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mus304 [nucleoplasm]
Stable Identifier
R-DME-176231
Type
Protein [EntityWithAccessionedSequence]
Species
Drosophila melanogaster
Compartment
nucleoplasm
Synonyms
ATRIP, Q9VVN4
Locations in the PathwayBrowser
Expand all
Cell Cycle (Drosophila melanogaster)
Cell Cycle Checkpoints (Drosophila melanogaster)
G2/M Checkpoints (Drosophila melanogaster)
Activation of ATR in response to replication stress (Drosophila melanogaster)
Activation of claspin (Drosophila melanogaster)
ATR:ATRIP [nucleoplasm] (Drosophila melanogaster)
mus304 [nucleoplasm] (Drosophila melanogaster)
Binding of ATR-ATRIP to the RPA-ssDNA complex (Drosophila melanogaster)
ATR:ATRIP [nucleoplasm] (Drosophila melanogaster)
mus304 [nucleoplasm] (Drosophila melanogaster)
ATR:ATRIP:RPA:ssDNA signaling complex [nucleoplasm] (Drosophila melanogaster)
ATR:ATRIP [nucleoplasm] (Drosophila melanogaster)
mus304 [nucleoplasm] (Drosophila melanogaster)
Recruitment and activation of Chk1 (Drosophila melanogaster)
ATR:ATRIP [nucleoplasm] (Drosophila melanogaster)
mus304 [nucleoplasm] (Drosophila melanogaster)
G2/M DNA damage checkpoint (Drosophila melanogaster)
ATR phosphorylates TP53 (Drosophila melanogaster)
ATR:ATRIP [nucleoplasm] (Drosophila melanogaster)
mus304 [nucleoplasm] (Drosophila melanogaster)
ATR:ATRIP:RPA:3' overhanging ssDNA-DSBs:p-MRN:p-S1981,Ac-K3016-ATM:KAT5:BRCA1-C complex:EXO1,DNA2:BLM,WRN:p-S990,Ac-K1249-BRIP1:RAD17:RFC:RAD9:HUS1:RAD1:RHNO1:TOPBP1 [nucleoplasm] (Drosophila melanogaster)
ATR:ATRIP:RPA:3' overhanging ssDNA-DSBs:p-MRN:p-S1981,Ac-K3016-ATM:KAT5:BRCA1-C complex:EXO1,DNA2:BLM,WRN:p-S990,Ac-K1249-BRIP1 [nucleoplasm] (Drosophila melanogaster)
ATR:ATRIP [nucleoplasm] (Drosophila melanogaster)
mus304 [nucleoplasm] (Drosophila melanogaster)
Recruitment and activation of Chk1 (Drosophila melanogaster)
ATR:ATRIP [nucleoplasm] (Drosophila melanogaster)
mus304 [nucleoplasm] (Drosophila melanogaster)
DNA Repair (Drosophila melanogaster)
DNA Double-Strand Break Repair (Drosophila melanogaster)
Homology Directed Repair (Drosophila melanogaster)
HDR through Homologous Recombination (HRR) or Single Strand Annealing (SSA) (Drosophila melanogaster)
Processing of DNA double-strand break ends (Drosophila melanogaster)
ATR phosphorylates RPA2 (Drosophila melanogaster)
ATR:ATRIP [nucleoplasm] (Drosophila melanogaster)
mus304 [nucleoplasm] (Drosophila melanogaster)
ATR:ATRIP:RPA:3' overhanging ssDNA-DSBs:p-MRN:p-S1981,Ac-K3016-ATM:KAT5:BRCA1-C complex:EXO1,DNA2:BLM,WRN:p-S990,Ac-K1249-BRIP1:RAD17:RFC:RAD9:HUS1:RAD1:RHNO1:TOPBP1 [nucleoplasm] (Drosophila melanogaster)
ATR:ATRIP:RPA:3' overhanging ssDNA-DSBs:p-MRN:p-S1981,Ac-K3016-ATM:KAT5:BRCA1-C complex:EXO1,DNA2:BLM,WRN:p-S990,Ac-K1249-BRIP1 [nucleoplasm] (Drosophila melanogaster)
ATR:ATRIP [nucleoplasm] (Drosophila melanogaster)
mus304 [nucleoplasm] (Drosophila melanogaster)
ATR:ATRIP:p-RPA:3' overhanging ssDNA-DSBs:p-MRN:p-S1981,Ac-K3016-ATM:KAT5:BRCA1-C complex:EXO1,DNA2:BLM,WRN:p-S990,Ac-K1249-BRIP1:RAD17:RFC:RAD9:HUS1:RAD1:RHNO1:TOPBP1 [nucleoplasm] (Drosophila melanogaster)
ATR:ATRIP:p-RPA:3' overhanging ssDNA-DSBs:p-MRN:p-S1981,Ac-K3016-ATM:KAT5:BRCA1-C complex [nucleoplasm] (Drosophila melanogaster)
ATR:ATRIP [nucleoplasm] (Drosophila melanogaster)
mus304 [nucleoplasm] (Drosophila melanogaster)
Activation of CHEK1 at resected DNA DSBs (Drosophila melanogaster)
ATR:ATRIP [nucleoplasm] (Drosophila melanogaster)
mus304 [nucleoplasm] (Drosophila melanogaster)
ATR:ATRIP:p-RPA:3' overhanging ssDNA-DSBs:p-MRN:p-S1981,Ac-K3016-ATM:KAT5:BRCA1-C complex:EXO1,DNA2:BLM,WRN:p-S990,Ac-K1249-BRIP1:RAD17:RFC:RAD9:HUS1:RAD1:RHNO1:TOPBP1 [nucleoplasm] (Drosophila melanogaster)
ATR:ATRIP:p-RPA:3' overhanging ssDNA-DSBs:p-MRN:p-S1981,Ac-K3016-ATM:KAT5:BRCA1-C complex [nucleoplasm] (Drosophila melanogaster)
ATR:ATRIP [nucleoplasm] (Drosophila melanogaster)
mus304 [nucleoplasm] (Drosophila melanogaster)
ATR:ATRIP:p-RPA:3' overhanging ssDNA-DSBs:p-MRN:p-S1981,Ac-K3016-ATM:KAT5:BRCA1-C complex:EXO1,DNA2:BLM,WRN:p-S990,Ac-K1249-BRIP1:RAD17:RFC:RAD9:HUS1:RAD1:RHNO1:TOPBP1:TIMELESS:TIPIN:p-T916,S945-CLSPN:CHEK1 [nucleoplasm] (Drosophila melanogaster)
ATR:ATRIP:p-RPA:3' overhanging ssDNA-DSBs:p-MRN:p-S1981,Ac-K3016-ATM:KAT5:BRCA1-C complex [nucleoplasm] (Drosophila melanogaster)
ATR:ATRIP [nucleoplasm] (Drosophila melanogaster)
mus304 [nucleoplasm] (Drosophila melanogaster)
CHEK1 is recruited to resected DNA DSBs (Drosophila melanogaster)
ATR:ATRIP:p-RPA:3' overhanging ssDNA-DSBs:p-MRN:p-S1981,Ac-K3016-ATM:KAT5:BRCA1-C complex:EXO1,DNA2:BLM,WRN:p-S990,Ac-K1249-BRIP1:RAD17:RFC:RAD9:HUS1:RAD1:RHNO1:TOPBP1 [nucleoplasm] (Drosophila melanogaster)
ATR:ATRIP:p-RPA:3' overhanging ssDNA-DSBs:p-MRN:p-S1981,Ac-K3016-ATM:KAT5:BRCA1-C complex [nucleoplasm] (Drosophila melanogaster)
ATR:ATRIP [nucleoplasm] (Drosophila melanogaster)
mus304 [nucleoplasm] (Drosophila melanogaster)
ATR:ATRIP:p-RPA:3' overhanging ssDNA-DSBs:p-MRN:p-S1981,Ac-K3016-ATM:KAT5:BRCA1-C complex:EXO1,DNA2:BLM,WRN:p-S990,Ac-K1249-BRIP1:RAD17:RFC:RAD9:HUS1:RAD1:RHNO1:TOPBP1:TIMELESS:TIPIN:p-T916,S945-CLSPN:CHEK1 [nucleoplasm] (Drosophila melanogaster)
ATR:ATRIP:p-RPA:3' overhanging ssDNA-DSBs:p-MRN:p-S1981,Ac-K3016-ATM:KAT5:BRCA1-C complex [nucleoplasm] (Drosophila melanogaster)
ATR:ATRIP [nucleoplasm] (Drosophila melanogaster)
mus304 [nucleoplasm] (Drosophila melanogaster)
Gene expression (Transcription) (Drosophila melanogaster)
RNA Polymerase II Transcription (Drosophila melanogaster)
Generic Transcription Pathway (Drosophila melanogaster)
Transcriptional Regulation by TP53 (Drosophila melanogaster)
Regulation of TP53 Activity (Drosophila melanogaster)
Regulation of TP53 Activity through Phosphorylation (Drosophila melanogaster)
ATR phosphorylates TP53 (Drosophila melanogaster)
ATR:ATRIP [nucleoplasm] (Drosophila melanogaster)
mus304 [nucleoplasm] (Drosophila melanogaster)
ATR:ATRIP:RPA:3' overhanging ssDNA-DSBs:p-MRN:p-S1981,Ac-K3016-ATM:KAT5:BRCA1-C complex:EXO1,DNA2:BLM,WRN:p-S990,Ac-K1249-BRIP1:RAD17:RFC:RAD9:HUS1:RAD1:RHNO1:TOPBP1 [nucleoplasm] (Drosophila melanogaster)
ATR:ATRIP:RPA:3' overhanging ssDNA-DSBs:p-MRN:p-S1981,Ac-K3016-ATM:KAT5:BRCA1-C complex:EXO1,DNA2:BLM,WRN:p-S990,Ac-K1249-BRIP1 [nucleoplasm] (Drosophila melanogaster)
ATR:ATRIP [nucleoplasm] (Drosophila melanogaster)
mus304 [nucleoplasm] (Drosophila melanogaster)
External Reference Information
External Reference
UniProt:Q9VVN4
Gene Names
mus304
Reference Genes
BioGPS Gene:40003 mus304
ENSEMBL:FBgn0002901
Flybase:FBgn0002901
KEGG Gene (Drosophila melanogaster):Dmel_CG7347 mus304
Monarch:40003 mus304
NCBI Gene:40003 mus304
Reference Transcript
RefSeq:NM_079411.4 mus304
Other Identifiers
155088_at
1638933_at
40003
GO:0000077
GO:0000278
GO:0000723
GO:0005737
GO:0006281
GO:0006310
GO:0006974
GO:0007059
GO:0007131
GO:0007143
GO:0007348
GO:0007444
GO:0009314
GO:0016321
GO:0022414
GO:0023052
GO:0032200
GO:0033314
GO:0048856
GO:0140013
Participates
as a component of
ATR:ATRIP [nucleoplasm] (Drosophila melanogaster)
Inferred From
ATRIP [nucleoplasm]
(Homo sapiens)
Cross References
RefSeq
NP_524135.3
Flybase
FBgn0002901
PRO
Q9VVN4
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