Reactome | PSMC5 [nucleoplasm]

PSMC5 [nucleoplasm]

Stable Identifier

R-DME-174312

Type

Protein [EntityWithAccessionedSequence]

Species

Drosophila melanogaster

Compartment

nucleoplasm

Synonyms

O18413

Locations in the PathwayBrowser

Expand all

Cellular responses to stimuli (Drosophila melanogaster)

- Cellular responses to stress (Drosophila melanogaster)
  - Cellular response to chemical stress (Drosophila melanogaster)
    - KEAP1-NFE2L2 pathway (Drosophila melanogaster)
      - Nuclear events mediated by NFE2L2 (Drosophila melanogaster)
        
        GSK3B and BTRC:CUL1-mediated-degradation of NFE2L2 (Drosophila melanogaster)
        
        Ub,pS335,S338,T NFE2L2 is degraded (Drosophila melanogaster)
        
        26S proteasome [nucleoplasm] (Drosophila melanogaster)
        
        PSMC5 [nucleoplasm] (Drosophila melanogaster)

Metabolism of proteins (Drosophila melanogaster)

- Post-translational protein modification (Drosophila melanogaster)
  - Deubiquitination (Drosophila melanogaster)
    - Ub-specific processing proteases (Drosophila melanogaster)
      - USP37:RUVLB1:PSMC5 deubiquitinates CCNA1,CCNA2 (Drosophila melanogaster)
        
        USP37:RUVLB1:PSMC5:CCNA1,CCNA2 [nucleoplasm] (Drosophila melanogaster)
        
        USP37:RUVLB1:PSMC5 [nucleoplasm] (Drosophila melanogaster)
        
        PSMC5 [nucleoplasm] (Drosophila melanogaster)
        
        USP37:RUVLB1:PSMC5:PolyUb-CCNA1,PolyUb-CCNA2 [nucleoplasm] (Drosophila melanogaster)
        
        USP37:RUVLB1:PSMC5 [nucleoplasm] (Drosophila melanogaster)
        
        PSMC5 [nucleoplasm] (Drosophila melanogaster)

External Reference Information

External Reference

UniProt:O18413 Rpt6

Gene Names

Rpt6, DUG, Pros45, Ug, CG1489

Chain

chain:1-405

Reference Genes

BioGPS Gene:33105 Rpt6

CTD Gene:33105 Rpt6

KEGG Gene (Drosophila melanogaster):Dmel_CG1489 Rpt6

Monarch:33105 Rpt6

NCBI Gene:33105 Rpt6

Reference Transcript

RefSeq:NM_134603.2 Rpt6

Other Identifiers

154351_at

1639784_at

33105

GO:0000166

GO:0000502

GO:0003824

GO:0005515

GO:0005524

GO:0005634

GO:0005654

GO:0005737

GO:0005829

GO:0005838

GO:0008540

GO:0016787

GO:0016887

GO:0030163

GO:0036402

GO:0043161

GO:0043226

GO:0140657

GO:1901800

Participates

as a component of

Other forms of this molecule

PROS45 [nucleoplasm]

PROS45 [cytosol]

PSMC5 [cytosol]

Inferred From

PSMC5 [nucleoplasm] (Homo sapiens)

Cross References

RefSeq

NP_608447.1

Flybase

FBgn0020369

PRO

O18413

Cite Us!