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phospho-gig [cytosol]
Stable Identifier
R-DME-199484
Type
Protein [EntityWithAccessionedSequence]
Species
Drosophila melanogaster
Compartment
cytosol
Synonyms
p-S939,T1462-TSC2, Q9VW83
Locations in the PathwayBrowser
Expand all
Gene expression (Transcription) (Drosophila melanogaster)
RNA Polymerase II Transcription (Drosophila melanogaster)
Generic Transcription Pathway (Drosophila melanogaster)
Transcriptional Regulation by TP53 (Drosophila melanogaster)
TP53 Regulates Metabolic Genes (Drosophila melanogaster)
AKT phosphorylates TSC2, inhibiting it (Drosophila melanogaster)
phospho-gig [cytosol] (Drosophila melanogaster)
p-S939,T1462-TSC2 binding to 14-3-3 dimer is negatively regulated by DDIT4 (Drosophila melanogaster)
p-S939,T1462-TSC2:14-3-3 dimer [cytosol] (Drosophila melanogaster)
phospho-gig [cytosol] (Drosophila melanogaster)
phospho-gig [cytosol] (Drosophila melanogaster)
Signal Transduction (Drosophila melanogaster)
Intracellular signaling by second messengers (Drosophila melanogaster)
PIP3 activates AKT signaling (Drosophila melanogaster)
AKT phosphorylates targets in the cytosol (Drosophila melanogaster)
AKT phosphorylates TSC2, inhibiting it (Drosophila melanogaster)
phospho-gig [cytosol] (Drosophila melanogaster)
External Reference Information
External Reference
UniProt:Q9VW83
Gene Names
gig
Reference Genes
BioGPS Gene:40201 gig
ENSEMBL:FBgn0005198
Flybase:FBgn0005198
Monarch:40201 gig
NCBI Gene:40201 gig
UCSC:Q9VW83 gig
Reference Transcript
RefSeq:NM_079453.3 gig
Other Identifiers
154762_at
1632822_at
40201
GO:0000003
GO:0001934
GO:0002376
GO:0003674
GO:0005096
GO:0005515
GO:0005575
GO:0005622
GO:0005634
GO:0005737
GO:0005829
GO:0006464
GO:0006914
GO:0006950
GO:0007049
GO:0007165
GO:0007267
GO:0007568
GO:0007584
GO:0008150
GO:0008283
GO:0008285
GO:0008340
GO:0009056
GO:0009968
GO:0010508
GO:0019899
GO:0019900
GO:0019901
GO:0022607
GO:0030154
GO:0030178
GO:0030234
GO:0030308
GO:0030948
GO:0032007
GO:0032991
GO:0033596
GO:0034330
GO:0035069
GO:0040007
GO:0042325
GO:0042592
GO:0042632
GO:0043226
GO:0043547
GO:0045792
GO:0045886
GO:0046621
GO:0046627
GO:0048477
GO:0048542
GO:0048856
GO:0051056
GO:0051726
GO:0051898
GO:0055088
GO:0071456
GO:1902350
GO:1904262
GO:1904504
GO:1904515
GO:2000331
Participant Of
input
p-S939,T1462-TSC2 binding to 14-3-3 dimer is negatively regulated by DDIT4
hasComponent
p-S939,T1462-TSC2:14-3-3 dimer [cytosol]
output
AKT phosphorylates TSC2, inhibiting it
Other forms of this molecule
phospho-gig [cytosol]
gig [cytosol]
phospho-gig [cytosol]
Inferred From
p-S939,T1462-TSC2 [cytosol] (Homo sapiens)
Modified Residues
Name
O-phospho-L-serine at 939 (in Homo sapiens)
Coordinate
939
PsiMod Name
O-phospho-L-serine [MOD:00046]
PsiMod Definition
A protein modification that effectively converts an L-serine residue to O-phospho-L-serine.
Name
O-phospho-L-threonine at 1462 (in Homo sapiens)
Coordinate
1462
PsiMod Name
O-phospho-L-threonine [MOD:00047]
PsiMod Definition
A protein modification that effectively converts an L-threonine residue to O-phospho-L-threonine.
Cross References
RefSeq
NP_524177.1
Flybase
FBgn0005198
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