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Phospho (9 sites) SMO [plasma membrane]
Stable Identifier
R-DME-205802
Type
Protein [EntityWithAccessionedSequence]
Species
Drosophila melanogaster
Compartment
plasma membrane
Locations in the PathwayBrowser
Expand all
Drosophila signaling pathways (Drosophila melanogaster)
Hedgehog pathway (Drosophila melanogaster)
N-HH ligand bound to PTC receptor complex (Drosophila melanogaster)
Activation of CI (Drosophila melanogaster)
Dissociation of CI from COS (Drosophila melanogaster)
Phospho (9 sites) Act SMO:Phospho (2 sites) COS:CI:Phospho FU [plasma membrane] (Drosophila melanogaster)
Phospho (9 sites) SMO [plasma membrane] (Drosophila melanogaster)
Phospho (9 sites) Act SMO:Phospho (2 sites) COS:Phospho FU [plasma membrane] (Drosophila melanogaster)
Phospho (9 sites) SMO [plasma membrane] (Drosophila melanogaster)
Liberation of CI from SU(FU) repression (Drosophila melanogaster)
Phospho (9 sites) Act SMO:Phospho (2 sites) COS:Phospho FU [plasma membrane] (Drosophila melanogaster)
Phospho (9 sites) SMO [plasma membrane] (Drosophila melanogaster)
Activation of SMO (Drosophila melanogaster)
Autophosphorylated FU phosphorylates COS (Drosophila melanogaster)
Phospho (9 sites) Act SMO:COS:CI:FU [plasma membrane] (Drosophila melanogaster)
Phospho (9 sites) SMO [plasma membrane] (Drosophila melanogaster)
Phospho (9 sites) Act SMO:Phospho (2 sites) COS:CI:Phospho FU [plasma membrane] (Drosophila melanogaster)
Phospho (9 sites) SMO [plasma membrane] (Drosophila melanogaster)
Phosphorylated SMO changes conformation and is activated (Drosophila melanogaster)
Phospho (9 sites) Act SMO:COS:CI:FU [plasma membrane] (Drosophila melanogaster)
Phospho (9 sites) SMO [plasma membrane] (Drosophila melanogaster)
Phospho (9 sites) SMO:COS:CI:FU [plasma membrane] (Drosophila melanogaster)
Phospho (9 sites) SMO [plasma membrane] (Drosophila melanogaster)
Phosphorylation of SMO (Drosophila melanogaster)
Phosphorylation of SMO by CKIalpha (Drosophila melanogaster)
Phospho (9 sites) SMO:COS:CI:FU [plasma membrane] (Drosophila melanogaster)
Phospho (9 sites) SMO [plasma membrane] (Drosophila melanogaster)
External Reference Information
External Reference
UniProt:P91682 smo
Gene Names
smo, CG11561
Chain
signal peptide:1-31, chain:32-1036
Reference Genes
BioGPS Gene:33196 smo
KEGG Gene (Drosophila melanogaster):Dmel_CG11561 smo
Monarch:33196 smo
NCBI Gene:33196 smo
UCSC:P91682 smo
Reference Transcript
RefSeq:NM_078719.4 smo
Other Identifiers
154678_at
1634442_at
33196
GO:0000278
GO:0001745
GO:0001746
GO:0002376
GO:0002385
GO:0004888
GO:0004930
GO:0005113
GO:0005515
GO:0005886
GO:0005929
GO:0007165
GO:0007166
GO:0007186
GO:0007193
GO:0007224
GO:0007346
GO:0007350
GO:0007367
GO:0007389
GO:0007417
GO:0007455
GO:0007476
GO:0008289
GO:0009888
GO:0010628
GO:0012501
GO:0016020
GO:0019901
GO:0022414
GO:0023052
GO:0030154
GO:0030424
GO:0030425
GO:0030707
GO:0035019
GO:0042802
GO:0042803
GO:0042981
GO:0042995
GO:0043025
GO:0043226
GO:0045880
GO:0048099
GO:0048100
GO:0048856
GO:0051716
GO:0060089
GO:0070273
GO:0071679
GO:0072659
GO:0120025
GO:1903078
GO:2000134
GO:2000736
Participates
as a component of
Phospho (9 sites) SMO:COS:CI:FU [plasma membrane] (Drosophila melanogaster)
Phospho (9 sites) Act SMO:COS:CI:FU [plasma membrane] (Drosophila melanogaster)
Phospho (9 sites) Act SMO:Phospho (2 sites) COS:Phospho FU [plasma membrane] (Drosophila melanogaster)
Phospho (9 sites) Act SMO:Phospho (2 sites) COS:CI:Phospho FU [plasma membrane] (Drosophila melanogaster)
Other forms of this molecule
SMO [plasma membrane]
Phospho (3 sites) SMO [plasma membrane]
smo [ciliary membrane]
smo [ciliary tip]
smo [endocytic vesicle membrane]
phospho-smo [ciliary membrane]
Modified Residues
Name
O-phospho-L-serine at 667
Coordinate
667
PsiMod Name
O-phospho-L-serine [MOD:00046]
PsiMod Definition
A protein modification that effectively converts an L-serine residue to O-phospho-L-serine.
Name
O-phospho-L-serine at 687
Coordinate
687
PsiMod Name
O-phospho-L-serine [MOD:00046]
PsiMod Definition
A protein modification that effectively converts an L-serine residue to O-phospho-L-serine.
Name
O-phospho-L-serine at 740
Coordinate
740
PsiMod Name
O-phospho-L-serine [MOD:00046]
PsiMod Definition
A protein modification that effectively converts an L-serine residue to O-phospho-L-serine.
Name
O-phospho-L-serine at 670
Coordinate
670
PsiMod Name
O-phospho-L-serine [MOD:00046]
PsiMod Definition
A protein modification that effectively converts an L-serine residue to O-phospho-L-serine.
Name
O-phospho-L-serine at 673
Coordinate
673
PsiMod Name
O-phospho-L-serine [MOD:00046]
PsiMod Definition
A protein modification that effectively converts an L-serine residue to O-phospho-L-serine.
Name
O-phospho-L-serine at 690
Coordinate
690
PsiMod Name
O-phospho-L-serine [MOD:00046]
PsiMod Definition
A protein modification that effectively converts an L-serine residue to O-phospho-L-serine.
Name
O-phospho-L-serine at 693
Coordinate
693
PsiMod Name
O-phospho-L-serine [MOD:00046]
PsiMod Definition
A protein modification that effectively converts an L-serine residue to O-phospho-L-serine.
Name
O-phospho-L-serine at 743
Coordinate
743
PsiMod Name
O-phospho-L-serine [MOD:00046]
PsiMod Definition
A protein modification that effectively converts an L-serine residue to O-phospho-L-serine.
Name
O-phospho-L-serine at 746
Coordinate
746
PsiMod Name
O-phospho-L-serine [MOD:00046]
PsiMod Definition
A protein modification that effectively converts an L-serine residue to O-phospho-L-serine.
Cross References
RefSeq
NP_523443.1
Flybase
FBgn0003444
PRO
P91682
PDB
2MAH
,
8OIJ
Interactors (5)
Accession
#Entities
Entities
Confidence Score
Evidence (IntAct)
UniProt:P91682 smo
7
SMO [plasma membrane]
(R-DME-206086)
Phospho (3 sites) SMO [plasma membrane]
(R-DME-206009)
Phospho (9 sites) SMO [plasma membrane]
(R-DME-205802)
smo [ciliary membrane]
(R-DME-5624094)
smo [ciliary tip]
(R-DME-5610419)
smo [endocytic vesicle membrane]
(R-DME-5610422)
phospho-smo [ciliary membrane]
(R-DME-5632528)
0.73
8
UniProt:O16844 cos
2
Phospho (2 sites) COS [cytosol]
(R-DME-206282)
COS [cytosol]
(R-DME-205832)
0.704
7
UniProt:Q9VDD8
2
phospho-Usp8 [cytosol]
(R-DME-1358714)
Usp8 [cytosol]
(R-DME-917720)
0.656
4
UniProt:P68198 UBIQ
0.589
4
UniProt:P23647 fu
2
Phospho FU [cytosol]
(R-DME-205779)
FU [cytosol]
(R-DME-205872)
0.527
5
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