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phospho-sl [plasma membrane]
Stable Identifier
R-DME-167679
Type
Protein [EntityWithAccessionedSequence]
Species
Drosophila melanogaster
Compartment
plasma membrane
Synonyms
p-4Y-PLCG1, Q9VXH3
Locations in the PathwayBrowser
Expand all
Immune System (Drosophila melanogaster)
Adaptive Immune System (Drosophila melanogaster)
TCR signaling (Drosophila melanogaster)
Generation of second messenger molecules (Drosophila melanogaster)
PLC-gamma1 hydrolyses PIP2 (Drosophila melanogaster)
phospho-sl [plasma membrane] (Drosophila melanogaster)
Translocation of PLC-gamma1 to PIP2 (Drosophila melanogaster)
Activated PLC gamma1 bound to PIP2 [plasma membrane] (Drosophila melanogaster)
phospho-sl [plasma membrane] (Drosophila melanogaster)
Signal Transduction (Drosophila melanogaster)
Signaling by Receptor Tyrosine Kinases (Drosophila melanogaster)
Signaling by EGFR (Drosophila melanogaster)
EGFR interacts with phospholipase C-gamma (Drosophila melanogaster)
Active PLC-gamma1 dissociates from EGFR (Drosophila melanogaster)
EGF-like ligand:p-6Y-EGFR:p-Y472,771,783,1254-PLCG1 [plasma membrane] (Drosophila melanogaster)
phospho-sl [plasma membrane] (Drosophila melanogaster)
phospho-sl [plasma membrane] (Drosophila melanogaster)
EGFR activates PLC-gamma1 by phosphorylation (Drosophila melanogaster)
EGF-like ligand:p-6Y-EGFR:p-Y472,771,783,1254-PLCG1 [plasma membrane] (Drosophila melanogaster)
phospho-sl [plasma membrane] (Drosophila melanogaster)
Signaling by FGFR (Drosophila melanogaster)
Signaling by FGFR1 (Drosophila melanogaster)
Downstream signaling of activated FGFR1 (Drosophila melanogaster)
Phospholipase C-mediated cascade: FGFR1 (Drosophila melanogaster)
Activated FGFR1 phosphorylates PLCG1 (Drosophila melanogaster)
activated FGFR1:p-4Y-PLCG1 [plasma membrane] (Drosophila melanogaster)
phospho-sl [plasma membrane] (Drosophila melanogaster)
p-4Y-PLCG1 dissociates from activated FGFR1 (Drosophila melanogaster)
activated FGFR1:p-4Y-PLCG1 [plasma membrane] (Drosophila melanogaster)
phospho-sl [plasma membrane] (Drosophila melanogaster)
phospho-sl [plasma membrane] (Drosophila melanogaster)
Signaling by FGFR2 (Drosophila melanogaster)
Downstream signaling of activated FGFR2 (Drosophila melanogaster)
Phospholipase C-mediated cascade; FGFR2 (Drosophila melanogaster)
Activated FGFR2 phosphorylates PLCG1 (Drosophila melanogaster)
activated FGFR2:p-4Y-PLCG1 [plasma membrane] (Drosophila melanogaster)
phospho-sl [plasma membrane] (Drosophila melanogaster)
p-4Y-PLCG1 dissociates from activated FGFR2 (Drosophila melanogaster)
activated FGFR2:p-4Y-PLCG1 [plasma membrane] (Drosophila melanogaster)
phospho-sl [plasma membrane] (Drosophila melanogaster)
phospho-sl [plasma membrane] (Drosophila melanogaster)
Signaling by FGFR3 (Drosophila melanogaster)
Downstream signaling of activated FGFR3 (Drosophila melanogaster)
Phospholipase C-mediated cascade; FGFR3 (Drosophila melanogaster)
Activated FGFR3 phosphorylates PLCG1 (Drosophila melanogaster)
activated FGFR3:p-4Y-PLCG1 [plasma membrane] (Drosophila melanogaster)
phospho-sl [plasma membrane] (Drosophila melanogaster)
p-4Y-PLCG1 dissociates from activated FGFR3 (Drosophila melanogaster)
activated FGFR3:p-4Y-PLCG1 [plasma membrane] (Drosophila melanogaster)
phospho-sl [plasma membrane] (Drosophila melanogaster)
phospho-sl [plasma membrane] (Drosophila melanogaster)
Signaling by FGFR4 (Drosophila melanogaster)
Downstream signaling of activated FGFR4 (Drosophila melanogaster)
Phospholipase C-mediated cascade; FGFR4 (Drosophila melanogaster)
Activated FGFR4 phosphorylates PLCG1 (Drosophila melanogaster)
activated FGFR4:p-4Y-PLCG1 [plasma membrane] (Drosophila melanogaster)
phospho-sl [plasma membrane] (Drosophila melanogaster)
p-4Y-PLCG1 dissociates from activated FGFR4 (Drosophila melanogaster)
activated FGFR4:p-4Y-PLCG1 [plasma membrane] (Drosophila melanogaster)
phospho-sl [plasma membrane] (Drosophila melanogaster)
phospho-sl [plasma membrane] (Drosophila melanogaster)
Signaling by PDGF (Drosophila melanogaster)
Downstream signal transduction (Drosophila melanogaster)
Activated PLC gamma dissociates from the PDGF receptor (Drosophila melanogaster)
PDGF:p-PDGFR dimer:p-PLCgamma [plasma membrane] (Drosophila melanogaster)
phospho-sl [plasma membrane] (Drosophila melanogaster)
phospho-sl [plasma membrane] (Drosophila melanogaster)
Phosphorylation of PLCgamma by PDGFR (Drosophila melanogaster)
PDGF:p-PDGFR dimer:p-PLCgamma [plasma membrane] (Drosophila melanogaster)
phospho-sl [plasma membrane] (Drosophila melanogaster)
External Reference Information
External Reference
UniProt:Q9VXH3
Gene Names
sl
Reference Genes
BioGPS Gene:32601 sl
CTD Gene:32601 sl
ENSEMBL:FBgn0003416
Flybase:FBgn0003416
KEGG Gene (Drosophila melanogaster):Dmel_CG4200 sl
Monarch:32601 sl
NCBI Gene:32601 sl
UCSC:Q9VXH3 sl
Reference Transcript
RefSeq:NM_057378.3 sl
Other Identifiers
153466_at
1628815_at
32601
GO:0002009
GO:0002376
GO:0003824
GO:0004435
GO:0005515
GO:0006629
GO:0007165
GO:0007298
GO:0008081
GO:0009395
GO:0009887
GO:0010634
GO:0016042
GO:0016787
GO:0022414
GO:0023052
GO:0030154
GO:0030307
GO:0032868
GO:0035556
GO:0042059
GO:0042690
GO:0045596
GO:0045677
GO:0045873
GO:0048015
GO:0048468
GO:0048513
GO:0048856
GO:0048870
GO:0051209
GO:0055065
GO:0055085
GO:0060429
GO:0070373
GO:0110165
Participates
as an output of
Activated PLC gamma dissociates from the PDGF receptor (Drosophila melanogaster)
p-4Y-PLCG1 dissociates from activated FGFR4 (Drosophila melanogaster)
p-4Y-PLCG1 dissociates from activated FGFR2 (Drosophila melanogaster)
Active PLC-gamma1 dissociates from EGFR (Drosophila melanogaster)
p-4Y-PLCG1 dissociates from activated FGFR1 (Drosophila melanogaster)
p-4Y-PLCG1 dissociates from activated FGFR3 (Drosophila melanogaster)
as a component of
PDGF:p-PDGFR dimer:p-PLCgamma [plasma membrane] (Drosophila melanogaster)
Activated PLC gamma1 bound to PIP2 [plasma membrane] (Drosophila melanogaster)
activated FGFR4:p-4Y-PLCG1 [plasma membrane] (Drosophila melanogaster)
activated FGFR2:p-4Y-PLCG1 [plasma membrane] (Drosophila melanogaster)
EGF-like ligand:p-6Y-EGFR:p-Y472,771,783,1254-PLCG1 [plasma membrane] (Drosophila melanogaster)
activated FGFR1:p-4Y-PLCG1 [plasma membrane] (Drosophila melanogaster)
activated FGFR3:p-4Y-PLCG1 [plasma membrane] (Drosophila melanogaster)
Other forms of this molecule
phospho-sl [cytosol]
phospho-sl [plasma membrane]
phospho-sl [plasma membrane]
phospho-sl [cytosol]
sl [cytosol]
sl [cytosol]
phospho-sl [plasma membrane]
sl [plasma membrane]
sl [plasma membrane]
phospho-sl [plasma membrane]
Inferred From
p-4Y-PLCG1 [plasma membrane]
(Homo sapiens)
Modified Residues
Name
O4'-phospho-L-tyrosine at 472 (in Homo sapiens)
Coordinate
472
PsiMod Name
O4'-phospho-L-tyrosine [MOD:00048]
PsiMod Definition
A protein modification that effectively converts an L-tyrosine residue to O4'-phospho-L-tyrosine.
Name
O4'-phospho-L-tyrosine at 771 (in Homo sapiens)
Coordinate
771
PsiMod Name
O4'-phospho-L-tyrosine [MOD:00048]
PsiMod Definition
A protein modification that effectively converts an L-tyrosine residue to O4'-phospho-L-tyrosine.
Name
O4'-phospho-L-tyrosine at 783 (in Homo sapiens)
Coordinate
783
PsiMod Name
O4'-phospho-L-tyrosine [MOD:00048]
PsiMod Definition
A protein modification that effectively converts an L-tyrosine residue to O4'-phospho-L-tyrosine.
Name
O4'-phospho-L-tyrosine at 1253 (in Homo sapiens)
Coordinate
1253
PsiMod Name
O4'-phospho-L-tyrosine [MOD:00048]
PsiMod Definition
A protein modification that effectively converts an L-tyrosine residue to O4'-phospho-L-tyrosine.
Cross References
RefSeq
NP_476726.2
Flybase
FBgn0003416
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