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WRC:IRSp53/58:RAC1:GTP:PIP3 [plasma membrane]
Stable Identifier
R-DME-2029147
Type
Complex
Species
Drosophila melanogaster
Compartment
plasma membrane
Locations in the PathwayBrowser
Expand all
Immune System (Drosophila melanogaster)
Innate Immune System (Drosophila melanogaster)
Fcgamma receptor (FCGR) dependent phagocytosis (Drosophila melanogaster)
Regulation of actin dynamics for phagocytic cup formation (Drosophila melanogaster)
ABL phosphorylates WAVEs (Drosophila melanogaster)
WRC:IRSp53/58:RAC1:GTP:PIP3 [plasma membrane] (Drosophila melanogaster)
RAC1:GTP and PIP3 bind WAVE Regulatory Complex (WRC) (Drosophila melanogaster)
WRC:IRSp53/58:RAC1:GTP:PIP3 [plasma membrane] (Drosophila melanogaster)
Signal Transduction (Drosophila melanogaster)
Signaling by Receptor Tyrosine Kinases (Drosophila melanogaster)
Signaling by VEGF (Drosophila melanogaster)
VEGFA-VEGFR2 Pathway (Drosophila melanogaster)
RAC1:GTP and PIP3 bind WAVE Regulatory Complex (WRC) (Drosophila melanogaster)
WRC:IRSp53/58:RAC1:GTP:PIP3 [plasma membrane] (Drosophila melanogaster)
Signaling by Rho GTPases, Miro GTPases and RHOBTB3 (Drosophila melanogaster)
Signaling by Rho GTPases (Drosophila melanogaster)
RHO GTPase Effectors (Drosophila melanogaster)
RHO GTPases Activate WASPs and WAVEs (Drosophila melanogaster)
ABL phosphorylates WAVEs (Drosophila melanogaster)
WRC:IRSp53/58:RAC1:GTP:PIP3 [plasma membrane] (Drosophila melanogaster)
RAC1:GTP and PIP3 bind WAVE Regulatory Complex (WRC) (Drosophila melanogaster)
WRC:IRSp53/58:RAC1:GTP:PIP3 [plasma membrane] (Drosophila melanogaster)
General
This complex/polymer has been computationally inferred (based on PANTHER) from a complex/polymer involved in an event that has been demonstrated in another species.
Participants
components
IRSp53 [cytosol]
(Drosophila melanogaster)
PI(3,4,5)P3 [plasma membrane]
RAC1:GTP [plasma membrane]
(Drosophila melanogaster)
WAVE Regulatory Complex [cytosol]
(Drosophila melanogaster)
Participates
as an input of
ABL phosphorylates WAVEs (Drosophila melanogaster)
as an output of
RAC1:GTP and PIP3 bind WAVE Regulatory Complex (WRC) (Drosophila melanogaster)
Inferred From
WRC:IRSp53/58:RAC1:GTP:PIP3 [plasma membrane]
(Homo sapiens)
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