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CDC6 [nucleoplasm]
Stable Identifier
R-DDI-68542
Type
Protein [EntityWithAccessionedSequence]
Species
Dictyostelium discoideum
Compartment
nucleoplasm
Synonyms
Q552L8
Locations in the PathwayBrowser
Expand all
Cell Cycle (Dictyostelium discoideum)
Cell Cycle, Mitotic (Dictyostelium discoideum)
Mitotic G1 phase and G1/S transition (Dictyostelium discoideum)
G1/S Transition (Dictyostelium discoideum)
Activation of the pre-replicative complex (Dictyostelium discoideum)
CDK and DDK associate with the Mcm10:pre-replicative complex (Dictyostelium discoideum)
CDK:DDK:MCM10:active pre-replicative complex [nucleoplasm] (Dictyostelium discoideum)
MCM10:active pre-replicative complex [nucleoplasm] (Dictyostelium discoideum)
active pre-replicative complex [nucleoplasm] (Dictyostelium discoideum)
CDC6:ORC:origin complex [nucleoplasm] (Dictyostelium discoideum)
CDC6 [nucleoplasm] (Dictyostelium discoideum)
MCM10:active pre-replicative complex [nucleoplasm] (Dictyostelium discoideum)
active pre-replicative complex [nucleoplasm] (Dictyostelium discoideum)
CDC6:ORC:origin complex [nucleoplasm] (Dictyostelium discoideum)
CDC6 [nucleoplasm] (Dictyostelium discoideum)
Cdc45 associates with the pre-replicative complex at the origin (Dictyostelium discoideum)
CDK:DDK:MCM10:active pre-replicative complex [nucleoplasm] (Dictyostelium discoideum)
MCM10:active pre-replicative complex [nucleoplasm] (Dictyostelium discoideum)
active pre-replicative complex [nucleoplasm] (Dictyostelium discoideum)
CDC6:ORC:origin complex [nucleoplasm] (Dictyostelium discoideum)
CDC6 [nucleoplasm] (Dictyostelium discoideum)
CDK:DDK:MCM10:active pre-replicative complex:CDC45 [nucleoplasm] (Dictyostelium discoideum)
CDK:DDK:MCM10:active pre-replicative complex [nucleoplasm] (Dictyostelium discoideum)
MCM10:active pre-replicative complex [nucleoplasm] (Dictyostelium discoideum)
active pre-replicative complex [nucleoplasm] (Dictyostelium discoideum)
CDC6:ORC:origin complex [nucleoplasm] (Dictyostelium discoideum)
CDC6 [nucleoplasm] (Dictyostelium discoideum)
DNA polymerase alpha:primase binds at the origin (Dictyostelium discoideum)
CDK:DDK:MCM10:active pre-replicative complex:CDC45:RPA1-4 [nucleoplasm] (Dictyostelium discoideum)
CDK:DDK:MCM10:active pre-replicative complex:CDC45 [nucleoplasm] (Dictyostelium discoideum)
CDK:DDK:MCM10:active pre-replicative complex [nucleoplasm] (Dictyostelium discoideum)
MCM10:active pre-replicative complex [nucleoplasm] (Dictyostelium discoideum)
active pre-replicative complex [nucleoplasm] (Dictyostelium discoideum)
CDC6:ORC:origin complex [nucleoplasm] (Dictyostelium discoideum)
CDC6 [nucleoplasm] (Dictyostelium discoideum)
DNA polymerase epsilon binds at the origin (Dictyostelium discoideum)
CDK:DDK:MCM10:active pre-replicative complex:CDC45:RPA1-4 [nucleoplasm] (Dictyostelium discoideum)
CDK:DDK:MCM10:active pre-replicative complex:CDC45 [nucleoplasm] (Dictyostelium discoideum)
CDK:DDK:MCM10:active pre-replicative complex [nucleoplasm] (Dictyostelium discoideum)
MCM10:active pre-replicative complex [nucleoplasm] (Dictyostelium discoideum)
active pre-replicative complex [nucleoplasm] (Dictyostelium discoideum)
CDC6:ORC:origin complex [nucleoplasm] (Dictyostelium discoideum)
CDC6 [nucleoplasm] (Dictyostelium discoideum)
S Phase (Dictyostelium discoideum)
Synthesis of DNA (Dictyostelium discoideum)
Switching of origins to a post-replicative state (Dictyostelium discoideum)
CDK-mediated phosphorylation and removal of Cdc6 (Dictyostelium discoideum)
Cdc6 protein is phosphorylated by CDK (Dictyostelium discoideum)
CDC6 [nucleoplasm] (Dictyostelium discoideum)
DNA Replication (Dictyostelium discoideum)
DNA Replication Pre-Initiation (Dictyostelium discoideum)
Activation of the pre-replicative complex (Dictyostelium discoideum)
CDK and DDK associate with the Mcm10:pre-replicative complex (Dictyostelium discoideum)
CDK:DDK:MCM10:active pre-replicative complex [nucleoplasm] (Dictyostelium discoideum)
MCM10:active pre-replicative complex [nucleoplasm] (Dictyostelium discoideum)
active pre-replicative complex [nucleoplasm] (Dictyostelium discoideum)
CDC6:ORC:origin complex [nucleoplasm] (Dictyostelium discoideum)
CDC6 [nucleoplasm] (Dictyostelium discoideum)
MCM10:active pre-replicative complex [nucleoplasm] (Dictyostelium discoideum)
active pre-replicative complex [nucleoplasm] (Dictyostelium discoideum)
CDC6:ORC:origin complex [nucleoplasm] (Dictyostelium discoideum)
CDC6 [nucleoplasm] (Dictyostelium discoideum)
Cdc45 associates with the pre-replicative complex at the origin (Dictyostelium discoideum)
CDK:DDK:MCM10:active pre-replicative complex [nucleoplasm] (Dictyostelium discoideum)
MCM10:active pre-replicative complex [nucleoplasm] (Dictyostelium discoideum)
active pre-replicative complex [nucleoplasm] (Dictyostelium discoideum)
CDC6:ORC:origin complex [nucleoplasm] (Dictyostelium discoideum)
CDC6 [nucleoplasm] (Dictyostelium discoideum)
CDK:DDK:MCM10:active pre-replicative complex:CDC45 [nucleoplasm] (Dictyostelium discoideum)
CDK:DDK:MCM10:active pre-replicative complex [nucleoplasm] (Dictyostelium discoideum)
MCM10:active pre-replicative complex [nucleoplasm] (Dictyostelium discoideum)
active pre-replicative complex [nucleoplasm] (Dictyostelium discoideum)
CDC6:ORC:origin complex [nucleoplasm] (Dictyostelium discoideum)
CDC6 [nucleoplasm] (Dictyostelium discoideum)
DNA polymerase alpha:primase binds at the origin (Dictyostelium discoideum)
CDK:DDK:MCM10:active pre-replicative complex:CDC45:RPA1-4 [nucleoplasm] (Dictyostelium discoideum)
CDK:DDK:MCM10:active pre-replicative complex:CDC45 [nucleoplasm] (Dictyostelium discoideum)
CDK:DDK:MCM10:active pre-replicative complex [nucleoplasm] (Dictyostelium discoideum)
MCM10:active pre-replicative complex [nucleoplasm] (Dictyostelium discoideum)
active pre-replicative complex [nucleoplasm] (Dictyostelium discoideum)
CDC6:ORC:origin complex [nucleoplasm] (Dictyostelium discoideum)
CDC6 [nucleoplasm] (Dictyostelium discoideum)
DNA polymerase epsilon binds at the origin (Dictyostelium discoideum)
CDK:DDK:MCM10:active pre-replicative complex:CDC45:RPA1-4 [nucleoplasm] (Dictyostelium discoideum)
CDK:DDK:MCM10:active pre-replicative complex:CDC45 [nucleoplasm] (Dictyostelium discoideum)
CDK:DDK:MCM10:active pre-replicative complex [nucleoplasm] (Dictyostelium discoideum)
MCM10:active pre-replicative complex [nucleoplasm] (Dictyostelium discoideum)
active pre-replicative complex [nucleoplasm] (Dictyostelium discoideum)
CDC6:ORC:origin complex [nucleoplasm] (Dictyostelium discoideum)
CDC6 [nucleoplasm] (Dictyostelium discoideum)
Assembly of the pre-replicative complex (Dictyostelium discoideum)
CDC6 association with the ORC:origin complex (Dictyostelium discoideum)
CDC6 association with ORC:origin complexes mediated by MCM8 (Dictyostelium discoideum)
CDC6 [nucleoplasm] (Dictyostelium discoideum)
CDC6:ORC:origin complex [nucleoplasm] (Dictyostelium discoideum)
CDC6 [nucleoplasm] (Dictyostelium discoideum)
CDC6 protein is synthesized under the control of E2F transcription factors (Dictyostelium discoideum)
CDC6 [nucleoplasm] (Dictyostelium discoideum)
Mcm2-7 associates with the Cdt1:CDC6:ORC:origin complex, forming the pre-replicative complex (preRC) (Dictyostelium discoideum)
CDT1:CDC6:ORC:origin complex [nucleoplasm] (Dictyostelium discoideum)
CDC6:ORC:origin complex [nucleoplasm] (Dictyostelium discoideum)
CDC6 [nucleoplasm] (Dictyostelium discoideum)
pre-replicative complex [nucleoplasm] (Dictyostelium discoideum)
CDT1:CDC6:ORC:origin complex [nucleoplasm] (Dictyostelium discoideum)
CDC6:ORC:origin complex [nucleoplasm] (Dictyostelium discoideum)
CDC6 [nucleoplasm] (Dictyostelium discoideum)
Synthesis of DNA (Dictyostelium discoideum)
Switching of origins to a post-replicative state (Dictyostelium discoideum)
CDK-mediated phosphorylation and removal of Cdc6 (Dictyostelium discoideum)
Cdc6 protein is phosphorylated by CDK (Dictyostelium discoideum)
CDC6 [nucleoplasm] (Dictyostelium discoideum)
External Reference Information
External Reference
UniProt:Q552L8
Reference Genes
BioGPS Gene:8620247
dictyBase:DDB_G0275983
ENSEMBL:DDB_G0275983
KEGG Gene (Dictyostelium discoideum):DDB_G0275983
Monarch:8620247
NCBI Gene:8620247
Reference Transcript
RefSeq:XM_638272.1
Participant Of
input
CDC6 association with ORC:origin complexes mediated by MCM8
Cdc6 protein is phosphorylated by CDK
hasComponent
CDC6:ORC:origin complex [nucleoplasm]
pre-replicative complex (Orc1-minus) [nucleoplasm]
output
CDC6 protein is synthesized under the control of E2F transcription factors
Other forms of this molecule
phospho-p-CDC6 [nucleoplasm]
phospho-p-CDC6 [cytosol]
CDC6 [cytosol]
Inferred From
CDC6 [nucleoplasm] (Homo sapiens)
Cross References
RefSeq
XP_643364.1
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