Reactome | adprt2 [nucleoplasm]

adprt2 [nucleoplasm]

Stable Identifier

R-DDI-201568-5

Type

Protein [EntityWithAccessionedSequence]

Species

Dictyostelium discoideum

Compartment

nucleoplasm

Synonyms

PARP1, Q8I7C6

Locations in the PathwayBrowser

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DNA Repair (Dictyostelium discoideum)

- Base Excision Repair (Dictyostelium discoideum)
  - Resolution of Abasic Sites (AP sites) (Dictyostelium discoideum)
    - Resolution of AP sites via the multiple-nucleotide patch replacement pathway (Dictyostelium discoideum)
      - POLB-Dependent Long Patch Base Excision Repair (Dictyostelium discoideum)
        
        PARG dePARylates PARP1,PARP2 (Dictyostelium discoideum)
        
        PARP1,PARP2 dimers [nucleoplasm] (Dictyostelium discoideum)
        
        PARP1,PARP2 [nucleoplasm] (Dictyostelium discoideum)
        
        Homologues of PARP1 [nucleoplasm] (Dictyostelium discoideum)
        
        adprt2 [nucleoplasm] (Dictyostelium discoideum)
        
        PARP1,PARP2 dimers and FEN1 bind POLB and displace APEX1 from damaged AP site (Dictyostelium discoideum)
        
        PARP1,PARP2 dimers [nucleoplasm] (Dictyostelium discoideum)
        
        PARP1,PARP2 [nucleoplasm] (Dictyostelium discoideum)
        
        Homologues of PARP1 [nucleoplasm] (Dictyostelium discoideum)
        
        adprt2 [nucleoplasm] (Dictyostelium discoideum)
        
        PARP1,PARP2:FEN1:POLB:SSB(3'dNMP-displaced 5'ddRP)-dsDNA [nucleoplasm] (Dictyostelium discoideum)
        
        PARP1,PARP2 dimers [nucleoplasm] (Dictyostelium discoideum)
        
        PARP1,PARP2 [nucleoplasm] (Dictyostelium discoideum)
        
        Homologues of PARP1 [nucleoplasm] (Dictyostelium discoideum)
        
        adprt2 [nucleoplasm] (Dictyostelium discoideum)
        
        PARP1,PARP2 dimers bound to FEN1 and POLB autoPARylate (Dictyostelium discoideum)
        
        PARP1,PARP2 dimers [nucleoplasm] (Dictyostelium discoideum)
        
        PARP1,PARP2 [nucleoplasm] (Dictyostelium discoideum)
        
        Homologues of PARP1 [nucleoplasm] (Dictyostelium discoideum)
        
        adprt2 [nucleoplasm] (Dictyostelium discoideum)
        
        PARP1,PARP2:FEN1:POLB:SSB(3'poly-dNMP-displaced 5'ddRP-FLAP)-dsDNA [nucleoplasm] (Dictyostelium discoideum)
        
        PARP1,PARP2 dimers [nucleoplasm] (Dictyostelium discoideum)
        
        PARP1,PARP2 [nucleoplasm] (Dictyostelium discoideum)
        
        Homologues of PARP1 [nucleoplasm] (Dictyostelium discoideum)
        
        adprt2 [nucleoplasm] (Dictyostelium discoideum)
        
        POLB-mediated DNA strand displacement synthesis (Dictyostelium discoideum)
        
        PARP1,PARP2:FEN1:POLB:SSB(3'dNMP-displaced 5'ddRP)-dsDNA [nucleoplasm] (Dictyostelium discoideum)
        
        PARP1,PARP2 dimers [nucleoplasm] (Dictyostelium discoideum)
        
        PARP1,PARP2 [nucleoplasm] (Dictyostelium discoideum)
        
        Homologues of PARP1 [nucleoplasm] (Dictyostelium discoideum)
        
        adprt2 [nucleoplasm] (Dictyostelium discoideum)
        
        PARP1,PARP2:FEN1:POLB:SSB(3'poly-dNMP-displaced 5'ddRP-FLAP)-dsDNA [nucleoplasm] (Dictyostelium discoideum)
        
        PARP1,PARP2 dimers [nucleoplasm] (Dictyostelium discoideum)
        
        PARP1,PARP2 [nucleoplasm] (Dictyostelium discoideum)
        
        Homologues of PARP1 [nucleoplasm] (Dictyostelium discoideum)
        
        adprt2 [nucleoplasm] (Dictyostelium discoideum)
- Nucleotide Excision Repair (Dictyostelium discoideum)
  - Global Genome Nucleotide Excision Repair (GG-NER) (Dictyostelium discoideum)
    - DNA Damage Recognition in GG-NER (Dictyostelium discoideum)
      - PARP1 or PARP2 PARylates DDB2 and autoPARylates (Dictyostelium discoideum)
        
        Ub:XPC:RAD23:CETN2:Distorted dsDNA:UV-DDB:PARP1,PARP2 [nucleoplasm] (Dictyostelium discoideum)
        
        PARP1,PARP2 dimers [nucleoplasm] (Dictyostelium discoideum)
        
        PARP1,PARP2 [nucleoplasm] (Dictyostelium discoideum)
        
        Homologues of PARP1 [nucleoplasm] (Dictyostelium discoideum)
        
        adprt2 [nucleoplasm] (Dictyostelium discoideum)
      - PARP1 or PARP2 binds DDB2 at GG-NER site (Dictyostelium discoideum)
        
        PARP1,PARP2 dimers [nucleoplasm] (Dictyostelium discoideum)
        
        PARP1,PARP2 [nucleoplasm] (Dictyostelium discoideum)
        
        Homologues of PARP1 [nucleoplasm] (Dictyostelium discoideum)
        
        adprt2 [nucleoplasm] (Dictyostelium discoideum)
        
        Ub:XPC:RAD23:CETN2:Distorted dsDNA:UV-DDB:PARP1,PARP2 [nucleoplasm] (Dictyostelium discoideum)
        
        PARP1,PARP2 dimers [nucleoplasm] (Dictyostelium discoideum)
        
        PARP1,PARP2 [nucleoplasm] (Dictyostelium discoideum)
        
        Homologues of PARP1 [nucleoplasm] (Dictyostelium discoideum)
        
        adprt2 [nucleoplasm] (Dictyostelium discoideum)

External Reference Information

External Reference

UniProt:Q8I7C6

Gene Names

adprt2

Reference Genes

BioGPS Gene:8628891 adprt2

dictyBase:DDB_G0292820

ENSEMBL:DDB_G0292820

KEGG Gene (Dictyostelium discoideum):DDB_G0292820 adprt2

Monarch:8628891 adprt2

NCBI Gene:8628891 adprt2

Reference Transcript

RefSeq:XM_629371.1 adprt2

Participates

as a member of

Homologues of PARP1 [nucleoplasm] (Dictyostelium discoideum)

Other forms of this molecule

adprt2 [nucleoplasm]

Inferred From

PARP1 [nucleoplasm] (Homo sapiens)

Cross References

RefSeq

XP_629373.1