Reactome | CDC6 [nucleoplasm]

CDC6 [nucleoplasm]

Stable Identifier

R-DDI-68542

Type

Protein [EntityWithAccessionedSequence]

Species

Dictyostelium discoideum

Compartment

nucleoplasm

Synonyms

Q552L8

Locations in the PathwayBrowser

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Cell Cycle (Dictyostelium discoideum)

- Cell Cycle, Mitotic (Dictyostelium discoideum)
  - Mitotic G1 phase and G1/S transition (Dictyostelium discoideum)
    - G1/S Transition (Dictyostelium discoideum)
      - Activation of the pre-replicative complex (Dictyostelium discoideum)
        
        Cdc45 associates with the pre-replicative complex at the origin (Dictyostelium discoideum)
        
        CDK:DDK:MCM10:active pre-replicative complex [nucleoplasm] (Dictyostelium discoideum)
        
        MCM10:active pre-replicative complex [nucleoplasm] (Dictyostelium discoideum)
        
        active pre-replicative complex [nucleoplasm] (Dictyostelium discoideum)
        
        CDC6:ORC:origin complex [nucleoplasm] (Dictyostelium discoideum)
        
        CDC6 [nucleoplasm] (Dictyostelium discoideum)
        
        CDK:DDK:MCM10:active pre-replicative complex:CDC45 [nucleoplasm] (Dictyostelium discoideum)
        
        CDK:DDK:MCM10:active pre-replicative complex [nucleoplasm] (Dictyostelium discoideum)
        
        MCM10:active pre-replicative complex [nucleoplasm] (Dictyostelium discoideum)
        
        active pre-replicative complex [nucleoplasm] (Dictyostelium discoideum)
        
        CDC6:ORC:origin complex [nucleoplasm] (Dictyostelium discoideum)
        
        CDC6 [nucleoplasm] (Dictyostelium discoideum)
  - S Phase (Dictyostelium discoideum)
    - Synthesis of DNA (Dictyostelium discoideum)
      - Switching of origins to a post-replicative state (Dictyostelium discoideum)
        
        CDK-mediated phosphorylation and removal of Cdc6 (Dictyostelium discoideum)
        
        Cdc6 protein is phosphorylated by CDK (Dictyostelium discoideum)
        
        CDC6 [nucleoplasm] (Dictyostelium discoideum)

External Reference Information

External Reference

UniProt:Q552L8

Reference Genes

dictyBase:DDB_G0275983

ENSEMBL:DDB_G0275983

KEGG Gene (Dictyostelium discoideum):DDB_G0275983

Participant Of

input

hasComponent

output

CDC6 protein is synthesized under the control of E2F transcription factors

Other forms of this molecule

CDC6 [cytosol]

phospho-p-CDC6 [cytosol]

phospho-p-CDC6 [nucleoplasm]

Inferred From

CDC6 [nucleoplasm] (Homo sapiens)