Reactome | H3a [nucleoplasm]

H3a [nucleoplasm]

Stable Identifier

R-DDI-427324

Type

Protein [EntityWithAccessionedSequence]

Species

Dictyostelium discoideum

Compartment

nucleoplasm

Synonyms

Me2K-10-H3F3A, O15819

Locations in the PathwayBrowser

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Gene expression (Transcription) (Dictyostelium discoideum)

- Epigenetic regulation of gene expression (Dictyostelium discoideum)
  - Negative epigenetic regulation of rRNA expression (Dictyostelium discoideum)
    - SIRT1 negatively regulates rRNA expression (Dictyostelium discoideum)
      - eNoSC deacetylates histone H3 (Dictyostelium discoideum)
        
        eNoSC [nucleoplasm] (Dictyostelium discoideum)
        
        Chromatin (H3K9me2) [nucleoplasm] (Dictyostelium discoideum)
        
        Nucleosome with H3K9me2 [nucleoplasm] (Dictyostelium discoideum)
        
        Histone H3 dimethylated at lysine-9 [nucleoplasm] (Dictyostelium discoideum)
        
        H3a [nucleoplasm] (Dictyostelium discoideum)
      - eNoSC dimethylates histone H3 at lysine-9 (Dictyostelium discoideum)
        
        Chromatin (H3K9me2) [nucleoplasm] (Dictyostelium discoideum)
        
        Nucleosome with H3K9me2 [nucleoplasm] (Dictyostelium discoideum)
        
        Histone H3 dimethylated at lysine-9 [nucleoplasm] (Dictyostelium discoideum)
        
        H3a [nucleoplasm] (Dictyostelium discoideum)
        
        eNoSC [nucleoplasm] (Dictyostelium discoideum)
        
        Chromatin (H3K9me2) [nucleoplasm] (Dictyostelium discoideum)
        
        Nucleosome with H3K9me2 [nucleoplasm] (Dictyostelium discoideum)
        
        Histone H3 dimethylated at lysine-9 [nucleoplasm] (Dictyostelium discoideum)
        
        H3a [nucleoplasm] (Dictyostelium discoideum)
- RNA Polymerase I Transcription (Dictyostelium discoideum)
  - RNA Polymerase I Promoter Clearance (Dictyostelium discoideum)
    - RNA Polymerase I Promoter Escape (Dictyostelium discoideum)
      - Elongation of pre-rRNA transcript (Dictyostelium discoideum)
        
        Chromatin (H3K9me2):CBX3 [nucleoplasm] (Dictyostelium discoideum)
        
        Chromatin (H3K9me2) [nucleoplasm] (Dictyostelium discoideum)
        
        Nucleosome with H3K9me2 [nucleoplasm] (Dictyostelium discoideum)
        
        Histone H3 dimethylated at lysine-9 [nucleoplasm] (Dictyostelium discoideum)
        
        H3a [nucleoplasm] (Dictyostelium discoideum)

External Reference Information

External Reference

UniProt:O15819

Gene Names

H3a

Reference Genes

BioGPS Gene:8616389 H3a

dictyBase:DDB_G0267402

ENSEMBL:DDB_G0267402

KEGG Gene (Dictyostelium discoideum):DDB_G0267402 H3a

Monarch:8616389 H3a

NCBI Gene:8616389 H3a

Reference Transcript

RefSeq:XM_642485.1 H3a

Participates

as a member of

Histone H3 dimethylated at lysine-9 [nucleoplasm] (Dictyostelium discoideum)

Other forms of this molecule

H3a [nucleoplasm]

Inferred From

Me2K-10-H3F3A [nucleoplasm] (Homo sapiens)

Modified Residues

Name

N6,N6-dimethyl-L-lysine at 10 (in Homo sapiens)

Coordinate

PsiMod Name

N6,N6-dimethyl-L-lysine [MOD:00084]

PsiMod Definition

A protein modification that effectively converts an L-lysine residue to N6,N6-dimethyl-L-lysine.

Cross References

RefSeq

XP_647577.1

Target Pathogen

5b2801b3be737e35a6df0ac2

PRO

O15819