Reactome | FCHO1 [cytosol]

FCHO1 [cytosol]

Stable Identifier

R-DDI-8862257-4

Type

Protein [EntityWithAccessionedSequence]

Species

Dictyostelium discoideum

Compartment

cytosol

Synonyms

Q75JD4

Locations in the PathwayBrowser

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Vesicle-mediated transport (Dictyostelium discoideum)

- Membrane Trafficking (Dictyostelium discoideum)
  - Clathrin-mediated endocytosis (Dictyostelium discoideum)
    - AAK1 phosphorylates AP-2 mu subunit at T156 (Dictyostelium discoideum)
      - PI(4,5)P2:AP-2:clathrin:FCHO1,2:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1 [plasma membrane] (Dictyostelium discoideum)
        
        PI(4,5)P2:AP-2:clathrin:FCHO1,2:ITSNs:EPS15:REPS1:SGIP1 [plasma membrane] (Dictyostelium discoideum)
        
        FCHO1,2 dimer [cytosol] (Dictyostelium discoideum)
        
        FCHO1 dimer [cytosol] (Dictyostelium discoideum)
        
        Homologues of FCHO1 [cytosol] (Dictyostelium discoideum)
        
        FCHO1 [cytosol] (Dictyostelium discoideum)
      - PI(4,5)P2:p-T156 AP-2:clathrin:FCHO1,2:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1 [plasma membrane] (Dictyostelium discoideum)
        
        FCHO1,2 dimer [cytosol] (Dictyostelium discoideum)
        
        FCHO1 dimer [cytosol] (Dictyostelium discoideum)
        
        Homologues of FCHO1 [cytosol] (Dictyostelium discoideum)
        
        FCHO1 [cytosol] (Dictyostelium discoideum)
    - Clathrin-associated PIK3C2A phosphorylates PI(4)P to PI(3,4)P2 (Dictyostelium discoideum)
      - PI(4,5)P2:p-T156 AP-2:clathrin:FCHO1,2:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo:PIK3C2A [plasma membrane] (Dictyostelium discoideum)
        
        PI(4,5)P2:p-T156 AP-2:clathrin:FCHO1,2:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo [plasma membrane] (Dictyostelium discoideum)
        
        PI(4,5)P2:p-T156 AP-2:clathrin:FCHO1,2:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1 [plasma membrane] (Dictyostelium discoideum)
        
        FCHO1,2 dimer [cytosol] (Dictyostelium discoideum)
        
        FCHO1 dimer [cytosol] (Dictyostelium discoideum)
        
        Homologues of FCHO1 [cytosol] (Dictyostelium discoideum)
        
        FCHO1 [cytosol] (Dictyostelium discoideum)

External Reference Information

External Reference

UniProt:Q75JD4

Reference Genes

BioGPS Gene:8618119

dictyBase:DDB_G0271676

ENSEMBL:DDB_G0271676

KEGG Gene (Dictyostelium discoideum):DDB_G0271676

Monarch:8618119

NCBI Gene:8618119

Reference Transcript

RefSeq:XM_640399.1

Participates

as a member of

Homologues of FCHO1 [cytosol] (Dictyostelium discoideum)

Other forms of this molecule

PACSIN2 [cytosol]

PACSIN1 [cytosol]

PACSIN3 [cytosol]

FCHO2 [cytosol]

Inferred From

FCHO1 [cytosol] (Homo sapiens)

Cross References

RefSeq

XP_645491.1

PRO

Q75JD4

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