Reactome | Phs [nucleoplasm]

Phs [nucleoplasm]

Stable Identifier

R-DME-1027428-5

Type

Protein [EntityWithAccessionedSequence]

Species

Drosophila melanogaster

Compartment

nucleoplasm

Synonyms

ZNF30, Q9VUS0

Locations in the PathwayBrowser

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Gene expression (Transcription) (Drosophila melanogaster)

- Epigenetic regulation of gene expression (Drosophila melanogaster)
  - Regulation of endogenous retroelements (Drosophila melanogaster)
    - Regulation of endogenous retroelements by KRAB-ZFP proteins (Drosophila melanogaster)
      - ATF7IP:SETDB1 binds SUMO2-6K-TRIM28:KRAB-ZFP:retroelement chromatin (Drosophila melanogaster)
        
        ATF7IP:SETDB1:SUMO2-6K-TRIM28:KRAB-ZFP:retroelement chromatin [nucleoplasm] (Drosophila melanogaster)
        
        KRAB-ZFP:retroelement chromatin [nucleoplasm] (Drosophila melanogaster)
        
        KRAB-ZFPs that bind, repress retroelements [nucleoplasm] (Drosophila melanogaster)
        
        Homologues of ZNF30 [nucleoplasm] (Drosophila melanogaster)
        
        Phs [nucleoplasm] (Drosophila melanogaster)
        
        SUMO2-6K-TRIM28:KRAB-ZFP:retroelement chromatin [nucleoplasm] (Drosophila melanogaster)
        
        KRAB-ZFP:retroelement chromatin [nucleoplasm] (Drosophila melanogaster)
        
        KRAB-ZFPs that bind, repress retroelements [nucleoplasm] (Drosophila melanogaster)
        
        Homologues of ZNF30 [nucleoplasm] (Drosophila melanogaster)
        
        Phs [nucleoplasm] (Drosophila melanogaster)
      - CBX5 (HP-1alpha) binds TRIM28 (KAP1) in SUMO2-6K-TRIM28:KRAB-ZFP:retroelement chromatin (Drosophila melanogaster)
        
        CBX5:SUMO2-6K-TRIM28:KRAB-ZFP:retroelement [nucleoplasm] (Drosophila melanogaster)
        
        SUMO2-6K-TRIM28:KRAB-ZFP:retroelement chromatin [nucleoplasm] (Drosophila melanogaster)
        
        KRAB-ZFP:retroelement chromatin [nucleoplasm] (Drosophila melanogaster)
        
        KRAB-ZFPs that bind, repress retroelements [nucleoplasm] (Drosophila melanogaster)
        
        Homologues of ZNF30 [nucleoplasm] (Drosophila melanogaster)
        
        Phs [nucleoplasm] (Drosophila melanogaster)
        
        SUMO2-6K-TRIM28:KRAB-ZFP:retroelement chromatin [nucleoplasm] (Drosophila melanogaster)
        
        KRAB-ZFP:retroelement chromatin [nucleoplasm] (Drosophila melanogaster)
        
        KRAB-ZFPs that bind, repress retroelements [nucleoplasm] (Drosophila melanogaster)
        
        Homologues of ZNF30 [nucleoplasm] (Drosophila melanogaster)
        
        Phs [nucleoplasm] (Drosophila melanogaster)
      - KRAB-ZFP binds retroelement DNA in chromatin (Drosophila melanogaster)
        
        KRAB-ZFP:retroelement chromatin [nucleoplasm] (Drosophila melanogaster)
        
        KRAB-ZFPs that bind, repress retroelements [nucleoplasm] (Drosophila melanogaster)
        
        Homologues of ZNF30 [nucleoplasm] (Drosophila melanogaster)
        
        Phs [nucleoplasm] (Drosophila melanogaster)
        
        KRAB-ZFPs that bind, repress retroelements [nucleoplasm] (Drosophila melanogaster)
        
        Homologues of ZNF30 [nucleoplasm] (Drosophila melanogaster)
        
        Phs [nucleoplasm] (Drosophila melanogaster)
      - SETDB1 in ATF7IP:SETDB1:SUMO2-6K-TRIM28:KRAB-ZFP:retroelement trimethylates lysine-9 of histone H3 in nucleosomes (Drosophila melanogaster)
        
        ATF7IP:SETDB1:SUMO2-6K-TRIM28:KRAB-ZFP:retroelement chromatin [nucleoplasm] (Drosophila melanogaster)
        
        KRAB-ZFP:retroelement chromatin [nucleoplasm] (Drosophila melanogaster)
        
        KRAB-ZFPs that bind, repress retroelements [nucleoplasm] (Drosophila melanogaster)
        
        Homologues of ZNF30 [nucleoplasm] (Drosophila melanogaster)
        
        Phs [nucleoplasm] (Drosophila melanogaster)
        
        ATF7IP:SETDB1:SUMO2-6K-TRIM28:KRAB-ZFP:retroelement chromatin with H3K9me3 [nucleoplasm] (Drosophila melanogaster)
        
        KRAB-ZFP:retroelement chromatin with H3K9me3 [nucleoplasm] (Drosophila melanogaster)
        
        KRAB-ZFPs that bind, repress retroelements [nucleoplasm] (Drosophila melanogaster)
        
        Homologues of ZNF30 [nucleoplasm] (Drosophila melanogaster)
        
        Phs [nucleoplasm] (Drosophila melanogaster)
- RNA Polymerase II Transcription (Drosophila melanogaster)
  - Generic Transcription Pathway (Drosophila melanogaster)
    - KRAB-ZNF / KAP Interaction (Drosophila melanogaster)
      - KRAB-ZNF / KAP Complex [nucleoplasm] (Drosophila melanogaster)
        
        KRAB-ZNF [nucleoplasm] (Drosophila melanogaster)
        
        Homologues of ZNF30 [nucleoplasm] (Drosophila melanogaster)
        
        Phs [nucleoplasm] (Drosophila melanogaster)
      - KRAB-ZNF [nucleoplasm] (Drosophila melanogaster)
        
        Homologues of ZNF30 [nucleoplasm] (Drosophila melanogaster)
        
        Phs [nucleoplasm] (Drosophila melanogaster)

External Reference Information

External Reference

UniProt:Q9VUS0

Gene Names

Phs

Reference Genes

BioGPS Gene:39697 Phs

CTD Gene:39697 Phs

ENSEMBL:FBgn0036522

FlyBase:FBgn0036522

KEGG:dme:Dmel_CG7372 Phs

Monarch:39697 Phs

NCBI Gene:39697 Phs

UCSC:Q9VUS0 Phs

Reference Transcript

RefSeq:NM_140532.3 Phs

Other Identifiers

142544_at

151615_at

1636156_at

39697

GO:0000122

GO:0000977

GO:0000978

GO:0000981

GO:0003677

GO:0003700

GO:0005634

GO:0006355

GO:0006357

GO:0043226

GO:0140110

Participates

as a member of

Homologues of ZNF30 [nucleoplasm] (Drosophila melanogaster)

Other forms of this molecule

Phs [nucleoplasm]

phospho-Phs [nucleoplasm]

Phs [nucleoplasm]

Inferred From

ZNF30 [nucleoplasm] (Homo sapiens)

Cross References

RefSeq

NP_648789.3

ENSEMBL

FBpp0075323, FBtr0075570