Reactome | rpl15-2 [cytosol]

rpl15-2 [cytosol]

Stable Identifier

R-DDI-72416

Type

Protein [EntityWithAccessionedSequence]

Species

Dictyostelium discoideum

Compartment

cytosol

Synonyms

RPL15, Q86K01

Locations in the PathwayBrowser

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Metabolism of RNA (Dictyostelium discoideum)

- Nonsense-Mediated Decay (NMD) (Dictyostelium discoideum)
  - Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC) (Dictyostelium discoideum)
    - SMG1 phosphorylates UPF1 (enhanced by Exon Junction Complex) (Dictyostelium discoideum)
      - SMG1:Phosphorylated UPF1:EJC:Translated mRNP [cytosol] (Dictyostelium discoideum)
        
        Translated mRNA Complex with Premature Termination Codon Preceding Exon Junction [cytosol] (Dictyostelium discoideum)
        
        80S ribosome [cytosol] (Dictyostelium discoideum)
        
        60S ribosomal complex [cytosol] (Dictyostelium discoideum)
        
        rpl15-2 [cytosol] (Dictyostelium discoideum)
      - SMG1:UPF1:EJC:Translated mRNP [cytosol] (Dictyostelium discoideum)
        
        Translated mRNA Complex with Premature Termination Codon Preceding Exon Junction [cytosol] (Dictyostelium discoideum)
        
        80S ribosome [cytosol] (Dictyostelium discoideum)
        
        60S ribosomal complex [cytosol] (Dictyostelium discoideum)
        
        rpl15-2 [cytosol] (Dictyostelium discoideum)
    - UPF1 binds an mRNP with a termination codon preceding an Exon Junction Complex (Dictyostelium discoideum)
      - SMG1:UPF1:EJC:Translated mRNP [cytosol] (Dictyostelium discoideum)
        
        Translated mRNA Complex with Premature Termination Codon Preceding Exon Junction [cytosol] (Dictyostelium discoideum)
        
        80S ribosome [cytosol] (Dictyostelium discoideum)
        
        60S ribosomal complex [cytosol] (Dictyostelium discoideum)
        
        rpl15-2 [cytosol] (Dictyostelium discoideum)
      - Translated mRNA Complex with Premature Termination Codon Preceding Exon Junction [cytosol] (Dictyostelium discoideum)
        
        80S ribosome [cytosol] (Dictyostelium discoideum)
        
        60S ribosomal complex [cytosol] (Dictyostelium discoideum)
        
        rpl15-2 [cytosol] (Dictyostelium discoideum)
  - Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC) (Dictyostelium discoideum)
    - Formation of UPF1:eRF3 complex on mRNA with a premature termination codon and no Exon Junction Complex (Dictyostelium discoideum)
      - Translated mRNA Complex with Premature Termination Codon Not Preceding Exon Junction [cytosol] (Dictyostelium discoideum)
        
        80S ribosome [cytosol] (Dictyostelium discoideum)
        
        60S ribosomal complex [cytosol] (Dictyostelium discoideum)
        
        rpl15-2 [cytosol] (Dictyostelium discoideum)
      - UPF1:eRF3 Complex on Translated mRNA [cytosol] (Dictyostelium discoideum)
        
        Translated mRNA Complex with Premature Termination Codon Not Preceding Exon Junction [cytosol] (Dictyostelium discoideum)
        
        80S ribosome [cytosol] (Dictyostelium discoideum)
        
        60S ribosomal complex [cytosol] (Dictyostelium discoideum)
        
        rpl15-2 [cytosol] (Dictyostelium discoideum)

External Reference Information

External Reference

UniProt:Q86K01

Gene Names

rpl15-2

Reference Genes

BioGPS Gene:8618739 rpl15-2

BioGPS Gene:8619237 rpl15-2

dictyBase:DDB_G0272893

ENSEMBL:DDB_G0272893

KEGG Gene (Dictyostelium discoideum):DDB_G0272893 rpl15-2

KEGG Gene (Dictyostelium discoideum):DDB_G0273983 rpl15-2

Monarch:8618739 rpl15-2

Monarch:8619237 rpl15-2

NCBI Gene:8618739 rpl15-2

NCBI Gene:8619237 rpl15-2

Reference Transcript

Participates

as a component of

Inferred From

RPL15 [cytosol] (Homo sapiens)

Cross References

RefSeq

XP_645064.1, XP_644350.2

PRO

Q86K01

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