DPDK1 phosphorylates and activates DS6K

Stable Identifier
R-DME-169827
Type
Reaction [transition]
Species
Drosophila melanogaster
Compartment
ReviewStatus
5/5
Locations in the PathwayBrowser
General
SVG |   | PPTX  | SBGN
Click the image above or here to open this reaction in the Pathway Browser
The layout of this reaction may differ from that in the pathway view due to the constraints in pathway layout
DPDK1 is thought to directly phosphorylate a Threonine residue in the activation loop of the p70 DS6K catalytic domain.
Literature References
PubMed ID Title Journal Year
11752451 PDK1 regulates growth through Akt and S6K in Drosophila.

Rintelen, F, Hafen, E, Stocker, H, Thomas, G

Proc Natl Acad Sci U S A 2001
Participants
Participates
Catalyst Activity

3-phosphoinositide-dependent protein kinase activity of PK61C [cytosol]

Authored
Created
Cite Us!