Reactome | Ghost homologue of HBEGF(63-148) [extracellular region]

Ghost homologue of HBEGF(63-148) [extracellular region]

Stable Identifier

R-DME-1233234

Type

Genes and Transcripts [GenomeEncodedEntity]

Species

Drosophila melanogaster

Compartment

extracellular region

Locations in the PathwayBrowser

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Signal Transduction (Drosophila melanogaster)

- MAPK family signaling cascades (Drosophila melanogaster)
  - MAPK1/MAPK3 signaling (Drosophila melanogaster)
    - RAF/MAP kinase cascade (Drosophila melanogaster)
      - RAS GEFs promote RAS nucleotide exchange (Drosophila melanogaster)
        
        RAS GEFs [plasma membrane] (Drosophila melanogaster)
        
        GRB2:SOS1:HB-EGF:p-6Y-EGFR [plasma membrane] (Drosophila melanogaster)
        
        HB-EGF:p-6Y-EGFR dimer [plasma membrane] (Drosophila melanogaster)
        
        HB-EGF:p-6Y-EGFR [plasma membrane] (Drosophila melanogaster)
        
        Ghost homologue of HBEGF(63-148) [extracellular region] (Drosophila melanogaster)
- Signaling by GPCR (Drosophila melanogaster)
  - GPCR downstream signalling (Drosophila melanogaster)
    - G alpha (q) signalling events (Drosophila melanogaster)
      - Gastrin-CREB signalling pathway via PKC and MAPK (Drosophila melanogaster)
        
        EGFR Transactivation by Gastrin (Drosophila melanogaster)
        
        SOS1-mediated nucleotide exchange of RAS (HB-EFG-initiated) (Drosophila melanogaster)
        
        GRB2:SOS1:HB-EGF:p-6Y-EGFR [plasma membrane] (Drosophila melanogaster)
        
        HB-EGF:p-6Y-EGFR dimer [plasma membrane] (Drosophila melanogaster)
        
        HB-EGF:p-6Y-EGFR [plasma membrane] (Drosophila melanogaster)
        
        Ghost homologue of HBEGF(63-148) [extracellular region] (Drosophila melanogaster)

Participates

as a component of

HB-EGF:p-6Y-EGFR [plasma membrane] (Drosophila melanogaster)

Inferred From

HBEGF(63-148) [extracellular region] (Homo sapiens)

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