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p-S33,S37,T41,S45 CTNNB1:p-AXIN:CK1alpha:GSK3B:phospho-ub-APC (20 aa repeat region):PP2A:AMER1 complex [cytosol]
Stable Identifier
R-DME-195297
Type
Complex
Species
Drosophila melanogaster
Compartment
cytosol
Locations in the PathwayBrowser
Expand all
Signal Transduction (Drosophila melanogaster)
Signaling by WNT (Drosophila melanogaster)
Degradation of beta-catenin by the destruction complex (Drosophila melanogaster)
Association of beta-catenin with the RBX1:SCF(beta-TrCP1) ubiquitin ligase complex (Drosophila melanogaster)
RBX1:SKP1:CUL1:beta-TrCP1:phosphorylated beta-catenin complex [cytosol] (Drosophila melanogaster)
p-S33,S37,T41,S45 CTNNB1:p-AXIN:CK1alpha:GSK3B:phospho-ub-APC (20 aa repeat region):PP2A:AMER1 complex [cytosol] (Drosophila melanogaster)
p-S33,S37,T41,S45 CTNNB1:p-AXIN:CK1alpha:GSK3B:phospho-ub-APC (20 aa repeat region):PP2A:AMER1 complex [cytosol] (Drosophila melanogaster)
Degradation of ubiquitinated beta catenin by the proteasome (Drosophila melanogaster)
ubiquitinated phospho-beta-catenin:RBX1:SCF(beta-TrCP1) complex [cytosol] (Drosophila melanogaster)
RBX1:SKP1:CUL1:beta-TrCP1:phosphorylated beta-catenin complex [cytosol] (Drosophila melanogaster)
p-S33,S37,T41,S45 CTNNB1:p-AXIN:CK1alpha:GSK3B:phospho-ub-APC (20 aa repeat region):PP2A:AMER1 complex [cytosol] (Drosophila melanogaster)
Dissociation of beta-catenin from Axin and association of beta catenin with phospho-(20 aa) APC in the detruction complex (Drosophila melanogaster)
p-S33,S37,T41,S45 CTNNB1:p-AXIN:CK1alpha:GSK3B:phospho-ub-APC (20 aa repeat region):PP2A:AMER1 complex [cytosol] (Drosophila melanogaster)
Multi-ubiquitination of phospho-beta-catenin by RBX1:SCF(beta-TrCP1) (Drosophila melanogaster)
RBX1:SKP1:CUL1:beta-TrCP1:phosphorylated beta-catenin complex [cytosol] (Drosophila melanogaster)
p-S33,S37,T41,S45 CTNNB1:p-AXIN:CK1alpha:GSK3B:phospho-ub-APC (20 aa repeat region):PP2A:AMER1 complex [cytosol] (Drosophila melanogaster)
ubiquitinated phospho-beta-catenin:RBX1:SCF(beta-TrCP1) complex [cytosol] (Drosophila melanogaster)
RBX1:SKP1:CUL1:beta-TrCP1:phosphorylated beta-catenin complex [cytosol] (Drosophila melanogaster)
p-S33,S37,T41,S45 CTNNB1:p-AXIN:CK1alpha:GSK3B:phospho-ub-APC (20 aa repeat region):PP2A:AMER1 complex [cytosol] (Drosophila melanogaster)
Phosphorylation of APC component of the destruction complex (Drosophila melanogaster)
p-S33,S37,T41,S45 CTNNB1:p-AXIN:CK1alpha:GSK3B:phospho-ub-APC (20 aa repeat region):PP2A:AMER1 complex [cytosol] (Drosophila melanogaster)
General
This complex/polymer has been computationally inferred (based on PANTHER) from a complex/polymer involved in an event that has been demonstrated in another species.
Participants
components
CSNK1A1 [cytosol]
(Drosophila melanogaster)
Ghost homologue of AMER1 [cytosol]
(Drosophila melanogaster)
Homologues of GSK3B [cytosol]
(Drosophila melanogaster)
Homologues of p-ub-APC [cytosol]
(Drosophila melanogaster)
phospho-arm [cytosol]
(Drosophila melanogaster)
phospho-Axn [cytosol]
(Drosophila melanogaster)
PP2A [cytosol]
(Drosophila melanogaster)
Participates
as an input of
Association of beta-catenin with the RBX1:SCF(beta-TrCP1) ubiquitin ligase complex (Drosophila melanogaster)
Dissociation of beta-catenin from Axin and association of beta catenin with phospho-(20 aa) APC in the detruction complex (Drosophila melanogaster)
as an output of
Dissociation of beta-catenin from Axin and association of beta catenin with phospho-(20 aa) APC in the detruction complex (Drosophila melanogaster)
Phosphorylation of APC component of the destruction complex (Drosophila melanogaster)
as a component of
RBX1:SKP1:CUL1:beta-TrCP1:phosphorylated beta-catenin complex [cytosol] (Drosophila melanogaster)
Inferred From
p-S33,S37,T41,S45 CTNNB1:p-AXIN:CK1alpha:GSK3B:phospho-ub-APC (20 aa repeat region):PP2A:AMER1 complex [cytosol]
(Homo sapiens)
p-S33,S37,T41,S45 CTNNB1:p-AXIN:CK1alpha:GSK3B:phospho-ub-APC (20 aa repeat region):PP2A:AMER1 complex [cytosol]
(Homo sapiens)
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