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RHOA [plasma membrane]
Stable Identifier
R-DME-194510
Type
Protein [EntityWithAccessionedSequence]
Species
Drosophila melanogaster
Compartment
plasma membrane
Synonyms
P48148
Locations in the PathwayBrowser
Expand all
Developmental Biology (Drosophila melanogaster)
Nervous system development (Drosophila melanogaster)
Axon guidance (Drosophila melanogaster)
EPH-Ephrin signaling (Drosophila melanogaster)
EPHA-mediated growth cone collapse (Drosophila melanogaster)
NGEF exchanges GTP for GDP on RHOA (Drosophila melanogaster)
RHOA:GDP [plasma membrane] (Drosophila melanogaster)
RHOA [plasma membrane] (Drosophila melanogaster)
RHOA:GTP [plasma membrane] (Drosophila melanogaster)
RHOA [plasma membrane] (Drosophila melanogaster)
EPHB-mediated forward signaling (Drosophila melanogaster)
RHOA:GTP binds ROCK, activating it (Drosophila melanogaster)
RHOA:GTP [plasma membrane] (Drosophila melanogaster)
RHOA [plasma membrane] (Drosophila melanogaster)
RHOA:GTP:ROCK1,ROCK2 [plasma membrane] (Drosophila melanogaster)
RHOA:GTP [plasma membrane] (Drosophila melanogaster)
RHOA [plasma membrane] (Drosophila melanogaster)
p190RhoGEF exchanges GTP for GDP on RHOA, activating it (Drosophila melanogaster)
RHOA:GDP [plasma membrane] (Drosophila melanogaster)
RHOA [plasma membrane] (Drosophila melanogaster)
RHOA:GTP [plasma membrane] (Drosophila melanogaster)
RHOA [plasma membrane] (Drosophila melanogaster)
Semaphorin interactions (Drosophila melanogaster)
Sema4D in semaphorin signaling (Drosophila melanogaster)
Sema4D induced cell migration and growth-cone collapse (Drosophila melanogaster)
Activation of Rho by LARG and PDZ-RhoGEF (Drosophila melanogaster)
RHOA/B/C:GTP [plasma membrane] (Drosophila melanogaster)
RHOA/B/C [plasma membrane] (Drosophila melanogaster)
RHOA [plasma membrane] (Drosophila melanogaster)
RhoA,B,C:GDP [plasma membrane] (Drosophila melanogaster)
RHOA/B/C [plasma membrane] (Drosophila melanogaster)
RHOA [plasma membrane] (Drosophila melanogaster)
ROCK activation by RHO (Drosophila melanogaster)
Activated ROCK:RhoA/B/C:GTP [plasma membrane] (Drosophila melanogaster)
RHOA/B/C:GTP [plasma membrane] (Drosophila melanogaster)
RHOA/B/C [plasma membrane] (Drosophila melanogaster)
RHOA [plasma membrane] (Drosophila melanogaster)
RHOA/B/C:GTP [plasma membrane] (Drosophila melanogaster)
RHOA/B/C [plasma membrane] (Drosophila melanogaster)
RHOA [plasma membrane] (Drosophila melanogaster)
Immune System (Drosophila melanogaster)
Innate Immune System (Drosophila melanogaster)
Neutrophil degranulation (Drosophila melanogaster)
Exocytosis of ficolin-rich granule membrane proteins (Drosophila melanogaster)
Ficolin-rich granule membrane proteins [plasma membrane] (Drosophila melanogaster)
RHOA [plasma membrane] (Drosophila melanogaster)
Exocytosis of secretory granule membrane proteins (Drosophila melanogaster)
Secretory granule membrane proteins [plasma membrane] (Drosophila melanogaster)
RHOA [plasma membrane] (Drosophila melanogaster)
Signal Transduction (Drosophila melanogaster)
Death Receptor Signaling (Drosophila melanogaster)
p75 NTR receptor-mediated signalling (Drosophila melanogaster)
p75NTR regulates axonogenesis (Drosophila melanogaster)
Axonal growth inhibition (RHOA activation) (Drosophila melanogaster)
RhoA is activated by nucleotide exchange and inhibits axonal growth (Drosophila melanogaster)
RHOA:GDP [plasma membrane] (Drosophila melanogaster)
RHOA [plasma membrane] (Drosophila melanogaster)
RHOA:GTP [plasma membrane] (Drosophila melanogaster)
RHOA [plasma membrane] (Drosophila melanogaster)
Signaling by GPCR (Drosophila melanogaster)
GPCR downstream signalling (Drosophila melanogaster)
G alpha (12/13) signalling events (Drosophila melanogaster)
GEFs activate RhoA,B,C (Drosophila melanogaster)
RHOA/B/C:GTP [plasma membrane] (Drosophila melanogaster)
RHOA/B/C [plasma membrane] (Drosophila melanogaster)
RHOA [plasma membrane] (Drosophila melanogaster)
RhoA,B,C:GDP [plasma membrane] (Drosophila melanogaster)
RHOA/B/C [plasma membrane] (Drosophila melanogaster)
RHOA [plasma membrane] (Drosophila melanogaster)
ROCK activation by RHO (Drosophila melanogaster)
Activated ROCK:RhoA/B/C:GTP [plasma membrane] (Drosophila melanogaster)
RHOA/B/C:GTP [plasma membrane] (Drosophila melanogaster)
RHOA/B/C [plasma membrane] (Drosophila melanogaster)
RHOA [plasma membrane] (Drosophila melanogaster)
RHOA/B/C:GTP [plasma membrane] (Drosophila melanogaster)
RHOA/B/C [plasma membrane] (Drosophila melanogaster)
RHOA [plasma membrane] (Drosophila melanogaster)
p115-RhoGEF activation of RHOA (Drosophila melanogaster)
RHOA:GDP [plasma membrane] (Drosophila melanogaster)
RHOA [plasma membrane] (Drosophila melanogaster)
RHOA:GTP [plasma membrane] (Drosophila melanogaster)
RHOA [plasma membrane] (Drosophila melanogaster)
G-protein beta:gamma signalling (Drosophila melanogaster)
G beta:gamma signalling through PI3Kgamma (Drosophila melanogaster)
PIP3 binds to RhoA and activates it (Drosophila melanogaster)
PIP3:RhoA [plasma membrane] (Drosophila melanogaster)
RHOA [plasma membrane] (Drosophila melanogaster)
RHOA [plasma membrane] (Drosophila melanogaster)
Signaling by Non-Receptor Tyrosine Kinases (Drosophila melanogaster)
Signaling by PTK6 (Drosophila melanogaster)
PTK6 Regulates RHO GTPases, RAS GTPase and MAP kinases (Drosophila melanogaster)
ARHGAP35 binds RHOA:GTP (Drosophila melanogaster)
RHOA:GTP [plasma membrane] (Drosophila melanogaster)
RHOA [plasma membrane] (Drosophila melanogaster)
p-Y1105-ARHGAP35:RHOA:GTP [cytosol] (Drosophila melanogaster)
RHOA:GTP [plasma membrane] (Drosophila melanogaster)
RHOA [plasma membrane] (Drosophila melanogaster)
ARHGAP35 stimulates RHOA GTPase activity (Drosophila melanogaster)
RHOA:GDP [plasma membrane] (Drosophila melanogaster)
RHOA [plasma membrane] (Drosophila melanogaster)
p-Y1105-ARHGAP35:RHOA:GTP [cytosol] (Drosophila melanogaster)
RHOA:GTP [plasma membrane] (Drosophila melanogaster)
RHOA [plasma membrane] (Drosophila melanogaster)
Signaling by Receptor Tyrosine Kinases (Drosophila melanogaster)
Signaling by ERBB2 (Drosophila melanogaster)
ERBB2 Regulates Cell Motility (Drosophila melanogaster)
MEMO1 binds RHOA:GTP:DIAPH1 (Drosophila melanogaster)
RHOA:GTP:DIAPH1 [plasma membrane] (Drosophila melanogaster)
RHOA:GTP [plasma membrane] (Drosophila melanogaster)
RHOA [plasma membrane] (Drosophila melanogaster)
p-ERBB2 heterodimers:MEMO1:RHOA:GTP:DIAPH1 [plasma membrane] (Drosophila melanogaster)
RHOA:GTP:DIAPH1 [plasma membrane] (Drosophila melanogaster)
RHOA:GTP [plasma membrane] (Drosophila melanogaster)
RHOA [plasma membrane] (Drosophila melanogaster)
Signaling by NTRKs (Drosophila melanogaster)
Signaling by NTRK1 (TRKA) (Drosophila melanogaster)
PI3K/AKT activation (Drosophila melanogaster)
PIP3 binds to RhoA and activates it (Drosophila melanogaster)
PIP3:RhoA [plasma membrane] (Drosophila melanogaster)
RHOA [plasma membrane] (Drosophila melanogaster)
RHOA [plasma membrane] (Drosophila melanogaster)
Signaling by VEGF (Drosophila melanogaster)
VEGFA-VEGFR2 Pathway (Drosophila melanogaster)
RHOA:GTP:Mg2+ binds ROCK1,ROCK2 (Drosophila melanogaster)
RHOA:GTP [plasma membrane] (Drosophila melanogaster)
RHOA [plasma membrane] (Drosophila melanogaster)
RHOA:GTP:ROCK1,ROCK2 [plasma membrane] (Drosophila melanogaster)
RHOA:GTP [plasma membrane] (Drosophila melanogaster)
RHOA [plasma membrane] (Drosophila melanogaster)
ROCK1,ROCK2 are activated (Drosophila melanogaster)
RHOA:GTP:ROCK1,ROCK2 [plasma membrane] (Drosophila melanogaster)
RHOA:GTP [plasma membrane] (Drosophila melanogaster)
RHOA [plasma membrane] (Drosophila melanogaster)
Signaling by Rho GTPases, Miro GTPases and RHOBTB3 (Drosophila melanogaster)
Signaling by Rho GTPases (Drosophila melanogaster)
RHO GTPase Effectors (Drosophila melanogaster)
RHO GTPases Activate Formins (Drosophila melanogaster)
DIAPH1 binds RHOA:GTP (Drosophila melanogaster)
RHOA:GTP [plasma membrane] (Drosophila melanogaster)
RHOA [plasma membrane] (Drosophila melanogaster)
RHOA:GTP:DIAPH1 [plasma membrane] (Drosophila melanogaster)
RHOA:GTP [plasma membrane] (Drosophila melanogaster)
RHOA [plasma membrane] (Drosophila melanogaster)
RHO GTPases Activate ROCKs (Drosophila melanogaster)
ROCK activation by RHO (Drosophila melanogaster)
Activated ROCK:RhoA/B/C:GTP [plasma membrane] (Drosophila melanogaster)
RHOA/B/C:GTP [plasma membrane] (Drosophila melanogaster)
RHOA/B/C [plasma membrane] (Drosophila melanogaster)
RHOA [plasma membrane] (Drosophila melanogaster)
RHOA/B/C:GTP [plasma membrane] (Drosophila melanogaster)
RHOA/B/C [plasma membrane] (Drosophila melanogaster)
RHOA [plasma membrane] (Drosophila melanogaster)
RHO GTPases Activate Rhotekin and Rhophilins (Drosophila melanogaster)
RHOA:GTP binds RHPN1 or RHPN2 (Drosophila melanogaster)
RHOA:GTP [plasma membrane] (Drosophila melanogaster)
RHOA [plasma membrane] (Drosophila melanogaster)
RHOA:GTP:RHPN1,RHPN2 [plasma membrane] (Drosophila melanogaster)
RHOA:GTP [plasma membrane] (Drosophila melanogaster)
RHOA [plasma membrane] (Drosophila melanogaster)
RHO GTPases activate CIT (Drosophila melanogaster)
Activated CIT binds KIF14 and PRC1 (Drosophila melanogaster)
RHOA,RHOB,RHOC,RAC1:GTP:CIT [plasma membrane] (Drosophila melanogaster)
RHOA,RHOB,RHOC,RAC1:GTP [plasma membrane] (Drosophila melanogaster)
RHOA:GTP [plasma membrane] (Drosophila melanogaster)
RHOA [plasma membrane] (Drosophila melanogaster)
RHOA,RHOB,RHOC,RAC1:GTP:CIT:KIF14:PRC1 [plasma membrane] (Drosophila melanogaster)
RHOA,RHOB,RHOC,RAC1:GTP:CIT [plasma membrane] (Drosophila melanogaster)
RHOA,RHOB,RHOC,RAC1:GTP [plasma membrane] (Drosophila melanogaster)
RHOA:GTP [plasma membrane] (Drosophila melanogaster)
RHOA [plasma membrane] (Drosophila melanogaster)
CIT-3 binds DLG4 (Drosophila melanogaster)
RHOA,RHOB,RHOC,RAC1:GTP:CIT-3 [plasma membrane] (Drosophila melanogaster)
RHOA,RHOB,RHOC,RAC1:GTP [plasma membrane] (Drosophila melanogaster)
RHOA:GTP [plasma membrane] (Drosophila melanogaster)
RHOA [plasma membrane] (Drosophila melanogaster)
RHOA,RHOB,RHOC,RAC1:GTP:CIT-3:DLG4 [plasma membrane] (Drosophila melanogaster)
RHOA,RHOB,RHOC,RAC1:GTP:CIT-3 [plasma membrane] (Drosophila melanogaster)
RHOA,RHOB,RHOC,RAC1:GTP [plasma membrane] (Drosophila melanogaster)
RHOA:GTP [plasma membrane] (Drosophila melanogaster)
RHOA [plasma membrane] (Drosophila melanogaster)
RHO GTPases activate PKNs (Drosophila melanogaster)
PDPK1 phosphorylates PKN1,2,3 (Drosophila melanogaster)
RHOA,RHOB,RHOC,RAC1:GTP [plasma membrane] (Drosophila melanogaster)
RHOA,RHOB,RHOC,RAC1 [plasma membrane] (Drosophila melanogaster)
RHOA [plasma membrane] (Drosophila melanogaster)
RHOA,RHOB,RHOC,RAC1:GTP:PKN1-3:PDPK1:PIP3 [plasma membrane] (Drosophila melanogaster)
RHOA,RHOB,RHOC,RAC1:GTP:PKN1-3 [plasma membrane] (Drosophila melanogaster)
RHOA,RHOB,RHOC,RAC1:GTP [plasma membrane] (Drosophila melanogaster)
RHOA,RHOB,RHOC,RAC1 [plasma membrane] (Drosophila melanogaster)
RHOA [plasma membrane] (Drosophila melanogaster)
RHOA, RHOB, RHOC and RAC1 bind PKN1, PKN2 or PKN3 (Drosophila melanogaster)
RHOA,RHOB,RHOC,RAC1:GTP [plasma membrane] (Drosophila melanogaster)
RHOA,RHOB,RHOC,RAC1 [plasma membrane] (Drosophila melanogaster)
RHOA [plasma membrane] (Drosophila melanogaster)
RHOA,RHOB,RHOC,RAC1:GTP:PKN1-3 [plasma membrane] (Drosophila melanogaster)
RHOA,RHOB,RHOC,RAC1:GTP [plasma membrane] (Drosophila melanogaster)
RHOA,RHOB,RHOC,RAC1 [plasma membrane] (Drosophila melanogaster)
RHOA [plasma membrane] (Drosophila melanogaster)
RHOA,RHOB,RHOC,RAC1:GTP:PKN1,2,3 binds PDPK1:PIP3 (Drosophila melanogaster)
RHOA,RHOB,RHOC,RAC1:GTP:PKN1-3 [plasma membrane] (Drosophila melanogaster)
RHOA,RHOB,RHOC,RAC1:GTP [plasma membrane] (Drosophila melanogaster)
RHOA,RHOB,RHOC,RAC1 [plasma membrane] (Drosophila melanogaster)
RHOA [plasma membrane] (Drosophila melanogaster)
RHOA,RHOB,RHOC,RAC1:GTP:PKN1-3:PDPK1:PIP3 [plasma membrane] (Drosophila melanogaster)
RHOA,RHOB,RHOC,RAC1:GTP:PKN1-3 [plasma membrane] (Drosophila melanogaster)
RHOA,RHOB,RHOC,RAC1:GTP [plasma membrane] (Drosophila melanogaster)
RHOA,RHOB,RHOC,RAC1 [plasma membrane] (Drosophila melanogaster)
RHOA [plasma membrane] (Drosophila melanogaster)
RHO GTPase cycle (Drosophila melanogaster)
RHOA GTPase cycle (Drosophila melanogaster)
GDIs block activation of RHOA (Drosophila melanogaster)
RHOA:GDP [plasma membrane] (Drosophila melanogaster)
RHOA [plasma membrane] (Drosophila melanogaster)
RHOA GAPs stimulate RHOA GTPase activity (Drosophila melanogaster)
RHOA:GDP [plasma membrane] (Drosophila melanogaster)
RHOA [plasma membrane] (Drosophila melanogaster)
RHOA:GTP [plasma membrane] (Drosophila melanogaster)
RHOA [plasma membrane] (Drosophila melanogaster)
RHOA GEFs activate RHOA (Drosophila melanogaster)
RHOA:GDP [plasma membrane] (Drosophila melanogaster)
RHOA [plasma membrane] (Drosophila melanogaster)
RHOA:GTP [plasma membrane] (Drosophila melanogaster)
RHOA [plasma membrane] (Drosophila melanogaster)
RHOA binds effectors at the plasma membrane (Drosophila melanogaster)
RHOA:GTP [plasma membrane] (Drosophila melanogaster)
RHOA [plasma membrane] (Drosophila melanogaster)
RHOA:GTP:cytosolic RHOA effectors [plasma membrane] (Drosophila melanogaster)
RHOA:GTP [plasma membrane] (Drosophila melanogaster)
RHOA [plasma membrane] (Drosophila melanogaster)
RHOA:GTP translocates to the ER membrane (Drosophila melanogaster)
RHOA:GTP [plasma membrane] (Drosophila melanogaster)
RHOA [plasma membrane] (Drosophila melanogaster)
External Reference Information
External Reference
UniProt:P48148 Rho1
Gene Names
Rho1, CG8416
Chain
chain:1-189, propeptide:190-192
Reference Genes
BioGPS Gene:36775 Rho1
KEGG Gene (Drosophila melanogaster):Dmel_CG8416 Rho1
Monarch:36775 Rho1
NCBI Gene:36775 Rho1
UCSC:P48148 Rho1
Reference Transcript
RefSeq:NM_134308.3 Rho1
RefSeq:NM_057750.4 Rho1
RefSeq:NM_166139.3 Rho1
RefSeq:NM_134309.2 Rho1
RefSeq:NM_206128.2 Rho1
RefSeq:NM_206127.2 Rho1
Other Identifiers
152814_at
1625488_s_at
1626808_s_at
36775
GO:0000166
GO:0000278
GO:0000281
GO:0000910
GO:0001745
GO:0002376
GO:0003006
GO:0003383
GO:0003779
GO:0003824
GO:0003924
GO:0005515
GO:0005525
GO:0005737
GO:0005829
GO:0005856
GO:0005886
GO:0005938
GO:0006897
GO:0007010
GO:0007015
GO:0007163
GO:0007165
GO:0007264
GO:0007298
GO:0007349
GO:0007368
GO:0007370
GO:0007374
GO:0007377
GO:0007391
GO:0007395
GO:0007405
GO:0007411
GO:0007422
GO:0007424
GO:0007435
GO:0007480
GO:0007601
GO:0008045
GO:0008092
GO:0008104
GO:0008347
GO:0008360
GO:0009611
GO:0010004
GO:0016020
GO:0016192
GO:0016324
GO:0016328
GO:0016476
GO:0016477
GO:0016787
GO:0019900
GO:0019901
GO:0022412
GO:0022414
GO:0023052
GO:0030036
GO:0030154
GO:0030334
GO:0030589
GO:0030865
GO:0030866
GO:0030950
GO:0031410
GO:0031532
GO:0032456
GO:0032956
GO:0034330
GO:0034334
GO:0035006
GO:0035099
GO:0035149
GO:0035159
GO:0035202
GO:0035277
GO:0035298
GO:0035317
GO:0036211
GO:0042060
GO:0042249
GO:0042995
GO:0043226
GO:0044291
GO:0045179
GO:0045184
GO:0045199
GO:0046663
GO:0048812
GO:0048813
GO:0048856
GO:0048870
GO:0050770
GO:0050877
GO:0050896
GO:0051017
GO:0051489
GO:0051493
GO:0060429
GO:0070252
GO:0070451
GO:0070593
GO:0071896
GO:0071902
GO:0090090
GO:0090251
GO:0090254
GO:0090303
GO:0090688
GO:0098542
GO:0110020
GO:1901739
GO:1902408
GO:1903475
GO:1904059
Participates
as a member of
Ficolin-rich granule membrane proteins [plasma membrane] (Drosophila melanogaster)
Secretory granule membrane proteins [plasma membrane] (Drosophila melanogaster)
RHOA/B/C [plasma membrane] (Drosophila melanogaster)
RHOA,RHOB,RHOC,RAC1 [plasma membrane] (Drosophila melanogaster)
as an input of
PIP3 binds to RhoA and activates it (Drosophila melanogaster)
as a component of
PIP3:RhoA [plasma membrane] (Drosophila melanogaster)
RHOA:GDP [plasma membrane] (Drosophila melanogaster)
RHOA:GTP [plasma membrane] (Drosophila melanogaster)
Other forms of this molecule
RHO1 [cytosol]
RHO1 [plasma membrane]
RHOD [mitochondrial outer membrane]
RHOD [cytosol]
RHOD [plasma membrane]
RHOD [Golgi membrane]
RHOA [ficolin-1-rich granule membrane]
RHOF [plasma membrane]
RHOF [secretory granule membrane]
RHOA [secretory granule membrane]
RHOA [endoplasmic reticulum membrane]
RHOB [cytosol]
RHOD [endosome membrane]
RHOA [cytosol]
RHOB [endosome membrane]
RHOA [cell junction]
RHOB [plasma membrane]
Inferred From
RHOA [plasma membrane]
(Homo sapiens)
Cross References
RefSeq
NP_599136.1
,
NP_725524.1
,
NP_599135.1
,
NP_995849.1
,
NP_995850.1
,
NP_477098.1
Flybase
FBgn0014020
PRO
P48148
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