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mTor [cytosol]
Stable Identifier
R-DME-165662
Type
Protein [EntityWithAccessionedSequence]
Species
Drosophila melanogaster
Compartment
cytosol
Synonyms
MTOR, Q9VK45
Locations in the PathwayBrowser
Expand all
Autophagy (Drosophila melanogaster)
Macroautophagy (Drosophila melanogaster)
Active MTORC1 binds the ULK1 complex (Drosophila melanogaster)
Active mTORC1 complex [lysosomal membrane] (Drosophila melanogaster)
mTORC1:Ragulator:RagA,B:GTP:RagC,D:GDP:SLC38A9 [lysosomal membrane] (Drosophila melanogaster)
mTORC1 [cytosol] (Drosophila melanogaster)
mTor [cytosol] (Drosophila melanogaster)
MTORC1:RHEB:GTP:ULK1:ATG13:RB1CC1:ATG101 [lysosomal membrane] (Drosophila melanogaster)
Active mTORC1 complex [lysosomal membrane] (Drosophila melanogaster)
mTORC1:Ragulator:RagA,B:GTP:RagC,D:GDP:SLC38A9 [lysosomal membrane] (Drosophila melanogaster)
mTORC1 [cytosol] (Drosophila melanogaster)
mTor [cytosol] (Drosophila melanogaster)
Active MTORC1 phosphorylates ULK1 (Drosophila melanogaster)
MTORC1:RHEB:GTP:ULK1:ATG13:RB1CC1:ATG101 [lysosomal membrane] (Drosophila melanogaster)
Active mTORC1 complex [lysosomal membrane] (Drosophila melanogaster)
mTORC1:Ragulator:RagA,B:GTP:RagC,D:GDP:SLC38A9 [lysosomal membrane] (Drosophila melanogaster)
mTORC1 [cytosol] (Drosophila melanogaster)
mTor [cytosol] (Drosophila melanogaster)
MTORC1:RHEB:GTP:p-S758-ULK1:ATG13:RB1CC1:ATG101 [lysosomal membrane] (Drosophila melanogaster)
Active mTORC1 complex [lysosomal membrane] (Drosophila melanogaster)
mTORC1:Ragulator:RagA,B:GTP:RagC,D:GDP:SLC38A9 [lysosomal membrane] (Drosophila melanogaster)
mTORC1 [cytosol] (Drosophila melanogaster)
mTor [cytosol] (Drosophila melanogaster)
mTor [cytosol] (Drosophila melanogaster)
MTORC1 dissociates from ULK complex (Drosophila melanogaster)
MTORC1 with p-S722,S792-RPTOR:RHEB:GTP:p-S758-ULK1:ATG13:RB1CC1:ATG101 [lysosomal membrane] (Drosophila melanogaster)
mTORC1 with p-S722,S792-RPTOR:Ragulator:Rag:GNP:RHEB:GTP [lysosomal membrane] (Drosophila melanogaster)
mTORC1 with p-RPTOR:Ragulator:Rag:GNP [lysosomal membrane] (Drosophila melanogaster)
mTORC1 with p-S722,S792-RPTOR [cytosol] (Drosophila melanogaster)
mTor [cytosol] (Drosophila melanogaster)
mTORC1 with p-S722,S792-RPTOR:Ragulator:Rag:GNP:RHEB:GTP [lysosomal membrane] (Drosophila melanogaster)
mTORC1 with p-RPTOR:Ragulator:Rag:GNP [lysosomal membrane] (Drosophila melanogaster)
mTORC1 with p-S722,S792-RPTOR [cytosol] (Drosophila melanogaster)
mTor [cytosol] (Drosophila melanogaster)
Rheb in the MTORC1 complex hydrolyses GTP (Drosophila melanogaster)
Active mTORC1 complex [lysosomal membrane] (Drosophila melanogaster)
mTORC1:Ragulator:RagA,B:GTP:RagC,D:GDP:SLC38A9 [lysosomal membrane] (Drosophila melanogaster)
mTORC1 [cytosol] (Drosophila melanogaster)
mTor [cytosol] (Drosophila melanogaster)
mTORC1:Ragulator:Rag:GNP:RHEB:GDP [lysosomal membrane] (Drosophila melanogaster)
mTORC1:Ragulator:RagA,B:GTP:RagC,D:GDP:SLC38A9 [lysosomal membrane] (Drosophila melanogaster)
mTORC1 [cytosol] (Drosophila melanogaster)
mTor [cytosol] (Drosophila melanogaster)
p-AMPK:AMP phosphorylates Raptor in the MTORC1 complex (Drosophila melanogaster)
MTORC1 with p-S722,S792-RPTOR:RHEB:GTP:p-S758-ULK1:ATG13:RB1CC1:ATG101 [lysosomal membrane] (Drosophila melanogaster)
mTORC1 with p-S722,S792-RPTOR:Ragulator:Rag:GNP:RHEB:GTP [lysosomal membrane] (Drosophila melanogaster)
mTORC1 with p-RPTOR:Ragulator:Rag:GNP [lysosomal membrane] (Drosophila melanogaster)
mTORC1 with p-S722,S792-RPTOR [cytosol] (Drosophila melanogaster)
mTor [cytosol] (Drosophila melanogaster)
MTORC1:RHEB:GTP:p-S758-ULK1:ATG13:RB1CC1:ATG101 [lysosomal membrane] (Drosophila melanogaster)
Active mTORC1 complex [lysosomal membrane] (Drosophila melanogaster)
mTORC1:Ragulator:RagA,B:GTP:RagC,D:GDP:SLC38A9 [lysosomal membrane] (Drosophila melanogaster)
mTORC1 [cytosol] (Drosophila melanogaster)
mTor [cytosol] (Drosophila melanogaster)
Cellular responses to stimuli (Drosophila melanogaster)
Cellular responses to mechanical stimuli (Drosophila melanogaster)
Response of endothelial cells to shear stress (Drosophila melanogaster)
High laminar flow shear stress activates signaling by PIEZO1 and PECAM1:CDH5:KDR in endothelial cells (Drosophila melanogaster)
mTORC2 phosphorylates AKT1 on serine-473 (Drosophila melanogaster)
TORC2 complex [cytosol] (Drosophila melanogaster)
mTor [cytosol] (Drosophila melanogaster)
mTor [cytosol] (Drosophila melanogaster)
Cellular responses to stress (Drosophila melanogaster)
Cellular response to starvation (Drosophila melanogaster)
Amino acids regulate mTORC1 (Drosophila melanogaster)
RRAGA,B hydrolyzes GTP (Drosophila melanogaster)
v-ATPase:Ragulator:RRAGA,B:GDP:RRAGC,D:GDP:mTORC1:RHEB:GTP [lysosomal membrane] (Drosophila melanogaster)
mTORC1 [cytosol] (Drosophila melanogaster)
mTor [cytosol] (Drosophila melanogaster)
v-ATPase:Ragulator:RRAGA,B:GTP:RRAGC,D:GDP:mTORC1:RHEB:GTP [lysosomal membrane] (Drosophila melanogaster)
v-ATPase:Ragulator:RRAGA,B:GTP:RRAGC,D:GDP:mTORC1 [lysosomal membrane] (Drosophila melanogaster)
mTORC1 [cytosol] (Drosophila melanogaster)
mTor [cytosol] (Drosophila melanogaster)
mTORC1 binds RHEB:GTP (Drosophila melanogaster)
v-ATPase:Ragulator:RRAGA,B:GTP:RRAGC,D:GDP:mTORC1 [lysosomal membrane] (Drosophila melanogaster)
mTORC1 [cytosol] (Drosophila melanogaster)
mTor [cytosol] (Drosophila melanogaster)
v-ATPase:Ragulator:RRAGA,B:GTP:RRAGC,D:GDP:mTORC1:RHEB:GTP [lysosomal membrane] (Drosophila melanogaster)
v-ATPase:Ragulator:RRAGA,B:GTP:RRAGC,D:GDP:mTORC1 [lysosomal membrane] (Drosophila melanogaster)
mTORC1 [cytosol] (Drosophila melanogaster)
mTor [cytosol] (Drosophila melanogaster)
v-ATPase:Ragulator:RRAGA,B:GTP:RRAGC,D:GDP binds mTORC1 (Drosophila melanogaster)
mTORC1 [cytosol] (Drosophila melanogaster)
mTor [cytosol] (Drosophila melanogaster)
v-ATPase:Ragulator:RRAGA,B:GTP:RRAGC,D:GDP:mTORC1 [lysosomal membrane] (Drosophila melanogaster)
mTORC1 [cytosol] (Drosophila melanogaster)
mTor [cytosol] (Drosophila melanogaster)
Gene expression (Transcription) (Drosophila melanogaster)
RNA Polymerase II Transcription (Drosophila melanogaster)
Generic Transcription Pathway (Drosophila melanogaster)
Transcriptional Regulation by TP53 (Drosophila melanogaster)
TP53 Regulates Metabolic Genes (Drosophila melanogaster)
RHEB in mTORC1:RHEB:GTP hydrolyses GTP (Drosophila melanogaster)
Active mTORC1 complex [lysosomal membrane] (Drosophila melanogaster)
mTORC1:Ragulator:RagA,B:GTP:RagC,D:GDP:SLC38A9 [lysosomal membrane] (Drosophila melanogaster)
mTORC1 [cytosol] (Drosophila melanogaster)
mTor [cytosol] (Drosophila melanogaster)
mTORC1:Ragulator:Rag:GNP:RHEB:GDP [lysosomal membrane] (Drosophila melanogaster)
mTORC1:Ragulator:RagA,B:GTP:RagC,D:GDP:SLC38A9 [lysosomal membrane] (Drosophila melanogaster)
mTORC1 [cytosol] (Drosophila melanogaster)
mTor [cytosol] (Drosophila melanogaster)
Immune System (Drosophila melanogaster)
Adaptive Immune System (Drosophila melanogaster)
Regulation of T cell activation by CD28 family (Drosophila melanogaster)
Co-stimulation by CD28 (Drosophila melanogaster)
CD28 dependent PI3K/Akt signaling (Drosophila melanogaster)
TORC2 (mTOR) phosphorylates AKT at S473 (Drosophila melanogaster)
TORC2 complex [cytosol] (Drosophila melanogaster)
mTor [cytosol] (Drosophila melanogaster)
mTor [cytosol] (Drosophila melanogaster)
Signal Transduction (Drosophila melanogaster)
Intracellular signaling by second messengers (Drosophila melanogaster)
PIP3 activates AKT signaling (Drosophila melanogaster)
PTEN Regulation (Drosophila melanogaster)
Regulation of PTEN gene transcription (Drosophila melanogaster)
MAF1 translocates to the nucleus (Drosophila melanogaster)
Active mTORC1 complex [lysosomal membrane] (Drosophila melanogaster)
mTORC1:Ragulator:RagA,B:GTP:RagC,D:GDP:SLC38A9 [lysosomal membrane] (Drosophila melanogaster)
mTORC1 [cytosol] (Drosophila melanogaster)
mTor [cytosol] (Drosophila melanogaster)
mTORC1 phosphorylates MAF1 (Drosophila melanogaster)
Active mTORC1 complex [lysosomal membrane] (Drosophila melanogaster)
mTORC1:Ragulator:RagA,B:GTP:RagC,D:GDP:SLC38A9 [lysosomal membrane] (Drosophila melanogaster)
mTORC1 [cytosol] (Drosophila melanogaster)
mTor [cytosol] (Drosophila melanogaster)
TORC2 (mTOR) phosphorylates AKT at S473 (Drosophila melanogaster)
TORC2 complex [cytosol] (Drosophila melanogaster)
mTor [cytosol] (Drosophila melanogaster)
mTor [cytosol] (Drosophila melanogaster)
MTOR signalling (Drosophila melanogaster)
AKT1S1 (PRAS40) binds mTORC1 (Drosophila melanogaster)
Active mTORC1 complex [lysosomal membrane] (Drosophila melanogaster)
mTORC1:Ragulator:RagA,B:GTP:RagC,D:GDP:SLC38A9 [lysosomal membrane] (Drosophila melanogaster)
mTORC1 [cytosol] (Drosophila melanogaster)
mTor [cytosol] (Drosophila melanogaster)
mTORC1:RHEB:GTP:AKT1S1 [lysosomal membrane] (Drosophila melanogaster)
Active mTORC1 complex [lysosomal membrane] (Drosophila melanogaster)
mTORC1:Ragulator:RagA,B:GTP:RagC,D:GDP:SLC38A9 [lysosomal membrane] (Drosophila melanogaster)
mTORC1 [cytosol] (Drosophila melanogaster)
mTor [cytosol] (Drosophila melanogaster)
Activated Akt1 phosphorylates AKT1S1 (PRAS40) (Drosophila melanogaster)
mTORC1:RHEB:GTP:AKT1S1 [lysosomal membrane] (Drosophila melanogaster)
Active mTORC1 complex [lysosomal membrane] (Drosophila melanogaster)
mTORC1:Ragulator:RagA,B:GTP:RagC,D:GDP:SLC38A9 [lysosomal membrane] (Drosophila melanogaster)
mTORC1 [cytosol] (Drosophila melanogaster)
mTor [cytosol] (Drosophila melanogaster)
mTORC1:RHEB:GTP:p-T246-AKT1S1 [lysosomal membrane] (Drosophila melanogaster)
Active mTORC1 complex [lysosomal membrane] (Drosophila melanogaster)
mTORC1:Ragulator:RagA,B:GTP:RagC,D:GDP:SLC38A9 [lysosomal membrane] (Drosophila melanogaster)
mTORC1 [cytosol] (Drosophila melanogaster)
mTor [cytosol] (Drosophila melanogaster)
Energy dependent regulation of mTOR by LKB1-AMPK (Drosophila melanogaster)
AMPK phosphorylates Raptor in the mTORC1 complex (Drosophila melanogaster)
Active mTORC1 complex [lysosomal membrane] (Drosophila melanogaster)
mTORC1:Ragulator:RagA,B:GTP:RagC,D:GDP:SLC38A9 [lysosomal membrane] (Drosophila melanogaster)
mTORC1 [cytosol] (Drosophila melanogaster)
mTor [cytosol] (Drosophila melanogaster)
mTORC1 with p-S722,S792-RPTOR:Ragulator:Rag:GNP:RHEB:GTP [lysosomal membrane] (Drosophila melanogaster)
mTORC1 with p-RPTOR:Ragulator:Rag:GNP [lysosomal membrane] (Drosophila melanogaster)
mTORC1 with p-S722,S792-RPTOR [cytosol] (Drosophila melanogaster)
mTor [cytosol] (Drosophila melanogaster)
RHEB in mTORC1:RHEB:GTP hydrolyses GTP (Drosophila melanogaster)
Active mTORC1 complex [lysosomal membrane] (Drosophila melanogaster)
mTORC1:Ragulator:RagA,B:GTP:RagC,D:GDP:SLC38A9 [lysosomal membrane] (Drosophila melanogaster)
mTORC1 [cytosol] (Drosophila melanogaster)
mTor [cytosol] (Drosophila melanogaster)
mTORC1:Ragulator:Rag:GNP:RHEB:GDP [lysosomal membrane] (Drosophila melanogaster)
mTORC1:Ragulator:RagA,B:GTP:RagC,D:GDP:SLC38A9 [lysosomal membrane] (Drosophila melanogaster)
mTORC1 [cytosol] (Drosophila melanogaster)
mTor [cytosol] (Drosophila melanogaster)
Formation of active mTORC1 complex (Drosophila melanogaster)
Active mTORC1 complex [lysosomal membrane] (Drosophila melanogaster)
mTORC1:Ragulator:RagA,B:GTP:RagC,D:GDP:SLC38A9 [lysosomal membrane] (Drosophila melanogaster)
mTORC1 [cytosol] (Drosophila melanogaster)
mTor [cytosol] (Drosophila melanogaster)
mTORC1:Ragulator:RagA,B:GTP:RagC,D:GDP:SLC38A9 [lysosomal membrane] (Drosophila melanogaster)
mTORC1 [cytosol] (Drosophila melanogaster)
mTor [cytosol] (Drosophila melanogaster)
Phosphorylated AKT1S1:mTORC1 binds YWHAB (Drosophila melanogaster)
mTORC1:RHEB:GTP:p-T246-AKT1S1 [lysosomal membrane] (Drosophila melanogaster)
Active mTORC1 complex [lysosomal membrane] (Drosophila melanogaster)
mTORC1:Ragulator:RagA,B:GTP:RagC,D:GDP:SLC38A9 [lysosomal membrane] (Drosophila melanogaster)
mTORC1 [cytosol] (Drosophila melanogaster)
mTor [cytosol] (Drosophila melanogaster)
mTORC1:p-T246-AKT1S1:YWHAB [lysosomal membrane] (Drosophila melanogaster)
mTORC1:RHEB:GTP:p-T246-AKT1S1 [lysosomal membrane] (Drosophila melanogaster)
Active mTORC1 complex [lysosomal membrane] (Drosophila melanogaster)
mTORC1:Ragulator:RagA,B:GTP:RagC,D:GDP:SLC38A9 [lysosomal membrane] (Drosophila melanogaster)
mTORC1 [cytosol] (Drosophila melanogaster)
mTor [cytosol] (Drosophila melanogaster)
Ragulator:Rag dimers:SLC38A9 bind mTORC1 (Drosophila melanogaster)
mTORC1 [cytosol] (Drosophila melanogaster)
mTor [cytosol] (Drosophila melanogaster)
mTORC1:Ragulator:RagA,B:GTP:RagC,D:GDP:SLC38A9 [lysosomal membrane] (Drosophila melanogaster)
mTORC1 [cytosol] (Drosophila melanogaster)
mTor [cytosol] (Drosophila melanogaster)
mTORC1 phosphorylates AKT1S1 (Drosophila melanogaster)
mTORC1:RHEB:GTP:p-S183,T246-AKT1S1:YWHAB [lysosomal membrane] (Drosophila melanogaster)
mTORC1:RHEB:GTP:p-S183,T246-AKT1S1 [lysosomal membrane] (Drosophila melanogaster)
Active mTORC1 complex [lysosomal membrane] (Drosophila melanogaster)
mTORC1:Ragulator:RagA,B:GTP:RagC,D:GDP:SLC38A9 [lysosomal membrane] (Drosophila melanogaster)
mTORC1 [cytosol] (Drosophila melanogaster)
mTor [cytosol] (Drosophila melanogaster)
mTORC1:p-T246-AKT1S1:YWHAB [lysosomal membrane] (Drosophila melanogaster)
mTORC1:RHEB:GTP:p-T246-AKT1S1 [lysosomal membrane] (Drosophila melanogaster)
Active mTORC1 complex [lysosomal membrane] (Drosophila melanogaster)
mTORC1:Ragulator:RagA,B:GTP:RagC,D:GDP:SLC38A9 [lysosomal membrane] (Drosophila melanogaster)
mTORC1 [cytosol] (Drosophila melanogaster)
mTor [cytosol] (Drosophila melanogaster)
mTor [cytosol] (Drosophila melanogaster)
mTORC1-mediated signalling (Drosophila melanogaster)
Phosphorylation of 4E-BP1 by activated mTORC1 (Drosophila melanogaster)
Active mTORC1 complex [lysosomal membrane] (Drosophila melanogaster)
mTORC1:Ragulator:RagA,B:GTP:RagC,D:GDP:SLC38A9 [lysosomal membrane] (Drosophila melanogaster)
mTORC1 [cytosol] (Drosophila melanogaster)
mTor [cytosol] (Drosophila melanogaster)
mTORC1:RHEB:GTP:AKT1S1 [lysosomal membrane] (Drosophila melanogaster)
Active mTORC1 complex [lysosomal membrane] (Drosophila melanogaster)
mTORC1:Ragulator:RagA,B:GTP:RagC,D:GDP:SLC38A9 [lysosomal membrane] (Drosophila melanogaster)
mTORC1 [cytosol] (Drosophila melanogaster)
mTor [cytosol] (Drosophila melanogaster)
mTORC1:p-T246-AKT1S1:YWHAB [lysosomal membrane] (Drosophila melanogaster)
mTORC1:RHEB:GTP:p-T246-AKT1S1 [lysosomal membrane] (Drosophila melanogaster)
Active mTORC1 complex [lysosomal membrane] (Drosophila melanogaster)
mTORC1:Ragulator:RagA,B:GTP:RagC,D:GDP:SLC38A9 [lysosomal membrane] (Drosophila melanogaster)
mTORC1 [cytosol] (Drosophila melanogaster)
mTor [cytosol] (Drosophila melanogaster)
mTor [cytosol] (Drosophila melanogaster)
mTORC1 phosphorylation of RPS6KB1 (S6K) (Drosophila melanogaster)
Active mTORC1 complex [lysosomal membrane] (Drosophila melanogaster)
mTORC1:Ragulator:RagA,B:GTP:RagC,D:GDP:SLC38A9 [lysosomal membrane] (Drosophila melanogaster)
mTORC1 [cytosol] (Drosophila melanogaster)
mTor [cytosol] (Drosophila melanogaster)
mTORC1 with p-S722,S792-RPTOR:Ragulator:Rag:GNP:RHEB:GTP [lysosomal membrane] (Drosophila melanogaster)
mTORC1 with p-RPTOR:Ragulator:Rag:GNP [lysosomal membrane] (Drosophila melanogaster)
mTORC1 with p-S722,S792-RPTOR [cytosol] (Drosophila melanogaster)
mTor [cytosol] (Drosophila melanogaster)
mTORC1:p-T246-AKT1S1:YWHAB [lysosomal membrane] (Drosophila melanogaster)
mTORC1:RHEB:GTP:p-T246-AKT1S1 [lysosomal membrane] (Drosophila melanogaster)
Active mTORC1 complex [lysosomal membrane] (Drosophila melanogaster)
mTORC1:Ragulator:RagA,B:GTP:RagC,D:GDP:SLC38A9 [lysosomal membrane] (Drosophila melanogaster)
mTORC1 [cytosol] (Drosophila melanogaster)
mTor [cytosol] (Drosophila melanogaster)
mTor [cytosol] (Drosophila melanogaster)
Signaling by Receptor Tyrosine Kinases (Drosophila melanogaster)
Signaling by VEGF (Drosophila melanogaster)
VEGFA-VEGFR2 Pathway (Drosophila melanogaster)
VEGFR2 mediated vascular permeability (Drosophila melanogaster)
TORC2 (mTOR) phosphorylates AKT at S473 (Drosophila melanogaster)
TORC2 complex [cytosol] (Drosophila melanogaster)
mTor [cytosol] (Drosophila melanogaster)
mTor [cytosol] (Drosophila melanogaster)
External Reference Information
External Reference
UniProt:Q9VK45
Gene Names
mTor
Reference Genes
BioGPS Gene:47396 mTor
ENSEMBL:FBgn0021796
FlyBase:FBgn0021796
KEGG:dme:Dmel_CG5092 mTor
Monarch:47396 mTor
NCBI Gene:47396 mTor
UCSC:Q9VK45 mTor
Reference Transcript
RefSeq:NM_080152.3 mTor
Other Identifiers
141496_at
1641510_at
47396
GO:0001558
GO:0001934
GO:0002376
GO:0003677
GO:0003824
GO:0004672
GO:0004674
GO:0005515
GO:0005524
GO:0005634
GO:0005737
GO:0005829
GO:0006355
GO:0006468
GO:0006914
GO:0007430
GO:0008286
GO:0008340
GO:0008406
GO:0009967
GO:0010507
GO:0012501
GO:0016192
GO:0016236
GO:0016242
GO:0016301
GO:0016310
GO:0016740
GO:0019219
GO:0022414
GO:0030154
GO:0031490
GO:0031670
GO:0031929
GO:0031931
GO:0031932
GO:0032456
GO:0035096
GO:0035171
GO:0035264
GO:0038202
GO:0042221
GO:0043066
GO:0043226
GO:0043621
GO:0044877
GO:0045176
GO:0045727
GO:0045793
GO:0045887
GO:0045945
GO:0046628
GO:0048010
GO:0048142
GO:0048813
GO:0048856
GO:0051128
GO:0051247
GO:0051729
GO:0051897
GO:0090070
GO:0090303
GO:0106310
GO:0140096
GO:1901799
GO:1902669
GO:2000331
GO:2000377
GO:2001023
Participates
as a component of
TORC2 complex [cytosol] (Drosophila melanogaster)
mTORC1 [cytosol] (Drosophila melanogaster)
mTORC1 with p-S722,S792-RPTOR [cytosol] (Drosophila melanogaster)
Other forms of this molecule
mTor [nucleoplasm]
Inferred From
MTOR [cytosol]
(Homo sapiens)
Cross References
RefSeq
NP_524891.1
ENSEMBL
FBtr0080422
,
FBpp0080003
PRO
Q9VK45
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