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TGFBR2 homodimer [plasma membrane]
Stable Identifier
R-DME-170866
Type
Complex
Species
Drosophila melanogaster
Compartment
plasma membrane
Locations in the PathwayBrowser
Expand all
Signal Transduction (Drosophila melanogaster)
Signaling by TGFB family members (Drosophila melanogaster)
Signaling by TGF-beta Receptor Complex (Drosophila melanogaster)
TGF-beta receptor signaling activates SMADs (Drosophila melanogaster)
Activated type I receptor phosphorylates SMAD2/3 directly (Drosophila melanogaster)
TGFB1:p-TGFBR:ZFYVE9:SMAD2/3 [early endosome membrane] (Drosophila melanogaster)
TGFBR2 homodimer [plasma membrane] (Drosophila melanogaster)
TGFB1:p-TGFBR:ZFYVE9:p-2S-SMAD2,3 [early endosome membrane] (Drosophila melanogaster)
TGFBR2 homodimer [plasma membrane] (Drosophila melanogaster)
An anchoring protein, ZFYVE9 (SARA), recruits SMAD2/3 (Drosophila melanogaster)
TGFB1:TGFBR2:p-TGFBR1 [plasma membrane] (Drosophila melanogaster)
TGFBR2 homodimer [plasma membrane] (Drosophila melanogaster)
TGFB1:p-TGFBR:ZFYVE9:SMAD2/3 [early endosome membrane] (Drosophila melanogaster)
TGFBR2 homodimer [plasma membrane] (Drosophila melanogaster)
Dimeric TGF-beta-1 binds to the receptor (Drosophila melanogaster)
Dimeric TGFB1:TGFBR2 homodimer [plasma membrane] (Drosophila melanogaster)
TGFBR2 homodimer [plasma membrane] (Drosophila melanogaster)
Downregulation of TGF-beta receptor signaling (Drosophila melanogaster)
Degradation of TGF-beta receptor complex (Drosophila melanogaster)
TGFB1:TGFBR2:Ub-p-TGFBR1:Ub-SMAD7 [plasma membrane] (Drosophila melanogaster)
TGFB1: p-TGFBR: I-SMAD7 [plasma membrane] (Drosophila melanogaster)
TGFB1:TGFBR2:p-TGFBR1 [plasma membrane] (Drosophila melanogaster)
TGFBR2 homodimer [plasma membrane] (Drosophila melanogaster)
I-SMAD competes with SMAD2/3 for type I receptor (TGFBR1) (Drosophila melanogaster)
TGFB1: p-TGFBR: I-SMAD7 [plasma membrane] (Drosophila melanogaster)
TGFB1:TGFBR2:p-TGFBR1 [plasma membrane] (Drosophila melanogaster)
TGFBR2 homodimer [plasma membrane] (Drosophila melanogaster)
TGFB1:TGFBR2:p-TGFBR1 [plasma membrane] (Drosophila melanogaster)
TGFBR2 homodimer [plasma membrane] (Drosophila melanogaster)
STRAP stabilizes interaction of activated TGF-beta receptor complex with SMAD7 (Drosophila melanogaster)
TGFB1: p-TGFBR: STRAP: SMAD7 [plasma membrane] (Drosophila melanogaster)
TGFB1:p-TGFBR:STRAP [plasma membrane] (Drosophila melanogaster)
TGFB1:TGFBR2:p-TGFBR1 [plasma membrane] (Drosophila melanogaster)
TGFBR2 homodimer [plasma membrane] (Drosophila melanogaster)
TGFB1:p-TGFBR:STRAP [plasma membrane] (Drosophila melanogaster)
TGFB1:TGFBR2:p-TGFBR1 [plasma membrane] (Drosophila melanogaster)
TGFBR2 homodimer [plasma membrane] (Drosophila melanogaster)
Phosphorylated SMAD2/3 dissociates from TGFBR (Drosophila melanogaster)
TGFB1:p-TGFBR:ZFYVE9 [early endosome membrane] (Drosophila melanogaster)
TGFBR2 homodimer [plasma membrane] (Drosophila melanogaster)
TGFB1:p-TGFBR:ZFYVE9:p-2S-SMAD2,3 [early endosome membrane] (Drosophila melanogaster)
TGFBR2 homodimer [plasma membrane] (Drosophila melanogaster)
TGFBR2 phosphorylates TGFBR1 (Drosophila melanogaster)
TGFB1:TGFBR2:TGFBR1 [plasma membrane] (Drosophila melanogaster)
TGFBR2 homodimer [plasma membrane] (Drosophila melanogaster)
TGFB1:TGFBR2:p-TGFBR1 [plasma membrane] (Drosophila melanogaster)
TGFBR2 homodimer [plasma membrane] (Drosophila melanogaster)
TGFBR2 homodimer [plasma membrane] (Drosophila melanogaster)
TGFBR2 recruits TGFBR1 (Drosophila melanogaster)
Dimeric TGFB1:TGFBR2 homodimer [plasma membrane] (Drosophila melanogaster)
TGFBR2 homodimer [plasma membrane] (Drosophila melanogaster)
TGFB1:TGFBR2:TGFBR1 [plasma membrane] (Drosophila melanogaster)
TGFBR2 homodimer [plasma membrane] (Drosophila melanogaster)
TGF-beta receptor signaling in EMT (epithelial to mesenchymal transition) (Drosophila melanogaster)
Disassembly of tight junctions (Drosophila melanogaster)
Tight Junction Complex:TGFB1:TGFBR2:p-TGFBR1:p-PARD6A:Ub-RHOA:SMURF1 [cell junction] (Drosophila melanogaster)
Tight Junction Complex:TGFB1:TGFBR2:p-TGFBR1:p-PARD6A:RHOA:SMURF1 [plasma membrane] (Drosophila melanogaster)
Tight Junction Complex:TGFB1:TGFBR2:p-TGFBR1:p-PARD6A:RHOA [cell junction] (Drosophila melanogaster)
TGFB1:TGFBR2:p-TGFBR1 [plasma membrane] (Drosophila melanogaster)
TGFBR2 homodimer [plasma membrane] (Drosophila melanogaster)
SMURF1 binds phosphorylated PARD6A (Drosophila melanogaster)
Tight Junction Complex:TGFB1:TGFBR2:p-TGFBR1:p-PARD6A:RHOA [cell junction] (Drosophila melanogaster)
TGFB1:TGFBR2:p-TGFBR1 [plasma membrane] (Drosophila melanogaster)
TGFBR2 homodimer [plasma membrane] (Drosophila melanogaster)
Tight Junction Complex:TGFB1:TGFBR2:p-TGFBR1:p-PARD6A:RHOA:SMURF1 [plasma membrane] (Drosophila melanogaster)
Tight Junction Complex:TGFB1:TGFBR2:p-TGFBR1:p-PARD6A:RHOA [cell junction] (Drosophila melanogaster)
TGFB1:TGFBR2:p-TGFBR1 [plasma membrane] (Drosophila melanogaster)
TGFBR2 homodimer [plasma membrane] (Drosophila melanogaster)
SMURF1 ubiquitinates RHOA (Drosophila melanogaster)
Tight Junction Complex:TGFB1:TGFBR2:p-TGFBR1:p-PARD6A:RHOA:SMURF1 [plasma membrane] (Drosophila melanogaster)
Tight Junction Complex:TGFB1:TGFBR2:p-TGFBR1:p-PARD6A:RHOA [cell junction] (Drosophila melanogaster)
TGFB1:TGFBR2:p-TGFBR1 [plasma membrane] (Drosophila melanogaster)
TGFBR2 homodimer [plasma membrane] (Drosophila melanogaster)
Tight Junction Complex:TGFB1:TGFBR2:p-TGFBR1:p-PARD6A:Ub-RHOA:SMURF1 [cell junction] (Drosophila melanogaster)
Tight Junction Complex:TGFB1:TGFBR2:p-TGFBR1:p-PARD6A:RHOA:SMURF1 [plasma membrane] (Drosophila melanogaster)
Tight Junction Complex:TGFB1:TGFBR2:p-TGFBR1:p-PARD6A:RHOA [cell junction] (Drosophila melanogaster)
TGFB1:TGFBR2:p-TGFBR1 [plasma membrane] (Drosophila melanogaster)
TGFBR2 homodimer [plasma membrane] (Drosophila melanogaster)
General
This complex/polymer has been computationally inferred (based on PANTHER) from a complex/polymer involved in an event that has been demonstrated in another species.
Participants
components
x 2
put [plasma membrane]
(Drosophila melanogaster)
Participates
as a component of
Dimeric TGFB1:TGFBR2 homodimer [plasma membrane] (Drosophila melanogaster)
TGFB1:TGFBR2:TGFBR1 [plasma membrane] (Drosophila melanogaster)
TGFB1:TGFBR2:p-TGFBR1 [plasma membrane] (Drosophila melanogaster)
TGFB1:p-TGFBR:ZFYVE9:SMAD2/3 [early endosome membrane] (Drosophila melanogaster)
TGFB1:p-TGFBR:ZFYVE9 [early endosome membrane] (Drosophila melanogaster)
TGFB1:p-TGFBR:ZFYVE9:p-2S-SMAD2,3 [early endosome membrane] (Drosophila melanogaster)
Inferred From
TGFBR2 homodimer [plasma membrane]
(Homo sapiens)
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