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phosphorylated anaphase promoting complex (APC/C) [cytosol]
Stable Identifier
R-DME-174191
Type
Complex
Species
Drosophila melanogaster
Compartment
cytosol
Locations in the PathwayBrowser
Expand all
Cell Cycle (Drosophila melanogaster)
Cell Cycle Checkpoints (Drosophila melanogaster)
Mitotic Spindle Checkpoint (Drosophila melanogaster)
Inhibition of the proteolytic activity of APC/C required for the onset of anaphase by mitotic spindle checkpoint components (Drosophila melanogaster)
Inactivation of APC/C via direct inhibition of the APC/C complex (Drosophila melanogaster)
Binding of the MCC complex to the APC/C complex (Drosophila melanogaster)
MCC:APC/C complex [cytosol] (Drosophila melanogaster)
phosphorylated anaphase promoting complex (APC/C) [cytosol] (Drosophila melanogaster)
phosphorylated anaphase promoting complex (APC/C) [cytosol] (Drosophila melanogaster)
Cell Cycle, Mitotic (Drosophila melanogaster)
M Phase (Drosophila melanogaster)
Mitotic Metaphase and Anaphase (Drosophila melanogaster)
Mitotic Anaphase (Drosophila melanogaster)
Separation of Sister Chromatids (Drosophila melanogaster)
Degradation of multiubiquitinated Securin (Drosophila melanogaster)
CDC20:p-APC/C [cytosol] (Drosophila melanogaster)
phosphorylated anaphase promoting complex (APC/C) [cytosol] (Drosophila melanogaster)
CDC20:pAPC/C:K11polyUb-PTTG1 [cytosol] (Drosophila melanogaster)
CDC20:p-APC/C [cytosol] (Drosophila melanogaster)
phosphorylated anaphase promoting complex (APC/C) [cytosol] (Drosophila melanogaster)
Ubiquitination of Securin by phospho-APC/C:Cdc20 complex (Drosophila melanogaster)
CDC20:p-APC/C:PTTG1 [cytosol] (Drosophila melanogaster)
CDC20:p-APC/C [cytosol] (Drosophila melanogaster)
phosphorylated anaphase promoting complex (APC/C) [cytosol] (Drosophila melanogaster)
CDC20:pAPC/C:K11polyUb-PTTG1 [cytosol] (Drosophila melanogaster)
CDC20:p-APC/C [cytosol] (Drosophila melanogaster)
phosphorylated anaphase promoting complex (APC/C) [cytosol] (Drosophila melanogaster)
phosphorylated anaphase promoting complex (APC/C) [cytosol] (Drosophila melanogaster)
Regulation of mitotic cell cycle (Drosophila melanogaster)
APC/C-mediated degradation of cell cycle proteins (Drosophila melanogaster)
APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1 (Drosophila melanogaster)
Association of cell cycle proteins with the APC/C:Cdh1 complex (Drosophila melanogaster)
cell cycle proteins:phospho-APC/C:Cdh1 complex [cytosol] (Drosophila melanogaster)
phospho-APC/C:Cdh1 complex [cytosol] (Drosophila melanogaster)
phosphorylated anaphase promoting complex (APC/C) [cytosol] (Drosophila melanogaster)
phospho-APC/C:Cdh1 complex [cytosol] (Drosophila melanogaster)
phosphorylated anaphase promoting complex (APC/C) [cytosol] (Drosophila melanogaster)
Degradation of multiubiquitinated cell cycle proteins (Drosophila melanogaster)
multiubiquitinated cell cycle protein:APC/C:Cdh1 complex [cytosol] (Drosophila melanogaster)
cell cycle proteins:phospho-APC/C:Cdh1 complex [cytosol] (Drosophila melanogaster)
phospho-APC/C:Cdh1 complex [cytosol] (Drosophila melanogaster)
phosphorylated anaphase promoting complex (APC/C) [cytosol] (Drosophila melanogaster)
phospho-APC/C:Cdh1 complex [cytosol] (Drosophila melanogaster)
phosphorylated anaphase promoting complex (APC/C) [cytosol] (Drosophila melanogaster)
Ubiquitination of cell cycle proteins targeted by the APC/C:Cdh1complex (Drosophila melanogaster)
cell cycle proteins:phospho-APC/C:Cdh1 complex [cytosol] (Drosophila melanogaster)
phospho-APC/C:Cdh1 complex [cytosol] (Drosophila melanogaster)
phosphorylated anaphase promoting complex (APC/C) [cytosol] (Drosophila melanogaster)
multiubiquitinated cell cycle protein:APC/C:Cdh1 complex [cytosol] (Drosophila melanogaster)
cell cycle proteins:phospho-APC/C:Cdh1 complex [cytosol] (Drosophila melanogaster)
phospho-APC/C:Cdh1 complex [cytosol] (Drosophila melanogaster)
phosphorylated anaphase promoting complex (APC/C) [cytosol] (Drosophila melanogaster)
phosphorylated anaphase promoting complex (APC/C) [cytosol] (Drosophila melanogaster)
Activation of APC/C and APC/C:Cdc20 mediated degradation of mitotic proteins (Drosophila melanogaster)
APC/C:Cdc20 mediated degradation of mitotic proteins (Drosophila melanogaster)
APC/C:Cdc20 mediated degradation of Cyclin B (Drosophila melanogaster)
Association of Cyclin B:Cdc2 with Cdc20:APC/C complex (Drosophila melanogaster)
CDC20:p-APC/C [cytosol] (Drosophila melanogaster)
phosphorylated anaphase promoting complex (APC/C) [cytosol] (Drosophila melanogaster)
Cdc20:phospho-APC/C:Cyclin B:Cdc2 complex [cytosol] (Drosophila melanogaster)
CDC20:p-APC/C [cytosol] (Drosophila melanogaster)
phosphorylated anaphase promoting complex (APC/C) [cytosol] (Drosophila melanogaster)
Degradation of multiubiquitinated Cyclin B (Drosophila melanogaster)
CDC20:p-APC/C [cytosol] (Drosophila melanogaster)
phosphorylated anaphase promoting complex (APC/C) [cytosol] (Drosophila melanogaster)
multiubiquitinated Cyclin B:Cdc2:Cdc20:phospho-APC/C complex [cytosol] (Drosophila melanogaster)
Cdc20:phospho-APC/C:Cyclin B:Cdc2 complex [cytosol] (Drosophila melanogaster)
CDC20:p-APC/C [cytosol] (Drosophila melanogaster)
phosphorylated anaphase promoting complex (APC/C) [cytosol] (Drosophila melanogaster)
Ubiquitination of Cyclin B by phospho-APC/C:Cdc20 complex (Drosophila melanogaster)
Cdc20:phospho-APC/C:Cyclin B:Cdc2 complex [cytosol] (Drosophila melanogaster)
CDC20:p-APC/C [cytosol] (Drosophila melanogaster)
phosphorylated anaphase promoting complex (APC/C) [cytosol] (Drosophila melanogaster)
multiubiquitinated Cyclin B:Cdc2:Cdc20:phospho-APC/C complex [cytosol] (Drosophila melanogaster)
Cdc20:phospho-APC/C:Cyclin B:Cdc2 complex [cytosol] (Drosophila melanogaster)
CDC20:p-APC/C [cytosol] (Drosophila melanogaster)
phosphorylated anaphase promoting complex (APC/C) [cytosol] (Drosophila melanogaster)
phosphorylated anaphase promoting complex (APC/C) [cytosol] (Drosophila melanogaster)
APC/C:Cdc20 mediated degradation of Securin (Drosophila melanogaster)
Degradation of multiubiquitinated Securin (Drosophila melanogaster)
CDC20:p-APC/C [cytosol] (Drosophila melanogaster)
phosphorylated anaphase promoting complex (APC/C) [cytosol] (Drosophila melanogaster)
CDC20:pAPC/C:K11polyUb-PTTG1 [cytosol] (Drosophila melanogaster)
CDC20:p-APC/C [cytosol] (Drosophila melanogaster)
phosphorylated anaphase promoting complex (APC/C) [cytosol] (Drosophila melanogaster)
Ubiquitination of Securin by phospho-APC/C:Cdc20 complex (Drosophila melanogaster)
CDC20:p-APC/C:PTTG1 [cytosol] (Drosophila melanogaster)
CDC20:p-APC/C [cytosol] (Drosophila melanogaster)
phosphorylated anaphase promoting complex (APC/C) [cytosol] (Drosophila melanogaster)
CDC20:pAPC/C:K11polyUb-PTTG1 [cytosol] (Drosophila melanogaster)
CDC20:p-APC/C [cytosol] (Drosophila melanogaster)
phosphorylated anaphase promoting complex (APC/C) [cytosol] (Drosophila melanogaster)
phosphorylated anaphase promoting complex (APC/C) [cytosol] (Drosophila melanogaster)
APC:Cdc20 mediated degradation of cell cycle proteins prior to satisfation of the cell cycle checkpoint (Drosophila melanogaster)
APC-Cdc20 mediated degradation of Nek2A (Drosophila melanogaster)
Association of Nek2A with MCC:APC/C (Drosophila melanogaster)
MCC:APC/C complex [cytosol] (Drosophila melanogaster)
phosphorylated anaphase promoting complex (APC/C) [cytosol] (Drosophila melanogaster)
Nek2A:MCC:APC/C complex [cytosol] (Drosophila melanogaster)
MCC:APC/C complex [cytosol] (Drosophila melanogaster)
phosphorylated anaphase promoting complex (APC/C) [cytosol] (Drosophila melanogaster)
Degradation of multiubiquitinated Nek2A (Drosophila melanogaster)
MCC:APC/C complex [cytosol] (Drosophila melanogaster)
phosphorylated anaphase promoting complex (APC/C) [cytosol] (Drosophila melanogaster)
Multiubiquitinated Nek2A [cytosol] (Drosophila melanogaster)
Nek2A:MCC:APC/C complex [cytosol] (Drosophila melanogaster)
MCC:APC/C complex [cytosol] (Drosophila melanogaster)
phosphorylated anaphase promoting complex (APC/C) [cytosol] (Drosophila melanogaster)
Multiubiquitination of Nek2A (Drosophila melanogaster)
Multiubiquitinated Nek2A [cytosol] (Drosophila melanogaster)
Nek2A:MCC:APC/C complex [cytosol] (Drosophila melanogaster)
MCC:APC/C complex [cytosol] (Drosophila melanogaster)
phosphorylated anaphase promoting complex (APC/C) [cytosol] (Drosophila melanogaster)
Nek2A:MCC:APC/C complex [cytosol] (Drosophila melanogaster)
MCC:APC/C complex [cytosol] (Drosophila melanogaster)
phosphorylated anaphase promoting complex (APC/C) [cytosol] (Drosophila melanogaster)
phosphorylated anaphase promoting complex (APC/C) [cytosol] (Drosophila melanogaster)
Cdc20:Phospho-APC/C mediated degradation of Cyclin A (Drosophila melanogaster)
Association of Cyclin A with the APC/C (Drosophila melanogaster)
Cdc2:Cyclin A:MCC:APC/C complex [cytosol] (Drosophila melanogaster)
MCC:APC/C complex [cytosol] (Drosophila melanogaster)
phosphorylated anaphase promoting complex (APC/C) [cytosol] (Drosophila melanogaster)
MCC:APC/C complex [cytosol] (Drosophila melanogaster)
phosphorylated anaphase promoting complex (APC/C) [cytosol] (Drosophila melanogaster)
Degradation multiubiquitinated Cyclin A (Drosophila melanogaster)
MCC:APC/C complex [cytosol] (Drosophila melanogaster)
phosphorylated anaphase promoting complex (APC/C) [cytosol] (Drosophila melanogaster)
multiubiquitinated Cyclin A associated with MCC:APC/C complex [cytosol] (Drosophila melanogaster)
Cdc2:Cyclin A:MCC:APC/C complex [cytosol] (Drosophila melanogaster)
MCC:APC/C complex [cytosol] (Drosophila melanogaster)
phosphorylated anaphase promoting complex (APC/C) [cytosol] (Drosophila melanogaster)
Ubiquitination of Cyclin A by APC/C:Cdc20 complex (Drosophila melanogaster)
Cdc2:Cyclin A:MCC:APC/C complex [cytosol] (Drosophila melanogaster)
MCC:APC/C complex [cytosol] (Drosophila melanogaster)
phosphorylated anaphase promoting complex (APC/C) [cytosol] (Drosophila melanogaster)
MCC:APC/C complex [cytosol] (Drosophila melanogaster)
phosphorylated anaphase promoting complex (APC/C) [cytosol] (Drosophila melanogaster)
multiubiquitinated Cyclin A associated with MCC:APC/C complex [cytosol] (Drosophila melanogaster)
Cdc2:Cyclin A:MCC:APC/C complex [cytosol] (Drosophila melanogaster)
MCC:APC/C complex [cytosol] (Drosophila melanogaster)
phosphorylated anaphase promoting complex (APC/C) [cytosol] (Drosophila melanogaster)
phosphorylated anaphase promoting complex (APC/C) [cytosol] (Drosophila melanogaster)
Activation of APC/C:Cdc20 by dissociation of Cdc20:phospho-APC/C from Cdc20:phospho-APC/C:Mad2:Bub3:BubR1 (Drosophila melanogaster)
CDC20:p-APC/C [cytosol] (Drosophila melanogaster)
phosphorylated anaphase promoting complex (APC/C) [cytosol] (Drosophila melanogaster)
MCC:APC/C complex [cytosol] (Drosophila melanogaster)
phosphorylated anaphase promoting complex (APC/C) [cytosol] (Drosophila melanogaster)
Conversion from APC/C:Cdc20 to APC/C:Cdh1 in late anaphase (Drosophila melanogaster)
Association of Cdh1 with the APC/C (Drosophila melanogaster)
phospho-APC/C:Cdh1 complex [cytosol] (Drosophila melanogaster)
phosphorylated anaphase promoting complex (APC/C) [cytosol] (Drosophila melanogaster)
phosphorylated anaphase promoting complex (APC/C) [cytosol] (Drosophila melanogaster)
Dissociation of Cdc20 from APC/C complex (Drosophila melanogaster)
CDC20:p-APC/C [cytosol] (Drosophila melanogaster)
phosphorylated anaphase promoting complex (APC/C) [cytosol] (Drosophila melanogaster)
phosphorylated anaphase promoting complex (APC/C) [cytosol] (Drosophila melanogaster)
Regulation of APC/C activators between G1/S and early anaphase (Drosophila melanogaster)
Inhibition of the proteolytic activity of APC/C required for the onset of anaphase by mitotic spindle checkpoint components (Drosophila melanogaster)
Inactivation of APC/C via direct inhibition of the APC/C complex (Drosophila melanogaster)
Binding of the MCC complex to the APC/C complex (Drosophila melanogaster)
MCC:APC/C complex [cytosol] (Drosophila melanogaster)
phosphorylated anaphase promoting complex (APC/C) [cytosol] (Drosophila melanogaster)
phosphorylated anaphase promoting complex (APC/C) [cytosol] (Drosophila melanogaster)
S Phase (Drosophila melanogaster)
Synthesis of DNA (Drosophila melanogaster)
Switching of origins to a post-replicative state (Drosophila melanogaster)
CDK-mediated phosphorylation and removal of Cdc6 (Drosophila melanogaster)
Cytoplasmic phosphorylated Cdc6 is ubiquitinated by the anaphase-promoting complex (Drosophila melanogaster)
phospho-APC/C:Cdh1 complex [cytosol] (Drosophila melanogaster)
phosphorylated anaphase promoting complex (APC/C) [cytosol] (Drosophila melanogaster)
DNA Replication (Drosophila melanogaster)
Synthesis of DNA (Drosophila melanogaster)
Switching of origins to a post-replicative state (Drosophila melanogaster)
CDK-mediated phosphorylation and removal of Cdc6 (Drosophila melanogaster)
Cytoplasmic phosphorylated Cdc6 is ubiquitinated by the anaphase-promoting complex (Drosophila melanogaster)
phospho-APC/C:Cdh1 complex [cytosol] (Drosophila melanogaster)
phosphorylated anaphase promoting complex (APC/C) [cytosol] (Drosophila melanogaster)
General
This complex/polymer has been computationally inferred (based on PANTHER) from a complex/polymer involved in an event that has been demonstrated in another species.
Participants
components
APC10 [cytosol]
(Drosophila melanogaster)
APC4 [cytosol]
(Drosophila melanogaster)
APC7 [cytosol]
(Drosophila melanogaster)
Cdc16 [cytosol]
(Drosophila melanogaster)
Cdc23 [cytosol]
(Drosophila melanogaster)
Cdc27 [cytosol]
(Drosophila melanogaster)
eff [cytosol]
(Drosophila melanogaster)
Ghost homologue of ANAPC15 [cytosol]
(Drosophila melanogaster)
Ghost homologue of ANAPC16 [cytosol]
(Drosophila melanogaster)
Ghost homologue of CDC26 [cytosol]
(Drosophila melanogaster)
ida [cytosol]
(Drosophila melanogaster)
lmgA [cytosol]
(Drosophila melanogaster)
mr [cytosol]
(Drosophila melanogaster)
shtd [cytosol]
(Drosophila melanogaster)
Ubc2 [cytosol]
(Drosophila melanogaster)
UBE2S [cytosol]
(Drosophila melanogaster)
vih [cytosol]
(Drosophila melanogaster)
Participates
as an input of
Association of Cdh1 with the APC/C (Drosophila melanogaster)
Binding of the MCC complex to the APC/C complex (Drosophila melanogaster)
as an output of
Dissociation of Cdc20 from APC/C complex (Drosophila melanogaster)
as a component of
CDC20:p-APC/C [cytosol] (Drosophila melanogaster)
phospho-APC/C:Cdh1 complex [cytosol] (Drosophila melanogaster)
MCC:APC/C complex [cytosol] (Drosophila melanogaster)
Inferred From
phosphorylated anaphase promoting complex (APC/C) [cytosol]
(Homo sapiens)
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