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vih [cytosol]
Stable Identifier
R-DME-174244
Type
Protein [EntityWithAccessionedSequence]
Species
Drosophila melanogaster
Compartment
cytosol
Synonyms
UBE2C, Q9VTY6
Locations in the PathwayBrowser
Expand all
Cell Cycle (Drosophila melanogaster)
Cell Cycle Checkpoints (Drosophila melanogaster)
Mitotic Spindle Checkpoint (Drosophila melanogaster)
Inhibition of the proteolytic activity of APC/C required for the onset of anaphase by mitotic spindle checkpoint components (Drosophila melanogaster)
Inactivation of APC/C via direct inhibition of the APC/C complex (Drosophila melanogaster)
Binding of the MCC complex to the APC/C complex (Drosophila melanogaster)
MCC:APC/C complex [cytosol] (Drosophila melanogaster)
phosphorylated anaphase promoting complex (APC/C) [cytosol] (Drosophila melanogaster)
vih [cytosol] (Drosophila melanogaster)
phosphorylated anaphase promoting complex (APC/C) [cytosol] (Drosophila melanogaster)
vih [cytosol] (Drosophila melanogaster)
Cell Cycle, Mitotic (Drosophila melanogaster)
M Phase (Drosophila melanogaster)
Mitotic Metaphase and Anaphase (Drosophila melanogaster)
Mitotic Anaphase (Drosophila melanogaster)
Separation of Sister Chromatids (Drosophila melanogaster)
Degradation of multiubiquitinated Securin (Drosophila melanogaster)
CDC20:p-APC/C [cytosol] (Drosophila melanogaster)
phosphorylated anaphase promoting complex (APC/C) [cytosol] (Drosophila melanogaster)
vih [cytosol] (Drosophila melanogaster)
CDC20:pAPC/C:K11polyUb-PTTG1 [cytosol] (Drosophila melanogaster)
CDC20:p-APC/C [cytosol] (Drosophila melanogaster)
phosphorylated anaphase promoting complex (APC/C) [cytosol] (Drosophila melanogaster)
vih [cytosol] (Drosophila melanogaster)
Ubiquitination of Securin by phospho-APC/C:Cdc20 complex (Drosophila melanogaster)
CDC20:p-APC/C:PTTG1 [cytosol] (Drosophila melanogaster)
CDC20:p-APC/C [cytosol] (Drosophila melanogaster)
phosphorylated anaphase promoting complex (APC/C) [cytosol] (Drosophila melanogaster)
vih [cytosol] (Drosophila melanogaster)
CDC20:pAPC/C:K11polyUb-PTTG1 [cytosol] (Drosophila melanogaster)
CDC20:p-APC/C [cytosol] (Drosophila melanogaster)
phosphorylated anaphase promoting complex (APC/C) [cytosol] (Drosophila melanogaster)
vih [cytosol] (Drosophila melanogaster)
phosphorylated anaphase promoting complex (APC/C) [cytosol] (Drosophila melanogaster)
vih [cytosol] (Drosophila melanogaster)
Regulation of mitotic cell cycle (Drosophila melanogaster)
APC/C-mediated degradation of cell cycle proteins (Drosophila melanogaster)
APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1 (Drosophila melanogaster)
APC/C:Cdh1 polyubiquitinates SKP2 (Drosophila melanogaster)
vih [cytosol] (Drosophila melanogaster)
Association of cell cycle proteins with the APC/C:Cdh1 complex (Drosophila melanogaster)
(APC/C:Cdh1)-targeted cell cycle proteins [cytosol] (Drosophila melanogaster)
vih [cytosol] (Drosophila melanogaster)
cell cycle proteins:phospho-APC/C:Cdh1 complex [cytosol] (Drosophila melanogaster)
(APC/C:Cdh1)-targeted cell cycle proteins [cytosol] (Drosophila melanogaster)
vih [cytosol] (Drosophila melanogaster)
phospho-APC/C:Cdh1 complex [cytosol] (Drosophila melanogaster)
phosphorylated anaphase promoting complex (APC/C) [cytosol] (Drosophila melanogaster)
vih [cytosol] (Drosophila melanogaster)
phospho-APC/C:Cdh1 complex [cytosol] (Drosophila melanogaster)
phosphorylated anaphase promoting complex (APC/C) [cytosol] (Drosophila melanogaster)
vih [cytosol] (Drosophila melanogaster)
Degradation of multiubiquitinated cell cycle proteins (Drosophila melanogaster)
multiubiquitinated cell cycle protein:APC/C:Cdh1 complex [cytosol] (Drosophila melanogaster)
cell cycle proteins:phospho-APC/C:Cdh1 complex [cytosol] (Drosophila melanogaster)
(APC/C:Cdh1)-targeted cell cycle proteins [cytosol] (Drosophila melanogaster)
vih [cytosol] (Drosophila melanogaster)
phospho-APC/C:Cdh1 complex [cytosol] (Drosophila melanogaster)
phosphorylated anaphase promoting complex (APC/C) [cytosol] (Drosophila melanogaster)
vih [cytosol] (Drosophila melanogaster)
phospho-APC/C:Cdh1 complex [cytosol] (Drosophila melanogaster)
phosphorylated anaphase promoting complex (APC/C) [cytosol] (Drosophila melanogaster)
vih [cytosol] (Drosophila melanogaster)
Ubiquitination of cell cycle proteins targeted by the APC/C:Cdh1complex (Drosophila melanogaster)
cell cycle proteins:phospho-APC/C:Cdh1 complex [cytosol] (Drosophila melanogaster)
(APC/C:Cdh1)-targeted cell cycle proteins [cytosol] (Drosophila melanogaster)
vih [cytosol] (Drosophila melanogaster)
phospho-APC/C:Cdh1 complex [cytosol] (Drosophila melanogaster)
phosphorylated anaphase promoting complex (APC/C) [cytosol] (Drosophila melanogaster)
vih [cytosol] (Drosophila melanogaster)
multiubiquitinated cell cycle protein:APC/C:Cdh1 complex [cytosol] (Drosophila melanogaster)
cell cycle proteins:phospho-APC/C:Cdh1 complex [cytosol] (Drosophila melanogaster)
(APC/C:Cdh1)-targeted cell cycle proteins [cytosol] (Drosophila melanogaster)
vih [cytosol] (Drosophila melanogaster)
phospho-APC/C:Cdh1 complex [cytosol] (Drosophila melanogaster)
phosphorylated anaphase promoting complex (APC/C) [cytosol] (Drosophila melanogaster)
vih [cytosol] (Drosophila melanogaster)
phosphorylated anaphase promoting complex (APC/C) [cytosol] (Drosophila melanogaster)
vih [cytosol] (Drosophila melanogaster)
Activation of APC/C and APC/C:Cdc20 mediated degradation of mitotic proteins (Drosophila melanogaster)
APC/C:Cdc20 mediated degradation of mitotic proteins (Drosophila melanogaster)
APC/C:Cdc20 mediated degradation of Cyclin B (Drosophila melanogaster)
Association of Cyclin B:Cdc2 with Cdc20:APC/C complex (Drosophila melanogaster)
CDC20:p-APC/C [cytosol] (Drosophila melanogaster)
phosphorylated anaphase promoting complex (APC/C) [cytosol] (Drosophila melanogaster)
vih [cytosol] (Drosophila melanogaster)
Cdc20:phospho-APC/C:Cyclin B:Cdc2 complex [cytosol] (Drosophila melanogaster)
CDC20:p-APC/C [cytosol] (Drosophila melanogaster)
phosphorylated anaphase promoting complex (APC/C) [cytosol] (Drosophila melanogaster)
vih [cytosol] (Drosophila melanogaster)
Degradation of multiubiquitinated Cyclin B (Drosophila melanogaster)
CDC20:p-APC/C [cytosol] (Drosophila melanogaster)
phosphorylated anaphase promoting complex (APC/C) [cytosol] (Drosophila melanogaster)
vih [cytosol] (Drosophila melanogaster)
multiubiquitinated Cyclin B:Cdc2:Cdc20:phospho-APC/C complex [cytosol] (Drosophila melanogaster)
Cdc20:phospho-APC/C:Cyclin B:Cdc2 complex [cytosol] (Drosophila melanogaster)
CDC20:p-APC/C [cytosol] (Drosophila melanogaster)
phosphorylated anaphase promoting complex (APC/C) [cytosol] (Drosophila melanogaster)
vih [cytosol] (Drosophila melanogaster)
Ubiquitination of Cyclin B by phospho-APC/C:Cdc20 complex (Drosophila melanogaster)
Cdc20:phospho-APC/C:Cyclin B:Cdc2 complex [cytosol] (Drosophila melanogaster)
CDC20:p-APC/C [cytosol] (Drosophila melanogaster)
phosphorylated anaphase promoting complex (APC/C) [cytosol] (Drosophila melanogaster)
vih [cytosol] (Drosophila melanogaster)
multiubiquitinated Cyclin B:Cdc2:Cdc20:phospho-APC/C complex [cytosol] (Drosophila melanogaster)
Cdc20:phospho-APC/C:Cyclin B:Cdc2 complex [cytosol] (Drosophila melanogaster)
CDC20:p-APC/C [cytosol] (Drosophila melanogaster)
phosphorylated anaphase promoting complex (APC/C) [cytosol] (Drosophila melanogaster)
vih [cytosol] (Drosophila melanogaster)
phosphorylated anaphase promoting complex (APC/C) [cytosol] (Drosophila melanogaster)
vih [cytosol] (Drosophila melanogaster)
APC/C:Cdc20 mediated degradation of Securin (Drosophila melanogaster)
Degradation of multiubiquitinated Securin (Drosophila melanogaster)
CDC20:p-APC/C [cytosol] (Drosophila melanogaster)
phosphorylated anaphase promoting complex (APC/C) [cytosol] (Drosophila melanogaster)
vih [cytosol] (Drosophila melanogaster)
CDC20:pAPC/C:K11polyUb-PTTG1 [cytosol] (Drosophila melanogaster)
CDC20:p-APC/C [cytosol] (Drosophila melanogaster)
phosphorylated anaphase promoting complex (APC/C) [cytosol] (Drosophila melanogaster)
vih [cytosol] (Drosophila melanogaster)
Ubiquitination of Securin by phospho-APC/C:Cdc20 complex (Drosophila melanogaster)
CDC20:p-APC/C:PTTG1 [cytosol] (Drosophila melanogaster)
CDC20:p-APC/C [cytosol] (Drosophila melanogaster)
phosphorylated anaphase promoting complex (APC/C) [cytosol] (Drosophila melanogaster)
vih [cytosol] (Drosophila melanogaster)
CDC20:pAPC/C:K11polyUb-PTTG1 [cytosol] (Drosophila melanogaster)
CDC20:p-APC/C [cytosol] (Drosophila melanogaster)
phosphorylated anaphase promoting complex (APC/C) [cytosol] (Drosophila melanogaster)
vih [cytosol] (Drosophila melanogaster)
phosphorylated anaphase promoting complex (APC/C) [cytosol] (Drosophila melanogaster)
vih [cytosol] (Drosophila melanogaster)
APC:Cdc20 mediated degradation of cell cycle proteins prior to satisfation of the cell cycle checkpoint (Drosophila melanogaster)
APC-Cdc20 mediated degradation of Nek2A (Drosophila melanogaster)
Association of Nek2A with MCC:APC/C (Drosophila melanogaster)
MCC:APC/C complex [cytosol] (Drosophila melanogaster)
phosphorylated anaphase promoting complex (APC/C) [cytosol] (Drosophila melanogaster)
vih [cytosol] (Drosophila melanogaster)
Nek2A:MCC:APC/C complex [cytosol] (Drosophila melanogaster)
MCC:APC/C complex [cytosol] (Drosophila melanogaster)
phosphorylated anaphase promoting complex (APC/C) [cytosol] (Drosophila melanogaster)
vih [cytosol] (Drosophila melanogaster)
Degradation of multiubiquitinated Nek2A (Drosophila melanogaster)
MCC:APC/C complex [cytosol] (Drosophila melanogaster)
phosphorylated anaphase promoting complex (APC/C) [cytosol] (Drosophila melanogaster)
vih [cytosol] (Drosophila melanogaster)
Multiubiquitinated Nek2A [cytosol] (Drosophila melanogaster)
Nek2A:MCC:APC/C complex [cytosol] (Drosophila melanogaster)
MCC:APC/C complex [cytosol] (Drosophila melanogaster)
phosphorylated anaphase promoting complex (APC/C) [cytosol] (Drosophila melanogaster)
vih [cytosol] (Drosophila melanogaster)
Multiubiquitination of Nek2A (Drosophila melanogaster)
Multiubiquitinated Nek2A [cytosol] (Drosophila melanogaster)
Nek2A:MCC:APC/C complex [cytosol] (Drosophila melanogaster)
MCC:APC/C complex [cytosol] (Drosophila melanogaster)
phosphorylated anaphase promoting complex (APC/C) [cytosol] (Drosophila melanogaster)
vih [cytosol] (Drosophila melanogaster)
Nek2A:MCC:APC/C complex [cytosol] (Drosophila melanogaster)
MCC:APC/C complex [cytosol] (Drosophila melanogaster)
phosphorylated anaphase promoting complex (APC/C) [cytosol] (Drosophila melanogaster)
vih [cytosol] (Drosophila melanogaster)
phosphorylated anaphase promoting complex (APC/C) [cytosol] (Drosophila melanogaster)
vih [cytosol] (Drosophila melanogaster)
Cdc20:Phospho-APC/C mediated degradation of Cyclin A (Drosophila melanogaster)
Association of Cyclin A with the APC/C (Drosophila melanogaster)
Cdc2:Cyclin A:MCC:APC/C complex [cytosol] (Drosophila melanogaster)
MCC:APC/C complex [cytosol] (Drosophila melanogaster)
phosphorylated anaphase promoting complex (APC/C) [cytosol] (Drosophila melanogaster)
vih [cytosol] (Drosophila melanogaster)
MCC:APC/C complex [cytosol] (Drosophila melanogaster)
phosphorylated anaphase promoting complex (APC/C) [cytosol] (Drosophila melanogaster)
vih [cytosol] (Drosophila melanogaster)
Degradation multiubiquitinated Cyclin A (Drosophila melanogaster)
MCC:APC/C complex [cytosol] (Drosophila melanogaster)
phosphorylated anaphase promoting complex (APC/C) [cytosol] (Drosophila melanogaster)
vih [cytosol] (Drosophila melanogaster)
multiubiquitinated Cyclin A associated with MCC:APC/C complex [cytosol] (Drosophila melanogaster)
Cdc2:Cyclin A:MCC:APC/C complex [cytosol] (Drosophila melanogaster)
MCC:APC/C complex [cytosol] (Drosophila melanogaster)
phosphorylated anaphase promoting complex (APC/C) [cytosol] (Drosophila melanogaster)
vih [cytosol] (Drosophila melanogaster)
Ubiquitination of Cyclin A by APC/C:Cdc20 complex (Drosophila melanogaster)
Cdc2:Cyclin A:MCC:APC/C complex [cytosol] (Drosophila melanogaster)
MCC:APC/C complex [cytosol] (Drosophila melanogaster)
phosphorylated anaphase promoting complex (APC/C) [cytosol] (Drosophila melanogaster)
vih [cytosol] (Drosophila melanogaster)
MCC:APC/C complex [cytosol] (Drosophila melanogaster)
phosphorylated anaphase promoting complex (APC/C) [cytosol] (Drosophila melanogaster)
vih [cytosol] (Drosophila melanogaster)
multiubiquitinated Cyclin A associated with MCC:APC/C complex [cytosol] (Drosophila melanogaster)
Cdc2:Cyclin A:MCC:APC/C complex [cytosol] (Drosophila melanogaster)
MCC:APC/C complex [cytosol] (Drosophila melanogaster)
phosphorylated anaphase promoting complex (APC/C) [cytosol] (Drosophila melanogaster)
vih [cytosol] (Drosophila melanogaster)
phosphorylated anaphase promoting complex (APC/C) [cytosol] (Drosophila melanogaster)
vih [cytosol] (Drosophila melanogaster)
Activation of APC/C:Cdc20 by dissociation of Cdc20:phospho-APC/C from Cdc20:phospho-APC/C:Mad2:Bub3:BubR1 (Drosophila melanogaster)
CDC20:p-APC/C [cytosol] (Drosophila melanogaster)
phosphorylated anaphase promoting complex (APC/C) [cytosol] (Drosophila melanogaster)
vih [cytosol] (Drosophila melanogaster)
MCC:APC/C complex [cytosol] (Drosophila melanogaster)
phosphorylated anaphase promoting complex (APC/C) [cytosol] (Drosophila melanogaster)
vih [cytosol] (Drosophila melanogaster)
Conversion from APC/C:Cdc20 to APC/C:Cdh1 in late anaphase (Drosophila melanogaster)
Association of Cdh1 with the APC/C (Drosophila melanogaster)
phospho-APC/C:Cdh1 complex [cytosol] (Drosophila melanogaster)
phosphorylated anaphase promoting complex (APC/C) [cytosol] (Drosophila melanogaster)
vih [cytosol] (Drosophila melanogaster)
phosphorylated anaphase promoting complex (APC/C) [cytosol] (Drosophila melanogaster)
vih [cytosol] (Drosophila melanogaster)
Dissociation of Cdc20 from APC/C complex (Drosophila melanogaster)
CDC20:p-APC/C [cytosol] (Drosophila melanogaster)
phosphorylated anaphase promoting complex (APC/C) [cytosol] (Drosophila melanogaster)
vih [cytosol] (Drosophila melanogaster)
phosphorylated anaphase promoting complex (APC/C) [cytosol] (Drosophila melanogaster)
vih [cytosol] (Drosophila melanogaster)
Regulation of APC/C activators between G1/S and early anaphase (Drosophila melanogaster)
Inhibition of the proteolytic activity of APC/C required for the onset of anaphase by mitotic spindle checkpoint components (Drosophila melanogaster)
Inactivation of APC/C via direct inhibition of the APC/C complex (Drosophila melanogaster)
Binding of the MCC complex to the APC/C complex (Drosophila melanogaster)
MCC:APC/C complex [cytosol] (Drosophila melanogaster)
phosphorylated anaphase promoting complex (APC/C) [cytosol] (Drosophila melanogaster)
vih [cytosol] (Drosophila melanogaster)
phosphorylated anaphase promoting complex (APC/C) [cytosol] (Drosophila melanogaster)
vih [cytosol] (Drosophila melanogaster)
S Phase (Drosophila melanogaster)
Synthesis of DNA (Drosophila melanogaster)
Switching of origins to a post-replicative state (Drosophila melanogaster)
CDK-mediated phosphorylation and removal of Cdc6 (Drosophila melanogaster)
Cytoplasmic phosphorylated Cdc6 is ubiquitinated by the anaphase-promoting complex (Drosophila melanogaster)
phospho-APC/C:Cdh1 complex [cytosol] (Drosophila melanogaster)
phosphorylated anaphase promoting complex (APC/C) [cytosol] (Drosophila melanogaster)
vih [cytosol] (Drosophila melanogaster)
DNA Replication (Drosophila melanogaster)
Synthesis of DNA (Drosophila melanogaster)
Switching of origins to a post-replicative state (Drosophila melanogaster)
CDK-mediated phosphorylation and removal of Cdc6 (Drosophila melanogaster)
Cytoplasmic phosphorylated Cdc6 is ubiquitinated by the anaphase-promoting complex (Drosophila melanogaster)
phospho-APC/C:Cdh1 complex [cytosol] (Drosophila melanogaster)
phosphorylated anaphase promoting complex (APC/C) [cytosol] (Drosophila melanogaster)
vih [cytosol] (Drosophila melanogaster)
Immune System (Drosophila melanogaster)
Adaptive Immune System (Drosophila melanogaster)
Class I MHC mediated antigen processing & presentation (Drosophila melanogaster)
Antigen processing: Ubiquitination & Proteasome degradation (Drosophila melanogaster)
Interaction of E3 with substrate and E2-Ub complex (Drosophila melanogaster)
Ag-substrate:E3:E2:Ub [cytosol] (Drosophila melanogaster)
Ubiquitin:E2 conjugating enzymes [cytosol] (Drosophila melanogaster)
E2 Ubiquitin-conjugating enzyme [cytosol] (Drosophila melanogaster)
vih [cytosol] (Drosophila melanogaster)
Ubiquitin:E2 conjugating enzymes [cytosol] (Drosophila melanogaster)
E2 Ubiquitin-conjugating enzyme [cytosol] (Drosophila melanogaster)
vih [cytosol] (Drosophila melanogaster)
Polyubiquitination of substrate (Drosophila melanogaster)
E2 Ubiquitin-conjugating enzyme [cytosol] (Drosophila melanogaster)
vih [cytosol] (Drosophila melanogaster)
Ubiquitin:E2 conjugating enzymes [cytosol] (Drosophila melanogaster)
E2 Ubiquitin-conjugating enzyme [cytosol] (Drosophila melanogaster)
vih [cytosol] (Drosophila melanogaster)
Transfer of Ub from E2 to substrate and release of E2 (Drosophila melanogaster)
Ag-substrate:E3:E2:Ub [cytosol] (Drosophila melanogaster)
Ubiquitin:E2 conjugating enzymes [cytosol] (Drosophila melanogaster)
E2 Ubiquitin-conjugating enzyme [cytosol] (Drosophila melanogaster)
vih [cytosol] (Drosophila melanogaster)
E2 Ubiquitin-conjugating enzyme [cytosol] (Drosophila melanogaster)
vih [cytosol] (Drosophila melanogaster)
Transfer of ubiquitin from E1 to E2 (Drosophila melanogaster)
E2 Ubiquitin-conjugating enzyme [cytosol] (Drosophila melanogaster)
vih [cytosol] (Drosophila melanogaster)
Ubiquitin:E2 conjugating enzymes [cytosol] (Drosophila melanogaster)
E2 Ubiquitin-conjugating enzyme [cytosol] (Drosophila melanogaster)
vih [cytosol] (Drosophila melanogaster)
Metabolism of proteins (Drosophila melanogaster)
Post-translational protein modification (Drosophila melanogaster)
Protein ubiquitination (Drosophila melanogaster)
Synthesis of active ubiquitin: roles of E1 and E2 enzymes (Drosophila melanogaster)
UBA1 conjugates ubiquitin to cytosolic E2 enzymes (Drosophila melanogaster)
E2 ubiquitin conjugating enzyme (UBA1 substrate) [cytosol] (Drosophila melanogaster)
vih [cytosol] (Drosophila melanogaster)
External Reference Information
External Reference
UniProt:Q9VTY6
Gene Names
vih
Reference Genes
BioGPS Gene:44118 vih
ENSEMBL:FBgn0264848
Flybase:FBgn0264848
KEGG Gene (Drosophila melanogaster):Dmel_CG10682 vih
Monarch:44118 vih
NCBI Gene:44118 vih
UCSC:Q9VTY6 vih
Reference Transcript
RefSeq:NM_140325.3 vih
Other Identifiers
148664_at
1641150_at
44118
GO:0000151
GO:0000166
GO:0000209
GO:0000278
GO:0003824
GO:0005524
GO:0005634
GO:0005737
GO:0005813
GO:0005815
GO:0005856
GO:0007059
GO:0010458
GO:0016567
GO:0016740
GO:0030071
GO:0030163
GO:0031145
GO:0031616
GO:0036211
GO:0043226
GO:0045732
GO:0045842
GO:0061631
GO:0140014
GO:0140096
Participates
as a member of
E2 ubiquitin conjugating enzyme (UBA1 substrate) [cytosol] (Drosophila melanogaster)
(APC/C:Cdh1)-targeted cell cycle proteins [cytosol] (Drosophila melanogaster)
as a candidate of
E2 Ubiquitin-conjugating enzyme [cytosol] (Drosophila melanogaster)
as a component of
phosphorylated anaphase promoting complex (APC/C) [cytosol] (Drosophila melanogaster)
Other forms of this molecule
vih [cytosol]
vih [nucleoplasm]
vih [nucleoplasm]
Inferred From
UBE2C [cytosol]
(Homo sapiens)
Cross References
RefSeq
NP_648582.1
Flybase
FBgn0264848
IntEnz
2.3.2.24
,
2.3.2.23
PRO
Q9VTY6
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