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Synj [cytosol]
Stable Identifier
R-DME-1604634
Type
Protein [EntityWithAccessionedSequence]
Species
Drosophila melanogaster
Compartment
cytosol
Synonyms
SYNJ1, Q5U0V7
Locations in the PathwayBrowser
Expand all
Metabolism (Drosophila melanogaster)
Inositol phosphate metabolism (Drosophila melanogaster)
Synthesis of IP2, IP, and Ins in the cytosol (Drosophila melanogaster)
I(1,4,5)P3 is dephosphorylated to I(1,4)P2 by INPP5(4) in the cytosol (Drosophila melanogaster)
INPP5(4) [cytosol] (Drosophila melanogaster)
Synj [cytosol] (Drosophila melanogaster)
Synthesis of IP3 and IP4 in the cytosol (Drosophila melanogaster)
I(1,3,4,5)P4 is dephosphorylated to I(1,3,4)P3 by INPP5[3]/ITPK1 in the cytosol (Drosophila melanogaster)
INPP5(4) [cytosol] (Drosophila melanogaster)
Synj [cytosol] (Drosophila melanogaster)
Metabolism of lipids (Drosophila melanogaster)
Phospholipid metabolism (Drosophila melanogaster)
PI Metabolism (Drosophila melanogaster)
Synthesis of PIPs at the plasma membrane (Drosophila melanogaster)
PI(3,5)P2 is dephosphorylated to PI3P by SYNJ at the plasma membrane (Drosophila melanogaster)
SYNJs,OCRL [cytosol] (Drosophila melanogaster)
Synj [cytosol] (Drosophila melanogaster)
PI(3,5)P2 is dephosphorylated to PI5P by SYNJ/MTMs at the plasma membrane (Drosophila melanogaster)
MTM1,MTMR1,MTMR3,MTMR6,MTMR14,SYNJ1,SYNJ2 [cytosol] (Drosophila melanogaster)
Synj [cytosol] (Drosophila melanogaster)
PI(4,5)P2 is dephosphorylated to PI4P by SYNJ/INPP5[1] at the plasma membrane (Drosophila melanogaster)
SYNJ/INPP5(1) [cytosol] (Drosophila melanogaster)
Synj [cytosol] (Drosophila melanogaster)
PI3P is dephosphorylated to PI by SYNJ/MTMs at the plasma membrane (Drosophila melanogaster)
MTM1,MTMR1,MTMR3,MTMR6,MTMR14,SYNJ1,SYNJ2 [cytosol] (Drosophila melanogaster)
Synj [cytosol] (Drosophila melanogaster)
PI4P is dephosphorylated to PI by SYNJ at the plasma membrane (Drosophila melanogaster)
SYNJs,OCRL [cytosol] (Drosophila melanogaster)
Synj [cytosol] (Drosophila melanogaster)
Vesicle-mediated transport (Drosophila melanogaster)
Membrane Trafficking (Drosophila melanogaster)
Clathrin-mediated endocytosis (Drosophila melanogaster)
Auxilin recruits HSPA8:ATP to the clathrin-coated vesicle (Drosophila melanogaster)
PI(4)P:p-T156 AP-2:clathrin:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo:F-BAR proteins:BAR domain proteins:ARP2/3 complex:WASL:f-actin:HIP dimers:DNM:GDP:SYNJs:auxilin [clathrin-coated endocytic vesicle membrane] (Drosophila melanogaster)
SYNJs,OCRL [cytosol] (Drosophila melanogaster)
Synj [cytosol] (Drosophila melanogaster)
PI(4)P:p-T156 AP-2:clathrin:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo:F-BAR proteins:BAR domain proteins:ARP2/3 complex:WASL:f-actin:HIP dimers:DNM:GDP:SYNJs:auxilin:HSPA8:ATP [clathrin-coated endocytic vesicle membrane] (Drosophila melanogaster)
SYNJs,OCRL [cytosol] (Drosophila melanogaster)
Synj [cytosol] (Drosophila melanogaster)
Dynamin-mediated GTP hydrolysis promotes vesicle scission (Drosophila melanogaster)
PI(4)P:p-T156 AP-2:clathrin:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo:F-BAR proteins:BAR domain proteins:ARP2/3 complex:WASL:f-actin:HIP dimers:DNM:GDP:SYNJs [clathrin-coated endocytic vesicle membrane] (Drosophila melanogaster)
SYNJs,OCRL [cytosol] (Drosophila melanogaster)
Synj [cytosol] (Drosophila melanogaster)
PI(4)P:p-T156 AP-2:clathrin:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo:F-BAR proteins:BAR domain proteins:ARP2/3 complex:WASL:f-actin:HIP dimers:DNM:GTP:SYNJs [plasma membrane] (Drosophila melanogaster)
SYNJs,OCRL [cytosol] (Drosophila melanogaster)
Synj [cytosol] (Drosophila melanogaster)
Endophilins recruit synaptojanins to the clathrin-coated pit (Drosophila melanogaster)
PI(4,5)P2:p-T156 AP-2:clathrin:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo:F-BAR proteins:BAR domain proteins:ARP2/3 complex:WASL:f-actin:HIP dimers:DNM:GTP:SYNJs [plasma membrane] (Drosophila melanogaster)
SYNJs,OCRL [cytosol] (Drosophila melanogaster)
Synj [cytosol] (Drosophila melanogaster)
SYNJs,OCRL [cytosol] (Drosophila melanogaster)
Synj [cytosol] (Drosophila melanogaster)
HSPA8-mediated ATP hydrolysis promotes vesicle uncoating (Drosophila melanogaster)
PI(4)P:p-T156 AP-2:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo:F-BAR proteins:BAR domain proteins:ARP2/3 complex:WASL:f-actin:HIP dimers:DNM:GDP:SYNJs:auxilin [clathrin-coated endocytic vesicle membrane] (Drosophila melanogaster)
SYNJs,OCRL [cytosol] (Drosophila melanogaster)
Synj [cytosol] (Drosophila melanogaster)
PI(4)P:p-T156 AP-2:clathrin:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo:F-BAR proteins:BAR domain proteins:ARP2/3 complex:WASL:f-actin:HIP dimers:DNM:GDP:SYNJs:auxilin:HSPA8:ATP [clathrin-coated endocytic vesicle membrane] (Drosophila melanogaster)
SYNJs,OCRL [cytosol] (Drosophila melanogaster)
Synj [cytosol] (Drosophila melanogaster)
RAB5 and GAPVD1 bind AP-2 (Drosophila melanogaster)
PI(4)P:p-T156 AP-2:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo:F-BAR proteins:BAR domain proteins:ARP2/3 complex:WASL:f-actin:HIP dimers:DNM:GDP:SYNJs:auxilin [clathrin-coated endocytic vesicle membrane] (Drosophila melanogaster)
PI(4)P:p-T156 AP-2:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo:F-BAR proteins:BAR domain proteins:ARP2/3 complex:WASL:f-actin:HIP dimers:DNM:GDP:SYNJs:auxilin [clathrin-coated endocytic vesicle membrane] (Drosophila melanogaster)
SYNJs,OCRL [cytosol] (Drosophila melanogaster)
Synj [cytosol] (Drosophila melanogaster)
SYNJ hydrolyze PI(4,5)P2 to PI(4)P (Drosophila melanogaster)
PI(4)P:p-T156 AP-2:clathrin:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo:F-BAR proteins:BAR domain proteins:ARP2/3 complex:WASL:f-actin:HIP dimers:DNM:GTP:SYNJs [plasma membrane] (Drosophila melanogaster)
SYNJs,OCRL [cytosol] (Drosophila melanogaster)
Synj [cytosol] (Drosophila melanogaster)
PI(4,5)P2:p-T156 AP-2:clathrin:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo:F-BAR proteins:BAR domain proteins:ARP2/3 complex:WASL:f-actin:HIP dimers:DNM:GTP:SYNJs [plasma membrane] (Drosophila melanogaster)
SYNJs,OCRL [cytosol] (Drosophila melanogaster)
Synj [cytosol] (Drosophila melanogaster)
SYNJs,OCRL [cytosol] (Drosophila melanogaster)
Synj [cytosol] (Drosophila melanogaster)
External Reference Information
External Reference
UniProt:Q5U0V7
Gene Names
Synj
Reference Genes
BioGPS Gene:37517 Synj
ENSEMBL:FBgn0034691
Flybase:FBgn0034691
KEGG Gene (Drosophila melanogaster):Dmel_CG6562 Synj
Monarch:37517 Synj
NCBI Gene:37517 Synj
UCSC:Q5U0V7 Synj
Reference Transcript
RefSeq:NM_166505.1 Synj
RefSeq:NM_001259525.1 Synj
RefSeq:NM_130462.4 Synj
Other Identifiers
141600_at
1631427_s_at
37517
GO:0003676
GO:0003824
GO:0004438
GO:0004439
GO:0005764
GO:0005773
GO:0005776
GO:0005975
GO:0006629
GO:0006914
GO:0012506
GO:0016192
GO:0016787
GO:0016791
GO:0023052
GO:0034330
GO:0034595
GO:0043195
GO:0043226
GO:0043812
GO:0044754
GO:0045879
GO:0046855
GO:0046856
GO:0048488
GO:0048790
GO:0050803
GO:0061174
GO:0098793
GO:0150007
GO:0150008
GO:2000786
Participates
as a member of
INPP5(4) [cytosol] (Drosophila melanogaster)
SYNJs,OCRL [cytosol] (Drosophila melanogaster)
MTM1,MTMR1,MTMR3,MTMR6,MTMR14,SYNJ1,SYNJ2 [cytosol] (Drosophila melanogaster)
SYNJ/INPP5(1) [cytosol] (Drosophila melanogaster)
Other forms of this molecule
Synj [cytosol]
Inferred From
SYNJ1 [cytosol]
(Homo sapiens)
Cross References
RefSeq
NP_569729.1
,
NP_001246454.1
,
NP_726155.1
Flybase
FBgn0034691
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