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YWHAB dimer [cytosol]
Stable Identifier
R-DME-2028645
Type
Complex
Species
Drosophila melanogaster
Compartment
cytosol
Locations in the PathwayBrowser
Expand all
Cell Cycle (Drosophila melanogaster)
Cell Cycle Checkpoints (Drosophila melanogaster)
G2/M Checkpoints (Drosophila melanogaster)
G2/M DNA damage checkpoint (Drosophila melanogaster)
Chk1/Chk2(Cds1) mediated inactivation of Cyclin B:Cdk1 complex (Drosophila melanogaster)
Association of p-S216-CDC25C with 14-3-3 proteins (Drosophila melanogaster)
14-3-3 dimer [cytosol] (Drosophila melanogaster)
YWHAB dimer [cytosol] (Drosophila melanogaster)
p-S216-CDC25C:14-3-3 protein complex [cytosol] (Drosophila melanogaster)
14-3-3 dimer [cytosol] (Drosophila melanogaster)
YWHAB dimer [cytosol] (Drosophila melanogaster)
Gene expression (Transcription) (Drosophila melanogaster)
RNA Polymerase II Transcription (Drosophila melanogaster)
Generic Transcription Pathway (Drosophila melanogaster)
FOXO-mediated transcription (Drosophila melanogaster)
Regulation of localization of FOXO transcription factors (Drosophila melanogaster)
14-3-3 proteins bind AKT-phosphorylated FOXO1 (Drosophila melanogaster)
YWHAZ dimer,YWHAQ dimer,YWHAG dimer,YWHAB dimer [cytosol] (Drosophila melanogaster)
YWHAB dimer [cytosol] (Drosophila melanogaster)
p-T24,S256,S319-FOXO1:YWHAZ,YWHAQ,YWHAG,YWHAB [cytosol] (Drosophila melanogaster)
YWHAZ dimer,YWHAQ dimer,YWHAG dimer,YWHAB dimer [cytosol] (Drosophila melanogaster)
YWHAB dimer [cytosol] (Drosophila melanogaster)
Transcriptional Regulation by TP53 (Drosophila melanogaster)
TP53 Regulates Metabolic Genes (Drosophila melanogaster)
DDIT4 binds 14-3-3 dimer (Drosophila melanogaster)
14-3-3 dimer [cytosol] (Drosophila melanogaster)
YWHAB dimer [cytosol] (Drosophila melanogaster)
DDIT4:14-3-3 dimer [cytosol] (Drosophila melanogaster)
14-3-3 dimer [cytosol] (Drosophila melanogaster)
YWHAB dimer [cytosol] (Drosophila melanogaster)
p-S939,T1462-TSC2 binding to 14-3-3 dimer is negatively regulated by DDIT4 (Drosophila melanogaster)
14-3-3 dimer [cytosol] (Drosophila melanogaster)
YWHAB dimer [cytosol] (Drosophila melanogaster)
DDIT4:14-3-3 dimer [cytosol] (Drosophila melanogaster)
14-3-3 dimer [cytosol] (Drosophila melanogaster)
YWHAB dimer [cytosol] (Drosophila melanogaster)
p-S939,T1462-TSC2:14-3-3 dimer [cytosol] (Drosophila melanogaster)
14-3-3 dimer [cytosol] (Drosophila melanogaster)
YWHAB dimer [cytosol] (Drosophila melanogaster)
Signal Transduction (Drosophila melanogaster)
MAPK family signaling cascades (Drosophila melanogaster)
MAPK1/MAPK3 signaling (Drosophila melanogaster)
RAF/MAP kinase cascade (Drosophila melanogaster)
MAP2K and MAPK activation (Drosophila melanogaster)
Dissociation of RAS:RAF complex (Drosophila melanogaster)
activated RAF:scaffold:p-2S MAP2K:p-2T MAPK complex [plasma membrane] (Drosophila melanogaster)
p21 RAS:GTP:activated RAF homo/heterodimer complexes [plasma membrane] (Drosophila melanogaster)
p21 RAS:GTP:'activator' RAFs:YWHAB dimer [plasma membrane] (Drosophila melanogaster)
YWHAB dimer [cytosol] (Drosophila melanogaster)
p21RAS:GTP:activated RAF homo/heterodimers [plasma membrane] (Drosophila melanogaster)
YWHAB dimer [cytosol] (Drosophila melanogaster)
Dual mechanism MAP2K inhibitors bind MAP2Ks (Drosophila melanogaster)
activated RAF:scaffold:MAP2K:MAPK complex [plasma membrane] (Drosophila melanogaster)
p21 RAS:GTP:activated RAF homo/heterodimer complexes [plasma membrane] (Drosophila melanogaster)
p21 RAS:GTP:'activator' RAFs:YWHAB dimer [plasma membrane] (Drosophila melanogaster)
YWHAB dimer [cytosol] (Drosophila melanogaster)
activated RAF:scaffold:MAP2K:MAPK complex:dual mechanism MAP2K inhibitors [plasma membrane] (Drosophila melanogaster)
activated RAF:scaffold:MAP2K:MAPK complex [plasma membrane] (Drosophila melanogaster)
p21 RAS:GTP:activated RAF homo/heterodimer complexes [plasma membrane] (Drosophila melanogaster)
p21 RAS:GTP:'activator' RAFs:YWHAB dimer [plasma membrane] (Drosophila melanogaster)
YWHAB dimer [cytosol] (Drosophila melanogaster)
Dual mechanism MAPK inhibitors bind MAPKs (Drosophila melanogaster)
activated RAF:scaffold:p-2S MAP2K:MAPK complex [plasma membrane] (Drosophila melanogaster)
p21 RAS:GTP:activated RAF homo/heterodimer complexes [plasma membrane] (Drosophila melanogaster)
p21 RAS:GTP:'activator' RAFs:YWHAB dimer [plasma membrane] (Drosophila melanogaster)
YWHAB dimer [cytosol] (Drosophila melanogaster)
activated RAF:scaffold:p-2S MAP2K:MAPK:dual mechanism MAPK inhibitors [plasma membrane] (Drosophila melanogaster)
activated RAF:scaffold:p-2S MAP2K:MAPK complex [plasma membrane] (Drosophila melanogaster)
p21 RAS:GTP:activated RAF homo/heterodimer complexes [plasma membrane] (Drosophila melanogaster)
p21 RAS:GTP:'activator' RAFs:YWHAB dimer [plasma membrane] (Drosophila melanogaster)
YWHAB dimer [cytosol] (Drosophila melanogaster)
MAP2Ks and MAPKs bind to the activated RAF complex (Drosophila melanogaster)
activated RAF:scaffold:MAP2K:MAPK complex [plasma membrane] (Drosophila melanogaster)
p21 RAS:GTP:activated RAF homo/heterodimer complexes [plasma membrane] (Drosophila melanogaster)
p21 RAS:GTP:'activator' RAFs:YWHAB dimer [plasma membrane] (Drosophila melanogaster)
YWHAB dimer [cytosol] (Drosophila melanogaster)
p21 RAS:GTP:activated RAF homo/heterodimer complexes [plasma membrane] (Drosophila melanogaster)
p21 RAS:GTP:'activator' RAFs:YWHAB dimer [plasma membrane] (Drosophila melanogaster)
YWHAB dimer [cytosol] (Drosophila melanogaster)
p21 RAS:GTP:activated RAF1 homo/heterodimer:PEBP1 [plasma membrane] (Drosophila melanogaster)
p21RAS:GTP:activated RAF1 homo/heterodimer [plasma membrane] (Drosophila melanogaster)
YWHAB dimer [cytosol] (Drosophila melanogaster)
MAP2Ks phosphorylate MAPKs (Drosophila melanogaster)
activated RAF:scaffold:MAP2K:MAPK complex:dual mechanism MAP2K inhibitors [plasma membrane] (Drosophila melanogaster)
activated RAF:scaffold:MAP2K:MAPK complex [plasma membrane] (Drosophila melanogaster)
p21 RAS:GTP:activated RAF homo/heterodimer complexes [plasma membrane] (Drosophila melanogaster)
p21 RAS:GTP:'activator' RAFs:YWHAB dimer [plasma membrane] (Drosophila melanogaster)
YWHAB dimer [cytosol] (Drosophila melanogaster)
activated RAF:scaffold:p-2S MAP2K:MAPK:single mechanism MAP2K inhibitors [plasma membrane] (Drosophila melanogaster)
activated RAF:scaffold:p-2S MAP2K:MAPK complex [plasma membrane] (Drosophila melanogaster)
p21 RAS:GTP:activated RAF homo/heterodimer complexes [plasma membrane] (Drosophila melanogaster)
p21 RAS:GTP:'activator' RAFs:YWHAB dimer [plasma membrane] (Drosophila melanogaster)
YWHAB dimer [cytosol] (Drosophila melanogaster)
activated RAF:scaffold:p-2S MAP2K:MAPK complex [plasma membrane] (Drosophila melanogaster)
p21 RAS:GTP:activated RAF homo/heterodimer complexes [plasma membrane] (Drosophila melanogaster)
p21 RAS:GTP:'activator' RAFs:YWHAB dimer [plasma membrane] (Drosophila melanogaster)
YWHAB dimer [cytosol] (Drosophila melanogaster)
activated RAF:scaffold:p-2S MAP2K:MAPK:dual mechanism MAPK inhibitors [plasma membrane] (Drosophila melanogaster)
activated RAF:scaffold:p-2S MAP2K:MAPK complex [plasma membrane] (Drosophila melanogaster)
p21 RAS:GTP:activated RAF homo/heterodimer complexes [plasma membrane] (Drosophila melanogaster)
p21 RAS:GTP:'activator' RAFs:YWHAB dimer [plasma membrane] (Drosophila melanogaster)
YWHAB dimer [cytosol] (Drosophila melanogaster)
activated RAF:scaffold:p-2S MAP2K:p-2T MAPK complex [plasma membrane] (Drosophila melanogaster)
p21 RAS:GTP:activated RAF homo/heterodimer complexes [plasma membrane] (Drosophila melanogaster)
p21 RAS:GTP:'activator' RAFs:YWHAB dimer [plasma membrane] (Drosophila melanogaster)
YWHAB dimer [cytosol] (Drosophila melanogaster)
RAF phosphorylates MAP2K dimer (Drosophila melanogaster)
activated RAF:scaffold:MAP2K:MAPK complex [plasma membrane] (Drosophila melanogaster)
p21 RAS:GTP:activated RAF homo/heterodimer complexes [plasma membrane] (Drosophila melanogaster)
p21 RAS:GTP:'activator' RAFs:YWHAB dimer [plasma membrane] (Drosophila melanogaster)
YWHAB dimer [cytosol] (Drosophila melanogaster)
activated RAF:scaffold:MAP2K:MAPK complex:dual mechanism MAP2K inhibitors [plasma membrane] (Drosophila melanogaster)
activated RAF:scaffold:MAP2K:MAPK complex [plasma membrane] (Drosophila melanogaster)
p21 RAS:GTP:activated RAF homo/heterodimer complexes [plasma membrane] (Drosophila melanogaster)
p21 RAS:GTP:'activator' RAFs:YWHAB dimer [plasma membrane] (Drosophila melanogaster)
YWHAB dimer [cytosol] (Drosophila melanogaster)
activated RAF:scaffold:p-2S MAP2K:MAPK complex [plasma membrane] (Drosophila melanogaster)
p21 RAS:GTP:activated RAF homo/heterodimer complexes [plasma membrane] (Drosophila melanogaster)
p21 RAS:GTP:'activator' RAFs:YWHAB dimer [plasma membrane] (Drosophila melanogaster)
YWHAB dimer [cytosol] (Drosophila melanogaster)
p21RAS:GTP:homo/heterodimerized RAF complex:RAF dimer inhibitors [plasma membrane] (Drosophila melanogaster)
p21 RAS:GTP:homo/heterodimerized RAF complex [plasma membrane] (Drosophila melanogaster)
p21 RAS:GTP:'activator' RAF:YWHAB dimer [plasma membrane] (Drosophila melanogaster)
'activator' RAF:YWHAB dimer [cytosol] (Drosophila melanogaster)
YWHAB dimer [cytosol] (Drosophila melanogaster)
Single mechanism MAP2K inhibitors bind phosphorylated MAP2Ks (Drosophila melanogaster)
activated RAF:scaffold:p-2S MAP2K:MAPK:single mechanism MAP2K inhibitors [plasma membrane] (Drosophila melanogaster)
activated RAF:scaffold:p-2S MAP2K:MAPK complex [plasma membrane] (Drosophila melanogaster)
p21 RAS:GTP:activated RAF homo/heterodimer complexes [plasma membrane] (Drosophila melanogaster)
p21 RAS:GTP:'activator' RAFs:YWHAB dimer [plasma membrane] (Drosophila melanogaster)
YWHAB dimer [cytosol] (Drosophila melanogaster)
activated RAF:scaffold:p-2S MAP2K:MAPK complex [plasma membrane] (Drosophila melanogaster)
p21 RAS:GTP:activated RAF homo/heterodimer complexes [plasma membrane] (Drosophila melanogaster)
p21 RAS:GTP:'activator' RAFs:YWHAB dimer [plasma membrane] (Drosophila melanogaster)
YWHAB dimer [cytosol] (Drosophila melanogaster)
Single mechanism MAPK inhibitors bind phosphorylated MAPK (Drosophila melanogaster)
activated RAF:scaffold:p-2S MAP2K:p-2T MAPK complex [plasma membrane] (Drosophila melanogaster)
p21 RAS:GTP:activated RAF homo/heterodimer complexes [plasma membrane] (Drosophila melanogaster)
p21 RAS:GTP:'activator' RAFs:YWHAB dimer [plasma membrane] (Drosophila melanogaster)
YWHAB dimer [cytosol] (Drosophila melanogaster)
activated RAF:scaffold:p-2S MAP2K:p-2T MAPK:single mechanism MAPK inhibitors [plasma membrane] (Drosophila melanogaster)
activated RAF:scaffold:p-2S MAP2K:p-2T MAPK complex [plasma membrane] (Drosophila melanogaster)
p21 RAS:GTP:activated RAF homo/heterodimer complexes [plasma membrane] (Drosophila melanogaster)
p21 RAS:GTP:'activator' RAFs:YWHAB dimer [plasma membrane] (Drosophila melanogaster)
YWHAB dimer [cytosol] (Drosophila melanogaster)
Negative regulation of MAPK pathway (Drosophila melanogaster)
PEBP1 binds activated RAF1 (Drosophila melanogaster)
p21 RAS:GTP:activated RAF1 homo/heterodimer:PEBP1 [plasma membrane] (Drosophila melanogaster)
p21RAS:GTP:activated RAF1 homo/heterodimer [plasma membrane] (Drosophila melanogaster)
YWHAB dimer [cytosol] (Drosophila melanogaster)
p21RAS:GTP:activated RAF1 homo/heterodimer [plasma membrane] (Drosophila melanogaster)
YWHAB dimer [cytosol] (Drosophila melanogaster)
PP2A dephosphorylates RAF1 (Drosophila melanogaster)
p21RAS:GTP:dephosphorylated RAF1 homo/heterodimer [plasma membrane] (Drosophila melanogaster)
YWHAB dimer [cytosol] (Drosophila melanogaster)
p21RAS:GTP:p-S621 RAF1 homo/heterodimer [plasma membrane] (Drosophila melanogaster)
YWHAB dimer [cytosol] (Drosophila melanogaster)
PP5 dephosphorylates RAF1 S338 (Drosophila melanogaster)
p21RAS:GTP:activated RAF1 homo/heterodimer [plasma membrane] (Drosophila melanogaster)
YWHAB dimer [cytosol] (Drosophila melanogaster)
p21RAS:GTP:dephosphorylated RAF1 homo/heterodimer [plasma membrane] (Drosophila melanogaster)
YWHAB dimer [cytosol] (Drosophila melanogaster)
RAF activation (Drosophila melanogaster)
"Activator" RAF:YWHAB dimer binds RAS:GTP (Drosophila melanogaster)
'activator' RAF:YWHAB dimer [cytosol] (Drosophila melanogaster)
YWHAB dimer [cytosol] (Drosophila melanogaster)
p21 RAS:GTP:'activator' RAF:YWHAB dimer [plasma membrane] (Drosophila melanogaster)
'activator' RAF:YWHAB dimer [cytosol] (Drosophila melanogaster)
YWHAB dimer [cytosol] (Drosophila melanogaster)
Inactive RAFs bind YWHAB (Drosophila melanogaster)
YWHAB dimer [cytosol] (Drosophila melanogaster)
inactive RAFs:YWHAB dimer [cytosol] (Drosophila melanogaster)
YWHAB dimer [cytosol] (Drosophila melanogaster)
PP2A dephosphorylates KSR1 (Drosophila melanogaster)
p-S311 KSR1:MARK3:YWHAB dimer [plasma membrane] (Drosophila melanogaster)
YWHAB dimer [cytosol] (Drosophila melanogaster)
p-S311,S406 KSR1:MARK3:YWHAB dimer [cytosol] (Drosophila melanogaster)
YWHAB dimer [cytosol] (Drosophila melanogaster)
PP2A dephosphorylates inactive RAFs (Drosophila melanogaster)
dephosphorylated inactive RAFS:YWHAB dimer [cytosol] (Drosophila melanogaster)
YWHAB dimer [cytosol] (Drosophila melanogaster)
inactive RAFs:YWHAB dimer [cytosol] (Drosophila melanogaster)
YWHAB dimer [cytosol] (Drosophila melanogaster)
Phosphorylation of RAF (Drosophila melanogaster)
p21 RAS:GTP:activated RAF homo/heterodimer complexes [plasma membrane] (Drosophila melanogaster)
p21 RAS:GTP:'activator' RAFs:YWHAB dimer [plasma membrane] (Drosophila melanogaster)
YWHAB dimer [cytosol] (Drosophila melanogaster)
p21 RAS:GTP:homo/heterodimerized RAF complex [plasma membrane] (Drosophila melanogaster)
p21 RAS:GTP:'activator' RAF:YWHAB dimer [plasma membrane] (Drosophila melanogaster)
'activator' RAF:YWHAB dimer [cytosol] (Drosophila melanogaster)
YWHAB dimer [cytosol] (Drosophila melanogaster)
RAS:GTP:'activator' RAF homo/heterodimerizes with other RAF monomers (Drosophila melanogaster)
p21 RAS:GTP:'activator' RAF:YWHAB dimer [plasma membrane] (Drosophila melanogaster)
'activator' RAF:YWHAB dimer [cytosol] (Drosophila melanogaster)
YWHAB dimer [cytosol] (Drosophila melanogaster)
p21 RAS:GTP:homo/heterodimerized RAF complex [plasma membrane] (Drosophila melanogaster)
p21 RAS:GTP:'activator' RAF:YWHAB dimer [plasma membrane] (Drosophila melanogaster)
'activator' RAF:YWHAB dimer [cytosol] (Drosophila melanogaster)
YWHAB dimer [cytosol] (Drosophila melanogaster)
Raf dimer inhibitors bind RAF heterodimers (Drosophila melanogaster)
p21 RAS:GTP:homo/heterodimerized RAF complex [plasma membrane] (Drosophila melanogaster)
p21 RAS:GTP:'activator' RAF:YWHAB dimer [plasma membrane] (Drosophila melanogaster)
'activator' RAF:YWHAB dimer [cytosol] (Drosophila melanogaster)
YWHAB dimer [cytosol] (Drosophila melanogaster)
p21RAS:GTP:homo/heterodimerized RAF complex:RAF dimer inhibitors [plasma membrane] (Drosophila melanogaster)
p21 RAS:GTP:homo/heterodimerized RAF complex [plasma membrane] (Drosophila melanogaster)
p21 RAS:GTP:'activator' RAF:YWHAB dimer [plasma membrane] (Drosophila melanogaster)
'activator' RAF:YWHAB dimer [cytosol] (Drosophila melanogaster)
YWHAB dimer [cytosol] (Drosophila melanogaster)
YWHAB dimer dissociates from KSR1:MARK3 (Drosophila melanogaster)
YWHAB dimer [cytosol] (Drosophila melanogaster)
p-S311 KSR1:MARK3:YWHAB dimer [plasma membrane] (Drosophila melanogaster)
YWHAB dimer [cytosol] (Drosophila melanogaster)
YWHAB dimer dissociates from dephosphorylated RAF (Drosophila melanogaster)
YWHAB dimer [cytosol] (Drosophila melanogaster)
dephosphorylated inactive RAFS:YWHAB dimer [cytosol] (Drosophila melanogaster)
YWHAB dimer [cytosol] (Drosophila melanogaster)
p-S311,S406 KSR1:MARK3 binds YWHAB dimer (Drosophila melanogaster)
YWHAB dimer [cytosol] (Drosophila melanogaster)
p-S311,S406 KSR1:MARK3:YWHAB dimer [cytosol] (Drosophila melanogaster)
YWHAB dimer [cytosol] (Drosophila melanogaster)
Signaling by Rho GTPases, Miro GTPases and RHOBTB3 (Drosophila melanogaster)
Signaling by Rho GTPases (Drosophila melanogaster)
RHO GTPase Effectors (Drosophila melanogaster)
RHO GTPases activate PKNs (Drosophila melanogaster)
Association of p-S216-CDC25C with 14-3-3 proteins (Drosophila melanogaster)
14-3-3 dimer [cytosol] (Drosophila melanogaster)
YWHAB dimer [cytosol] (Drosophila melanogaster)
p-S216-CDC25C:14-3-3 protein complex [cytosol] (Drosophila melanogaster)
14-3-3 dimer [cytosol] (Drosophila melanogaster)
YWHAB dimer [cytosol] (Drosophila melanogaster)
General
This complex/polymer has been computationally inferred (based on PANTHER) from a complex/polymer involved in an event that has been demonstrated in another species.
Participants
components
x 2
14-3-3zeta [cytosol]
(Drosophila melanogaster)
Participates
as a member of
YWHAZ dimer,YWHAQ dimer,YWHAG dimer,YWHAB dimer [cytosol] (Drosophila melanogaster)
14-3-3 dimer [cytosol] (Drosophila melanogaster)
as an output of
YWHAB dimer dissociates from dephosphorylated RAF (Drosophila melanogaster)
YWHAB dimer dissociates from KSR1:MARK3 (Drosophila melanogaster)
as a component of
dephosphorylated inactive RAFS:YWHAB dimer [cytosol] (Drosophila melanogaster)
inactive RAFs:YWHAB dimer [cytosol] (Drosophila melanogaster)
p21RAS:GTP:p-S621 RAF1 homo/heterodimer [plasma membrane] (Drosophila melanogaster)
p21RAS:GTP:dephosphorylated RAF1 homo/heterodimer [plasma membrane] (Drosophila melanogaster)
p-S311,S406 KSR1:MARK3:YWHAB dimer [cytosol] (Drosophila melanogaster)
p-S311 KSR1:MARK3:YWHAB dimer [plasma membrane] (Drosophila melanogaster)
p21RAS:GTP:activated RAF1 homo/heterodimer [plasma membrane] (Drosophila melanogaster)
'activator' RAF:YWHAB dimer [cytosol] (Drosophila melanogaster)
p21RAS:GTP:activated RAF homo/heterodimers [plasma membrane] (Drosophila melanogaster)
p21 RAS:GTP:'activator' RAFs:YWHAB dimer [plasma membrane] (Drosophila melanogaster)
as an input of
Inactive RAFs bind YWHAB (Drosophila melanogaster)
p-S311,S406 KSR1:MARK3 binds YWHAB dimer (Drosophila melanogaster)
Inferred From
YWHAB dimer [cytosol]
(Homo sapiens)
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