TOR signaling pathway

Stable Identifier
R-DME-110523
Type
Pathway
Species
Drosophila melanogaster
ReviewStatus
5/5
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The target of rapamycin (TOR) proteins are large protein kinases, evolutionarily conserved from yeast to humans. Under optimal nutritional conditions, TOR propagates the insulin-like signal to downstream effectors of cell growth such as D4EBP and DS6K. When nutrients are deficient, TOR transmits no signal and insulin signaling is inhibited.


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