Reactome | APC10 [nucleoplasm]

APC10 [nucleoplasm]

Stable Identifier

R-DME-174047

Type

Protein [EntityWithAccessionedSequence]

Species

Drosophila melanogaster

Compartment

nucleoplasm

Synonyms

ANAPC10, Q9V831

Locations in the PathwayBrowser

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Cellular responses to stimuli (Drosophila melanogaster)

- Cellular responses to stress (Drosophila melanogaster)
  - Cellular Senescence (Drosophila melanogaster)
    - Senescence-Associated Secretory Phenotype (SASP) (Drosophila melanogaster)
      - CDKN1A (p21) prevents association of Cyclin A:Cdk2 with Cdh1 (Drosophila melanogaster)
        
        Cdh1:phospho-APC/C complex [nucleoplasm] (Drosophila melanogaster)
        
        phosphorylated anaphase promoting complex (APC/C) [nucleoplasm] (Drosophila melanogaster)
        
        APC10 [nucleoplasm] (Drosophila melanogaster)
        
        Cyclin A:phospho-Cdk(Thr 160):Cdh1:phosho-APC/C complex [nucleoplasm] (Drosophila melanogaster)
        
        Cdh1:phospho-APC/C complex [nucleoplasm] (Drosophila melanogaster)
        
        phosphorylated anaphase promoting complex (APC/C) [nucleoplasm] (Drosophila melanogaster)
        
        APC10 [nucleoplasm] (Drosophila melanogaster)
      - CDKN1A (p21) prevents phosphorylation of Cdh1 by Cyclin A:Cdk2 (Drosophila melanogaster)
        
        Cyclin A:phospho-Cdk(Thr 160):Cdh1:phosho-APC/C complex [nucleoplasm] (Drosophila melanogaster)
        
        Cdh1:phospho-APC/C complex [nucleoplasm] (Drosophila melanogaster)
        
        phosphorylated anaphase promoting complex (APC/C) [nucleoplasm] (Drosophila melanogaster)
        
        APC10 [nucleoplasm] (Drosophila melanogaster)
        
        Cyclin A:phospho-Cdk2(Thr 160):phospho-Cdh1:phospho-APC/C complex [nucleoplasm] (Drosophila melanogaster)
        
        phospho-Cdh1:phospho-APC/C complex [nucleoplasm] (Drosophila melanogaster)
        
        phosphorylated anaphase promoting complex (APC/C) [nucleoplasm] (Drosophila melanogaster)
        
        APC10 [nucleoplasm] (Drosophila melanogaster)
      - Cdh1:APC/C complex binds EHMT1:EHMT2 (Drosophila melanogaster)
        
        Cdh1:phospho-APC/C complex [nucleoplasm] (Drosophila melanogaster)
        
        phosphorylated anaphase promoting complex (APC/C) [nucleoplasm] (Drosophila melanogaster)
        
        APC10 [nucleoplasm] (Drosophila melanogaster)
        
        EHMT1:EHMT2:Cdh1:p-APC/C [nucleoplasm] (Drosophila melanogaster)
        
        Cdh1:phospho-APC/C complex [nucleoplasm] (Drosophila melanogaster)
        
        phosphorylated anaphase promoting complex (APC/C) [nucleoplasm] (Drosophila melanogaster)
        
        APC10 [nucleoplasm] (Drosophila melanogaster)
      - Cdh1:APC/C ubiquitinates EHMT1 and EHMT2 (Drosophila melanogaster)
        
        EHMT1:EHMT2:Cdh1:p-APC/C [nucleoplasm] (Drosophila melanogaster)
        
        Cdh1:phospho-APC/C complex [nucleoplasm] (Drosophila melanogaster)
        
        phosphorylated anaphase promoting complex (APC/C) [nucleoplasm] (Drosophila melanogaster)
        
        APC10 [nucleoplasm] (Drosophila melanogaster)
        
        Ub-EHMT1:Ub-EHMT2:Cdh1:p-APC/C [nucleoplasm] (Drosophila melanogaster)
        
        Cdh1:phospho-APC/C complex [nucleoplasm] (Drosophila melanogaster)
        
        phosphorylated anaphase promoting complex (APC/C) [nucleoplasm] (Drosophila melanogaster)
        
        APC10 [nucleoplasm] (Drosophila melanogaster)

External Reference Information

External Reference

UniProt:Q9V831

Gene Names

APC10

Reference Genes

BioGPS Gene:36975 APC10

ENSEMBL:FBgn0034231

Flybase:FBgn0034231

KEGG Gene (Drosophila melanogaster):Dmel_CG11419 APC10

Monarch:36975 APC10

NCBI Gene:36975 APC10

UCSC:Q9V831 APC10

Reference Transcript

RefSeq:NM_137379.5 APC10

Other Identifiers

142242_at

1628804_at

36975

GO:0000278

GO:0005634

GO:0005680

GO:0007049

GO:0007113

GO:0030154

GO:0030163

GO:0031145

GO:0036211

GO:0043226

GO:0051301

GO:0070979

GO:2000736

Participates

as a component of

phosphorylated anaphase promoting complex (APC/C) [nucleoplasm] (Drosophila melanogaster)

Other forms of this molecule

APC10 [cytosol]

Inferred From

ANAPC10 [nucleoplasm] (Homo sapiens)

Cross References

RefSeq

NP_611223.4

Flybase

FBgn0034231

PRO

Q9V831

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