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sybA [plasma membrane]
Stable Identifier
R-DDI-210516
Type
Protein [EntityWithAccessionedSequence]
Species
Dictyostelium discoideum
Compartment
plasma membrane
Synonyms
VAMP2, Q6TMJ9
Locations in the PathwayBrowser
Expand all
Immune System (Dictyostelium discoideum)
Cytokine Signaling in Immune system (Dictyostelium discoideum)
Signaling by Interleukins (Dictyostelium discoideum)
Other interleukin signaling (Dictyostelium discoideum)
TXLNA (IL14) binds syntaxin1A (Dictyostelium discoideum)
STXA1:SNAP25,STXBP2, VAMP2 [plasma membrane] (Dictyostelium discoideum)
SNAP25,STXBP2, VAMP2 [plasma membrane] (Dictyostelium discoideum)
sybA [plasma membrane] (Dictyostelium discoideum)
Vesicle-mediated transport (Dictyostelium discoideum)
Membrane Trafficking (Dictyostelium discoideum)
Clathrin-mediated endocytosis (Dictyostelium discoideum)
BAR domain proteins recruit dynamin (Dictyostelium discoideum)
PI(4,5)P2:p-T156 AP-2:clathrin:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo:F-BAR proteins:BAR domain proteins:ARP2/3 complex:WASL:f-actin:HIP dimers [plasma membrane] (Dictyostelium discoideum)
PI(4,5)P2:p-T156 AP-2:clathrin:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo:F-BAR proteins:BAR domain proteins [plasma membrane] (Dictyostelium discoideum)
PI(4,5)P2:ITSNs:EPS15:REPS1:clathrin:NECAPs:p-T156 AP-2:SGIP1:CLASP proteins:cargo [plasma membrane] (Dictyostelium discoideum)
CLASP proteins:cargo [plasma membrane] (Dictyostelium discoideum)
PICALM:VAMP2,3,8 [plasma membrane] (Dictyostelium discoideum)
sybA [plasma membrane] (Dictyostelium discoideum)
PI(4,5)P2:p-T156 AP-2:clathrin:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo:F-BAR proteins:BAR domain proteins:ARP2/3 complex:WASL:f-actin:HIP dimers:DNM:GTP [plasma membrane] (Dictyostelium discoideum)
PI(4,5)P2:p-T156 AP-2:clathrin:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo:F-BAR proteins:BAR domain proteins:ARP2/3 complex:WASL:f-actin:HIP dimers [plasma membrane] (Dictyostelium discoideum)
PI(4,5)P2:p-T156 AP-2:clathrin:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo:F-BAR proteins:BAR domain proteins [plasma membrane] (Dictyostelium discoideum)
PI(4,5)P2:ITSNs:EPS15:REPS1:clathrin:NECAPs:p-T156 AP-2:SGIP1:CLASP proteins:cargo [plasma membrane] (Dictyostelium discoideum)
CLASP proteins:cargo [plasma membrane] (Dictyostelium discoideum)
PICALM:VAMP2,3,8 [plasma membrane] (Dictyostelium discoideum)
sybA [plasma membrane] (Dictyostelium discoideum)
CLASP proteins and cargo are recruited to the nascent clathrin-coated pit (Dictyostelium discoideum)
CLASP proteins:cargo [plasma membrane] (Dictyostelium discoideum)
PICALM:VAMP2,3,8 [plasma membrane] (Dictyostelium discoideum)
sybA [plasma membrane] (Dictyostelium discoideum)
PI(4,5)P2:p-T156 AP-2:clathrin:FCHO1,2:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo [plasma membrane] (Dictyostelium discoideum)
CLASP proteins:cargo [plasma membrane] (Dictyostelium discoideum)
PICALM:VAMP2,3,8 [plasma membrane] (Dictyostelium discoideum)
sybA [plasma membrane] (Dictyostelium discoideum)
Cargo recognition for clathrin-mediated endocytosis (Dictyostelium discoideum)
PICALM binds R-SNAREs (Dictyostelium discoideum)
PICALM:VAMP2,3,8 [plasma membrane] (Dictyostelium discoideum)
sybA [plasma membrane] (Dictyostelium discoideum)
sybA [plasma membrane] (Dictyostelium discoideum)
Clathrin recruits PIK3C2A (Dictyostelium discoideum)
PI(4,5)P2:p-T156 AP-2:clathrin:FCHO1,2:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo [plasma membrane] (Dictyostelium discoideum)
CLASP proteins:cargo [plasma membrane] (Dictyostelium discoideum)
PICALM:VAMP2,3,8 [plasma membrane] (Dictyostelium discoideum)
sybA [plasma membrane] (Dictyostelium discoideum)
PI(4,5)P2:p-T156 AP-2:clathrin:FCHO1,2:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo:PIK3C2A [plasma membrane] (Dictyostelium discoideum)
PI(4,5)P2:p-T156 AP-2:clathrin:FCHO1,2:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo [plasma membrane] (Dictyostelium discoideum)
CLASP proteins:cargo [plasma membrane] (Dictyostelium discoideum)
PICALM:VAMP2,3,8 [plasma membrane] (Dictyostelium discoideum)
sybA [plasma membrane] (Dictyostelium discoideum)
Clathrin-associated PIK3C2A phosphorylates PI(4)P to PI(3,4)P2 (Dictyostelium discoideum)
PI(4,5)P2:p-T156 AP-2:clathrin:FCHO1,2:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo:PIK3C2A [plasma membrane] (Dictyostelium discoideum)
PI(4,5)P2:p-T156 AP-2:clathrin:FCHO1,2:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo [plasma membrane] (Dictyostelium discoideum)
CLASP proteins:cargo [plasma membrane] (Dictyostelium discoideum)
PICALM:VAMP2,3,8 [plasma membrane] (Dictyostelium discoideum)
sybA [plasma membrane] (Dictyostelium discoideum)
Dynamin-mediated GTP hydrolysis promotes vesicle scission (Dictyostelium discoideum)
PI(4)P:p-T156 AP-2:clathrin:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo:F-BAR proteins:BAR domain proteins:ARP2/3 complex:WASL:f-actin:HIP dimers:DNM:GTP:SYNJs [plasma membrane] (Dictyostelium discoideum)
CLASP proteins:cargo [plasma membrane] (Dictyostelium discoideum)
PICALM:VAMP2,3,8 [plasma membrane] (Dictyostelium discoideum)
sybA [plasma membrane] (Dictyostelium discoideum)
Endophilins recruit synaptojanins to the clathrin-coated pit (Dictyostelium discoideum)
PI(4,5)P2:p-T156 AP-2:clathrin:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo:F-BAR proteins:BAR domain proteins:ARP2/3 complex:WASL:f-actin:HIP dimers:DNM:GTP [plasma membrane] (Dictyostelium discoideum)
PI(4,5)P2:p-T156 AP-2:clathrin:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo:F-BAR proteins:BAR domain proteins:ARP2/3 complex:WASL:f-actin:HIP dimers [plasma membrane] (Dictyostelium discoideum)
PI(4,5)P2:p-T156 AP-2:clathrin:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo:F-BAR proteins:BAR domain proteins [plasma membrane] (Dictyostelium discoideum)
PI(4,5)P2:ITSNs:EPS15:REPS1:clathrin:NECAPs:p-T156 AP-2:SGIP1:CLASP proteins:cargo [plasma membrane] (Dictyostelium discoideum)
CLASP proteins:cargo [plasma membrane] (Dictyostelium discoideum)
PICALM:VAMP2,3,8 [plasma membrane] (Dictyostelium discoideum)
sybA [plasma membrane] (Dictyostelium discoideum)
PI(4,5)P2:p-T156 AP-2:clathrin:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo:F-BAR proteins:BAR domain proteins:ARP2/3 complex:WASL:f-actin:HIP dimers:DNM:GTP:SYNJs [plasma membrane] (Dictyostelium discoideum)
PI(4,5)P2:p-T156 AP-2:clathrin:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo:F-BAR proteins:BAR domain proteins:ARP2/3 complex:WASL:f-actin:HIP dimers:DNM:GTP [plasma membrane] (Dictyostelium discoideum)
PI(4,5)P2:p-T156 AP-2:clathrin:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo:F-BAR proteins:BAR domain proteins:ARP2/3 complex:WASL:f-actin:HIP dimers [plasma membrane] (Dictyostelium discoideum)
PI(4,5)P2:p-T156 AP-2:clathrin:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo:F-BAR proteins:BAR domain proteins [plasma membrane] (Dictyostelium discoideum)
PI(4,5)P2:ITSNs:EPS15:REPS1:clathrin:NECAPs:p-T156 AP-2:SGIP1:CLASP proteins:cargo [plasma membrane] (Dictyostelium discoideum)
CLASP proteins:cargo [plasma membrane] (Dictyostelium discoideum)
PICALM:VAMP2,3,8 [plasma membrane] (Dictyostelium discoideum)
sybA [plasma membrane] (Dictyostelium discoideum)
SYNJ hydrolyze PI(4,5)P2 to PI(4)P (Dictyostelium discoideum)
PI(4)P:p-T156 AP-2:clathrin:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo:F-BAR proteins:BAR domain proteins:ARP2/3 complex:WASL:f-actin:HIP dimers:DNM:GTP:SYNJs [plasma membrane] (Dictyostelium discoideum)
CLASP proteins:cargo [plasma membrane] (Dictyostelium discoideum)
PICALM:VAMP2,3,8 [plasma membrane] (Dictyostelium discoideum)
sybA [plasma membrane] (Dictyostelium discoideum)
PI(4,5)P2:p-T156 AP-2:clathrin:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo:F-BAR proteins:BAR domain proteins:ARP2/3 complex:WASL:f-actin:HIP dimers:DNM:GTP:SYNJs [plasma membrane] (Dictyostelium discoideum)
PI(4,5)P2:p-T156 AP-2:clathrin:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo:F-BAR proteins:BAR domain proteins:ARP2/3 complex:WASL:f-actin:HIP dimers:DNM:GTP [plasma membrane] (Dictyostelium discoideum)
PI(4,5)P2:p-T156 AP-2:clathrin:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo:F-BAR proteins:BAR domain proteins:ARP2/3 complex:WASL:f-actin:HIP dimers [plasma membrane] (Dictyostelium discoideum)
PI(4,5)P2:p-T156 AP-2:clathrin:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo:F-BAR proteins:BAR domain proteins [plasma membrane] (Dictyostelium discoideum)
PI(4,5)P2:ITSNs:EPS15:REPS1:clathrin:NECAPs:p-T156 AP-2:SGIP1:CLASP proteins:cargo [plasma membrane] (Dictyostelium discoideum)
CLASP proteins:cargo [plasma membrane] (Dictyostelium discoideum)
PICALM:VAMP2,3,8 [plasma membrane] (Dictyostelium discoideum)
sybA [plasma membrane] (Dictyostelium discoideum)
trans-Golgi Network Vesicle Budding (Dictyostelium discoideum)
Vamp2 associated secretory vesicle to plasma membrane transport (Dictyostelium discoideum)
sybA [plasma membrane] (Dictyostelium discoideum)
External Reference Information
External Reference
UniProt:Q6TMJ9
Gene Names
sybA
Reference Genes
BioGPS Gene:8622381 sybA
dictyBase:DDB_G0280061
ENSEMBL:DDB_G0280061
KEGG Gene (Dictyostelium discoideum):DDB_G0280061 sybA
Monarch:8622381 sybA
NCBI Gene:8622381 sybA
Reference Transcript
RefSeq:XM_636157.1 sybA
Participant Of
input
PICALM binds R-SNAREs
hasComponent
PICALM:VAMP2,3,8 [plasma membrane]
output
Vamp2 associated secretory vesicle to plasma membrane transport
hasCandidate
SNAP25,STXBP2, VAMP2 [plasma membrane]
Other forms of this molecule
sybA [clathrin-coated endocytic vesicle membrane]
sybA [clathrin-coated endocytic vesicle membrane]
sybA [clathrin-coated endocytic vesicle membrane]
sybA [plasma membrane]
sybA [secretory granule membrane]
sybA [secretory granule membrane]
sybA [cytoplasmic vesicle membrane]
sybA [cytoplasmic vesicle membrane]
sybA [Golgi membrane]
sybA [Golgi membrane]
sybA [lysosomal membrane]
sybA [lysosomal membrane]
sybA [transport vesicle]
sybA [trans-Golgi network membrane]
sybA [cytosol]
sybA [azurophil granule membrane]
sybA [tertiary granule membrane]
sybA [plasma membrane]
sybA [specific granule membrane]
sybA [clathrin-sculpted glutamate transport vesicle membrane]
Inferred From
VAMP2 [plasma membrane] (Homo sapiens)
VAMP2,3,8 [plasma membrane] (Homo sapiens)
Cross References
RefSeq
XP_641249.1
PRO
Q6TMJ9
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