleoplasm]
phospho-erkA [cytosol]
erkA [cytosol]
phospho-erkA [cytosol]
phospho-erkA [nucleoplasm]
phospho-erkA [cytosol]
Inferred From
p-T185,Y187-MAPK1 [cytosol] (Homo sapiens)
Modified Residues
Name
O-phospho-L-threonine at 185 (in Homo sapiens)
Coordinate
185
PsiMod Name
O-phospho-L-threonine [MOD:00047]
PsiMod Definition
A protein modification that effectively converts an L-threonine residue to O-phospho-L-threonine.
Name
O4'-phospho-L-tyrosine at 187 (in Homo sapiens)
Coordinate
187
PsiMod Name
O4'-phospho-L-tyrosine [MOD:00048]
PsiMod Definition
A protein modification that effectively converts an L-tyrosine residue to O4'-phospho-L-tyrosine.
Cross References
PRO
P42525
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