Toggle navigation
About
What is Reactome ?
News
Team
Scientific Advisory Board
Editorial Calendar
Release Calendar
Statistics
Our Logo
License Agreement
Privacy Notice
Disclaimer
Digital Preservation
Contact us
Content
Table of Contents
DOIs
Data Schema
Reactome Research Spotlight
ORCID Integration Project
COVID-19 Disease Pathways
Docs
Userguide
Pathway Browser
How do I search ?
Details Panel
Analysis Tools
Analysis Data
Analysis Gene Expression
Species Comparison
Tissue Distribution
Diseases
Cytomics
Review Status of Reactome Events
ReactomeFIViz
Developer's Zone
Graph Database
Analysis Service
Content Service
Pathways Overview
Pathway Diagrams
Icon Info
EHLD Specs & Guidelines
Icon Library Guidelines
Data Model
Computationally inferred events
FAQ
Linking to Us
Citing us
Tools
Pathway Browser
Analyse gene list
Analyse gene expression
Species Comparison
Tissue Distribution
Analysis Service
Content Service
ReactomeFIViz
Overlays
DisGeNET
Web
API
Advanced Data Search
Site Search
Community
Icon Library
Outreach
Events
Training
Publications
Partners
Contributors
Papers Citing Us
Resources Guide
Collaboration
Download
About
What is Reactome ?
News
Team
Scientific Advisory Board
Editorial Calendar
Release Calendar
Statistics
Our Logo
License Agreement
Privacy Notice
Disclaimer
Digital Preservation
Contact us
Content
Table of Contents
DOIs
Data Schema
Reactome Research Spotlight
ORCID Integration Project
COVID-19 Disease Pathways
Docs
Userguide
Pathway Browser
How do I search ?
Details Panel
Analysis Tools
Analysis Data
Analysis Gene Expression
Species Comparison
Tissue Distribution
Diseases
Cytomics
Review Status of Reactome Events
ReactomeFIViz
Developer's Zone
Graph Database
Analysis Service
Content Service
Pathways Overview
Pathway Diagrams
Icon Info
EHLD Specs & Guidelines
Icon Library Guidelines
Data Model
Computationally inferred events
FAQ
Linking to Us
Citing us
Tools
Pathway Browser
Analyse gene list
Analyse gene expression
Species Comparison
Tissue Distribution
Analysis Service
Content Service
ReactomeFIViz
Overlays
DisGeNET
Web
API
Advanced Data Search
Site Search
Community
Icon Library
Outreach
Events
Training
Publications
Partners
Contributors
Papers Citing Us
Resources Guide
Collaboration
Download
Search ...
Go!
phospho-PRAS40 [cytosol]
Stable Identifier
R-DME-200163
Type
Protein [EntityWithAccessionedSequence]
Species
Drosophila melanogaster
Compartment
cytosol
Synonyms
p-S183,T246-AKT1S1, Q7JXA2
Locations in the PathwayBrowser
Expand all
Signal Transduction (Drosophila melanogaster)
Intracellular signaling by second messengers (Drosophila melanogaster)
PIP3 activates AKT signaling (Drosophila melanogaster)
AKT phosphorylates targets in the cytosol (Drosophila melanogaster)
AKT phosphorylates AKT1S1 (PRAS40) (Drosophila melanogaster)
phospho-PRAS40 [cytosol] (Drosophila melanogaster)
MTOR signalling (Drosophila melanogaster)
mTORC1 phosphorylates AKT1S1 (Drosophila melanogaster)
mTORC1:RHEB:GTP:p-S183,T246-AKT1S1:YWHAB [lysosomal membrane] (Drosophila melanogaster)
mTORC1:RHEB:GTP:p-S183,T246-AKT1S1 [lysosomal membrane] (Drosophila melanogaster)
phospho-PRAS40 [cytosol] (Drosophila melanogaster)
External Reference Information
External Reference
UniProt:Q7JXA2
Gene Names
PRAS40
Reference Genes
BioGPS Gene:26067067 PRAS40
CTD Gene:26067067 PRAS40
ENSEMBL:FBgn0267824
Flybase:FBgn0267824
KEGG Gene (Drosophila melanogaster):Dmel_CG46146 PRAS40
Monarch:26067067 PRAS40
NCBI Gene:26067067 PRAS40
UCSC:Q7JXA2 PRAS40
Reference Transcript
RefSeq:NM_001316420.1 PRAS40
Other Identifiers
147206_at
1637785_at
26067067
GO:0005737
GO:0005829
GO:0006469
GO:0007219
GO:0023052
GO:0030948
GO:0032007
GO:0036211
GO:0046627
GO:0048011
GO:1904262
Participates
as a component of
mTORC1:RHEB:GTP:p-S183,T246-AKT1S1 [lysosomal membrane] (Drosophila melanogaster)
as an output of
AKT phosphorylates AKT1S1 (PRAS40) (Drosophila melanogaster)
Other forms of this molecule
PRAS40 [nucleoplasm]
phospho-PRAS40 [cytosol]
PRAS40 [cytosol]
Inferred From
p-S183,T246-AKT1S1 [cytosol]
(Homo sapiens)
Modified Residues
Name
O-phospho-L-serine at 183 (in Homo sapiens)
Coordinate
183
PsiMod Name
O-phospho-L-serine [MOD:00046]
PsiMod Definition
A protein modification that effectively converts an L-serine residue to O-phospho-L-serine.
Name
O-phospho-L-threonine at 246 (in Homo sapiens)
Coordinate
246
PsiMod Name
O-phospho-L-threonine [MOD:00047]
PsiMod Definition
A protein modification that effectively converts an L-threonine residue to O-phospho-L-threonine.
Cross References
RefSeq
NP_001303349.1
Flybase
FBgn0267824
© 2024
Reactome
Cite Us!
Cite Us!
Cite Us!
Warning!
Unable to extract citation. Please try again later.
Download As:
BibTeX
RIS
Text