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PKA-C1 [cytosol]
Stable Identifier
R-DME-205931
Type
Protein [EntityWithAccessionedSequence]
Species
Drosophila melanogaster
Compartment
cytosol
Locations in the PathwayBrowser
Expand all
Drosophila signaling pathways (Drosophila melanogaster)
Hedgehog pathway (Drosophila melanogaster)
N-HH ligand bound to PTC receptor complex (Drosophila melanogaster)
Activation of SMO (Drosophila melanogaster)
Phosphorylation of SMO (Drosophila melanogaster)
Phosphorylation of SMO by PKA-C1 (Drosophila melanogaster)
PKA-C1 [cytosol] (Drosophila melanogaster)
N-HH ligand not bound to PTC receptor complex (Drosophila melanogaster)
Assembly of the CI containing complexes (Drosophila melanogaster)
Formation of the 'scaffold complex' (Drosophila melanogaster)
COS:CI:FU:PKA-C1:SGG:CKIalpha:DCO [cytosol] (Drosophila melanogaster)
PKA-C1 [cytosol] (Drosophila melanogaster)
PKA-C1 [cytosol] (Drosophila melanogaster)
Phosphorylation of CI (Drosophila melanogaster)
Further phosphorylation of CI by CKIalphaepsilon (Drosophila melanogaster)
COS:Phospho (13 sites) CI:FU:PKA-C1:SGG:CKIalpha:DCO [cytosol] (Drosophila melanogaster)
PKA-C1 [cytosol] (Drosophila melanogaster)
COS:Phospho (16 sites) CI:FU:PKA-C1:SGG:CKIalpha:DCO [cytosol] (Drosophila melanogaster)
PKA-C1 [cytosol] (Drosophila melanogaster)
Phosphorylation of CI by CKIalphaepsilon (CKIalpha/DCO) (Drosophila melanogaster)
COS:Phospho (11 sites) CI:FU:PKA-C1:SGG:CKIalpha:DCO [cytosol] (Drosophila melanogaster)
PKA-C1 [cytosol] (Drosophila melanogaster)
COS:Phospho (3 sites) CI:FU:PKA-C1:SGG:CKIalpha:DCO [cytosol] (Drosophila melanogaster)
PKA-C1 [cytosol] (Drosophila melanogaster)
Phosphorylation of CI by PKA-C1 (Drosophila melanogaster)
COS:CI:FU:PKA-C1:SGG:CKIalpha:DCO [cytosol] (Drosophila melanogaster)
PKA-C1 [cytosol] (Drosophila melanogaster)
COS:Phospho (3 sites) CI:FU:PKA-C1:SGG:CKIalpha:DCO [cytosol] (Drosophila melanogaster)
PKA-C1 [cytosol] (Drosophila melanogaster)
PKA-C1 [cytosol] (Drosophila melanogaster)
Phosphorylation of CI by SGG (Drosophila melanogaster)
COS:Phospho (11 sites) CI:FU:PKA-C1:SGG:CKIalpha:DCO [cytosol] (Drosophila melanogaster)
PKA-C1 [cytosol] (Drosophila melanogaster)
COS:Phospho (13 sites) CI:FU:PKA-C1:SGG:CKIalpha:DCO [cytosol] (Drosophila melanogaster)
PKA-C1 [cytosol] (Drosophila melanogaster)
Ubiquitination and proteolysis of phosphorylated CI (Drosophila melanogaster)
SLMB binds to and ubiquitinates phosphorylated CI (Drosophila melanogaster)
COS:Phospho (16 sites) CI:FU:PKA-C1:SGG:CKIalpha:DCO [cytosol] (Drosophila melanogaster)
PKA-C1 [cytosol] (Drosophila melanogaster)
SLMB:SKPA:LIN19:ROC1A:EFF:COS:Phospho (16 sites) CI:UBI-P63E:FU:PKA-C1:SGG:CKIalpha:DCO [cytosol] (Drosophila melanogaster)
COS:Phospho (16 sites) CI:FU:PKA-C1:SGG:CKIalpha:DCO [cytosol] (Drosophila melanogaster)
PKA-C1 [cytosol] (Drosophila melanogaster)
Ubiquitinated and phosphorylated CI is partially degraded by the proteasome complex (Drosophila melanogaster)
COS:FU:PKA-C1:SGG:CKIalpha:DCO [cytosol] (Drosophila melanogaster)
PKA-C1 [cytosol] (Drosophila melanogaster)
SLMB:SKPA:LIN19:ROC1A:EFF:COS:Phospho (16 sites) CI:UBI-P63E:FU:PKA-C1:SGG:CKIalpha:DCO [cytosol] (Drosophila melanogaster)
COS:Phospho (16 sites) CI:FU:PKA-C1:SGG:CKIalpha:DCO [cytosol] (Drosophila melanogaster)
PKA-C1 [cytosol] (Drosophila melanogaster)
External Reference Information
External Reference
UniProt:P12370 Pka-C1
Gene Names
Pka-C1, CdkA, DC0, CG4379
Chain
initiator methionine:, chain:2-353
Reference Genes
BioGPS Gene:34284 Pka-C1
CTD Gene:34284 Pka-C1
KEGG Gene (Drosophila melanogaster):Dmel_CG4379 Pka-C1
Monarch:34284 Pka-C1
NCBI Gene:34284 Pka-C1
UCSC:P12370 Pka-C1
Reference Transcript
RefSeq:NM_164866.3 Pka-C1
RefSeq:NM_057629.4 Pka-C1
RefSeq:NM_205950.3 Pka-C1
Other Identifiers
143094_at
1631055_at
1632409_a_at
34284
GO:0000166
GO:0003824
GO:0004672
GO:0004674
GO:0004679
GO:0004691
GO:0005515
GO:0005524
GO:0005634
GO:0005829
GO:0005886
GO:0005952
GO:0006468
GO:0006913
GO:0007010
GO:0007163
GO:0007314
GO:0007317
GO:0007448
GO:0007476
GO:0007615
GO:0007622
GO:0008103
GO:0008355
GO:0008359
GO:0010628
GO:0010737
GO:0012501
GO:0016301
GO:0016310
GO:0016740
GO:0019933
GO:0022414
GO:0023052
GO:0030154
GO:0030163
GO:0030425
GO:0032436
GO:0032956
GO:0035332
GO:0036211
GO:0040040
GO:0042981
GO:0043005
GO:0043025
GO:0043226
GO:0044297
GO:0045187
GO:0045879
GO:0045880
GO:0046823
GO:0048477
GO:0048682
GO:0048856
GO:0050804
GO:0050877
GO:0071361
GO:0106310
GO:0140096
GO:2000249
Participates
as a component of
COS:FU:PKA-C1:SGG:CKIalpha:DCO [cytosol] (Drosophila melanogaster)
COS:CI:FU:PKA-C1:SGG:CKIalpha:DCO [cytosol] (Drosophila melanogaster)
COS:Phospho (3 sites) CI:FU:PKA-C1:SGG:CKIalpha:DCO [cytosol] (Drosophila melanogaster)
COS:Phospho (11 sites) CI:FU:PKA-C1:SGG:CKIalpha:DCO [cytosol] (Drosophila melanogaster)
COS:Phospho (13 sites) CI:FU:PKA-C1:SGG:CKIalpha:DCO [cytosol] (Drosophila melanogaster)
COS:Phospho (16 sites) CI:FU:PKA-C1:SGG:CKIalpha:DCO [cytosol] (Drosophila melanogaster)
as an input of
Formation of the 'scaffold complex' (Drosophila melanogaster)
Other forms of this molecule
PRKACA [mitochondrial matrix]
PRKACA [ciliary base]
PRKACA [nucleoplasm]
PRKACA [cytosol]
Cross References
RefSeq
NP_476977.1
,
NP_995672.1
,
NP_723479.1
Flybase
FBgn0000273
PRO
P12370
Interactors (2)
Accession
#Entities
Entities
Confidence Score
Evidence (IntAct)
UniProt:Q03720
1
slo [plasma membrane]
(R-DME-2534368)
0.685
6
UniProt:P81900
4
PRKAR2B [ciliary base]
(R-DME-5610414)
PRKAR2A [ciliary base]
(R-DME-5610412)
PRKAR2A [cytosol]
(R-DME-57840)
PRKAR2B [cytosol]
(R-DME-57842)
0.592
4
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